phosphoserine and epidermal growth factor

phosphoserine has been researched along with epidermal growth factor in 67 studies

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-19906 (8.96)18.7374
1990's22 (32.84)18.2507
2000's25 (37.31)29.6817
2010's14 (20.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bird, TA; Saklatvala, J1
Mendelsohn, J; Peacock, JS; Sunada, H; Yu, P1
Clinton, GM; Li, SW; Lin, YZ1
Iwashita, S; Mitsui, K1
Ballou, LM; Luther, H; Thomas, G1
Contreras, ML; Fink, D; Guroff, G; Kim, HS; Kim, UH; Park, DJ; Rhee, SG1
Abdel-Ghany, M; Koland, J; Racker, E; Revis-Gupta, S1
Anderson, NG; Erickson, AK; Ray, LB; Sturgill, TW1
Erickson, AK; Ray, LB; Sturgill, TW1
Cohen, S; Sawyer, ST1
Hollenberg, MD; Pallen, CJ; Valentine, KA; Wang, JH1
David-Pfeuty, T; Guesdon, F1
Chong, SM; Khanna, NC; Tokuda, M; Waisman, DM1
Blackshear, PJ; Girard, PR; Kuo, JF; Quamo, SN; Witters, LA1
Alitalo, K; Bornstein, P; Keski-Oja, J1
Cuveele, JF; de Witte, PA; Merlevede, WJ; Vandenheede, JR1
Ploegh, HL; Schaap, D; van Blitterswijk, WJ; van der Bend, RL; van der Wal, J1
Cohen, P; Saito, Y; Vandenheede, JR1
Hayashi, T; Imura, H; Inoue, G; Kono, S; Kosaki, A; Kuzuya, H; Nishimura, H; Okamoto, M; Yamada, K; Yoshimasa, Y1
Ascoli, M; Hoelscher, SR1
McCormick, F; Porfiri, E1
Beery, R; Geier, A; Haimsohn, M; Hemi, R; Karasik, A1
Balaban, N; Goldkorn, T; Matsukuma, K; Shannon, M1
Mollerup, S; Rivedal, E; Sanner, T; Vikhamar, G1
Allis, CD; Bazett-Jones, DP; Chadee, DN; Davie, JR; Hendzel, MJ; Tylipski, CP; Wright, JA1
Mercurio, AM; Rabinovitz, I; Toker, A1
Cao, X; Lim, CP1
Moelling, K; Zimmermann, S1
Dalakas, MC; Li, M1
Cochran, BH; Fanburg, BL; Guan, KL; Simon, AR; Stewart, S; Vikis, HG1
Berg, AH; Engelman, JA; Lewis, RY; Lisanti, MP; Scherer, PE1
Chung, J; Jee, K; Kim, D; Kim, S; Koh, H1
Epstein, RJ; Gulliford, T; Huang, G; Ouyang, X; Smith, G; Zhang, H1
Felts, N; Floyd, RA; Hensley, K; Pye, QN; Salsman, S1
Luo, Z; Ruderman, N; Song, Y; Wen, R; Xiang, X; Yuan, M1
Kim, YH; Kim, YS; Lee, YH; Shin, SY; Yoon, SC1
Frank, SJ; Huang, Y; Jiang, J; Kim, SO1
Hunger-Glaser, I; Rozengurt, E; Salazar, EP; Sinnett-Smith, J1
Abrahamsen, H; Andersson, Y; Christoffersen, T; Guren, TK; Susa, M; Thoresen, GH; Ødegård, J; Østby, E1
Halldórsson, H; Thorgeirsson, G; Thors, B1
Alfonso, M; Campbell, DG; Cohen, P; Mora, A; Murray, JT; Peggie, M1
Ando, Y; Fujii, Y; Hamaguchi, M; Iwase, H; Kobayashi, S; Mita, K; Nishio, M; Sugiura, H; Yamashita, H; Zhang, Z1
Argetsinger, LS; Carter-Su, C; Cline, JM; Jensen, ON; Kouadio, JL; Mazurkiewicz-Munoz, AM; Stensballe, A1
Betapudi, V; Bresnick, AR; Dulyaninova, NG; House, RP1
Kuikman, I; Litjens, SH; Margadant, C; Sonnenberg, A; van Rheenen, J; Wilhelmsen, K1
Kitamura, N; Komada, M; Mizuno, E1
Carr, HS; Dan, I; Frost, JA; Ruvolo, PP; Wu, X1
Jang, IH; Jung, H; Lee, HY; Ryu, SH; Suh, PG1
Ge, BX; Huang, Z; Yan, DP1
Chen, C; Gong, J; Huang, Q; Huang, W; Luo, L; Luo, X; Luo, Z; Olbrot, M; Peng, Y; Xiang, X; Zang, M; Zhou, J1
Bai, X; Beryt, M; Brdlik, C; Higaki, JN; Jin, P; Jorgensen, B; Kumari, R; Lau, FW; Lindley, P; Liu, J; Ni, I; Rozzelle, J; Sarup, J; Shepard, HM; Turin, L; Watson, SA; Zhang, J1
Moran, MF; Peterman, SM; Prakash, A; Taylor, P; Tong, J1
Abdel Fattah, E; Eissa, NT; Gorgun, FM; Mazumdar, T; Pandit, L; Tyryshkin, A; Zeng, S1
Aldape, K; Fang, B; Fang, D; Fang, X; Ge, Q; Hawke, D; Ji, H; Keezer, S; Litchfield, DW; Lu, Z; Nika, H; Wang, J1
Flinder, LI; Huitfeldt, HS; Rosseland, CM; Skarpen, E; Timofeeva, OA; Wierød, L1
Dunn, TJ; Gao, J; Gao, T; Hooten, KG; Ojeda, L; Thonhoff, JR; Wang, E; Wu, P1
Ishigaki, Y; Kajinami, K; Kawai, Y; Takata, T; Takeda, K1
Kim, JH; Kim, YB; Shin, YJ1
Anichini, A; Canevari, S; Rea, K; Sensi, M; Tomassetti, A1
Corson, GM; Mandel, G; McCleskey, M; Nesti, E; Oyer, JA1
Besik, V; Breit, A; Glas, E; Gudermann, T; Muehlich, S; Solinski, HJ; Yarwood, SJ1
Chen, Y; Qian, H; Wu, M; Wu, Y; Yao, X; Zhu, M1
Ji, H; Lee, JH; Lu, Z; Lyu, J; Pang, Y; Wang, Y; Xia, Y; Zhang, T; Zhong, L1
Hamaoka, Y; Katoh, H; Negishi, M1
Cao, R; Li, X; Liang, J; Lu, Z; Wang, L; Xia, Y; Yang, W; Zhang, Y; Zheng, Y1
Frost, JA; Oh, W; Ulu, A; Zuo, Y1
Cai, Z; Han, F; Jin, G; Li, CF; Lin, HK; Morrow, J; Wang, CY; Wang, G; Xu, C; Xu, D; Zhang, S; Zhang, WN; Zhang, X1

