phosphoribosyl pyrophosphate has been researched along with thioguanine anhydrous in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seegmiller, JE; Skaper, SD; Spector, EB | 1 |
| Coffino, P; Friedrich, U | 1 |
| Becker, MA; Husain, K; Kim, M | 1 |
| Epstein, J; Harkrader, RJ; Jackson, RC; Ross, DA | 1 |
| Lee, SH; Sartorelli, AC | 1 |
| Phang, JM; Yeh, GC | 1 |
| Bhalla, K; Deitch, A; Grant, S; Nayak, R | 1 |
| Anderson, PJ; Chang, HC; Esty, AC; Friedmann, T; Jolly, DJ; Jones, OW; Miller, AD; Plent, MM; Seegmiller, JE; Willis, RC | 1 |
| Epstein, J; Preisler, HD | 1 |
| Elisseyeff, Y; Goker, E; Guarino, L; Kheradpour, A; Meyers, PA; Tan, CT; Tong, WP; Trippett, T; VanSyckle, KM; Wollner, N | 1 |
1 trial(s) available for phosphoribosyl pyrophosphate and thioguanine anhydrous
| Article | Year |
|---|---|
Pharmacologic-guided trial of sequential methotrexate and thioguanine in children with advanced malignancies.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Leukemia; Lymphoma; Male; Methotrexate; Neoplasms; Phosphoribosyl Pyrophosphate; Remission Induction; Thioguanine | 1994 |
9 other study(ies) available for phosphoribosyl pyrophosphate and thioguanine anhydrous
| Article | Year |
|---|---|
Reversion in expression of hypoxanthine-guanine phosphoribosyltransferase in 6-thioguanine resistant neuroblastoma: evidence for reduced enzyme levels associated with unaltered catalytic activity.
Topics: Adenine Phosphoribosyltransferase; Cell Line; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Immunoassay; Kinetics; Mutation; Neuroblastoma; Phosphoribosyl Pyrophosphate; Thioguanine | 1977 |
Hypoxanthine-guanine phosphoribosyl transferase with altered substrate affinity in mutant mouse lymphoma cells.
Topics: Aminopterin; Animals; Cells, Cultured; Drug Resistance; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lymphoma; Mice; Mutagens; Mutation; Pentosephosphates; Phosphoribosyl Pyrophosphate; Temperature; Thioguanine; Thymidine | 1977 |
PRPP and purine nucleotide metabolism in human lymphoblasts with both PRPP synthetase superactivity and HGPRT deficiency.
Topics: B-Lymphocytes; Cell Division; Cell Line; Humans; Hypoxanthine Phosphoribosyltransferase; Methylthioinosine; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Purine Nucleotides; Purines; Ribose-Phosphate Pyrophosphokinase; Thioguanine | 1989 |
Biochemical approaches to enhancement of antitumor drug selectivity: selective protection of cells from 6-thioguanine and 6-mercaptopurine by adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Count; Cell Line; Drug Interactions; Drug Resistance; Liver Neoplasms, Experimental; Mercaptopurine; Phosphoribosyl Pyrophosphate; Rats; Thioguanine; Uridine Diphosphate; Uridine Triphosphate | 1980 |
Biochemical mechanism of resistance of cultured sarcoma 180 cells to 6-thioguanine.
Topics: Alkaline Phosphatase; Animals; Cells, Cultured; Drug Resistance; Female; Hypoxanthine Phosphoribosyltransferase; Mice; Mice, Inbred Strains; Phosphoribosyl Pyrophosphate; Sarcoma 180; Thioguanine | 1981 |
Pyrroline-5-carboxylate stimulates the conversion of purine antimetabolites to their nucleotide forms by a redox-dependent mechanism.
Topics: Azathioprine; Erythrocytes; Humans; Inosine Monophosphate; Inosine Nucleotides; Mercaptopurine; Oxidation-Reduction; Phosphates; Phosphoribosyl Pyrophosphate; Pyrroles; Thioguanine; Thionucleotides | 1983 |
Synergistic interaction between acivicin (AT-125) and 6-thioguanine in the murine leukemia L1210. Biochemical and cytokinetic considerations.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Cycle; Cell Survival; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Guanine Nucleotides; Isoxazoles; Leukemia L1210; Mice; Oxazoles; Phosphoribosyl Pyrophosphate; RNA, Neoplasm; Thioguanine | 1984 |
Partial phenotypic correction of human Lesch-Nyhan (hypoxanthine-guanine phosphoribosyltransferase-deficient) lymphoblasts with a transmissible retroviral vector.
Topics: Animals; B-Lymphocytes; DNA; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Male; Mice; Phenotype; Phosphoribosyl Pyrophosphate; Purines; Repetitive Sequences, Nucleic Acid; Retroviridae; Thioguanine; Transcription, Genetic; Transfection | 1984 |
Protection of normal hematopoietic stem cells from the toxicity of purine base analogs: in vivo application.
Topics: Adenosine; Animals; Antimetabolites, Antineoplastic; Colony-Forming Units Assay; Hematopoietic Stem Cells; Mice; Phosphoribosyl Pyrophosphate; Purines; Thioguanine; Uridine | 1984 |