phosphoribosyl pyrophosphate has been researched along with mercaptopurine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allison, AC; Hovi, T; Watts, RW; Webster, AD | 1 |
| Higuchi, T; Nakamura, T; Wakisaka, G | 1 |
| Higuchi, T; Nakamura, T; Uchino, H; Wakisaka, G | 1 |
| Higuchi, T | 1 |
| Liliemark, J; Peterson, C; Pettersson, B | 1 |
| Durkacz, BW; Harris, AL; Moses, K; Willmore, E | 1 |
| Chabner, BA; Johnson, GE; Poplack, DG; Zimm, S | 1 |
| Murphy, RF; Poplack, DG; Reaman, G; Zimm, S | 1 |
| Bakker, MA; Bökkerink, JP; de Abreu, RA; de Bruijn, CH; Hulscher, TW; Schretlen, ED; van Laarhoven, JP | 1 |
| Bakker, MA; Bökkerink, JP; De Abreu, RR; De Bruyn, CH; Hulscher, TW; Schretlen, ED; van Laarhoven, JP | 1 |
| Bakker, MA; Bökkerink, JP; De Abreu, RA; Hulscher, TW; Schretlen, ED | 1 |
| Epstein, J; Harkrader, RJ; Jackson, RC; Ross, DA | 1 |
| Phang, JM; Yeh, GC | 1 |
| Bakker, MA; Bökkerink, JP; Damen, FJ; De Abreu, RA; Hulscher, TW; Stet, EH; van Baal, JA | 1 |
| Bökkerink, JP; De Abreu, RA; Lambooy, LH; Stet, EH; Trijbels, FJ; Vogt, MH | 1 |
1 review(s) available for phosphoribosyl pyrophosphate and mercaptopurine
| Article | Year |
|---|---|
The role of de novo purine synthesis in lymphocyte transformation.
Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; Adolescent; Adult; Allopurinol; Azaserine; B-Lymphocytes; Child; Child, Preschool; Humans; Hypoxanthine Phosphoribosyltransferase; Immunoglobulins; Lectins; Lesch-Nyhan Syndrome; Lymphocyte Activation; Male; Mercaptopurine; Mitogens; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase; Purines; RNA; T-Lymphocytes; Thymidine; Uridine | 1977 |
14 other study(ies) available for phosphoribosyl pyrophosphate and mercaptopurine
| Article | Year |
|---|---|
Metabolism of 6-mercaptopurine in human leukemic cells.
Topics: Amidophosphoribosyltransferase; Animals; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Leukemia; Leukemia L1210; Leukemia, Myeloid, Acute; Leukocytes; Mercaptopurine; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase | 1976 |
Comparative study of 6-mercaptopurine metabolism in human leukemic leukocytes and L1210 cells.
Topics: Animals; Erythrocytes; Humans; In Vitro Techniques; Leukemia; Leukemia L1210; Leukocytes; Mercaptopurine; Mice; Phosphoribosyl Pyrophosphate; Thioinosine | 1977 |
Phosphorylation of 6-mercaptopurine in human leukemic cells and phosphoribosylpyrophosphate.
Topics: Acute Disease; Adult; Female; Humans; Leukemia; Leukocytes; Male; Mercaptopurine; Middle Aged; Pentosephosphates; Phosphoribosyl Pyrophosphate | 1975 |
On the biochemical modulation of 6-mercaptopurine by methotrexate in murine WEHI-3b leukemia cells in vitro.
Topics: Animals; Drug Interactions; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Kinetics; Leukemia, Experimental; Leukemia, Myelomonocytic, Acute; Mercaptopurine; Methotrexate; Mice; Phosphoribosyl Pyrophosphate; Purines; Thionucleotides; Tumor Cells, Cultured; Xanthines | 1992 |
Correlation of enhanced 6-mercaptopurine cytotoxicity with increased phosphoribosylpyrophosphate levels in Chinese hamster ovary cells treated with 3-aminobenzamide.