Trials

1 trial(s) available for phosphoserine and epidermal growth factor

ArticleYear
The muscle mitogen-activated protein kinase is altered in sporadic inclusion body myositis.
    Neurology, 2000, Apr-25, Volume: 54, Issue:8

    Topics: Aged; Animals; Biopsy; Blotting, Western; Cytoskeletal Proteins; Epidermal Growth Factor; Fluorescent Antibody Technique, Indirect; Humans; Immunohistochemistry; Middle Aged; Mitogen-Activated Protein Kinases; Muscle Fibers, Skeletal; Muscle, Skeletal; Myositis, Inclusion Body; PC12 Cells; Phosphorylation; Phosphoserine; Rats; Vacuoles

2000

Other Studies

66 other study(ies) available for phosphoserine and epidermal growth factor

ArticleYear
Down-modulation of epidermal growth factor receptor affinity in fibroblasts treated with interleukin 1 or tumor necrosis factor is associated with phosphorylation at a site other than threonine 654.
    The Journal of biological chemistry, 1990, Jan-05, Volume: 265, Issue:1

    Topics: Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gingiva; Humans; Interleukin-1; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha; Tyrosine

1990
Modulation of tyrosine, serine, and threonine phosphorylation and intracellular processing of the epidermal growth factor receptor by antireceptor monoclonal antibody.
    Journal of cellular physiology, 1990, Volume: 142, Issue:2

    Topics: Antibodies, Monoclonal; Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Half-Life; Methylamines; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine

1990
Insulin and epidermal growth factor stimulate phosphorylation of p185HER-2 in the breast carcinoma cell line, BT474.
    Molecular and cellular endocrinology, 1990, Mar-05, Volume: 69, Issue:2-3

    Topics: Blood; Breast Neoplasms; Epidermal Growth Factor; ErbB Receptors; Humans; Insulin; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, ErbB-2; Tumor Cells, Cultured; Tyrosine

1990
Examination of the role of serine phosphorylation in phospholipase C-gamma and its related P47 in cAMP-mediated depression of epidermal growth factor signal transduction.
    FEBS letters, 1990, Jul-30, Volume: 268, Issue:1

