phosphoribosyl pyrophosphate and fluorouracil

phosphoribosyl pyrophosphate has been researched along with fluorouracil in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (50.00)	18.7374
1990's	13 (34.21)	18.2507
2000's	4 (10.53)	29.6817
2010's	2 (5.26)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cadman, E; Davis, L; Heimer, R	1
Guganig, ME; Reyes, P	1
Bertino, JR; Colofiore, JR; Li, WW; Romanini, A	1
Colofiore, JR; Koutcher, JA; Martin, DS; Nord, LD; Stolfi, RL	1
Chen, TL; Erlichman, C	1
Coit, D; Colofiore, J; Kelsen, D; Martin, DS; Sawyer, R	1
Colofiore, J; Comis, RL; Hoffman, J; Hudes, GR; LaCreta, FP; Martin, DS; O'Dwyer, PJ; Ozols, RF; Walczak, J	1
Laurensse, EJ; Peters, GJ; Pinedo, HM; van Groeningen, CJ	1
Ardalan, B; Chandrasekaran, B; Hrishikeshavan, HJ	1
Klubes, P; Parker, WB	1
Ishioka, C; Kakuta, H; Kanamaru, R; Sato, T; Wakui, A	1
Kane, MA; Raptis, G; Roth, E; Schreiber, C; Waxman, S	1
Martin, DS; Sawyer, RC; Stolfi, RL	1
Colofiore, J; Derby, S; Kemeny, N; Martin, DS; Salvia, B; Sawyer, RC; Schneider, A	1
Dykes, DJ; Elliott, WL; Howard, CT; Leopold, WR	1
Laurensse, E; Leyva, A; Peters, GJ; Pinedo, HM	1
Benz, C; Cadman, E; Heimer, R	1
Benz, C; Cadman, E; Tattelman, E; Tillis, T	1
Fujii, S; Maehara, Y; Nagayama, S; Nakamura, H; Okazaki, H; Shirasaka, T	1
Ardalan, B; Corbett, T; Heck, D; Villacorte, D	1
Houghton, JA; Houghton, PJ	1
Browman, GP	1
Ahmed, T; Harper, HD; Kemeny, NE; Michaelson, RA; Yip, LC	1
Kufe, DW; Peters, WP; Weiss, G	1
Hoshi, A; Yoshida, M	1
André, M; Bertino, JR; Conti, JA; Goker, E; Kemeny, N; Ragusa, K; Seiter, K; Tong, W	1
Davis, SJ; Hartigan, DJ; Pizzorno, G; Russello, O	1
Daimon, A; Fukushima, M; Inaba, M; Koizumi, K; Miike, N; Mitsuhashi, J; Naoe, Y; Sawada, H; Tsujimoto, H	1
Chisena, CA; Cysyk, RL; Hyman, R; Monks, A	1
Bertino, JR; Chang, YM; Chou, TC; Gorlick, R; Izzo, J; Longo, GS; Tong, WP; Zielinski, Z	1
Inaba, M; Mitsuhashi, J; Naoe, Y	1
Hamada, H; Inaba, M; Sadata, A; Sawada, H	1
Bemi, V; Ipata, PL; Mascia, L; Turchi, G	1
Ipata, PL; Mascia, L	1
Barsotti, C; Ipata, PL	1
Barsotti, C; Felice, F; Ipata, PL; Pesi, R	1
Elferich, J; Forquer, I; Riscoe, MK; Shinde, U; Soysa, R; Ullman, B; Wilson, ZN; Yates, PA	1
Chen, Y; Du, L; Fang, H; Li, H; Li, Y; Wang, D; Xu, Y; Yang, F; Zheng, L; Zhou, BS	1

Trials

5 trial(s) available for phosphoribosyl pyrophosphate and fluorouracil

Article	Year
A phase II trial of biochemical modulation using N-phosphonacetyl-L-aspartate, high-dose methotrexate, high-dose 5-fluorouracil, and leucovorin in patients with adenocarcinoma of unknown primary site. Cancer, 1992, Oct-01, Volume: 70, Issue:7 Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Drug Evaluation; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasms, Unknown Primary; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate; Uridine Triphosphate	1992
Phase I trial of fluorouracil modulation by N-phosphonacetyl-L-aspartate and 6-methylmercaptopurine riboside: optimization of 6-methylmercaptopurine riboside dose and schedule through biochemical analysis of sequential tumor biopsy specimens. Journal of the National Cancer Institute, 1991, Sep-04, Volume: 83, Issue:17 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Biopsy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Drug Interactions; Female; Fluorouracil; Humans; Male; Methylthioinosine; Middle Aged; Neoplasms; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate	1991
