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phosphoribosyl pyrophosphate and inosine

phosphoribosyl pyrophosphate has been researched along with inosine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199022 (73.33)18.7374
1990's6 (20.00)18.2507
2000's1 (3.33)29.6817
2010's1 (3.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hershfield, MS; Seegmiller, JE; Spector, EB1
Reem, GH1
Schreier, MH; Seegmiller, JE; Watanabe, T1
Akkerman, JW; De Bree, PK; De Bruyn, CH; Siegenbeek Van Heukelom, LH; Staal, GE; Stoop, JW; Wadman, SK; Zegers, BJ1
Molnár, J1
Higuchi, T; Nakamura, T; Wakisaka, G1
Naguib, FN; Nash, D1
Ammann, AJ; Cohen, A; Doyle, D; Martin, DW1
Becker, MA2
Badenoch-Jones, P; Buttery, PJ1
Petersen, A; Quistorff, B2
Jezewska, MM; Trembacz, H1
Ropp, PA; Traut, TW1
Barankiewicz, J; Cohen, A1
Tomoda, A; Yagawa, K; Yoneyama, Y1
Ishijima, S; Kita, K; Tatibana, M1
Ishijima, S; Ishizuka, T; Kita, K; Suzuki, N; Tatibana, M1
Barratt, E; Boorman, KN; Buttery, PJ1
Lafleur, F; Lalanne, M1
Lankelma, J; Leyva, A; Nederbragt, H; Pinedo, HM1
Achterberg, PW; de Jong, JW; de Tombe, PP; Harmsen, E1
Micheli, V; Ricci, C1
Buttin, G; Debatisse, M; Fernandez-Mejia, C1
Kufe, DW; Peters, WP; Weiss, G1
Kuchel, PW; Lundberg, P; Roy, S1
Zimmer, HG1
Barsotti, C; Felice, F; Ipata, PL; Pesi, R1
Kivero, AD; Livshits, VA; Novikova, AE; Romanenkov, DV; Skripnikova, VS; Vitushkina, MV; Zakataeva, NP1

Reviews

3 review(s) available for phosphoribosyl pyrophosphate and inosine

ArticleYear
Purine biosynthesis in mutant mammalian cells.
    Ciba Foundation symposium, 1977, Issue:48

    Topics: Adenosine; Amidophosphoribosyltransferase; Amino Sugars; Animals; Cells, Cultured; Cricetinae; Dimethyl Sulfoxide; Fibroblasts; Formates; Glutamine; Glycine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Leukemia, Erythroblastic, Acute; Lung; Lymphocytes; Mutation; Phosphoribosyl Pyrophosphate; Purines; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates

1977
The effect of adenosine on lymphoid cell proliferation and antibody formation.
    Ciba Foundation symposium, 1977, Issue:48

    Topics: Adenosine; Adenosine Deaminase; Antibody Formation; Azepines; Cell Division; Cyclic AMP; Hemolytic Plaque Technique; Humans; Inosine; Lectins; Liver; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Phosphoribosyl Pyrophosphate; Ribonucleosides; Ribose-Phosphate Pyrophosphokinase; Spleen; Uridine

1977
Significance of the 5-phosphoribosyl-1-pyrophosphate pool for cardiac purine and pyrimidine nucleotide synthesis: studies with ribose, adenine, inosine, and orotic acid in rats.
    Cardiovascular drugs and therapy, 1998, Volume: 12 Suppl 2

    Topics: Adenine; Animals; Inosine; Myocardium; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Ribose

1998

Other Studies

27 other study(ies) available for phosphoribosyl pyrophosphate and inosine

ArticleYear
Purine synthesis and excretion in mutants of the WI-L2 human lymphoblastoid line deficient in adenosine kinase (AK) and adenine phosphoribosyltransferase (APRT).
    Advances in experimental medicine and biology, 1977, Volume: 76A

    Topics: Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Cell Line; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Inosine Nucleotides; Lymphocytes; Models, Biological; Mutation; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Phosphotransferases; Purines

