phosphorylcholine has been researched along with sphingosine 1-phosphate in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (37.25) | 18.2507 |
| 2000's | 26 (50.98) | 29.6817 |
| 2010's | 6 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Farach-Carson, MC; Karin, NJ; Liu, R | 1 |
| Brooker, G; Buckley, NE; Carlson, RO; Desai, NN; Mattie, ME; Olivera, A; Seki, T; Spiegel, S | 1 |
| Milstien, S; Spiegel, S | 1 |
| Jakobs, KH; Laser, KT; Meyer Zu Heringdorf, D; Van Koppen, CJ; Zhang, C | 1 |
| Berger, A; Bittman, R; Schmidt, RR; Spiegel, S | 1 |
| Brandts, BK; Bünemann, M; Desiderio, DM; Liliom, K; Miller, D; Pott, L; Sun, G; Tigyi, G; Tseng, JL | 1 |
| Himmel, HM; Jakobs, KH; Meyer zu Heringdrof, D; van Koppen, CJ; Windorfer, B | 1 |
| Anderson, WH; Chung, T; Crilly, KS; Kiss, Z; Mukherjee, JJ | 1 |
| Kondo, Y; Ohwada, S; Okajima, F; Yamada, T | 1 |
| Kiss, Z; Mukherjee, JJ | 1 |
| Hrelia, S; Orlati, S; Rugolo, M | 1 |
| Kaida, T; Kozawa, O; Suzuki, A; Tokuda, H; Uematsu, T | 1 |
| Crilly, KS; Kiss, Z; Tomono, M | 1 |
| Himmel, HM; Jakobs, KH; Meyer zu Heringdorf, D; Ravens, U; van Koppen, CJ; Windorfer, B | 1 |
| Chen, PF; Chin, TY; Chueh, SH | 1 |
| Hrelia, S; Orlati, S; Porcelli, AM; Rugolo, M | 1 |
| Gonda, K; Okamoto, H; Shigematsu, H; Takuwa, N; Takuwa, Y; Yatomi, Y | 1 |
| Barańska, J; Bobeszko, M; Dygas, A; Sidorko, M | 1 |
| Barańska, J; Wójcik, M | 1 |
| Hanske, J; Jakobs, KH; Lümmen, G; Meyer zu Heringdorf, D; Rümenapp, U; Virchow, S | 1 |
| Boguslawski, G; English, D; Harvey, KA; Kovala, AT; Lyons, D | 1 |
| Kon, J; Murata, N; Okajima, F; Sato, K; Tomura, H | 1 |
| Bischoff, A; Czyborra, P; Fetscher, C; Jakobs, KH; Meyer Zu Heringdorf, D; Michel, MC | 1 |
| Bischoff, A; Czyborra, P; Jakobs, KH; Meyer Zu Heringdorf, D; Michel, MC | 1 |
| Alemany, R; Jakobs, KH; Kuchar, I; Lass, H; Lipinski, M; Meyer zu Heringdorf, D; Rümenapp, U | 1 |
| Lynch, KR; Macdonald, TL | 1 |
| Baudhuin, LM; Hong, G; Mok, SC; Morrison, BH; Schwartz, BM; Wu, W; Xiao, YJ; Xu, Y | 1 |
| Karin, NJ; Lyons, JM | 1 |
| Han, SS; Lee, M | 1 |
| Himmel, HM; Jakobs, KH; Meyer zu Heringdorf, D | 1 |
| Brailoiu, E; Dun, NJ; Patel, S | 1 |
| Arikawa, K; Kitayama, J; Nagawa, H; Sugimoto, N; Takehara, K; Takuwa, N; Takuwa, Y; Yamaguchi, H | 1 |
| Aoki, J; Bandle, RW; Clair, T; Koh, E; Liotta, LA; Mills, GB; Nam, SW; Ptaszynska, MM; Schiffmann, E; Stracke, ML | 1 |
| Ikari, S; Matsuda, H; Ochi, S; Oda, M; Sakurai, J | 1 |
| Fetscher, C; Hedemann, J; Michel, MC | 1 |
| Anand-Apte, B; Cristina, K; Ebrahem, Q; Jiang, Y; Kim, KS; Lum, H; Qiao, J; Ren, J; Taylor, KL; Tipps, R; Xiao, YJ; Xu, Y | 1 |
| Alewijnse, AE; Michel, MC | 1 |
| Mathieson, FA; Nixon, GF | 1 |
| Afrasiabi, E; Blom, T; Ekokoski, E; Törnquist, K; Tuominen, RK | 1 |
| Bischoff, A; Czyborra, C; Michel, MC | 1 |
| Hemmings, DG | 1 |
| Brahmbhatt, VV; Ford, DA; Frank, EC; Hsu, FF; Kao, JL | 1 |
| Alewijnse, AE; Jongsma, M; Michel, MC; Mulders, AC; Peters, SL | 1 |
| Li, Y; Michel, MC; Mulders, AC; Nau, S | 1 |
| Ahn, DS; Choi, SK; Lee, YH | 1 |
| Hunter, I; Mathieson, FA; Nixon, GF; Wirrig, C | 1 |