Clinical application of the concept of methotrexate plus 5-FU sequence-dependent "synergy": how good is the evidence? Cancer treatment reports, 1984, Volume: 68, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; DNA; Drug Synergism; Fluorouracil; Humans; Immunosuppression Therapy; Mammary Neoplasms, Experimental; Methotrexate; Mice; Neoplasms; Phosphoribosyl Pyrophosphate; Rats; RNA; Sarcoma 180; Thymidylate Synthase	1984
Activity of sequential low-dose methotrexate and fluorouracil in advanced colorectal carcinoma: attempt at correlation with tissue and blood levels of phosphoribosylpyrophosphate. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Leukopenia; Lymphocytes; Male; Methotrexate; Middle Aged; Mucous Membrane; Nausea; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Prospective Studies; Rectal Neoplasms; Ribose-Phosphate Pyrophosphokinase; Thrombocytopenia; Vomiting	1984
Trial of sequential trimetrexate, fluorouracil, and high-dose leucovorin in previously treated patients with gastrointestinal carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Digestive System Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Phosphoribosyl Pyrophosphate; Survival Analysis; Treatment Outcome; Trimetrexate	1994

Other Studies

33 other study(ies) available for phosphoribosyl pyrophosphate and fluorouracil

Article	Year
Enhanced 5-fluorouracil nucleotide formation after methotrexate administration: explanation for drug synergism. Science (New York, N.Y.), 1979, Sep-14, Volume: 205, Issue:4411 Topics: Animals; Cells, Cultured; Drug Administration Schedule; Drug Synergism; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Phosphoribosyl Pyrophosphate; Ribonucleotides; RNA, Neoplasm; Thymidylate Synthase	1979
Studies on a pyrimidine phosphoribosyltransferase from murine leukemia P1534J. Partial purification, substrate specificity, and evidence for its existence as a bifunctional complex with orotidine 5-phosphate decarboxylase. The Journal of biological chemistry, 1975, Jul-10, Volume: 250, Issue:13 Topics: Animals; Carbon Radioisotopes; Carboxy-Lyases; Carboxylic Acids; Cells, Cultured; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Hot Temperature; Kinetics; Leukemia, Experimental; Mice; Orotic Acid; Pentosyltransferases; Peptide Hydrolases; Phosphoribosyl Pyrophosphate; Pyrimidines; Uracil; Uracil Nucleotides; Uridine Phosphorylase	1975
Leucovorin enhances cytotoxicity of trimetrexate/fluorouracil, but not methotrexate/fluorouracil, in CCRF-CEM cells. Journal of the National Cancer Institute, 1992, Jul-01, Volume: 84, Issue:13 Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; Humans; Leucovorin; Leukemia, Lymphoid; Methotrexate; Phosphoribosyl Pyrophosphate; Trimetrexate; Tumor Cells, Cultured	1992
Biochemical modulation of tumor cell energy: regression of advanced spontaneous murine breast tumors with a 5-fluorouracil-containing drug combination. Cancer research, 1992, Aug-01, Volume: 52, Issue:15 Topics: 6-Aminonicotinamide; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methylthioinosine; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Orotic Acid; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate	1992
Biochemical modulation of 5-fluorouracil with or without leucovorin by a low dose of brequinar in MGH-U1 cells. Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Cell Survival; Cytidine Triphosphate; Deoxyuracil Nucleotides; Dose-Response Relationship, Drug; Drug Interactions; Fluorodeoxyuridylate; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Leucovorin; Phosphoribosyl Pyrophosphate; Thymidylate Synthase; Tumor Cells, Cultured; Uridine Triphosphate	1992