    Topics: Colforsin; Cross Reactions; Epidermal Growth Factor; ErbB Receptors; Humans; In Vitro Techniques; Molecular Weight; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphotyrosine; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine

1990
MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways.
    Nature, 1991, Jan-24, Volume: 349, Issue:6307

    Topics: Adipose Tissue; Animals; Blood; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Enzyme Reactivators; Epidermal Growth Factor; Fibroblasts; Insulin; Mice; Oocytes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Tyrosine; Xenopus

1991
Nerve growth factor stimulates phosphorylation of phospholipase C-gamma in PC12 cells.
    The Journal of biological chemistry, 1991, Jan-25, Volume: 266, Issue:3

    Topics: Animals; Blotting, Western; Cells, Cultured; Epidermal Growth Factor; In Vitro Techniques; Isoenzymes; Nerve Growth Factors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Type C Phospholipases; Tyrosine

1991
Heparin stimulates epidermal growth factor receptor-mediated phosphorylation of tyrosine and threonine residues.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Jul-15, Volume: 88, Issue:14

    Topics: Amino Acids; Animals; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Escherichia coli; Glutathione Transferase; Heparin; Humans; Insecta; Manganese; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Substrate Specificity; Threonine; Tyrosine

1991
Purification of mitogen-activated protein kinase from epidermal growth factor-treated 3T3-L1 fibroblasts.
    Methods in enzymology, 1991, Volume: 200

    Topics: 3T3 Cells; Animals; Autoradiography; Buffers; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Indicators and Reagents; Kinetics; Mice; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Tyrosine

1991
Microtubule-associated protein 1A is the fibroblast HMW MAP undergoing mitogen-stimulated serine phosphorylation.
    Biochemical and biophysical research communications, 1990, Jan-30, Volume: 166, Issue:2

    Topics: Animals; Epidermal Growth Factor; Fibroblasts; In Vitro Techniques; Insulin; Mice; Microtubule-Associated Proteins; Molecular Weight; Phosphoproteins; Phosphoserine; Precipitin Tests; Protein Kinases

1990
Epidermal growth factor stimulates the phosphorylation of the calcium-dependent 35,000-dalton substrate in intact A-431 cells.
    The Journal of biological chemistry, 1985, Jul-15, Volume: 260, Issue:14

    Topics: Animals; Autoradiography; Calcium; Cell Line; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Mice; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinases; Proteins; Time Factors; Tyrosine

1985
Calcineurin-mediated dephosphorylation of the human placental membrane receptor for epidermal growth factor urogastrone.
    Biochemistry, 1985, Aug-27, Volume: 24, Issue:18

    Topics: Brain; Calmodulin-Binding Proteins; Cations, Monovalent; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Kinetics; Phosphorylation; Phosphoserine; Phosphotyrosine; Placenta; Pregnancy; Receptors, Cell Surface; Tyrosine

1985
Epidermal growth factor stimulates serine and tyrosine phosphorylation in a 59-kD protein in purified plasma membranes from rat liver.
    Biochemical and biophysical research communications, 1987, Jun-15, Volume: 145, Issue:2

    Topics: Animals; Endopeptidases; Epidermal Growth Factor; Liver; Male; Membrane Proteins; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Rats, Inbred Strains; Serine; Serine Endopeptidases; Tyrosine

1987
Phosphorylation of p36 in vitro by protein kinase C.
    Biochemical and biophysical research communications, 1986, May-29, Volume: 137, Issue:1

    Topics: Animals; Cattle; Enzyme Activation; Epidermal Growth Factor; Lung; Nerve Tissue Proteins; Phosphoserine; Protein Kinase C; Protein-Tyrosine Kinases; Synapsins

1986
Growth factor-stimulated protein phosphorylation in 3T3-L1 cells. Evidence for protein kinase C-dependent and -independent pathways.
    The Journal of biological chemistry, 1985, Oct-25, Volume: 260, Issue:24

    Topics: Animals; Brain; Cell Line; Diglycerides; Enzyme Activation; Epidermal Growth Factor; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Humans; Immunologic Techniques; Insulin; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1985
Effects of Zn2+ ions on protein phosphorylation in epithelial cell membranes.
    Journal of cellular physiology, 1983, Volume: 115, Issue:3

    Topics: Animals; Cations, Divalent; Cell Division; Cell Line; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelium; ErbB Receptors; Membrane Proteins; Mice; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinases; Receptors, Cell Surface; Zinc

1983
Analysis of phosphorylhydroxyamino acids present in hydrolyzed cell extracts using dabsyl derivatization.
    Analytical biochemistry, 1995, Mar-20, Volume: 226, Issue:1