1977
A patient with purine nucleoside phosphorylase deficiency: enzymological and metabolic aspects.
    Clinica chimica acta; international journal of clinical chemistry, 1977, Feb-01, Volume: 74, Issue:3

    Topics: Adenine; Adenosine; Child; Erythrocytes; Female; Humans; Hypoxanthines; Inosine; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase; Purines; Time Factors

1977
Adenine nucleotide synthesis and growth rate of the adenyl succinate lyase mutant of Bacillus anthracis.
    Acta microbiologica Academiae Scientiarum Hungaricae, 1975, Volume: 22, Issue:3

    Topics: Adenine; Adenine Nucleotides; Adenosine Monophosphate; Bacillus anthracis; Carbon Radioisotopes; Cell-Free System; Chromatography, Thin Layer; Hypoxanthines; Inosine; Ligases; Lyases; Mutation; Phosphoribosyl Pyrophosphate; Sonication; Succinates

1975
Metabolism of 6-mercaptopurine in human leukemic cells.
    Cancer research, 1976, Volume: 36, Issue:10

    Topics: Amidophosphoribosyltransferase; Animals; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Leukemia; Leukemia L1210; Leukemia, Myeloid, Acute; Leukocytes; Mercaptopurine; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase

1976
Nucleoside auxotrophy in Drosophila: an autosomal locus yielding mutants supplementable by purine and pyrimidine ribonucleosides.
    Molecular & general genetics : MGG, 1976, Aug-10, Volume: 147, Issue:1

    Topics: Adenosine; Alleles; Animals; Crosses, Genetic; Cytidine; Drosophila melanogaster; Female; Guanosine; Inosine; Male; Mutation; Phenotype; Phosphoribosyl Pyrophosphate; Ribonucleosides; RNA; Uridine

1976
Abnormal purine metabolism and purine overproduction in a patient deficient in purine nucleoside phosphorylase.
    The New England journal of medicine, 1976, Dec-23, Volume: 295, Issue:26

    Topics: Child; Erythrocytes; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Immunologic Deficiency Syndromes; Inosine; Lesch-Nyhan Syndrome; Male; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Purine Nucleosides; Purine Nucleotides; Purine-Nucleoside Phosphorylase; Purines; Uric Acid

1976
Effects of inosine on purine synthesis in normal and HGPRT-deficient human fibroblasts.
    Advances in experimental medicine and biology, 1977, Volume: 76A

    Topics: Cells, Cultured; Fibroblasts; Humans; Hypoxanthine Phosphoribosyltransferase; Inosine; Lesch-Nyhan Syndrome; Methylene Blue; Mutation; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines; Ribosemonophosphates

1977
Regulation of purine nucleotide synthesis. Effects of inosine on normal and hypoxantine-guanine phosphoribosyltransferase-deficient fibroblasts.
    Biochimica et biophysica acta, 1976, Jun-18, Volume: 435, Issue:2

    Topics: Adult; Child; Fibroblasts; Glucose; Humans; Hypoxanthine Phosphoribosyltransferase; Inosine; Kinetics; Lesch-Nyhan Syndrome; Methylene Blue; Phosphoribosyl Pyrophosphate; Skin

1976
The effects of added purines on urate and purine synthesis de novo by isolated chick liver, kidney and lymphoid cells.
    The Biochemical journal, 1976, Sep-15, Volume: 158, Issue:3

    Topics: Adenine; Adenosine Monophosphate; Animals; Chickens; Formates; Glycine; Guanine; Guanine Nucleotides; In Vitro Techniques; Inosine; Inosine Monophosphate; Kidney; Liver; Lymphoid Tissue; Phosphoribosyl Pyrophosphate; Purines; Stimulation, Chemical; Uric Acid

1976
Inosine/pyruvate/phosphate medium but not adenosine/pyruvate/phosphate medium introduces millimolar amounts of 5-phosphoribosyl 1-pyrophosphate in human erythrocytes. A 31P-n.m.r. study.
    The Biochemical journal, 1990, Mar-01, Volume: 266, Issue:2