A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa. Cancer, 1991, Nov-01, Volume: 68, Issue:9 Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Colon; Colonic Neoplasms; Fluorodeoxyuridylate; Fluorouracil; Humans; Intestinal Mucosa; Middle Aged; Orotate Phosphoribosyltransferase; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Pyrimidine Phosphorylases; Rectal Neoplasms; Ribosemonophosphates; Uracil Nucleotides; Uridine Triphosphate	1991
Biochemical mechanisms for the scheduled synergism of (alpha S, 5S)-2 amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid and 5-fluorouracil in P388 leukemia. Cancer chemotherapy and pharmacology, 1985, Volume: 15, Issue:1 Topics: Animals; Antibiotics, Antineoplastic; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Isoxazoles; Leukemia P388; Leukemia, Experimental; Mice; Oxazoles; Phosphoribosyl Pyrophosphate; Phosphotransferases	1985
Enhancement by uridine of the anabolism of 5-fluorouracil in mouse T-lymphoma (S-49) cells. Cancer research, 1985, Volume: 45, Issue:9 Topics: Animals; Cell Survival; Cells, Cultured; DNA; Fluorouracil; Lymphoma; Mice; Phosphoribosyl Pyrophosphate; Protein Biosynthesis; Pyrimidines; RNA; T-Lymphocytes; Tritium; Uridine; Uridine Triphosphate	1985
The efficacy of combined therapy with methotrexate and 5-fluorouracil from the view point of cellular PRPP level of L1210 cells and HeLa S3 cells. The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku, 1985, Volume: 32, Issue:1-4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; HeLa Cells; Humans; Leukemia L1210; Methotrexate; Mice; Pentosephosphates; Phosphoribosyl Pyrophosphate	1985
Effect of intracellular folate concentration on the modulation of 5-fluorouracil cytotoxicity by the elevation of phosphoribosylpyrophosphate in cultured human KB cells. Cancer research, 1987, Dec-15, Volume: 47, Issue:24 Pt 1 Topics: Adenosine; Carcinoma, Squamous Cell; Cell Survival; Fluorouracil; Folic Acid; Glucose; Humans; KB Cells; Leucovorin; Leukemia, Myeloid, Acute; Methotrexate; Nasopharyngeal Neoplasms; Pentosephosphates; Phosphoribosyl Pyrophosphate; Thymidine	1987
Effect of L-histidinol on the metabolism of 5-fluorouracil in the BALB/c x DBA/8 F1 murine tumor system. Cancer research, 1988, Dec-01, Volume: 48, Issue:23 Topics: Animals; DNA, Neoplasm; Fluorouracil; Histidinol; Imidazoles; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental; Phosphoribosyl Pyrophosphate; RNA, Neoplasm; Uracil Nucleotides	1988
Phase I trial of N-(phosphonacetyl)-L-aspartate, methotrexate, and 5-fluorouracil with leucovorin rescue in patients with advanced cancer. Cancer research, 1989, Aug-15, Volume: 49, Issue:16 Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bone Marrow; Carcinoma, Squamous Cell; Colorectal Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Pentosephosphates; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate	1989
Sequence and schedule-dependent synergy of trimetrexate in combination with 5-fluorouracil in vitro and in mice. Cancer research, 1989, Oct-15, Volume: 49, Issue:20 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cell Survival; Cricetinae; Drug Administration Schedule; Drug Synergism; Fluorouracil; Folic Acid Antagonists; Leukemia P388; Mice; Phosphoribosyl Pyrophosphate; Quinazolines; Trimetrexate	1989
The concentration of 5-phosphoribosyl 1-pyrophosphate in monolayer tumor cells and the effect of various pyrimidine antimetabolites. The International journal of biochemistry, 1985, Volume: 17, Issue:1 Topics: Animals; Aspartic Acid; Cell Line; Cells, Cultured; Fluorouracil; Humans; Methotrexate; Neoplasms; Ornithine Decarboxylase; Orotate Phosphoribosyltransferase; Pentosephosphates; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate	1985