| Chun, J; Echtermeyer, F; Herrgott, I; Herzog, C; Hildebrand, R; Johanning, K; Larmann, J; Levkau, B; Mersmann, J; Müller, FU; Schmitz, M; Theilmeier, G; Winterhalter, M | 1 |
| Eriksson, JE; Fazeli, E; Goto, H; Hyder, CL; Imanishi, SY; Inagaki, M; Isoniemi, KO; Kemppainen, K; Törnquist, K | 1 |
| El-Najjar, N; Liebisch, G; Orsó, E; Schmitz, G; Wallner, S | 1 |
| Gao, D; Guan, J; Guo, Y; Jiang, Y; Liu, H; Wang, Y; Xie, W; Yang, T | 1 |
| Georgiev, G; Maslenkova, L; Momchilova, A; Pankov, R; Skrobanska, R; Stoyanova, T; Tsonchev, Z; Tzoneva, R; Uzunova, V | 1 |
5 review(s) available for phosphorylcholine and sphingosine 1-phosphate
| Article | Year |
|---|---|
Sphingolipid metabolites: members of a new class of lipid second messengers.
Topics: Animals; Calcium; Cyclic AMP; Growth Substances; Humans; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Mice; Mitosis; Models, Biological; Phosphatidic Acids; Phosphorylcholine; Protein Kinase C; Rats; Second Messenger Systems; Sphingolipidoses; Sphingolipids; Sphingosine; Transcription Factor AP-1 | 1995 |
Structure activity relationships of lysophospholipid mediators.
Topics: Drug Industry; Lysophospholipids; Phosphorylcholine; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Signal Transduction; Sphingosine | 2001 |
Sphingosylphosphorylcholine-biological functions and mechanisms of action.
Topics: Animals; Calcium Signaling; GTP-Binding Proteins; Humans; Lysophospholipids; Phosphorylcholine; Receptors, Cell Surface; Signal Transduction; Sphingosine | 2002 |
Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine.
Topics: Animals; Blood Vessels; Calcium; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lysophospholipids; Phosphorylcholine; Prostaglandin-Endoperoxide Synthases; Receptors, G-Protein-Coupled; Signal Transduction; Sphingosine; Vasoconstriction; Vasodilation | 2006 |
Vascular effects of sphingolipids.
Topics: Humans; Lysophospholipids; Phosphorylcholine; Sphingolipids; Sphingosine; Vasoconstriction; Vasodilation | 2007 |
46 other study(ies) available for phosphorylcholine and sphingosine 1-phosphate
| Article | Year |
|---|---|
Effects of sphingosine derivatives on MC3T3-E1 pre-osteoblasts: psychosine elicits release of calcium from intracellualr stores.
Topics: 3T3 Cells; Animals; Calcium; Fluorescent Dyes; Fura-2; Kinetics; Lysophospholipids; Mice; Osteoblasts; Phosphorylation; Phosphorylcholine; Psychosine; Sphingosine; Structure-Activity Relationship | 1995 |
Signaling pathways for sphingosylphosphorylcholine-mediated mitogenesis in Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Calcium; Cell Division; Cyclic AMP; Growth Substances; Lysophospholipids; Mice; Phosphatidylinositols; Phosphorylcholine; Protein Kinase C; Signal Transduction; Sphingosine | 1993 |
A distinct G(i) protein-coupled receptor for sphingosylphosphorylcholine in human leukemia HL-60 cells and human neutrophils.
Topics: Calcium; Cell Division; GTP-Binding Proteins; HL-60 Cells; Humans; Lysophospholipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Phosphorylcholine; Sphingosine; Superoxides; Type C Phospholipases | 1996 |
Structural requirements of sphingosylphosphocholine and sphingosine-1-phosphate for stimulation of activator protein-1 activity.