    Topics: Cell Extracts; Chromatography, Thin Layer; Electrophoresis; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; p-Dimethylaminoazobenzene; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Protein-Tyrosine Kinases; Quercetin; Tumor Cells, Cultured; Tyrosine

1995
Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon.
    The Biochemical journal, 1993, Feb-01, Volume: 289 ( Pt 3)

    Topics: 1-Methyl-3-isobutylxanthine; Antibodies, Monoclonal; Antibody Specificity; Cells, Cultured; Colforsin; Diacylglycerol Kinase; Epidermal Growth Factor; Epitopes; ErbB Receptors; Escherichia coli; Humans; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine

1993
The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells.
    The Biochemical journal, 1994, Oct-01, Volume: 303 ( Pt 1)

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Epidermal Growth Factor; Ethers, Cyclic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Immunosuppressive Agents; Kinetics; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Polyenes; Protein Phosphatase 1; Radioisotope Dilution Technique; Sirolimus; Tumor Cells, Cultured

1994
Preparation of anti-phosphoserine and anti-phosphothreonine antibodies and their application in the study of insulin- and EGF-induced phosphorylation.
    Biochemical and biophysical research communications, 1993, Jan-15, Volume: 190, Issue:1

    Topics: Animals; Antibodies; CHO Cells; Chromatography, Affinity; Cricetinae; Epidermal Growth Factor; ErbB Receptors; Humans; Insulin; Kinetics; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Rabbits; Receptor, Insulin; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1993
Identification of a Leydig tumor cell protein that is phosphorylated in response to stimulation with choriogonadotropin or epidermal growth factor.
    Endocrinology, 1993, Volume: 132, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arginine Vasopressin; Chorionic Gonadotropin; Electrophoresis, Gel, Two-Dimensional; Epidermal Growth Factor; Insulin; Kinetics; Leydig Cell Tumor; Mice; Peptide Mapping; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Tumor Cells, Cultured

1993
Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1.
    The Journal of biological chemistry, 1996, Mar-08, Volume: 271, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chlorocebus aethiops; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; ErbB Receptors; GRB2 Adaptor Protein; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Humans; Kinetics; Mice; Mutagenesis; Peptide Mapping; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Biosynthesis; Proteins; ras Guanine Nucleotide Exchange Factors; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Deletion; Sequence Tagged Sites; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection

1996
Phosphorylation of A 27-kDa protein correlates with survival of protein-synthesis-inhibited MCF-7 cells.
    In vitro cellular & developmental biology. Animal, 1997, Volume: 33, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aurintricarboxylic Acid; Breast Neoplasms; Carcinoma; Cell Survival; Cycloheximide; Cytosol; Epidermal Growth Factor; Heat-Shock Proteins; Humans; Insulin-Like Growth Factor I; Isoelectric Point; Mitogens; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Synthesis Inhibitors; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1997
EGF receptor phosphorylation is affected by ionizing radiation.
    Biochimica et biophysica acta, 1997, Oct-11, Volume: 1358, Issue:3

    Topics: Adenosine Triphosphate; Cell Division; Cell Line; Cell Membrane; Cesium Radioisotopes; Dose-Response Relationship, Radiation; Epidermal Growth Factor; ErbB Receptors; Gamma Rays; Humans; Kinetics; Methionine; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine

1997
Role of Cx43 phosphorylation and MAP kinase activation in EGF induced enhancement of cell communication in human kidney epithelial cells.
    Cell adhesion and communication, 1998, Volume: 5, Issue:6

    Topics: Antibodies; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Communication; Cell Line; Connexin 43; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Gap Junctions; Humans; Kidney; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Precipitin Tests; Tetradecanoylphorbol Acetate; Time Factors

1998
Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts.
    The Journal of biological chemistry, 1999, Aug-27, Volume: 274, Issue:35

    Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromatin; Epidermal Growth Factor; Fluorescent Antibody Technique; Gene Expression Regulation; Genes, fos; Genes, myc; Genes, ras; Histones; Mice; Mitogens; Okadaic Acid; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins; Tetradecanoylphorbol Acetate; Transformation, Genetic

1999
Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells.
    The Journal of cell biology, 1999, Sep-06, Volume: 146, Issue:5

    Topics: Actins; Antigens, Surface; Carbazoles; Carcinoma, Squamous Cell; Cell Membrane; Cell Size; Chemotaxis; Desmosomes; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Indoles; Integrin alpha6beta4; Integrins; Keratins; Laminin; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Pseudopodia; Signal Transduction; Tumor Cells, Cultured

1999
Serine phosphorylation and negative regulation of Stat3 by JNK.
    The Journal of biological chemistry, 1999, Oct-22, Volume: 274, Issue:43

