phosphoramidite has been researched along with 1-1--binaphthyl* in 1 studies
1 other study(ies) available for phosphoramidite and 1-1--binaphthyl
| Article | Year |
|---|---|
Synthesis and application of modular phosphine-phosphoramidite ligands in asymmetric hydroformylation: structure-selectivity relationship.
A series of hybrid phosphine-phosphoramidite ligands has been designed and synthesized in moderate yields from chiral BINOL (1,1'-bi-2-naphthol) or NOBIN (2-amino-2'-hydroxy-1,1'-binaphthyl). They have achieved highly regio- and enantioselectivities in Rh-catalyzed asymmetric hydroformylations of styrene derivatives (branched/linear ratio up to 56.6, ee up to 99 %), vinyl acetate derivatives (up to 98 % ee), and allyl cyanide (up to 96 % ee). Systematic variation of ligand structure showed that the steric factor on the phsophoramidite moiety determined the performance of the ligand. With the increased hindrance, the branched/linear ratio rose, while the ee value dropped in the hydroformylation of styrene. However, the N-substituents did not influence the selectivities much. Topics: Catalysis; Ligands; Naphthalenes; Naphthols; Nitriles; Organophosphorus Compounds; Phosphines; Rhodium; Stereoisomerism; Structure-Activity Relationship; Styrene; Vinyl Compounds | 2010 |