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phosphoribosyl pyrophosphate and inosinic acid

phosphoribosyl pyrophosphate has been researched along with inosinic acid in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199022 (68.75)18.7374
1990's7 (21.88)18.2507
2000's3 (9.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Henderson, JF1
Holmes, EW; Wyngaarden, JB1
Nyhan, WL1
Higuchi, T; Nakamura, T; Wakisaka, G1
Badenoch-Jones, P; Buttery, PJ1
Gutensohn, W1
Liliemark, J; Peterson, C; Pettersson, B1
Carlucci, F; Dispensa, E; Marinello, E; Molinelli, M; Pagani, R; Pizzichini, M; Tabucchi, A; Valerio, P1
Bowditch, J; Brown, AK; Dow, JW; Raeside, DL1
Gerber, G; Giacomello, A; Salerno, C1
Nuki, G; Rylance, HJ; Wallace, RC1
Tomoda, A; Yagawa, K; Yoneyama, Y1
Barankiewicz, J; Cohen, A1
Phang, JM; Yeh, GC2
Berman, PA; Black, DA; Harley, EH; Human, L1
Camici, M; Cellini, F; Del Corso, A; Ipata, PL; Mura, U; Turchi, G1
Ikegami, T; Natsumeda, Y; Olah, E; Weber, G1
Ikegami, T; Natsumeda, Y; Weber, G; Yamada, Y; Yamaji, Y1
Cartier, P; Hamet, M1
Barratt, E; Boorman, KN; Buttery, PJ1
Watts, RW1
Buttin, G; Colella, CM; Debatisse, M; Simili, M1
Harris, SC; Nagel, RL; Phang, JM; Rinaldi, A; Roth, EF; Yeh, GC1
Ahmed, N; Weidemann, MJ1
Bakker, MA; Bökkerink, JP; Damen, FJ; De Abreu, RA; Hulscher, TW; Stet, EH; van Baal, JA1
Bökkerink, JP; De Abreu, RA; Lambooy, LH; Stet, EH; Trijbels, FJ; Vogt, MH1
Eads, J; Grubmeyer, C; Sacchettini, JC; Xu, Y1
Furneaux, RH; Girvin, ME; Grubmeyer, C; Kicska, G; Li, CM; Schramm, VL; Tyler, PC; Xu, Y1
Craig, SP; Eakin, AE; Lee, CC; Medrano, FJ1
Chen, Q; Gu, X; Liang, Y; Luo, M; Su, X; Zheng, X1
Brereton, IM; de Jersey, J; Guddat, LW; Keough, DT1

Reviews

2 review(s) available for phosphoribosyl pyrophosphate and inosinic acid

ArticleYear
Molecular nature of enzyme regulation in purine biosynthesis.
    Ciba Foundation symposium, 1977, Issue:48

    Topics: Amidophosphoribosyltransferase; Animals; Female; Glucosephosphate Dehydrogenase Deficiency; Glutamine; Gout; Humans; Inosine Monophosphate; Kinetics; Liver; Molecular Weight; Nucleotidases; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Phosphotransferases; Placenta; Pregnancy; Purine Nucleotides; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates; Xanthine Oxidase

1977
Molecular variation in relation to purine metabolism.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1974, Volume: 8

    Topics: Amidophosphoribosyltransferase; Chemical Phenomena; Chemistry; Glucosephosphate Dehydrogenase Deficiency; Glutathione Reductase; Gout; Humans; Inosine Monophosphate; Lesch-Nyhan Syndrome; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid; Xanthine Oxidase; Xanthines; Xeroderma Pigmentosum

1974

Other Studies

30 other study(ies) available for phosphoribosyl pyrophosphate and inosinic acid

ArticleYear
Inosine triphosphate metabolism in human erythrocytes.
    Advances in experimental medicine and biology, 1977, Volume: 76A