    Topics: Amino Acid Substitution; Animals; COS Cells; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Gene Expression Regulation; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Point Mutation; Pyridines; Recombinant Fusion Proteins; Serine; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Transfection; Ultraviolet Rays

1999
Phosphorylation and regulation of Raf by Akt (protein kinase B).
    Science (New York, N.Y.), 1999, Nov-26, Volume: 286, Issue:5445

    Topics: Cell Division; Cell Line; Chromones; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Humans; MAP Kinase Signaling System; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; ras Proteins; Recombinant Fusion Proteins; Signal Transduction; Somatomedins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Regulation of STAT3 by direct binding to the Rac1 GTPase.
    Science (New York, N.Y.), 2000, Oct-06, Volume: 290, Issue:5489

    Topics: Amino Acid Substitution; Animals; Cell Line; Chlorocebus aethiops; COS Cells; DNA-Binding Proteins; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation; Genes, Reporter; Genetic Vectors; Guanine Nucleotide Exchange Factors; Humans; Janus Kinase 2; Mutation; Neoplasm Proteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; rac1 GTP-Binding Protein; Rats; Signal Transduction; STAT3 Transcription Factor; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Trans-Activators; Transfection; Two-Hybrid System Techniques

2000
Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes.
    Molecular endocrinology (Baltimore, Md.), 2000, Volume: 14, Issue:10

    Topics: 3T3 Cells; Adipocytes; Animals; Anisomycin; Cell Differentiation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Kinetics; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Tumor Necrosis Factor-alpha

2000
Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.
    The Journal of biological chemistry, 2001, Apr-20, Volume: 276, Issue:16

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Androstadienes; Animals; Cell Line; Cell Membrane; Chlorocebus aethiops; COS Cells; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Kinetics; MAP Kinase Signaling System; Mice; Phosphatidylinositol 3-Kinases; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; Ribosomal Protein S6 Kinases; Tetradecanoylphorbol Acetate; Wortmannin

2001
Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer.
    Molecular and cellular biochemistry, 2001, Volume: 218, Issue:1-2

    Topics: Animals; Antibodies, Monoclonal; Becaplermin; Breast Neoplasms; Cells, Cultured; Colforsin; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique; Humans; Immunoblotting; Mice; Microscopy, Confocal; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphoserine; Platelet-Derived Growth Factor; Prognosis; Proto-Oncogene Proteins c-sis; Receptor, ErbB-2; Transfection; Vanadates

2001
Induction of Akt phosphorylation in rat primary astrocytes by H2O2 occurs upstream of phosphatidylinositol 3-kinase: no evidence for oxidative inhibition of PTEN.
    Archives of biochemistry and biophysics, 2001, Feb-15, Volume: 386, Issue:2

    Topics: Acetylcysteine; Androstadienes; Animals; Antimycin A; Astrocytes; Blotting, Western; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Hydrogen Peroxide; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rotenone; Signal Transduction; Tumor Suppressor Proteins; Uncoupling Agents; Wortmannin

2001
14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.
    Molecular endocrinology (Baltimore, Md.), 2002, Volume: 16, Issue:3

    Topics: 14-3-3 Proteins; 3T3 Cells; Animals; Biological Transport; Cell Nucleus; COS Cells; Cytoplasm; Cytosol; Enzyme Inhibitors; Epidermal Growth Factor; Fluorescent Antibody Technique; Immunosorbent Techniques; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Mice; Microscopy, Confocal; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine 3-Monooxygenase

2002
Phosphorylation of glycogen synthase kinase-3beta at serine-9 by phospholipase Cgamma1 through protein kinase C in rat 3Y1 fibroblasts.
    Experimental & molecular medicine, 2002, Dec-31, Volume: 34, Issue:6

    Topics: Animals; Cyclin D1; Epidermal Growth Factor; Fibroblasts; Gene Expression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Mitogens; Phospholipase C gamma; Phosphorylation; Phosphoserine; Protein Kinase C; Rats; Signal Transduction; Type C Phospholipases

2002
Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling.
    The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Antibodies, Monoclonal; Antigens, CD; Carrier Proteins; Cytokine Receptor gp130; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Human Growth Hormone; Humans; Immunoblotting; Indoles; Janus Kinase 2; Maleimides; MAP Kinase Kinase 1; Membrane Glycoproteins; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptor, ErbB-2; Recombinant Fusion Proteins; Signal Transduction; Transfection; Ubiquitin-Protein Ligases

2003
Bombesin, lysophosphatidic acid, and epidermal growth factor rapidly stimulate focal adhesion kinase phosphorylation at Ser-910: requirement for ERK activation.
    The Journal of biological chemistry, 2003, Jun-20, Volume: 278, Issue:25