Topics: 3T3 Cells; Animals; Base Sequence; Binding Sites; Cell Division; Consensus Sequence; DNA; Lysophospholipids; Mice; Molecular Sequence Data; Phosphorylcholine; Sphingolipids; Sphingosine; Structure-Activity Relationship; Transcription Factor AP-1 | 1996 |
A novel membrane receptor with high affinity for lysosphingomyelin and sphingosine 1-phosphate in atrial myocytes.
Topics: Animals; Electrophysiology; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Guinea Pigs; Heart Atria; Lysophospholipids; Magnetic Resonance Spectroscopy; Models, Molecular; Pertussis Toxin; Phosphorylcholine; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Muscarinic; Spectrometry, Mass, Fast Atom Bombardment; Sphingosine; Stereoisomerism; Structure-Activity Relationship; Virulence Factors, Bordetella | 1996 |
Calcium signalling by G protein-coupled sphingolipid receptors in bovine aortic endothelial cells.
Topics: Adenosine Triphosphate; Animals; Aorta; Calcium; Cattle; Cells, Cultured; Endothelium, Vascular; GTP-Binding Proteins; Lysophospholipids; Pertussis Toxin; Phospholipases; Phosphorylcholine; Receptors, Cell Surface; Signal Transduction; Sphingolipids; Sphingosine; Virulence Factors, Bordetella | 1996 |
ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3'-kinase through an extracellular site. Synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate.
Topics: 3T3 Cells; Adenosine Triphosphate; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; DNA; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Harvey murine sarcoma virus; Immunosuppressive Agents; Insulin; Kinetics; Lysophospholipids; Mice; Models, Biological; Phosphatidylinositol 3-Kinases; Phospholipases A; Phosphorylcholine; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Protein Serine-Threonine Kinases; Recombinant Proteins; Ribosomal Protein S6 Kinases; Sirolimus; Sphingosine; Thymidine; Transfection; Wortmannin | 1997 |
Growth inhibition of human pancreatic cancer cells by sphingosylphosphorylcholine and influence of culture conditions.
Topics: 3T3 Cells; Animals; Cattle; Cell Culture Techniques; Cell Cycle; Cell Division; Ceramides; DNA; Humans; Lysophospholipids; Mice; Nucleic Acid Synthesis Inhibitors; Pancreatic Neoplasms; Phosphorylcholine; Serum Albumin; Sphingosine; Tumor Cells, Cultured | 1997 |
Phosphocholine and sphingosine-1-phosphate synergistically stimulate DNA synthesis by a MAP kinase-dependent mechanism.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA; Drug Synergism; Epidermis; Ethanolamine; Ethanolamines; Lysophospholipids; Mice; Mitogens; Phosphorylcholine; Sphingosine | 1997 |
Pertussis toxin- and PMA-insensitive calcium mobilization by sphingosine in CFPAC-1 cells: evidence for a phosphatidic acid-dependent mechanism.
Topics: Adenosine Triphosphate; Arachidonic Acid; Calcium; Cell Line; Humans; Inositol Phosphates; Lysophospholipids; Pertussis Toxin; Phosphatidic Acids; Phosphorylcholine; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1997 |
Tumor necrosis factor-alpha autoregulates interleukin-6 synthesis via activation of protein kinase C. Function of sphingosine 1-phosphate and phosphatidylcholine-specific phospholipase C.
Topics: 3T3 Cells; Animals; Bridged-Ring Compounds; Choline; Diglycerides; Enzyme Activation; Homeostasis; Inositol Phosphates; Interleukin-6; Kinetics; Lysophospholipids; Mice; Norbornanes; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Phosphorylcholine; Protein Kinase C; Sphingosine; Thiocarbamates; Thiones; Tumor Necrosis Factor-alpha; Type C Phospholipases | 1997 |
The choline kinase inhibitor hemicholinium-3 can inhibit mitogen-induced DNA synthesis independent of its effect on phosphocholine formation.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Choline Kinase; DNA; Drug Interactions; Enzyme Inhibitors; Fibroblast Growth Factors; Hemicholinium 3; Insulin; Kinetics; Lysophospholipids; Mice; Mitogens; Phosphorylcholine; Sphingosine | 1998 |
Guanine nucleotide-sensitive inhibition of L-type Ca2+ current by lysosphingolipids in RINm5F insulinoma cells.
Topics: Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Guanine Nucleotides; Humans; Insulinoma; Lysophospholipids; Phosphorylcholine; Potassium Chloride; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Sphingosine; Tumor Cells, Cultured | 1998 |
Ca2+ signaling induced by sphingosylphosphorylcholine and sphingosine 1-phosphate via distinct mechanisms in rat glomerular mesangial cells.