Topics: Animals; Azathioprine; Benzamides; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Drug Synergism; Flow Cytometry; In Vitro Techniques; Mercaptopurine; NAD; Pentosephosphates; Phosphoribosyl Pyrophosphate; Poly(ADP-ribose) Polymerase Inhibitors | 1990 |
Cellular pharmacokinetics of mercaptopurine in human neoplastic cells and cell lines.
Topics: Adenosine Triphosphate; Cell Line; Chromatography, High Pressure Liquid; Guanosine Triphosphate; Humans; Kinetics; Leukemia; Mercaptopurine; Neoplasms; Nucleotides; Phosphoribosyl Pyrophosphate | 1985 |
Biochemical parameters of mercaptopurine activity in patients with acute lymphoblastic leukemia.
Topics: Alkaline Phosphatase; Blood Cells; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Leukemia, Lymphoid; Male; Mercaptopurine; Pentosephosphates; Phosphoribosyl Pyrophosphate | 1986 |
Increased availability of phosphoribosyl pyrophosphate as the basis for enhanced 6-mercaptopurine incorporation by methotrexate, in cultured human lymphoblasts.
Topics: B-Lymphocytes; Cell Line; Humans; Mercaptopurine; Methotrexate; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purines; T-Lymphocytes | 1986 |
Sequence-, time- and dose-dependent synergism of methotrexate and 6-mercaptopurine in malignant human T-lymphoblasts.
Topics: Aminoimidazole Carboxamide; Cell Line; Drug Synergism; Glutamine; Glycine; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Phosphoribosyl Pyrophosphate; Purines; Ribonucleotides; T-Lymphocytes | 1986 |
Purine de novo synthesis as the basis of synergism of methotrexate and 6-mercaptopurine in human malignant lymphoblasts of different lineages.
Topics: Aminoimidazole Carboxamide; Drug Synergism; Glycine; Humans; Hypoxanthine; Hypoxanthines; Leukemia; Lymphocytes; Mercaptopurine; Methotrexate; Phosphoribosyl Pyrophosphate; Purines; Ribonucleotides; Tumor Cells, Cultured | 1988 |
Biochemical approaches to enhancement of antitumor drug selectivity: selective protection of cells from 6-thioguanine and 6-mercaptopurine by adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Count; Cell Line; Drug Interactions; Drug Resistance; Liver Neoplasms, Experimental; Mercaptopurine; Phosphoribosyl Pyrophosphate; Rats; Thioguanine; Uridine Diphosphate; Uridine Triphosphate | 1980 |
Pyrroline-5-carboxylate stimulates the conversion of purine antimetabolites to their nucleotide forms by a redox-dependent mechanism.
Topics: Azathioprine; Erythrocytes; Humans; Inosine Monophosphate; Inosine Nucleotides; Mercaptopurine; Oxidation-Reduction; Phosphates; Phosphoribosyl Pyrophosphate; Pyrroles; Thioguanine; Thionucleotides | 1983 |
6-Mercaptopurine: cytotoxicity and biochemical pharmacology in human malignant T-lymphoblasts.
Topics: Carbon Radioisotopes; Cell Cycle; DNA; Humans; Inosine Monophosphate; Leukemia, Lymphoid; Mercaptopurine; Phosphoribosyl Pyrophosphate; Phosphorus Radioisotopes; Ribonucleotides; RNA; Stem Cells; T-Lymphocytes; Thionucleotides | 1993 |
The importance of methylthio-IMP for methylmercaptopurine ribonucleoside (Me-MPR) cytotoxicity in Molt F4 human malignant T-lymphoblasts.
Topics: Cell Division; Cell Survival; Humans; Inosine Monophosphate; Mercaptopurine; Methylthioinosine; Phosphoribosyl Pyrophosphate; Purine Nucleotides; T-Lymphocytes; Thioinosine; Thionucleosides; Thionucleotides; Tumor Cells, Cultured | 1993 |