    Topics: Erythrocytes; Humans; Hydrogen-Ion Concentration; Inosine Monophosphate; Inosine Nucleotides; Nucleotides; Oxygen; Phosphates; Phosphoribosyl Pyrophosphate; Pyrophosphatases; Pyruvates; Temperature

1977
Genetic heterogeneity at the locus for hypoxanthine-guanine phosphoribosyltransferase.
    Ciba Foundation symposium, 1977, Issue:48

    Topics: 5-Hydroxytryptophan; Erythrocytes; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Isoenzymes; Kinetics; Lesch-Nyhan Syndrome; Male; Phosphoribosyl Pyrophosphate

1977
Metabolism of 6-mercaptopurine in human leukemic cells.
    Cancer research, 1976, Volume: 36, Issue:10

    Topics: Amidophosphoribosyltransferase; Animals; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Leukemia; Leukemia L1210; Leukemia, Myeloid, Acute; Leukocytes; Mercaptopurine; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase

1976
The effects of added purines on urate and purine synthesis de novo by isolated chick liver, kidney and lymphoid cells.
    The Biochemical journal, 1976, Sep-15, Volume: 158, Issue:3

    Topics: Adenine; Adenosine Monophosphate; Animals; Chickens; Formates; Glycine; Guanine; Guanine Nucleotides; In Vitro Techniques; Inosine; Inosine Monophosphate; Kidney; Liver; Lymphoid Tissue; Phosphoribosyl Pyrophosphate; Purines; Stimulation, Chemical; Uric Acid

1976
Hypoxanthine phosphoribosyltransferase and hypoxanthine uptake in human erythrocytes.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1975, Volume: 356, Issue:7

    Topics: Cell Membrane; Cell Membrane Permeability; Erythrocytes; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Kinetics; Phosphates; Phosphoribosyl Pyrophosphate; Sodium Chloride

1975
On the biochemical modulation of 6-mercaptopurine by methotrexate in murine WEHI-3b leukemia cells in vitro.
    Leukemia research, 1992, Volume: 16, Issue:3

    Topics: Animals; Drug Interactions; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Kinetics; Leukemia, Experimental; Leukemia, Myelomonocytic, Acute; Mercaptopurine; Methotrexate; Mice; Phosphoribosyl Pyrophosphate; Purines; Thionucleotides; Tumor Cells, Cultured; Xanthines

1992
Purine de novo synthesis and enzymes at the inosinic branch point in human lymphocytes.
    Biochemical Society transactions, 1991, Volume: 19, Issue:3

    Topics: Adenylosuccinate Lyase; Adenylosuccinate Synthase; Carbon-Nitrogen Ligases; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Ligases; Lymphocytes; Phosphoribosyl Pyrophosphate; Purines

1991
Metabolism and salvage of adenine and hypoxanthine by myocytes isolated from mature rat heart.
    Biochimica et biophysica acta, 1985, Jun-30, Volume: 845, Issue:3

    Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Enzymes; Guanosine Monophosphate; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine Monophosphate; Myocardium; Phosphoribosyl Pyrophosphate; Rats; Ribose

1985
Regulatory aspects of hypoxanthine uptake by human erythrocytes.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Diphosphoglyceric Acids; Erythrocyte Membrane; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine Monophosphate; Oxygen; Pentosephosphates; Phosphates; Phosphoribosyl Pyrophosphate

1986
A method for the determination of 5-phosphoribosyl 1-pyrophosphate concentrations in erythrocytes using high-performance liquid chromatography.
    Analytical biochemistry, 1987, Feb-01, Volume: 160, Issue:2

    Topics: Chromatography, High Pressure Liquid; Erythrocytes; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Male; Pentosephosphates; Phosphoribosyl Pyrophosphate

1987
Accumulation of inosine 5'-monophosphate in human erythrocytes incubated with inosine.
    Biomedica biochimica acta, 1987, Volume: 46, Issue:2-3

    Topics: Adenine Nucleotides; Blood Glucose; Cytidine Monophosphate; Erythrocytes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine; Inosine Monophosphate; Inosine Nucleotides; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase

