phosphoserine has been researched along with sirolimus in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (14.29) | 18.2507 |
| 2000's | 15 (53.57) | 29.6817 |
| 2010's | 9 (32.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giasson, E; Meloche, S | 1 |
| Cohen, P; Saito, Y; Vandenheede, JR | 1 |
| Bertram, PG; Shaw, AS; Thorson, J; Zeng, C; Zheng, XF | 1 |
| Cichy, SC; Cohen, P; Guo, S; Rena, G; Unterman, TG | 1 |
| Avruch, J; Reeves, SA; Wakisaka, S; Yokogami, K | 1 |
| Astoul, E; Cantrell, D; Lafont, V; Laurence, A; Liautard, J | 1 |
| Berg, CE; Lavan, BE; Rondinone, CM | 1 |
| Marignani, PA; Scheid, MP; Woodgett, JR | 1 |
| Baraban, JM; Beretta, L; Dy, M; Grolleau, A; Machavoine, F; Rolli-Derkinderen, M | 1 |
| Chen, SR; Sutherland, C; Walsh, MP; Xiao, B | 1 |
| Gingras, AC; Hershey, JW; Livingstone, M; Mayeur, GL; Peiretti, F; Polakiewicz, RD; Raught, B; Shahbazian, D; Sonenberg, N | 1 |
| Cao, X; Kambe, F; Moeller, LC; Refetoff, S; Seo, H | 1 |
| Alfonso, M; Campbell, DG; Cohen, P; Mora, A; Murray, JT; Peggie, M | 1 |
| Buchholz, M; Derin, R; Ghosh, P; Kusaba, H; Longo, DL; Madara, K; Sasaki, C | 1 |
| Funk, AP; Gera, JF; Jo, OD; Marderosian, M; Masri, J; Sharma, A; Vartanian, R | 1 |
| Blenis, J; Cohen, MS; Hershey, JW; Mieulet, V; Pende, M; Raught, B; Roux, PP; Shahbazian, D; Sonenberg, N; Taunton, J | 1 |
| Easton, JB; Houghton, PJ; Huang, S; Kriwacki, RW; Lacy, ER; Mishra, A; Xiao, L; Zhan, J | 1 |
| Harris, TE; Lawrence, JC; Sturgill, TW; Wang, L | 1 |
| Asara, JM; Dibble, CC; Manning, BD | 1 |
| Dao-Feng, B; Wei, D; Xin-Long, C; Zhao-Fan, X | 1 |
| Ammerer, G; Dohnal, I; Kaspar, S; Kijanska, M; Kraft, C; Peter, M; Reiter, W; Stoffel, I | 1 |
| Liu, X; Marzec, M; Odum, N; Rook, AH; Wasik, MA; Wysocka, M | 1 |
| Blazejczyk, M; Caban, B; Jaworski, J; Kazmierska, P; Konopacki, J; Macias, M; Rodo, A; Skalecka, A; Tarkowski, B | 1 |
| Aburatani, H; Arimoto, T; Fujii, T; Fukuda, T; Hirota, Y; Ikeda, Y; Inaba, K; Kashiyama, T; Kawana, K; Koso, T; Kurikawa, R; Makii, C; Matsuda, K; McCormick, F; Miyasaka, A; Nakagawa, S; Oda, K; Osuga, Y; Shiose, Y; Shoji, K; Sone, K; Tanikawa, M; Wada-Hiraike, O; Yano, T | 1 |
| Bartlett, DL; Kim, SY; Kwon, YT; Lee, YJ; Song, X; Tang, D; Zhang, L | 1 |
| Huang, S; Kazimierczak, U; Koromilas, AE; Krishnamoorthy, J; Papadakis, AI; Rajesh, K; Tenkerian, C; Wang, S | 1 |
| Abu Shehab, M; Biggar, KK; Damerill, I; Gupta, MB; Jansson, T; Li, SS | 1 |
| Dai, X; Ding, Y; Han, YM; Ouyang, C; Wang, Q; Wu, S; Xie, Z; Zhu, H; Zou, MH | 1 |
28 other study(ies) available for phosphoserine and sirolimus
| Article | Year |
|---|---|
Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Imidazoles; Kinetics; Losartan; Male; Molecular Weight; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred BN; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; Sirolimus; Tetrazoles; Tyrosine | 1995 |
The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Epidermal Growth Factor; Ethers, Cyclic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Immunosuppressive Agents; Kinetics; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Polyenes; Protein Phosphatase 1; Radioisotope Dilution Technique; Sirolimus; Tumor Cells, Cultured | 1994 |
The 14-3-3 proteins positively regulate rapamycin-sensitive signaling.
