Page last updated: 2024-08-18

phosphoribosyl pyrophosphate and methylthioinosine

phosphoribosyl pyrophosphate has been researched along with methylthioinosine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Colofiore, JR; Koutcher, JA; Martin, DS; Nord, LD; Stolfi, RL1
Colofiore, J; Comis, RL; Hoffman, J; Hudes, GR; LaCreta, FP; Martin, DS; O'Dwyer, PJ; Ozols, RF; Walczak, J1
Becker, MA; Husain, K; Kim, M1
Kufe, DW; Peters, WP; Weiss, G1
Bökkerink, JP; De Abreu, RA; Lambooy, LH; Stet, EH; Trijbels, FJ; Vogt, MH1
Bonnac, LF; Cheeran, MC; Dreis, CD; Edwards, TC; Geraghty, RJ; Krishna, VD; Qiu, L; Soto-Acosta, R; Xie, J1

Trials

1 trial(s) available for phosphoribosyl pyrophosphate and methylthioinosine

ArticleYear
Phase I trial of fluorouracil modulation by N-phosphonacetyl-L-aspartate and 6-methylmercaptopurine riboside: optimization of 6-methylmercaptopurine riboside dose and schedule through biochemical analysis of sequential tumor biopsy specimens.
    Journal of the National Cancer Institute, 1991, Sep-04, Volume: 83, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Biopsy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Drug Interactions; Female; Fluorouracil; Humans; Male; Methylthioinosine; Middle Aged; Neoplasms; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate

1991

Other Studies

5 other study(ies) available for phosphoribosyl pyrophosphate and methylthioinosine

ArticleYear
Biochemical modulation of tumor cell energy: regression of advanced spontaneous murine breast tumors with a 5-fluorouracil-containing drug combination.
    Cancer research, 1992, Aug-01, Volume: 52, Issue:15

    Topics: 6-Aminonicotinamide; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methylthioinosine; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Orotic Acid; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate

1992
PRPP and purine nucleotide metabolism in human lymphoblasts with both PRPP synthetase superactivity and HGPRT deficiency.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: B-Lymphocytes; Cell Division; Cell Line; Humans; Hypoxanthine Phosphoribosyltransferase; Methylthioinosine; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Purine Nucleotides; Purines; Ribose-Phosphate Pyrophosphokinase; Thioguanine

1989
Phase-I trial of combination therapy with continuous-infusion MMPR and continuous-infusion 5-FU.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Fluorouracil; Humans; Inosine; Male; Methylthioinosine; Middle Aged; Neoplasms; Phosphoribosyl Pyrophosphate; RNA, Neoplasm

1984
The importance of methylthio-IMP for methylmercaptopurine ribonucleoside (Me-MPR) cytotoxicity in Molt F4 human malignant T-lymphoblasts.
    Biochimica et biophysica acta, 1993, Apr-30, Volume: 1181, Issue:2

    Topics: Cell Division; Cell Survival; Humans; Inosine Monophosphate; Mercaptopurine; Methylthioinosine; Phosphoribosyl Pyrophosphate; Purine Nucleotides; T-Lymphocytes; Thioinosine; Thionucleosides; Thionucleotides; Tumor Cells, Cultured

1993
Enhancing the Antiviral Potency of Nucleobases for Potential Broad-Spectrum Antiviral Therapies.
    Viruses, 2021, 12-14, Volume: 13, Issue:12

    Topics: Adenosine Triphosphate; Amides; Animals; Antimetabolites; Antiviral Agents; Cell Line; Drug Synergism; Guanosine Triphosphate; Humans; Methylthioinosine; Mutation; Phosphoribosyl Pyrophosphate; Pyrazines; RNA Viruses; RNA, Viral; Virus Replication

2021