    Topics: Adenosine; Culture Media; Erythrocytes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine; Magnetic Resonance Spectroscopy; Nucleotides; Pentosephosphates; Phosphoribosyl Pyrophosphate

1990
Induction of millimolar amounts of 5-phosphoribosyl-1-pyrophosphate in human erythrocytes by incubation in inosine-pyruvate-phosphate medium. A 31P-NMR study.
    Biomedica biochimica acta, 1990, Volume: 49, Issue:2-3

    Topics: Erythrocytes; Humans; Inosine; Magnetic Resonance Spectroscopy; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphorus Isotopes; Pyruvates

1990
The route of non-enzymic and enzymic breakdown of 5-phosphoribosyl 1-pyrophosphate to ribose 1-phosphate.
    The Biochemical journal, 1990, Nov-01, Volume: 271, Issue:3

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Aspergillus niger; Cattle; Hydrogen-Ion Concentration; Hydrolysis; Hypoxanthine Phosphoribosyltransferase; Inosine; Intestines; Phosphoribosyl Pyrophosphate; Phosphoric Monoester Hydrolases; Ribosemonophosphates; Solanum tuberosum

1990
Allosteric regulation of purine nucleoside phosphorylase.
    Archives of biochemistry and biophysics, 1991, Aug-01, Volume: 288, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Animals; Cattle; Inosine; Kinetics; Mathematics; Models, Theoretical; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase; Spleen; Uridine Triphosphate

1991
Purine nucleotide metabolism in resident and activated rat macrophages in vitro.
    European journal of immunology, 1985, Volume: 15, Issue:6

    Topics: Adenine; Adenosine; Animals; Cells, Cultured; Guanine; Guanosine; Hypoxanthine; Hypoxanthines; Inosine; Macrophage Activation; Macrophages; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Rats; Thioglycolates

1985
Accumulation of inosine 5'-monophosphate in human erythrocytes incubated with inosine.
    Biomedica biochimica acta, 1987, Volume: 46, Issue:2-3

    Topics: Adenine Nucleotides; Blood Glucose; Cytidine Monophosphate; Erythrocytes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine; Inosine Monophosphate; Inosine Nucleotides; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase

1987
External Mg2+-dependent early stimulation of nucleotide synthesis in Swiss 3T3 cells.
    The American journal of physiology, 1989, Volume: 257, Issue:6 Pt 1

    Topics: Amiloride; Animals; Bumetanide; Calcimycin; Carbon Radioisotopes; Cell Division; Cells, Cultured; Egtazic Acid; Epidermal Growth Factor; Furosemide; Inosine; Insulin; Kinetics; Magnesium; Mice; Phosphoribosyl Pyrophosphate; Radioisotope Dilution Technique; Ribonucleotides

1989
Early mitogenic stimulation of metabolic flux through phosphoribosyl pyrophosphate into nucleotides in Swiss 3T3 cells and requirement of external magnesium for the response.
    Advances in enzyme regulation, 1989, Volume: 28

    Topics: Animals; Bombesin; Calcimycin; Carbon Radioisotopes; Cell Division; Cells, Cultured; Egtazic Acid; Epidermal Growth Factor; Furosemide; Humans; Inosine; Insulin; Kinetics; Melitten; Mice; Pentosephosphates; Phosphoribosyl Pyrophosphate; Radioisotope Dilution Technique; Ribonucleotides

1989
Urate synthesis in the perfused chick liver.
    The Biochemical journal, 1974, Volume: 144, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ammonium Chloride; Animals; Aspartic Acid; Carbon Radioisotopes; Chickens; Glutamine; Glycine; Inosine; Inosine Monophosphate; Insulin; Liver; Oxygen Consumption; Perfusion; Phosphoribosyl Pyrophosphate; Ribonucleosides; Tritium; Uric Acid; Xanthines