1987
Purine nucleotide metabolism in phytohemagglutinin-induced human T lymphocytes.
    Archives of biochemistry and biophysics, 1987, Volume: 258, Issue:1

    Topics: Adenine; Adenine Nucleotides; DNA; Guanine; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phytohemagglutinins; Purine Nucleotides; RNA; T-Lymphocytes

1987
Stimulation of phosphoribosyl pyrophosphate and purine nucleotide production by pyrroline 5-carboxylate in human erythrocytes.
    The Journal of biological chemistry, 1988, Sep-15, Volume: 263, Issue:26

    Topics: Adenine Nucleotides; Adult; Blood Glucose; Erythrocytes; Humans; Inosine Monophosphate; Oxidation-Reduction; Pentose Phosphate Pathway; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrroles; Ribonucleotides

1988
Oxypurine cycle in human erythrocytes regulated by pH, inorganic phosphate, and oxygen.
    The Journal of clinical investigation, 1988, Volume: 82, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Erythrocytes; Humans; Hydrogen-Ion Concentration; Hypoxanthines; Inosine Monophosphate; Oxygen; Partial Pressure; Phosphates; Phosphoribosyl Pyrophosphate

1988
Alpha-5-phosphoribosyl-1-pyrophosphate-independent salvage of purines in cultured Chinese hamster lung fibroblasts.
    Archives of biochemistry and biophysics, 1988, Volume: 265, Issue:2

    Topics: Animals; Azaguanine; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Lung; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Purine-Nucleoside Phosphorylase; Ribosemonophosphates

1988
Significance of purine salvage in circumventing the action of antimetabolites in rat hepatoma cells.
    Cancer research, 1989, Jan-01, Volume: 49, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Isoxazoles; Kinetics; Liver Neoplasms, Experimental; Phosphoribosyl Pyrophosphate; Purines; Rats

1989
Channeling of IMP into guanylate synthesis in the growth program of hepatoma 3924A cells.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenine Nucleotides; Amidophosphoribosyltransferase; Animals; Cell Cycle; Guanine Nucleotides; Inosine Monophosphate; Inosine Nucleotides; Liver Neoplasms, Experimental; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Tumor Cells, Cultured

1989
The normal metabolism of uric acid.
    Advances in nephrology from the Necker Hospital, 1974, Volume: 3

    Topics: Adenosine Monophosphate; Glutamine; Guanosine Monophosphate; Humans; Inosine Monophosphate; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Uric Acid

1974
Urate synthesis in the perfused chick liver.
    The Biochemical journal, 1974, Volume: 144, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ammonium Chloride; Animals; Aspartic Acid; Carbon Radioisotopes; Chickens; Glutamine; Glycine; Inosine; Inosine Monophosphate; Insulin; Liver; Oxygen Consumption; Perfusion; Phosphoribosyl Pyrophosphate; Ribonucleosides; Tritium; Uric Acid; Xanthines

1974
Increased inhibition of HGPRT by IMP and GMP and higher levels of PRPP in an 8-azaguanine - hat resistant mutant of Chinese hamster cells.
    Cell biology international reports, 1983, Volume: 7, Issue:2

    Topics: Animals; Azaguanine; Cell Line; Cricetinae; Culture Media; Guanine Nucleotides; Guanosine Monophosphate; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Inosine Nucleotides; Kinetics; Mutation; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase

1983
Pyrroline-5-carboxylate stimulates the conversion of purine antimetabolites to their nucleotide forms by a redox-dependent mechanism.
    The Journal of biological chemistry, 1983, Aug-25, Volume: 258, Issue:16

    Topics: Azathioprine; Erythrocytes; Humans; Inosine Monophosphate; Inosine Nucleotides; Mercaptopurine; Oxidation-Reduction; Phosphates; Phosphoribosyl Pyrophosphate; Pyrroles; Thioguanine; Thionucleotides

