phosphoramidite has been researched along with sulfamic-acid* in 1 studies
1 other study(ies) available for phosphoramidite and sulfamic-acid
| Article | Year |
|---|---|
Catalytic enantioselective addition of organometallic reagents to N-formylimines using monodentate phosphoramidite ligands.
The asymmetric synthesis of protected amines via the copper/phosphoramidite-catalyzed addition of organozinc and organoaluminum reagents to N-acylimines, generated in situ from aromatic and aliphatic alpha-amidosulfones, is reported. High yields of optically active N-formyl-protected amines and enantioselectivities up to 99% were obtained. Under the reaction conditions, partial oxidation of the phosphoramidite ligand to the corresponding phosphoric amide was detected. A preliminary study on the origin and the effect on the catalytic addition reaction is presented. Topics: Catalysis; Copper; Formates; Imines; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Organometallic Compounds; Organophosphorus Compounds; Oxidation-Reduction; Stereoisomerism; Sulfonic Acids; Sulfonium Compounds; Toluene | 2008 |