The influence of methotrexate pretreatment on 5-fluorouracil metabolism in L1210 cells. The Journal of biological chemistry, 1981, Feb-25, Volume: 256, Issue:4 Topics: Animals; Biological Transport; Deoxyuridine; Fluorouracil; Kinetics; Leucovorin; Leukemia L1210; Methotrexate; Mice; Phosphoribosyl Pyrophosphate; Purines; RNA, Neoplasm	1981
Optimal schedule of methotrexate and 5-fluorouracil in human breast cancer. Cancer research, 1982, Volume: 42, Issue:5 Topics: Breast Neoplasms; Cell Line; Drug Administration Schedule; Drug Evaluation; Drug Interactions; Drug Synergism; Female; Fluorouracil; Humans; Hypoxanthines; Leucovorin; Leukopenia; Methotrexate; Nausea; Phosphoribosyl Pyrophosphate; Time Factors	1982
Metabolism of 5-fluorouracil in various human normal and tumor tissues. Gan, 1981, Volume: 72, Issue:6 Topics: Adenocarcinoma; Adenosine Triphosphate; Carcinoma, Squamous Cell; Digestive System; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver; Lung; Lung Neoplasms; Neoplasms; Phosphoribosyl Pyrophosphate; Phosphorylation; Ribosemonophosphates	1981
Phosphoribosyl pyrophosphate, pool size and tissue levels as a determinant of 5-fluorouracil response in murine colonic adenocarcinomas. Biochemical pharmacology, 1982, Jun-01, Volume: 31, Issue:11 Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Drug Resistance; Fluorouracil; Leukemia P388; Mice; Neoplasms, Experimental; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Time Factors	1982
Elucidation of pathways of 5-fluorouracil metabolism in xenografts of human colorectal adenocarcinoma. European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:6 Topics: Adenocarcinoma; Allopurinol; Animals; Colonic Neoplasms; Female; Fluorouracil; Humans; Hypoxanthines; Male; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Neoplasms, Experimental; Orotate Phosphoribosyltransferase; Orotic Acid; Phosphoribosyl Pyrophosphate; Rectal Neoplasms; Ribosemonophosphates; Transplantation, Heterologous; Uridine Phosphorylase	1983
Phase-I trial of combination therapy with continuous-infusion MMPR and continuous-infusion 5-FU. Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Fluorouracil; Humans; Inosine; Male; Methylthioinosine; Middle Aged; Neoplasms; Phosphoribosyl Pyrophosphate; RNA, Neoplasm	1984
Mechanism of inhibition of phosphoribosylation of 5-fluorouracil by purines. Biochemical pharmacology, 1984, Sep-15, Volume: 33, Issue:18 Topics: Animals; Cells, Cultured; Fluorouracil; Mice; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Purines	1984
Enhancement of antineoplastic activity of 5-fluorouracil in mice bearing colon 38 tumor by (6R)5,10-dideazatetrahydrofolic acid. Biochemical pharmacology, 1994, Jun-01, Volume: 47, Issue:11 Topics: Acyltransferases; Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Synergism; Female; Fluorouracil; Hydroxymethyl and Formyl Transferases; Mice; Mice, Inbred C57BL; Phosphoribosyl Pyrophosphate; Phosphoribosylglycinamide Formyltransferase; Purine Nucleotides; Tetrahydrofolates	1994
Reduced activity of anabolizing enzymes in 5-fluorouracil-resistant human stomach cancer cells. Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:2 Topics: Antimetabolites, Antineoplastic; DNA, Neoplasm; Drug Resistance; Fluorouracil; Genes; Humans; Phosphoribosyl Pyrophosphate; Polymorphism, Single-Stranded Conformational; RNA, Neoplasm; Stomach Neoplasms; Thymidylate Synthase; Tumor Cells, Cultured	1996
Tiazofurin enhances the anabolism and toxicity of 5-fluorouracil. Cancer letters, 1996, Dec-03, Volume: 109, Issue:1-2 Topics: Animals; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Fluorouracil; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Phosphoribosyl Pyrophosphate; Ribavirin	1996