1974
Inosine synthesis and phosphoribosylpyrophosphate availability in rat liver cells in the presence of allopurinol.
    Canadian journal of biochemistry, 1980, Volume: 58, Issue:8

    Topics: Adenine; Allopurinol; Animals; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Liver; Male; Pentosephosphates; Phosphates; Phosphoribosyl Pyrophosphate; Rats

1980
Methotrexate cytotoxicity: studies on its reversal by folates and nucleosides.
    Cancer treatment reports, 1981, Volume: 65 Suppl 1

    Topics: Animals; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Head and Neck Neoplasms; Humans; Hypoxanthines; Inosine; Leukemia L1210; Methotrexate; Mice; Nucleosides; Phosphoribosyl Pyrophosphate; Thymidine

1981
Enhanced ATP and GTP synthesis from hypoxanthine or inosine after myocardial ischemia.
    The American journal of physiology, 1984, Volume: 246, Issue:1 Pt 2

    Topics: Adenosine Triphosphate; Animals; Coronary Disease; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Inosine; Male; Phosphoribosyl Pyrophosphate; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines

1984
[Purine metabolism of the human erythrocyte].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1983, Volume: 19, Issue:1

    Topics: Adenosine; Erythrocyte Membrane; Erythrocytes; Humans; Inosine; Kinetics; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Phosphorylation; Phosphotransferases; Purine Nucleosides; Purine Nucleotides; Purines; Ribose-Phosphate Pyrophosphokinase

1983
Adenosine-resistant Chinese hamster fibroblast variants with hyperactive adenosine-deaminase: an analysis of the protection against exogenous adenosine afforded by increased activity of the deamination pathway.
    Journal of cellular physiology, 1984, Volume: 120, Issue:3

    Topics: Adenosine; Adenosine Deaminase; Animals; Cell Line; Coformycin; Cricetinae; Cricetulus; Drug Resistance; Fibroblasts; Hypoxanthine; Hypoxanthines; Inosine; Models, Chemical; Nucleoside Deaminases; Phosphoribosyl Pyrophosphate; Purines

1984
Phase-I trial of combination therapy with continuous-infusion MMPR and continuous-infusion 5-FU.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Fluorouracil; Humans; Inosine; Male; Methylthioinosine; Middle Aged; Neoplasms; Phosphoribosyl Pyrophosphate; RNA, Neoplasm

1984
Fructose 3-phosphate and 5-phosphoribosyl-1-pyrophosphate formation in perfused human erythrocytes: 31P NMR studies.
    Magnetic resonance in medicine, 1994, Volume: 31, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Alginates; Diphosphoglyceric Acids; Erythrocytes; Fructose; Fructosephosphates; Glucose; Humans; Inosine; Magnesium; Magnetic Resonance Spectroscopy; Perfusion; Phosphoenolpyruvate; Phosphoribosyl Pyrophosphate; Phosphorus; Pyruvates; Sepharose

1994
The purine nucleoside cycle in cell-free extracts of rat brain: evidence for the occurrence of an inosine and a guanosine cycle with distinct metabolic roles.
    Cellular and molecular life sciences : CMLS, 2003, Volume: 60, Issue:4

    Topics: Animals; Brain; Fluorouracil; Guanosine; Inosine; Male; Phosphoribosyl Pyrophosphate; Purine Nucleosides; Pyrimidines; Rats; Rats, Sprague-Dawley; Ribosemonophosphates

2003
Wild-type and feedback-resistant phosphoribosyl pyrophosphate synthetases from Bacillus amyloliquefaciens: purification, characterization, and application to increase purine nucleoside production.
    Applied microbiology and biotechnology, 2012, Volume: 93, Issue:5

    Topics: Adenosine Diphosphate; Amino Acid Substitution; Bacillus; Cloning, Molecular; Enzyme Inhibitors; Escherichia coli; Gene Expression; Guanosine; Guanosine Diphosphate; Inosine; Molecular Sequence Data; Mutant Proteins; Mutation, Missense; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Sequence Analysis, DNA

2012