phosphoramidic acid has been researched along with stavudine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 13 (81.25) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balzarini, J; Bidois, L; Cahard, D; De Clercq, E; McGuigan, C; Naesens, L; Salgado, A; Tsang, HW; Turner, K; Velazquez, S | 1 |
| Ballatore, C; Balzarini, J; De Clercq, E; Gilbert, IH; McGuigan, C; Siddiqui, AQ; Zuccotto, F | 1 |
| Ballatore, C; Balzarini, J; Bidois, L; De Clercq, E; Hiouni, A; McGuigan, C | 1 |
| Balzarini, J; Cahard, D; Gilbert, IH; Harris, SA; Heshmati, P; Knaggs, MH; McGuigan, C | 1 |
| Gumbleton, M; Kandalaft, LE; McGuigan, C; Siccardi, D | 1 |
| Pendergrass, S; Qazi, S; Samuel, P; Uckun, FM; Venkatachalam, TK | 1 |
| Gumbleton, M; McGuigan, C; Omidi, Y; Siccardi, D | 1 |
| Li, G; Mao, C; Pendergrass, S; Qazi, S; Samuel, P; Uckun, FM; Venkatachalam, TK | 1 |
| Pendergrass, S; Qazi, S; Samuel, P; Uckun, FM; Venkatachalam, TK; Yu, G | 1 |
| Samuel, P; Uckun, FM; Venkatachalam, TK | 2 |
| Qazi, S; Samuel, P; Uckun, FM; Venkatachalam, TK | 2 |
| Qazi, S; Uckun, FM; Venkatachalam, TK | 1 |
| Qazi, S; Sarquis, M; Uckun, FM; Venkatachalam, TK | 1 |
| Gong, S; Li, X; Liu, G; Peng, L; Shen, L; Sun, Q | 1 |
16 other study(ies) available for phosphoramidic acid and stavudine
| Article | Year |
|---|---|
Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation.
Topics: Amides; Amino Acids; Animals; Cell Line; HIV; HIV-1; HIV-2; Humans; Mice; Organophosphates; Organophosphorus Compounds; Phosphoric Acids; Stavudine; Structure-Activity Relationship; Thymidine Kinase | 1997 |
Design and synthesis of lipophilic phosphoramidate d4T-MP prodrugs expressing high potency against HIV in cell culture: structural determinants for in vitro activity and QSAR.
Topics: Amides; Anti-HIV Agents; Cell Line; Dideoxynucleotides; HIV-1; HIV-2; Phosphoric Acids; Prodrugs; Stavudine; Structure-Activity Relationship | 1999 |
Phosphoramidate derivatives of stavudine as inhibitors of HIV: unnatural amino acids may substitute for alanine.
Topics: Alanine; Amides; Amino Acid Substitution; Amino Acids; Anti-HIV Agents; Cell Line; HIV-1; HIV-2; Humans; Phosphoric Acids; Reverse Transcriptase Inhibitors; Stavudine; Structure-Activity Relationship | 2000 |
A QSAR study investigating the effect of L-alanine ester variation on the anti-HIV activity of some phosphoramidate derivatives of d4T.
Topics: Alanine; Amides; Anti-HIV Agents; Cell Death; HIV-1; HIV-2; Models, Chemical; Models, Molecular; Phosphoric Acids; Quantitative Structure-Activity Relationship; Stavudine; Structure-Activity Relationship | 2000 |
Stereoselective and concentration-dependent polarized epithelial permeability of a series of phosphoramidate triester prodrugs of d4T: an in vitro study in Caco-2 and Madin-Darby canine kidney cell monolayers.
Topics: Amides; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Calcium Channel Blockers; Carboxylic Ester Hydrolases; Cattle; Cell Membrane Permeability; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Dogs; Epithelial Cells; Humans; Kidney; Mass Spectrometry; Phosphoric Acids; Prodrugs; Solubility; Spectrophotometry, Ultraviolet; Stavudine; Stereoisomerism; Verapamil | 2003 |
Phenyl phosphoramidate derivatives of stavudine as anti-HIV agents with potent and selective in-vitro antiviral activity against adenovirus.
Topics: Adenoviridae; Adenoviridae Infections; Amides; Anti-HIV Agents; Antiviral Agents; Enzyme Inhibitors; HIV Infections; HIV-1; Humans; In Vitro Techniques; Phosphoric Acids; Stavudine; Structure-Activity Relationship; Zidovudine | 2004 |
Stereospecific chemical and enzymatic stability of phosphoramidate triester prodrugs of d4T in vitro.