    Topics: 3T3 Cells; Animals; Base Sequence; Bombesin; DNA Primers; Enzyme Activation; Epidermal Growth Factor; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Kinetics; Lysophospholipids; MAP Kinase Signaling System; Mice; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphoserine; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Recombinant Fusion Proteins

2003
EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes.
    Journal of cellular physiology, 2003, Volume: 196, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; DNA; DNA-Binding Proteins; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Growth Hormone; Hepatocytes; Male; Milk Proteins; Mitogens; Phosphorylation; Phosphoserine; Phosphotyrosine; Prolactin; Protein Binding; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Pyrroles; Rats; Rats, Wistar; STAT5 Transcription Factor; Trans-Activators; Transforming Growth Factor alpha

2003
Thrombin and histamine stimulate endothelial nitric-oxide synthase phosphorylation at Ser1177 via an AMPK mediated pathway independent of PI3K-Akt.
    FEBS letters, 2004, Aug-27, Volume: 573, Issue:1-3

    Topics: AMP-Activated Protein Kinases; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Endothelial Cells; Enzyme Activation; Epidermal Growth Factor; Histamine; Humans; Multienzyme Complexes; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Thrombin

2004
Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL.
    The Biochemical journal, 2004, Dec-15, Volume: 384, Issue:Pt 3

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Androstadienes; Animals; Antibody Specificity; Benzamides; Cell Extracts; Cell Line; Contractile Proteins; Epidermal Growth Factor; Filamins; Humans; Immediate-Early Proteins; Insulin; Isoenzymes; Mice; Microfilament Proteins; Molecular Sequence Data; Molecular Weight; Muscle, Skeletal; Myoblasts; Myocardium; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rabbits; Signal Transduction; Sirolimus; Substrate Specificity; Wortmannin

2004
Phosphorylation of estrogen receptor alpha serine 167 is predictive of response to endocrine therapy and increases postrelapse survival in metastatic breast cancer.
    Breast cancer research : BCR, 2005, Volume: 7, Issue:5

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chlorocebus aethiops; COS Cells; Epidermal Growth Factor; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Metastasis; Phosphorylation; Phosphoserine; Prognosis; Receptor, ErbB-2; Receptors, Progesterone; Recombinant Proteins; Recurrence; Survival Analysis; Transfection

2005
Phosphorylation of JAK2 at serine 523: a negative regulator of JAK2 that is stimulated by growth hormone and epidermal growth factor.
    Molecular and cellular biology, 2006, Volume: 26, Issue:11

    Topics: 3T3 Cells; Alanine; Animals; Butadienes; Cells, Cultured; Chlorocebus aethiops; COS Cells; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Growth Hormone; Humans; Janus Kinase 2; MAP Kinase Kinase 1; Mass Spectrometry; Mice; Mutation; Nitriles; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Repressor Proteins; STAT5 Transcription Factor; Tetradecanoylphorbol Acetate

2006
Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells.
    Molecular biology of the cell, 2007, Volume: 18, Issue:8

    Topics: Amino Acid Substitution; Casein Kinase II; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; Focal Adhesions; Humans; Mutant Proteins; Myosin Heavy Chains; Nonmuscle Myosin Type IIA; Phosphorylation; Phosphoserine; Protein Binding; Protein Isoforms; Protein Transport; Pseudopodia; Solubility

2007
Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption.
    Molecular biology of the cell, 2007, Volume: 18, Issue:9

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Chlorocebus aethiops; COS Cells; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; ErbB Receptors; Hemidesmosomes; Humans; Integrin beta4; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Plectin; Protein Kinase C; Protein Structure, Tertiary; Protein Subunits

2007
14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase.
    Experimental cell research, 2007, Oct-01, Volume: 313, Issue:16

    Topics: 14-3-3 Proteins; Amino Acid Motifs; Amino Acid Sequence; Animals; Catalysis; Cell Division; Chlorocebus aethiops; COS Cells; Endopeptidases; Endosomal Sorting Complexes Required for Transport; Enzyme Activation; Epidermal Growth Factor; HeLa Cells; Humans; Mice; Molecular Sequence Data; Mutant Proteins; Phosphorylation; Phosphoserine; Protein Binding; Protein Transport; Subcellular Fractions; Substrate Specificity; Ubiquitin; Ubiquitin Thiolesterase

2007
p21 activated kinase 5 activates Raf-1 and targets it to mitochondria.
    Journal of cellular biochemistry, 2008, Sep-01, Volume: 105, Issue:1

    Topics: Cell Line; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Humans; Mitochondria; Mitogen-Activated Protein Kinases; p21-Activated Kinases; Phosphoserine; Protein Binding; Proto-Oncogene Proteins c-raf