Pretreatment of colon carcinoma cells with Tomudex enhances 5-fluorouracil cytotoxicity. Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Fluorouracil; Humans; Nucleotides; Phosphoribosyl Pyrophosphate; Quinazolines; RNA, Neoplasm; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured	1998
Mechanisms for 5-fluorouracil resistance in human colon cancer DLD-1 cells. Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:6 Topics: Antimetabolites, Antineoplastic; Cell Count; Colorectal Neoplasms; Drug Resistance, Neoplasm; Floxuridine; Fluorouracil; Humans; Intracellular Fluid; Phosphoribosyl Pyrophosphate; RNA, Neoplasm; Thymidylate Synthase; Tumor Cells, Cultured; Uridine	1998
Circumvention of 5-fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction. Japanese journal of cancer research : Gann, 1999, Volume: 90, Issue:3 Topics: Adenoviridae; Cytosol; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Escherichia coli; Fluorouracil; Genes, Reporter; Genetic Therapy; Genetic Vectors; Humans; Inhibitory Concentration 50; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Recombinant Proteins; Stomach Neoplasms; Transduction, Genetic; Transfection; Tumor Cells, Cultured; Uracil Nucleotides	1999
Uracil salvage pathway in PC12 cells. Biochimica et biophysica acta, 2001, Nov-15, Volume: 1524, Issue:1 Topics: Animals; Carbon Radioisotopes; Cell Extracts; Fluorouracil; Models, Chemical; PC12 Cells; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Rats; Uracil	2001
Activation pathways of 5-fluorouracil in rat organs and in PC12 cells. Biochemical pharmacology, 2001, Jul-15, Volume: 62, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Fluorouracil; Male; PC12 Cells; Phosphoribosyl Pyrophosphate; Rats; Rats, Sprague-Dawley; Tissue Extracts	2001
Pathways for alpha-D-ribose utilization for nucleobase salvage and 5-fluorouracil activation in rat brain. Biochemical pharmacology, 2002, Jan-15, Volume: 63, Issue:2 Topics: Adenine; Animals; Antimetabolites; Brain; Fluorouracil; In Vitro Techniques; Male; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Rats, Sprague-Dawley; Ribose; Uracil	2002
The purine nucleoside cycle in cell-free extracts of rat brain: evidence for the occurrence of an inosine and a guanosine cycle with distinct metabolic roles. Cellular and molecular life sciences : CMLS, 2003, Volume: 60, Issue:4 Topics: Animals; Brain; Fluorouracil; Guanosine; Inosine; Male; Phosphoribosyl Pyrophosphate; Purine Nucleosides; Pyrimidines; Rats; Rats, Sprague-Dawley; Ribosemonophosphates	2003
Substrate inhibition of uracil phosphoribosyltransferase by uracil can account for the uracil growth sensitivity of Leishmania donovani pyrimidine auxotrophs. The Journal of biological chemistry, 2013, Oct-11, Volume: 288, Issue:41 Topics: Cations, Divalent; Chromatography, Gel; Enzyme Stability; Feedback, Physiological; Fluorouracil; Hydrogen-Ion Concentration; Kinetics; Leishmania donovani; Mutation; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Protein Multimerization; Protozoan Proteins; Pyrimidines; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Temperature; Thiouracil; Uracil	2013
Increase of PRPP enhances chemosensitivity of PRPS1 mutant acute lymphoblastic leukemia cells to 5-Fluorouracil. Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:12 Topics: Animals; Apoptosis; Cell Survival; DNA Damage; Fluorouracil; Gene Expression Regulation, Leukemic; Heterografts; Humans; Jurkat Cells; Lentivirus; Mice; Phosphoribosyl Pyrophosphate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ribose-Phosphate Pyrophosphokinase	2018