Topics: Animals; Arachidonic Acid; Calcium; Glomerular Mesangium; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Male; Manganese; Phospholipases A; Phospholipases A2; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Sphingosine | 1998 |
Sphingosylphosphorylcholine and sphingosine-1-phosphate mobilize cytosolic calcium through different mechanisms in human airway epithelial cells.
Topics: Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Epithelial Cells; GTP-Binding Proteins; Histamine; Humans; Inositol Phosphates; Lysophospholipids; Magnesium; Nasal Cavity; Palmitic Acid; Pertussis Toxin; Phosphatidic Acids; Phosphorylcholine; Sphingosine; Staurosporine; Thapsigargin; Time Factors; Virulence Factors, Bordetella | 1998 |
EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; Cyclic AMP; DNA-Binding Proteins; Dose-Response Relationship, Drug; Humans; I-kappa B Proteins; Immediate-Early Proteins; Inositol Phosphates; Lysophospholipids; NF-KappaB Inhibitor alpha; Phosphorylcholine; Proprotein Convertases; Protein Kinase C; ras Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Serine Endopeptidases; Signal Transduction; Sphingosine | 1999 |
Exogenous sphingosine 1-phosphate and sphingosylphosphorylcholine do not stimulate phospholipase D in C6 glioma cells.
Topics: Brain Neoplasms; Enzyme Activation; Glioma; Lysophospholipids; Phospholipase D; Phosphorylcholine; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Sphingosine, sphingosylphosphorylcholine and sphingosine 1-phosphate modulate phosphatidylserine homeostasis in glioma C6 cells.
Topics: Brain Neoplasms; Glioma; Homeostasis; Lysophospholipids; Phosphorylcholine; Sphingosine; Tumor Cells, Cultured | 1999 |
Sphingolipid receptor signaling and function in human bladder carcinoma cells: inhibition of LPA- but enhancement of thrombin-stimulated cell motility.
Topics: Actins; Calcium; Carcinoma; Cell Division; Cell Movement; Cyclic AMP; GTP-Binding Proteins; Humans; Lysophospholipids; Phospholipase D; Phosphorylcholine; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sphingolipids; Sphingosine; Thrombin; Tumor Cells, Cultured; Type C Phospholipases; Urinary Bladder Neoplasms | 2000 |
Sphingosylphosphorylcholine induces endothelial cell migration and morphogenesis.
Topics: Animals; Aorta; Cattle; Cell Differentiation; Cell Size; Chemotaxis; Down-Regulation; Endothelial Growth Factors; Endothelium, Vascular; Humans; Immediate-Early Proteins; Lymphokines; Lysophospholipids; Neovascularization, Physiologic; Phosphoric Monoester Hydrolases; Phosphorylcholine; Protein Kinase Inhibitors; Protein Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; rho GTP-Binding Proteins; RNA, Messenger; Sphingosine; Suramin; Time Factors; Umbilical Cord; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Virulence Factors, Bordetella | 2000 |
Quantitative measurement of sphingosine 1-phosphate by radioreceptor-binding assay.
Topics: Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Immediate-Early Proteins; Inhibitory Concentration 50; Kinetics; Lysophospholipids; Male; Phosphorylcholine; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Sphingosine; Tissue Distribution; U937 Cells | 2000 |
Sphingosine-1-phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitro.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; In Vitro Techniques; Indomethacin; Lysophospholipids; Male; Mesenteric Arteries; Nitrendipine; Nitroarginine; Pertussis Toxin; Phosphorylcholine; Psychosine; Rats; Rats, Wistar; Renal Artery; Sphingosine; Vasoconstriction; Vasodilator Agents; Virulence Factors, Bordetella | 2000 |
Sphingosine-1-phosphate reduces rat renal and mesenteric blood flow in vivo in a pertussis toxin-sensitive manner.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Kidney; Lysophospholipids; Male; Mesentery; Pertussis Toxin; Phosphorylcholine; Psychosine; Rats; Rats, Wistar; Renal Circulation; Sphingosine; Splanchnic Circulation; Virulence Factors, Bordetella | 2000 |
Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors.
Topics: Calcium Signaling; Carbachol; Cell Line; Cholinergic Agonists; DNA-Binding Proteins; GTP-Binding Proteins; Humans; I-kappa B Proteins; Immediate-Early Proteins; Lysophospholipids; NF-KappaB Inhibitor alpha; Phosphorylcholine; Phosphotransferases (Alcohol Group Acceptor); Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Sphingosine; Type C Phospholipases | 2001 |
Lysophospholipids increase interleukin-8 expression in ovarian cancer cells.
