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phosphoribosyl pyrophosphate and uridine triphosphate

phosphoribosyl pyrophosphate has been researched along with uridine triphosphate in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19909 (42.86)18.7374
1990's8 (38.10)18.2507
2000's4 (19.05)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, TL; Erlichman, C1
Coit, D; Colofiore, J; Kelsen, D; Martin, DS; Sawyer, R1
Ropp, PA; Traut, TW1
Laurensse, EJ; Peters, GJ; Pinedo, HM; van Groeningen, CJ1
Klubes, P; Parker, WB1
Balis, ME; Colofiore, JR; Martin, DS; Sawyer, RC1
Elödi, P; Matyasi, G; Szondy, Z1
Christopherson, RI; Lyons, SD1
Cortes, P; Levin, NW; Schoenberger, AM; Venkatachalam, KK; Verghese, CP1
Epstein, J; Harkrader, RJ; Jackson, RC; Ross, DA1
Aussedat, J; Rossi, A; Verdetti, J1
Kato, H; Patterson, D; Rumsby, PC; Waldren, CA1
Cortes, P; Dumler, F; Levin, NW; Venkatachalam, KK1
Evans, DR; Guy, HI; Liu, X1
Fujio, T; Maruyama, A1
Banerjei, LC; Davidson, JN1
Evans, DR; Guy, HI1
Collins, MA; Dahlstrand, EN; Earp, HS; Evans, DR; Graves, LM; Guy, HI; Huang, M; Kozlowski, P; Lazarowski, E; Pope, RM1
Evans, DR; Guy, HI; Sigoillot, FD1
Davidson, JN; Haubner, A; Ream, A; Simmons, AJ; Simmons, CQ1
Balestri, F; Barsotti, C; Camici, M; Ipata, PL; Lutzemberger, L1

Reviews

1 review(s) available for phosphoribosyl pyrophosphate and uridine triphosphate

ArticleYear
Effect of diabetes mellitus on renal metabolism.
    Mineral and electrolyte metabolism, 1983, Volume: 9, Issue:4-6

    Topics: Animals; Basement Membrane; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucose; Glycogen; Kidney; Kidney Cortex; Kidney Glomerulus; Phosphoribosyl Pyrophosphate; Rats; RNA; Uridine Triphosphate

1983

Trials

1 trial(s) available for phosphoribosyl pyrophosphate and uridine triphosphate

ArticleYear
A phase II trial of biochemical modulation using N-phosphonacetyl-L-aspartate, high-dose methotrexate, high-dose 5-fluorouracil, and leucovorin in patients with adenocarcinoma of unknown primary site.
    Cancer, 1992, Oct-01, Volume: 70, Issue:7

    Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Drug Evaluation; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasms, Unknown Primary; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate; Uridine Triphosphate

1992

Other Studies

19 other study(ies) available for phosphoribosyl pyrophosphate and uridine triphosphate

ArticleYear
Biochemical modulation of 5-fluorouracil with or without leucovorin by a low dose of brequinar in MGH-U1 cells.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Cell Survival; Cytidine Triphosphate; Deoxyuracil Nucleotides; Dose-Response Relationship, Drug; Drug Interactions; Fluorodeoxyuridylate; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Leucovorin; Phosphoribosyl Pyrophosphate; Thymidylate Synthase; Tumor Cells, Cultured; Uridine Triphosphate

1992
Allosteric regulation of purine nucleoside phosphorylase.
    Archives of biochemistry and biophysics, 1991, Aug-01, Volume: 288, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Animals; Cattle; Inosine; Kinetics; Mathematics; Models, Theoretical; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase; Spleen; Uridine Triphosphate

1991
A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa.
    Cancer, 1991, Nov-01, Volume: 68, Issue:9

    Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Colon; Colonic Neoplasms; Fluorodeoxyuridylate; Fluorouracil; Humans; Intestinal Mucosa; Middle Aged; Orotate Phosphoribosyltransferase; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Pyrimidine Phosphorylases; Rectal Neoplasms; Ribosemonophosphates; Uracil Nucleotides; Uridine Triphosphate

