phosphoramidite and diethylenetriamine

phosphoramidite has been researched along with diethylenetriamine* in 1 studies

Other Studies

1 other study(ies) available for phosphoramidite and diethylenetriamine

Article	Year
Formation of N-branched oligonucleotides as by-products in solid-phase oligonucleotide synthesis. Oligonucleotides, 2006,Summer, Volume: 16, Issue:2 During the synthesis of oligonucleotides by the standard phosphoramidite method using 2'-deoxycytidine- derivatized solid support, a side reaction was observed that gave rise to the formation of high molecular weight N-branched oligomers having two identical chains linked to the 3'-terminal 2'-deoxycytidine. Postsynthesis treatment with neat triethylamine trihydrofluoride selectively cleaved the phosphoramidate linkage and converted the N-branched oligomers back to the expected oligonucleotides. Topics: Base Sequence; Deoxycytidine; Oligonucleotides; Organophosphorus Compounds; Polyamines	2006

Article

Year

Formation of N-branched oligonucleotides as by-products in solid-phase oligonucleotide synthesis.

Oligonucleotides, 2006,Summer, Volume: 16, Issue:2

During the synthesis of oligonucleotides by the standard phosphoramidite method using 2'-deoxycytidine- derivatized solid support, a side reaction was observed that gave rise to the formation of high molecular weight N-branched oligomers having two identical chains linked to the 3'-terminal 2'-deoxycytidine. Postsynthesis treatment with neat triethylamine trihydrofluoride selectively cleaved the phosphoramidate linkage and converted the N-branched oligomers back to the expected oligonucleotides.

Topics: Base Sequence; Deoxycytidine; Oligonucleotides; Organophosphorus Compounds; Polyamines

2006