Topics: Amides; Animals; Anti-HIV Agents; Caco-2 Cells; Chromatography, High Pressure Liquid; Esters; Humans; Hydrolysis; In Vitro Techniques; Liver; Male; Phosphoric Acids; Prodrugs; Rats; Rats, Wistar; Stavudine; Stereoisomerism; Time Factors | 2004 |
Lipase-mediated stereoselective hydrolysis of stampidine and other phosphoramidate derivatives of stavudine.
Topics: Amides; Antiviral Agents; Candida; Chromatography, High Pressure Liquid; Dideoxynucleotides; Esterases; Hydrolysis; Inhibitory Concentration 50; Lipase; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Phosphoric Acids; Protein Conformation; Stavudine; Stereoisomerism; Thymidine Monophosphate | 2004 |
A comparative study of the hydrolysis pathways of substituted aryl phosphoramidate versus aryl thiophosphoramidate derivatives of stavudine.
Topics: Amides; Animals; Cells, Cultured; Humans; Hydrolysis; Phosphates; Phosphoric Acids; Stavudine; Swine | 2004 |
Stereochemical influence on lipase-mediated hydrolysis and biological activity of stampidine and other stavudine phosphoramidates.
Topics: Amides; Chromatography, High Pressure Liquid; Dideoxynucleotides; Humans; Hydrolysis; In Vitro Techniques; Lipase; Magnetic Resonance Spectroscopy; Models, Molecular; Phosphoric Acids; Reverse Transcriptase Inhibitors; Spectrophotometry, Ultraviolet; Stavudine; Stereoisomerism; T-Lymphocytes; Thymidine Monophosphate | 2005 |
Enzymatic hydrolysis of stampidine and other stavudine phosphoramidates in the presence of mammalian proteases.
Topics: Amides; Animals; Cathepsin B; Cattle; Dideoxynucleotides; Endopeptidase K; Hydrolysis; Kinetics; Molecular Structure; Peptide Hydrolases; Phosphoric Acids; Stavudine; Thymidine Monophosphate | 2005 |
Protease-mediated enzymatic hydrolysis and activation of aryl phosphoramidate derivatives of stavudine.
Topics: Amides; Biotransformation; Dideoxynucleotides; Magnetic Resonance Spectroscopy; Peptide Hydrolases; Phosphoric Acids; Prodrugs; Spectrophotometry, Ultraviolet; Stavudine; Stereoisomerism; Thymidine Monophosphate | 2005 |
Effect of change in nucleoside structure on the activation and antiviral activity of phosphoramidate derivatives.
Topics: Amides; Animals; Anti-HIV Agents; Cell Line, Tumor; Dideoxynucleotides; Enzyme Inhibitors; Esterases; Humans; Kinetics; Lipase; Lymphocytes; Microbial Sensitivity Tests; Molecular Conformation; Peptide Hydrolases; Phenol; Phosphoric Acids; Stavudine; Stereoisomerism; Structure-Activity Relationship; Thymidine Monophosphate; Zidovudine | 2005 |
Synthesis and metabolism of naphthyl substituted phosphoramidate derivatives of stavudine.
Topics: Amides; Carica; Esterases; Hydrolysis; Lipase; Molecular Structure; Naphthalenes; Phosphoric Acids; Serine Endopeptidases; Stavudine; Stereoisomerism; Subtilisins; Time Factors | 2006 |
Effect of alkyl groups on the cellular hydrolysis of stavudine phosphoramidates.
Topics: Amides; Animals; Binding Sites; Cell Line; Chlorocebus aethiops; COS Cells; Esterases; Humans; Hydrolysis; Jurkat Cells; Lipase; Mice; Molecular Structure; Peptide Hydrolases; Phosphoric Acids; Stavudine | 2006 |
A novel synthesis of antiviral nucleoside phosphoramidate and thiophosphoramidate prodrugs via nucleoside H-phosphonamidates.
Topics: Amides; Antiviral Agents; Magnetic Resonance Spectroscopy; Nucleosides; Organothiophosphorus Compounds; Phosphoric Acids; Prodrugs; Pyrimidine Nucleosides; Stavudine; Zidovudine | 2013 |