Topics: Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Lysophospholipids; Ovarian Neoplasms; Phosphorylcholine; RNA, Messenger; Sphingosine; Tumor Cells, Cultured; Up-Regulation | 2001 |
A role for G protein-coupled lysophospholipid receptors in sphingolipid-induced Ca2+ signaling in MC3T3-E1 osteoblastic cells.
Topics: 3T3 Cells; Animals; Base Sequence; Calcium Signaling; DNA, Complementary; GTP-Binding Proteins; Immediate-Early Proteins; Ion Channel Gating; Lysophospholipids; Mice; Molecular Sequence Data; Osteoblasts; Phosphorylcholine; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; RNA, Messenger; Sphingolipids; Sphingosine | 2001 |
Choline phosphate potentiates sphingosine-1-phosphate-induced Raf-1 kinase activation dependent of Ras--phosphatidylinositol-3-kinase pathway.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Drug Synergism; Enzyme Activation; Hydrogen Peroxide; Kinetics; Lysophospholipids; Mice; Phosphatidylinositol 3-Kinases; Phosphorylcholine; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Signal Transduction; Sphingosine | 2002 |
Modulation of spontaneous transmitter release from the frog neuromuscular junction by interacting intracellular Ca(2+) stores: critical role for nicotinic acid-adenine dinucleotide phosphate (NAADP).
Topics: Animals; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Electrophysiology; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Muscles; NADP; Neuromuscular Junction; Neurotransmitter Agents; Phosphorylcholine; Rana pipiens; Sphingosine; Thapsigargin; Wound Healing | 2003 |
Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity.
Topics: Adenoviridae; Animals; Blotting, Northern; Blotting, Western; Calcium; Cell Movement; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genetic Vectors; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Ligands; Lysophospholipids; Melanoma, Experimental; Mice; Neoplasm Invasiveness; Phosphorylcholine; Plasmids; Protein Isoforms; Pyrazoles; Pyridines; rac GTP-Binding Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysosphingolipid; rhoA GTP-Binding Protein; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Temperature; Time Factors | 2003 |
Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate.
Topics: 3T3 Cells; Animals; Catalysis; Cell Movement; Chlorocebus aethiops; COS Cells; Glucose-6-Phosphate Isomerase; Glycoproteins; Hydrolysis; Lysophospholipids; Mice; Multienzyme Complexes; Phosphodiesterase I; Phosphoric Diester Hydrolases; Phosphorylcholine; Pyrophosphatases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; rho GTP-Binding Proteins; Sphingosine | 2003 |
Clostridium perfringens alpha-toxin activates the sphingomyelin metabolism system in sheep erythrocytes.
Topics: 4-Aminobenzoic Acid; ADP Ribose Transferases; Amidohydrolases; Animals; Bacterial Toxins; Botulinum Toxins; Calcium-Binding Proteins; Ceramidases; Chromatography, Thin Layer; Diglycerides; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Erythrocytes; Ethanolamines; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hemolysis; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Oleic Acids; para-Aminobenzoates; Pertussis Toxin; Phosphatidylcholines; Phosphorylcholine; Phosphotransferases (Alcohol Group Acceptor); Rabbits; Sheep; Sphingomyelins; Sphingosine; Time Factors; Toxins, Biological; Type C Phospholipases | 2004 |
Comparison of noradrenaline and lysosphingolipid-induced vasoconstriction in mouse and rat small mesenteric arteries.
Topics: Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Lysophospholipids; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Norepinephrine; Phosphorylcholine; Potassium Chloride; Rats; Rats, Wistar; Sphingolipids; Sphingosine; Vasoconstrictor Agents | 2004 |
GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine.
Topics: Animals; Antibodies; Cell Division; Cell Movement; Cell Survival; Cells, Cultured; Chick Embryo; Endothelial Cells; Enzyme Activation; Gene Expression; Humans; Hydrogen-Ion Concentration; Lysophospholipids; Neovascularization, Physiologic; Oncogene Protein v-akt; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphorylcholine; Receptors, G-Protein-Coupled; Receptors, Vascular Endothelial Growth Factor; RNA, Small Interfering; Sphingosine; Umbilical Veins; Vascular Endothelial Growth Factor A | 2005 |
Sphingosine-1-phosphate and sphingosylphosphorylcholine: two of a kind?
