phosphoramidite and trifluoromethanesulfonic-acid

phosphoramidite has been researched along with trifluoromethanesulfonic-acid* in 2 studies

Other Studies

2 other study(ies) available for phosphoramidite and trifluoromethanesulfonic-acid

Article	Year
Scaleable and efficient synthesis of 2'-deoxy-2'-N-phthaloyl nucleoside phosphoramidites for oligonucleotide synthesis. Bioorganic & medicinal chemistry letters, 2002, Nov-18, Volume: 12, Issue:22 2'-Deoxy-2'-N-phthaloyl nucleosides were prepared from arabino nucleosides by triflate displacement with phthalimide in the presence of DBU. The corresponding phosphoramidites suitable for automated oligonucleotide synthesis were also synthesized. The scalability of described procedures was demonstrated on a 100-g scale preparation of 2'-deoxy-2'-amino-C phosphoramidite. Topics: Arabinonucleosides; Chemistry, Pharmaceutical; Mesylates; Oligonucleotides; Organophosphorus Compounds; Puromycin Aminonucleoside	2002
An efficient synthesis of nucleotides via the phosphoramidite method using a triflic acid salt of an imidazole-related compound as a promoter. Nucleic acids symposium series, 2000, Issue:44 N-Phenylimidazolium triflate and N-methylbenzimidazolium triflate, new imidazole-related compound/triflic acid-complex type of promoters in the phosphoramidite method, has been developed. These reagents are, particularly, useful for internucleotide-bond formation with lowly reactive reactants and have allowed an efficient, high-yield synthesis of oligodeoxyribonucleotides both in a solution phase and on a solid supports. Topics: Imidazoles; Indicators and Reagents; Mesylates; Methods; Molecular Structure; Oligodeoxyribonucleotides; Organophosphorus Compounds	2000

Article

Year

Scaleable and efficient synthesis of 2'-deoxy-2'-N-phthaloyl nucleoside phosphoramidites for oligonucleotide synthesis.

Bioorganic & medicinal chemistry letters, 2002, Nov-18, Volume: 12, Issue:22

2'-Deoxy-2'-N-phthaloyl nucleosides were prepared from arabino nucleosides by triflate displacement with phthalimide in the presence of DBU. The corresponding phosphoramidites suitable for automated oligonucleotide synthesis were also synthesized. The scalability of described procedures was demonstrated on a 100-g scale preparation of 2'-deoxy-2'-amino-C phosphoramidite.

Topics: Arabinonucleosides; Chemistry, Pharmaceutical; Mesylates; Oligonucleotides; Organophosphorus Compounds; Puromycin Aminonucleoside

2002

An efficient synthesis of nucleotides via the phosphoramidite method using a triflic acid salt of an imidazole-related compound as a promoter.

Nucleic acids symposium series, 2000, Issue:44

N-Phenylimidazolium triflate and N-methylbenzimidazolium triflate, new imidazole-related compound/triflic acid-complex type of promoters in the phosphoramidite method, has been developed. These reagents are, particularly, useful for internucleotide-bond formation with lowly reactive reactants and have allowed an efficient, high-yield synthesis of oligodeoxyribonucleotides both in a solution phase and on a solid supports.

Topics: Imidazoles; Indicators and Reagents; Mesylates; Methods; Molecular Structure; Oligodeoxyribonucleotides; Organophosphorus Compounds

2000