1983
The effect of pyrroline-5-carboxylic acid on nucleotide metabolism in erythrocytes from normal and glucose-6-phosphate dehydrogenase-deficient subjects.
    The Journal of biological chemistry, 1984, May-10, Volume: 259, Issue:9

    Topics: Erythrocytes; Glucosephosphate Dehydrogenase Deficiency; Humans; Inosine Monophosphate; Kinetics; NADP; Oxidation-Reduction; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Reference Values

1984
Biochemical effect of three different inhibitors of purine/pyrimidine metabolism on differentiation in HL60 cells.
    Leukemia research, 1995, Volume: 19, Issue:4

    Topics: Alanine; Cell Differentiation; Cell Division; Formates; Hematopoiesis; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine Monophosphate; Isoxazoles; Leukemia, Myeloid; Mycophenolic Acid; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Reactive Oxygen Species; Tumor Cells, Cultured

1995
6-Mercaptopurine: cytotoxicity and biochemical pharmacology in human malignant T-lymphoblasts.
    Biochemical pharmacology, 1993, Apr-06, Volume: 45, Issue:7

    Topics: Carbon Radioisotopes; Cell Cycle; DNA; Humans; Inosine Monophosphate; Leukemia, Lymphoid; Mercaptopurine; Phosphoribosyl Pyrophosphate; Phosphorus Radioisotopes; Ribonucleotides; RNA; Stem Cells; T-Lymphocytes; Thionucleotides

1993
The importance of methylthio-IMP for methylmercaptopurine ribonucleoside (Me-MPR) cytotoxicity in Molt F4 human malignant T-lymphoblasts.
    Biochimica et biophysica acta, 1993, Apr-30, Volume: 1181, Issue:2

    Topics: Cell Division; Cell Survival; Humans; Inosine Monophosphate; Mercaptopurine; Methylthioinosine; Phosphoribosyl Pyrophosphate; Purine Nucleotides; T-Lymphocytes; Thioinosine; Thionucleosides; Thionucleotides; Tumor Cells, Cultured

1993
Kinetic mechanism of human hypoxanthine-guanine phosphoribosyltransferase: rapid phosphoribosyl transfer chemistry.
    Biochemistry, 1997, Mar-25, Volume: 36, Issue:12

    Topics: Guanine; Guanosine Monophosphate; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Kinetics; Models, Chemical; Models, Molecular; Phosphoribosyl Pyrophosphate; Protein Conformation; Recombinant Proteins

1997
Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases.
    Nature structural biology, 1999, Volume: 6, Issue:6

    Topics: Animals; Binding Sites; Catalysis; Diphosphates; Drug Design; Enzyme Inhibitors; Guanosine Monophosphate; Humans; Hydrogen Bonding; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Kinetics; Magnesium Compounds; Nuclear Magnetic Resonance, Biomolecular; Phosphoribosyl Pyrophosphate; Phosphorylation; Plasmodium falciparum; Protein Binding; Protons; Purine Nucleosides; Pyrimidinones; Pyrroles

1999
Investigation of the functional role of active site loop II in a hypoxanthine phosphoribosyltransferase.
    Biochimica et biophysica acta, 2001, Jul-27, Volume: 1537, Issue:1

    Topics: Animals; Binding Sites; Catalysis; Diphosphates; Gene Deletion; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Kinetics; Models, Molecular; Mutation; Phosphoribosyl Pyrophosphate; Trypanosoma cruzi

2001
Alternative IMP binding in feedback inhibition of hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis.
    Journal of molecular biology, 2005, May-20, Volume: 348, Issue:5

    Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Feedback, Physiological; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Molecular Sequence Data; Molecular Structure; Phosphoribosyl Pyrophosphate; Protein Conformation; Thermoanaerobacter

2005
The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle.
    Journal of molecular biology, 2005, Aug-05, Volume: 351, Issue:1

    Topics: Binding Sites; Catalysis; Crystallography, X-Ray; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Phosphoribosyl Pyrophosphate; Protein Binding; Protein Conformation; Pyrazoles; Pyrimidines

2005