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Lysophospholipids; Male; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Sphingosine | 2006 |
Sphingolipids differentially regulate mitogen-activated protein kinases and intracellular Ca2+ in vascular smooth muscle: effects on CREB activation.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Arteries; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Lysophospholipids; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Sphingolipids; Sphingosine | 2006 |
Sphingosylphosphorylcholine enhances calcium entry in thyroid FRO cells by a mechanism dependent on protein kinase C.
Topics: Boron Compounds; Calcium; Calcium Signaling; Cells, Cultured; Gadolinium; Gene Expression Regulation; Humans; Lysophospholipids; Phosphorylcholine; Protein Isoforms; Protein Kinase C; Protein Transport; Receptors, G-Protein-Coupled; RNA, Messenger; Sphingosine; Thapsigargin; Thymidine; Thyroid Gland; Tritium | 2006 |
Indomethacin differentiates the renal effects of sphingosine-1-phosphate and sphingosylphosphorylcholine.
Topics: Animals; Blood Pressure; Diuresis; Heart Rate; Indomethacin; Kidney; Lysophospholipids; Male; Natriuresis; Neuropeptide Y; Pertussis Toxin; Phosphorylcholine; Rats; Rats, Wistar; Renal Circulation; Sphingosine | 2006 |
Novel carbonyl and nitrile products from reactive chlorinating species attack of lysosphingolipid.
Topics: Aldehydes; Chlorine; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Lipoproteins, HDL; Lysophospholipids; Peroxidase; Phosphorylcholine; Sphingosine | 2007 |
Effects of sphingosine-1-phosphate and sphingosylphosphorylcholine on intracellular Ca2+ and cell death in prostate cancer cell lines.
Topics: Apoptosis; Calcium; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Intracellular Fluid; Lysophospholipids; Male; Phosphorylcholine; Prostatic Neoplasms; Sphingosine | 2007 |
Comparison of contractile mechanisms of sphingosylphosphorylcholine and sphingosine-1-phosphate in rabbit coronary artery.
Topics: Animals; Calcium; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Lysophospholipids; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Phosphorylation; Phosphorylcholine; Rabbits; rho-Associated Kinases; Sarcoplasmic Reticulum; Signal Transduction; Sphingosine | 2009 |
Sphingosylphosphorylcholine is a proinflammatory mediator in cerebral arteries.
Topics: Animals; Blood Platelets; Blotting, Western; Cells, Cultured; Cerebral Arteries; Chemokine CCL2; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Inflammation; Inflammation Mediators; Lysophospholipids; Male; Muscle, Smooth, Vascular; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Sphingosine; Subarachnoid Hemorrhage; Transcription Factors; Up-Regulation; Vasospasm, Intracranial | 2011 |
Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury.
Topics: Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart; Humans; Lipoproteins, HDL; Lysophospholipids; Mice; Mice, Inbred C57BL; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Phosphorylcholine; Rats; Sphingosine | 2010 |
Sphingolipids inhibit vimentin-dependent cell migration.
Topics: Animals; Cell Line; Cell Line, Tumor; Cell Movement; Fibroblasts; Humans; Lysophospholipids; Mice; Phosphorylation; Phosphorylcholine; Receptors, Lysosphingolipid; rho-Associated Kinases; Signal Transduction; Sphingolipids; Sphingosine; Sphingosine-1-Phosphate Receptors; Vimentin | 2015 |
Increased Levels of Sphingosylphosphorylcholine (SPC) in Plasma of Metabolic Syndrome Patients.
Topics: Biomarkers; Female; Humans; Inflammation; Lipids; Lysophospholipids; Male; Metabolic Syndrome; Middle Aged; Obesity; Phosphorylcholine; Risk Factors; Sphingosine; Tetraspanin 30 | 2015 |
Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line.
Topics: Antineoplastic Agents; Biological Products; Cell Survival; Chromatography, High Pressure Liquid; Colon; Colonic Neoplasms; HCT116 Cells; Humans; Lactones; Lysophosphatidylcholines; Lysophospholipids; Metabolic Networks and Pathways; Metabolomics; Phosphatidylcholines; Phosphorylcholine; Sphingosine; Tandem Mass Spectrometry | 2016 |
Dimethylsphingosine and miltefosine induce apoptosis in lung adenocarcinoma A549 cells in a synergistic manner.
Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Drug Synergism; Humans; Lysophospholipids; Phosphorylcholine; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Sphingosine | 2019 |