2008
Cdk5 phosphorylates PLD2 to mediate EGF-dependent insulin secretion.
    Cellular signalling, 2008, Volume: 20, Issue:10

    Topics: Amino Acid Sequence; Animals; Cell Line; Cyclin-Dependent Kinase 5; Enzyme Activation; Epidermal Growth Factor; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Molecular Sequence Data; Phospholipase D; Phosphorylation; Phosphoserine; Protein Binding; Rats; Substrate Specificity

2008
JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin.
    Cellular signalling, 2008, Volume: 20, Issue:11

    Topics: Cell Line; Cell Movement; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Epithelium, Corneal; Focal Adhesion Protein-Tyrosine Kinases; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Models, Biological; Mutant Proteins; Paxillin; Phosphorylation; Phosphoserine; Phosphotyrosine

2008
Characterization of Ser338 phosphorylation for Raf-1 activation.
    The Journal of biological chemistry, 2008, Nov-14, Volume: 283, Issue:46

    Topics: Cell Line; Enzyme Activation; Epidermal Growth Factor; Humans; Mutation; p21-Activated Kinases; Phosphoserine; Protein Multimerization; Proto-Oncogene Proteins c-raf

2008
Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cell Proliferation; Cloning, Molecular; Dimerization; Drug Synergism; Epidermal Growth Factor; Humans; Immunoglobulin Fc Fragments; Ligands; Mice; Neuregulin-1; Phosphoserine; Protein Kinase Inhibitors; Protein Structure, Tertiary; Receptor, ErbB-2; Receptor, ErbB-3; Trastuzumab; Xenograft Model Antitumor Assays

2008
Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.
    Molecular & cellular proteomics : MCP, 2009, Volume: 8, Issue:9

    Topics: Blotting, Western; Cell Line; Chromatography, Liquid; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; MAP Kinase Signaling System; Mass Spectrometry; Mutant Proteins; Phosphorylation; Phosphoserine; Phosphothreonine; Structure-Activity Relationship; Time Factors

2009
Src kinase-mediated phosphorylation stabilizes inducible nitric-oxide synthase in normal cells and cancer cells.
    The Journal of biological chemistry, 2010, Jan-01, Volume: 285, Issue:1

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Enzyme Activation; Enzyme Stability; Epidermal Growth Factor; Epithelium; Half-Life; Humans; Lung; Mice; Mice, Inbred C57BL; Models, Biological; Neoplasms; Nitric Oxide Synthase Type II; Phosphorylation; Phosphoserine; Pneumonia; Protein Transport; src-Family Kinases

2010
EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin.
    Molecular cell, 2009, Nov-25, Volume: 36, Issue:4

    Topics: alpha Catenin; Amino Acid Sequence; beta Catenin; Binding Sites; Casein Kinase II; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Glioblastoma; Humans; Molecular Sequence Data; Neoplasm Invasiveness; Phosphorylation; Phosphoserine; Protein Binding; Transcriptional Activation

2009
EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase.
    Journal of cellular physiology, 2011, Volume: 226, Issue:9

    Topics: Animals; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Hepatocytes; Male; Mice; Models, Biological; NADPH Oxidases; Phosphorylation; Phosphoserine; rac1 GTP-Binding Protein; Rats; Rats, Wistar

2011
Critical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Animals; Cell Differentiation; Cell Lineage; Enzyme Activation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Homeodomain Proteins; Humans; Male; Motor Neurons; Neural Stem Cells; Phosphatidylinositol 3-Kinase; Phosphorylation; Phosphoserine; Protein Kinase C; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Messenger; Signal Transduction; Time Factors; Transcription Factors

2011
Chk1-mediated phosphorylation of receptor-associated late transducer at serine 250 increases its stability by stimulating its interaction with 14-3-3.
    Genes to cells : devoted to molecular & cellular mechanisms, 2013, Volume: 18, Issue:5

    Topics: 14-3-3 Proteins; Amino Acid Motifs; Animals; Checkpoint Kinase 1; Chlorocebus aethiops; COS Cells; Epidermal Growth Factor; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; Mutant Proteins; Mutation; Phosphorylation; Phosphoserine; Protein Binding; Protein Isoforms; Protein Kinases; Protein Stability; Protein Transport; Rats; Substrate Specificity

2013
Protein kinase CK2 phosphorylates and activates p21-activated kinase 1.
    Molecular biology of the cell, 2013, Volume: 24, Issue:18

