phosphoramidite and cyclooctane

phosphoramidite has been researched along with cyclooctane* in 1 studies

Other Studies

1 other study(ies) available for phosphoramidite and cyclooctane

Article	Year
Synthesis of oligoribonucleic acid conjugates using a cyclooctyne phosphoramidite. Organic letters, 2010, Dec-03, Volume: 12, Issue:23 The conjugation of a ribonucleic acid 16-mer with the cationic amphiphilic peptide penetratin and an anionic hyaluronan tetrasaccharide by means of Cu-free "click" chemistry is reported. The alkyne-functionalized 16-mer was prepared by automated solid-phase synthesis, using a newly developed strained cyclooctyne phosphoramidite in the final coupling. Cycloaddition of the alkyne functionalized RNA to the azide containing biomolecules led to a clean conversion into the corresponding nucleic acid conjugates. Topics: Cyclooctanes; Molecular Structure; Organophosphorus Compounds; RNA	2010

Article

Year

Synthesis of oligoribonucleic acid conjugates using a cyclooctyne phosphoramidite.

Organic letters, 2010, Dec-03, Volume: 12, Issue:23

The conjugation of a ribonucleic acid 16-mer with the cationic amphiphilic peptide penetratin and an anionic hyaluronan tetrasaccharide by means of Cu-free "click" chemistry is reported. The alkyne-functionalized 16-mer was prepared by automated solid-phase synthesis, using a newly developed strained cyclooctyne phosphoramidite in the final coupling. Cycloaddition of the alkyne functionalized RNA to the azide containing biomolecules led to a clean conversion into the corresponding nucleic acid conjugates.

Topics: Cyclooctanes; Molecular Structure; Organophosphorus Compounds; RNA

2010