Topics: 14-3-3 Proteins; Binding Sites; Drug Resistance, Microbial; Enzyme Inhibitors; Female; Fungal Proteins; Genes, Fungal; Humans; Immunophilins; Ligands; Phosphatidylinositol 3-Kinases; Phosphoserine; Phosphotransferases (Alcohol Group Acceptor); Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Sirolimus; Tacrolimus Binding Proteins; Tyrosine 3-Monooxygenase | 1998 |
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Androstadienes; Antibody Specificity; bcl-Associated Death Protein; Caenorhabditis elegans Proteins; Carrier Proteins; Consensus Sequence; DNA-Binding Proteins; Enzyme Activation; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Insulin-Like Growth Factor I; Molecular Sequence Data; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Serine; Signal Transduction; Sirolimus; Threonine; Transcription Factors; Wortmannin | 1999 |
Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR.
Topics: Cell Line; Ciliary Neurotrophic Factor; DNA-Binding Proteins; Humans; MAP Kinase Signaling System; Peptide Fragments; Phosphorylation; Phosphoserine; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Sirolimus; STAT3 Transcription Factor; TOR Serine-Threonine Kinases; Trans-Activators | 2000 |
The T cell antigen receptor activates phosphatidylinositol 3-kinase-regulated serine kinases protein kinase B and ribosomal S6 kinase 1.
Topics: Antibodies; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Molecular Weight; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Antigen, T-Cell; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; T-Lymphocytes | 2000 |
Rapamycin partially prevents insulin resistance induced by chronic insulin treatment.
Topics: Adipocytes; Animals; Biological Transport; Cell Line; Glucose; Insulin; Insulin Antagonists; Insulin Resistance; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sirolimus; Time Factors | 2002 |
Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Binding Sites; Cattle; Cell Line; Cell Membrane; Dimerization; Enzyme Activation; Enzyme Inhibitors; Humans; Insulin-Like Growth Factor I; Kidney; Membrane Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Interaction Mapping; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Recombinant Fusion Proteins; Sirolimus; Tacrolimus Binding Protein 1A; Tamoxifen; TOR Serine-Threonine Kinases; Transfection | 2002 |
ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1.
Topics: Adaptor Proteins, Signal Transducing; Base Sequence; Blotting, Northern; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Cell Line; Chromones; Cycloheximide; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histidine Decarboxylase; Humans; Hypotonic Solutions; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 11; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Morpholines; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphoserine; Promoter Regions, Genetic; Repressor Proteins; Response Elements; RNA, Messenger; Sirolimus; Tetradecanoylphorbol Acetate; Transcription Factors | 2003 |
Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6).
Topics: Amino Acid Substitution; Animals; Antigen-Antibody Reactions; Calcium Signaling; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dogs; Humans; Kidney; Macromolecular Substances; Mice; Mutation, Missense; Myocytes, Cardiac; Phosphorylation; Phosphoserine; Point Mutation; Protein Binding; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sirolimus; Structure-Activity Relationship; Tacrolimus Binding Proteins | 2004 |
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases.
Topics: Cell Line; Drug Resistance; Eukaryotic Initiation Factors; Humans; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Protein Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2004 |
Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts.
Topics: Active Transport, Cell Nucleus; Cells, Cultured; Cycloheximide; Enzyme Activation; Fibroblasts; Gene Expression Regulation; Humans; Ligands; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoserine; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Protein Subunits; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Thyroid Hormone Receptors beta; Time Factors; TOR Serine-Threonine Kinases; Triiodothyronine | 2005 |
Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Androstadienes; Animals; Antibody Specificity; Benzamides; Cell Extracts; Cell Line; Contractile Proteins; Epidermal Growth Factor; Filamins; Humans; Immediate-Early Proteins; Insulin; Isoenzymes; Mice; Microfilament Proteins; Molecular Sequence Data; Molecular Weight; Muscle, Skeletal; Myoblasts; Myocardium; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rabbits; Signal Transduction; Sirolimus; Substrate Specificity; Wortmannin | 2004 |
Interleukin-12-induced interferon-gamma production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR).
Topics: CD28 Antigens; Cells, Cultured; Cyclosporine; DNA-Binding Proteins; Humans; Interferon-gamma; Interleukin-12; Lymphocyte Activation; Phosphorylation; Phosphoserine; Promoter Regions, Genetic; Protein Kinases; Sirolimus; STAT3 Transcription Factor; STAT4 Transcription Factor; T-Lymphocytes; TOR Serine-Threonine Kinases; Trans-Activators; Transcription Factors | 2005 |
Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling.
