phosphoramidite and 2-5-dimethylfuran

phosphoramidite has been researched along with 2-5-dimethylfuran* in 1 studies

Other Studies

1 other study(ies) available for phosphoramidite and 2-5-dimethylfuran

ArticleYear
Easy introduction of maleimides at different positions of oligonucleotide chains for conjugation purposes.
    Organic & biomolecular chemistry, 2012, Nov-14, Volume: 10, Issue:42

    [2,5-Dimethylfuran]-protected maleimides were placed at both internal positions and the 3'-end of oligonucleotides making use of solid-phase synthesis procedures. A new phosphoramidite derivative and a new solid support incorporating the protected maleimide moiety were prepared for this purpose. In all cases maleimide deprotection (retro-Diels-Alder reaction) followed by reaction with thiol-containing compounds afforded the target conjugate.

    Topics: Furans; Maleimides; Oligonucleotides; Organophosphorus Compounds; Solid-Phase Synthesis Techniques; Sulfhydryl Compounds

2012