1991
Enhancement by uridine of the anabolism of 5-fluorouracil in mouse T-lymphoma (S-49) cells.
    Cancer research, 1985, Volume: 45, Issue:9

    Topics: Animals; Cell Survival; Cells, Cultured; DNA; Fluorouracil; Lymphoma; Mice; Phosphoribosyl Pyrophosphate; Protein Biosynthesis; Pyrimidines; RNA; T-Lymphocytes; Tritium; Uridine; Uridine Triphosphate

1985
Effect of uridine diphosphoglucose on levels of 5-phosphoribosyl pyrophosphate and uridine triphosphate in murine tissues.
    Pharmaceutical research, 1989, Volume: 6, Issue:10

    Topics: Animals; Chromatography, High Pressure Liquid; Liver; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental; Orotic Acid; Pentosephosphates; Phosphoribosyl Pyrophosphate; Uridine Diphosphate Glucose; Uridine Diphosphate Sugars; Uridine Triphosphate

1989
Effect of polyamines on the carbamoyl-phosphate synthase activity of CAD protein.
    Acta biochimica et biophysica Hungarica, 1989, Volume: 24, Issue:1-2

    Topics: Adenosine Triphosphate; Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Dihydroorotase; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Liver; Magnesium; Multienzyme Complexes; Phosphoribosyl Pyrophosphate; Polyamines; Rats; Uridine Triphosphate

1989
Regulation of hamster carbamoyl-phosphate synthase II by 5-phospho-alpha-D-ribosyl 1-diphosphate and uridine 5'-triphosphate.
    European journal of biochemistry, 1985, Mar-15, Volume: 147, Issue:3

    Topics: Adenosine Triphosphate; Allosteric Site; Animals; Binding, Competitive; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Catalysis; Chemical Phenomena; Chemistry; Cricetinae; Enzyme Activation; Kinetics; Ligases; Models, Chemical; Pentosephosphates; Phosphoribosyl Pyrophosphate; Substrate Specificity; Uracil Nucleotides; Uridine Triphosphate

1985
Phosphoribosylpyrophosphate bioavailability in diabetic rat renal cortex in vivo.
    The American journal of physiology, 1980, Volume: 238, Issue:4

    Topics: Adenine; Adenosine Triphosphate; Animals; Biological Availability; Diabetes Mellitus, Experimental; Infusions, Parenteral; Kidney Cortex; Male; Orotic Acid; Pentosephosphates; Phosphoribosyl Pyrophosphate; Rats; RNA; Uridine Triphosphate

1980
Biochemical approaches to enhancement of antitumor drug selectivity: selective protection of cells from 6-thioguanine and 6-mercaptopurine by adenosine.
    Cancer treatment reports, 1980, Volume: 64, Issue:12

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Count; Cell Line; Drug Interactions; Drug Resistance; Liver Neoplasms, Experimental; Mercaptopurine; Phosphoribosyl Pyrophosphate; Rats; Thioguanine; Uridine Diphosphate; Uridine Triphosphate

1980
[Effect of various precursors on the synthesis of adenine and uracil nucleotides in the rat heart (author's transl)].
    Journal de physiologie, 1980, Volume: 76, Issue:7

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Female; Isoproterenol; Myocardium; Phosphocreatine; Phosphoribosyl Pyrophosphate; Rats; Ribose; Uracil Nucleotides; Uridine; Uridine Triphosphate

1980
Effects of caffeine on pyrimidine biosynthesis and 5-phosphoribosyl 1-pyrophosphate metabolism in Chinese hamster cells.
    The Journal of biological chemistry, 1982, Oct-10, Volume: 257, Issue:19

    Topics: Animals; Caffeine; Cell Line; Cricetinae; Cricetulus; Cytidine Triphosphate; Female; Kinetics; Orotate Phosphoribosyltransferase; Orotic Acid; Ovary; Pentosephosphates; Phosphoribosyl Pyrophosphate; Pyrimidines; Uridine Triphosphate

1982
Identification of the regulatory domain of the mammalian multifunctional protein CAD by the construction of an Escherichia coli hamster hybrid carbamyl-phosphate synthetase.
    The Journal of biological chemistry, 1994, Nov-04, Volume: 269, Issue:44