    Topics: Animals; Biocatalysis; Blotting, Western; Casein Kinase II; Cell Line, Tumor; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; Humans; Male; Mass Spectrometry; Mice; Models, Biological; Mutation; p21-Activated Kinases; Phosphorylation; Phosphoserine; Prostate; Reproducibility of Results

2013
EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells.
    Cell death & disease, 2013, Oct-03, Volume: 4

    Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin-Dependent Kinase 5; Epidermal Growth Factor; ErbB Receptors; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Integrins; MAP Kinase Signaling System; Microtubules; Mitosis; Neoplasms; Phosphorylation; Phosphoserine; Polymerization; Spindle Apparatus

2013
C-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Sep-16, Volume: 111, Issue:37

    Topics: Animals; beta-Transducin Repeat-Containing Proteins; Cell Differentiation; Chickens; Chromatin; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Green Fluorescent Proteins; HEK293 Cells; Humans; MAP Kinase Signaling System; Mice; Mutation; Neurons; NIMA-Interacting Peptidylprolyl Isomerase; Nuclear Proteins; PC12 Cells; Peptides; Peptidylprolyl Isomerase; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Protein Binding; Protein Stability; Proteolysis; ras Proteins; Rats; Repressor Proteins

2014
Serine-727 phosphorylation activates hypothalamic STAT-3 independently from tyrosine-705 phosphorylation.
    Molecular endocrinology (Baltimore, Md.), 2015, Volume: 29, Issue:3

    Topics: Animals; Bradykinin; Cell Line; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Genes, Reporter; Humans; Hypothalamus; Interferon-gamma; Ligands; Melanocyte-Stimulating Hormones; Mice; Neurons; Neuropeptide Y; Phosphorylation; Phosphoserine; Phosphotyrosine; Promoter Regions, Genetic; Receptors, Cytokine; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Thyrotropin-Releasing Hormone; Transcriptional Activation

2015
Type II cGMP-dependent protein kinase directly inhibits HER2 activation of gastric cancer cells.
    Molecular medicine reports, 2016, Volume: 13, Issue:2

    Topics: Cell Line, Tumor; Cyclic GMP-Dependent Protein Kinase Type II; Epidermal Growth Factor; Humans; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Binding; Receptor, ErbB-2; Stomach Neoplasms

2016
EGFR phosphorylates FAM129B to promote Ras activation.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, Jan-19, Volume: 113, Issue:3

    Topics: Amino Acid Sequence; Antibody Specificity; beta Catenin; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Models, Biological; Molecular Sequence Data; Neoplasm Invasiveness; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Binding; Proto-Oncogene Proteins p21(ras); ras GTPase-Activating Proteins; Transcriptional Activation

2016
EphA2 is a key effector of the MEK/ERK/RSK pathway regulating glioblastoma cell proliferation.
    Cellular signalling, 2016, Volume: 28, Issue:8

    Topics: Brain Neoplasms; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Factor; Glioblastoma; Humans; MAP Kinase Signaling System; Phosphorylation; Phosphoserine; Receptor, EphA2; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction

2016
PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis.
    Nature communications, 2016, 08-03, Volume: 7

    Topics: Animals; beta Catenin; Brain Neoplasms; Carcinogenesis; cdc25 Phosphatases; Cell Line, Tumor; Cell Nucleus; Epidermal Growth Factor; Glioblastoma; Glycolysis; Humans; Mice; Phosphorylation; Phosphoserine; Phosphotyrosine; Prognosis; Protein Binding; Proto-Oncogene Proteins c-myc; Pyruvate Kinase; src-Family Kinases; Transcriptional Activation

2016
Stress-activated MAPKs and CRM1 regulate the subcellular localization of Net1A to control cell motility and invasion.
    Journal of cell science, 2018, 02-01, Volume: 131, Issue:3

    Topics: Cell Movement; Cytosol; Epidermal Growth Factor; Exportin 1 Protein; Extracellular Matrix; Glutamic Acid; Humans; Karyopherins; MCF-7 Cells; Mitogen-Activated Protein Kinases; Mutation; Oncogene Proteins; Phosphorylation; Phosphoserine; Podosomes; Protein Transport; Receptors, Cytoplasmic and Nuclear; rhoA GTP-Binding Protein; Signal Transduction; Stress, Physiological; Tumor Necrosis Factor-alpha

2018
The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance.
    Nature communications, 2018, 11-09, Volume: 9, Issue:1

    Topics: Adenylate Kinase; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Progression; Drug Resistance, Neoplasm; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Glycolysis; Human Umbilical Vein Endothelial Cells; Humans; Mice; Neovascularization, Pathologic; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins c-akt; S-Phase Kinase-Associated Proteins; Signal Transduction; Stress, Physiological; Ubiquitination

2018