Topics: 14-3-3 Proteins; Animals; Cell Line; Cyclin D; Cyclins; Dactinomycin; Embryo, Mammalian; Fibroblasts; Genes, bcl-1; Genes, myc; Genes, Reporter; Half-Life; Imidazoles; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Protein Binding; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridines; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Ribosomes; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sirolimus; Tristetraprolin | 2006 |
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Animals; Catalysis; Eukaryotic Initiation Factor-3; Eukaryotic Initiation Factors; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Sirolimus; TOR Serine-Threonine Kinases | 2006 |
Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo.
Topics: Anthracenes; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; Mutation; Nuclear Localization Signals; Phosphoserine; Protein Binding; Protein Kinase Inhibitors; Sirolimus | 2007 |
Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR.
Topics: Animals; Cell Line; Humans; Mice; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Kinases; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Substrate Specificity; TOR Serine-Threonine Kinases; Transcription Factors | 2009 |
Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Carrier Proteins; Chromatography, Liquid; Conserved Sequence; HeLa Cells; Humans; Insulin; Intercellular Signaling Peptides and Proteins; Mass Spectrometry; Mice; Models, Biological; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Proto-Oncogene Proteins c-akt; Rapamycin-Insensitive Companion of mTOR Protein; Ribosomal Protein S6 Kinases, 90-kDa; Sirolimus; Vertebrates | 2009 |
mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn.
Topics: Animals; Anti-Bacterial Agents; Blotting, Western; Burns; C-Peptide; Disease Models, Animal; Glucose Clamp Technique; Immunohistochemistry; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Muscle, Skeletal; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Serine; Sirolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2011 |
Activation of Atg1 kinase in autophagy by regulated phosphorylation.
Topics: Amino Acid Sequence; Autophagy; Autophagy-Related Proteins; Conserved Sequence; Enzyme Activation; Molecular Sequence Data; Mutation; Phagosomes; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinases; Protein Transport; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Sirolimus | 2010 |
Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Eukaryotic Initiation Factor-4E; Humans; Intracellular Signaling Peptides and Proteins; Lymphoma, T-Cell, Cutaneous; Mechanistic Target of Rapamycin Complex 1; Mitogen-Activated Protein Kinase Kinases; Multiprotein Complexes; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proteins; Sirolimus; TOR Serine-Threonine Kinases | 2011 |
Spatiotemporal characterization of mTOR kinase activity following kainic acid induced status epilepticus and analysis of rat brain response to chronic rapamycin treatment.
Topics: Animals; Astrocytes; Brain; Cell Death; Cell Nucleus; Hippocampus; Kainic Acid; Male; Neurons; Phosphorylation; Phosphoserine; Rats; Rats, Wistar; Ribosomal Protein S6; Seizures; Signal Transduction; Sirolimus; Spatio-Temporal Analysis; Status Epilepticus; Subcellular Fractions; TOR Serine-Threonine Kinases | 2013 |
Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423.
Topics: Adenocarcinoma, Clear Cell; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; DNA Mutational Analysis; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Mice, Nude; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Protein Kinase Inhibitors; RNA, Messenger; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2014 |
Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Boronic Acids; Bortezomib; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Enzyme Activation; Humans; Kinetics; Melphalan; Membrane Proteins; Mice; Mitochondria; Phosphorylation; Phosphoserine; Pyrazines; Sirolimus | 2014 |
Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress.
Topics: Activating Transcription Factor 4; Animals; Cell Death; Cell Lineage; Cell Survival; eIF-2 Kinase; Enzyme Activation; Eukaryotic Initiation Factor-2; Gene Deletion; Humans; Mechanistic Target of Rapamycin Complex 1; Mice; Models, Biological; Multiprotein Complexes; Oxidants; Oxidative Stress; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Sirolimus; TOR Serine-Threonine Kinases | 2015 |
Hypoxia Increases IGFBP-1 Phosphorylation Mediated by mTOR Inhibition.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cell Hypoxia; Gene Silencing; Hep G2 Cells; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Molecular Sequence Data; Multiprotein Complexes; Papio; Phosphorylation; Phosphoserine; Rapamycin-Insensitive Companion of mTOR Protein; Receptor, IGF Type 1; Regulatory-Associated Protein of mTOR; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2016 |
Deletion of PRKAA triggers mitochondrial fission by inhibiting the autophagy-dependent degradation of DNM1L.
Topics: AMP-Activated Protein Kinases; Animals; Aorta; Autophagy; Cell Separation; Dynamins; Endothelium, Vascular; Gene Deletion; GTP Phosphohydrolases; Human Umbilical Vein Endothelial Cells; Humans; Mice, Inbred C57BL; Microtubule-Associated Proteins; Mitochondrial Dynamics; Mitochondrial Proteins; Phosphorylation; Phosphoserine; Proteolysis; Sequestosome-1 Protein; Sirolimus; Vasodilation | 2017 |