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Amino Acid Sequence; Ammonia; Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cricetinae; Dihydroorotase; Enzyme Activation; Escherichia coli; Glutamine; Kinetics; Mesocricetus; Molecular Sequence Data; Multienzyme Complexes; Phosphoribosyl Pyrophosphate; Phosphorylation; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Uridine Triphosphate

1994
Enzymatic production of pyrimidine nucleotides using Corynebacterium ammoniagenes cells and recombinant Escherichia coli cells: enzymatic production of CDP-choline from orotic acid and choline chloride (Part I).
    Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:6

    Topics: Carbon-Nitrogen Ligases; Choline; Chromatography, High Pressure Liquid; Corynebacterium; Cytidine Diphosphate Choline; Cytidine Triphosphate; Escherichia coli; Gene Expression Regulation, Enzymologic; Ligases; Orotic Acid; Phosphoribosyl Pyrophosphate; Plasmids; Pyrimidine Nucleotides; Saccharomyces cerevisiae; Substrate Specificity; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

1997
Site-directed substitution of Ser1406 of hamster CAD with glutamic acid alters allosteric regulation of carbamyl phosphate synthetase II.
    Somatic cell and molecular genetics, 1997, Volume: 23, Issue:1

    Topics: Allosteric Regulation; Animals; Binding Sites; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cells, Cultured; Cricetinae; Genetic Complementation Test; Kinetics; Multienzyme Complexes; Phosphoribosyl Pyrophosphate; Phosphorylation; Point Mutation; Structure-Activity Relationship; Uridine Triphosphate

1997
Trapping an activated conformation of mammalian carbamyl-phosphate synthetase.
    The Journal of biological chemistry, 1997, Aug-08, Volume: 272, Issue:32

    Topics: Amino Acid Sequence; Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line; Cricetinae; Dihydroorotase; Escherichia coli; Kinetics; Mesocricetus; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Neoplasm Proteins; Phosphoribosyl Pyrophosphate; Protein Conformation; Recombinant Proteins; Uridine Triphosphate

1997
Regulation of carbamoyl phosphate synthetase by MAP kinase.
    Nature, 2000, Jan-20, Volume: 403, Issue:6767

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line; Cricetinae; Dihydroorotase; Enzyme Activation; Enzyme Inhibitors; Flavonoids; MAP Kinase Signaling System; Mesocricetus; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Phosphoribosyl Pyrophosphate; Phosphorylation; Pyrimidine Nucleotides; Rats; Uridine Triphosphate

2000
Growth-dependent regulation of mammalian pyrimidine biosynthesis by the protein kinase A and MAPK signaling cascades.
    The Journal of biological chemistry, 2002, May-03, Volume: 277, Issue:18

    Topics: Allosteric Regulation; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Cell Division; Cell Line; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Kidney; Kinetics; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Phosphoribosyl Pyrophosphate; Phosphorylation; Pyrimidines; Recombinant Proteins; Transfection; Uridine Triphosphate

2002
Substitutions in hamster CAD carbamoyl-phosphate synthetase alter allosteric response to 5-phosphoribosyl-alpha-pyrophosphate (PRPP) and UTP.
    The Biochemical journal, 2004, Mar-15, Volume: 378, Issue:Pt 3

    Topics: Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cricetinae; Dihydroorotase; Escherichia coli; Lysine; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Phosphoribosyl Pyrophosphate; Sequence Homology, Amino Acid; Serine; Tryptophan; Uridine Triphosphate

2004
Key role of uridine kinase and uridine phosphorylase in the homeostatic regulation of purine and pyrimidine salvage in brain.
    Neurochemistry international, 2007, Volume: 51, Issue:8

    Topics: Animals; Brain; Brain Chemistry; Cytidine Triphosphate; Homeostasis; Humans; Male; Nucleic Acids; Nucleosides; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Rats; Rats, Sprague-Dawley; Ribosemonophosphates; Subcellular Fractions; Tumor Cells, Cultured; Uridine Kinase; Uridine Phosphorylase; Uridine Triphosphate

2007