Page last updated: 2024-08-24

phosphoramidic acid and oligonucleotides

phosphoramidic acid has been researched along with oligonucleotides in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19903 (3.95)18.7374
1990's10 (13.16)18.2507
2000's43 (56.58)29.6817
2010's14 (18.42)24.3611
2020's6 (7.89)2.80

Authors

AuthorsStudies
Ikehara, M; Miyake, T; Ohtsuka, E1
Durrant, I; Evans, MR; Fowler, SJ; Gait, MJ; Misiura, K1
Biancotto, G; Bonora, GM; Scremin, CL1
Kitamura, M; Ozaki, H; Shimidzu, T; Yamana, K1
Berner, S; Mühlegger, K; Seliger, H1
Connolly, BA; Eckstein, F1
Chen, JK; DeDionisio, LA; Gryaznov, SM; Lloyd, DH; Ratmeyer, L; Schultz, RG; Wilson, WD1
Bailey, M; Davidson, BE; Hagmar, P; Haralambidis, J; Sawyer, WH; Tong, G1
Barthet, C; Bidan, G; Dejean, E; Livache, T; Roget, A; Téoule, R1
Garman, AJ; Hardy, PM; Holland, D; McLean, MJ; Newton, CR; Scott, S1
Barsky, D; Colvin, ME; Gryaznov, SM; Zon, G1
Krzymanska-Olejnik, E; Olejnik, J; Rothschild, KJ1
Egli, M; Gryaznov, SM1
Torigoe, H2
Fidanza, JA; McGall, GH1
Cantor, CR; Denissenko, MF; Leppin, AL; Rodi, CP; Shchepinov, MS; Smylie, KJ; Wörl, RJ1
Abbas, S; Bertram, RD; Hayes, CJ1
Iwai, S1
Ghosh, K; Lyer, RP; Roland, A; Zhou, W1
Gietzen, K; Gryaznov, S; Pongracz, K; Pruzan, R; Wallweber, G1
Gryaznov, SM; Herbert, BS; Pongracz, K; Shay, JW; Shea-Herbert, B1
Eschenmoser, A; Ferencic, M; Guntha, S; Krishnamurthy, R; Wu, X1
Andoh, J; Imanishi, T; Koizumi, M; Morita, K; Obika, S; Onoda, M1
Akaike, T; Maruyama, A; Torigoe, H1
Kim, BH; Kim, SJ; Venkatesan, N1
Akinaga, S; Asai, A; Chin, AC; Gryaznov, S; Harley, CB; Kusaka, H; Li, S; Oshima, Y; Piatyszek, M; Pongracz, K; Pruzan, R; Uochi, TA; Wunder, E; Yamamoto, Y; Yamashita, Y1
Pon, RT; Yu, S1
Hari, Y; Hiroto, A; Imanishi, T; Nakagawa, O; Obika, S1
Akiyama, M; Anderson, KC; Gryaznov, S; Hamasaki, M; Hayashi, T; Hideshima, T; Munshi, NC; Richardson, P; Shammas, MA; Tai, YT1
Debart, F; Geinguenaud, F; Michel, T; Taillandier, E; Vasseur, JJ1
Cao, C; Ichikawa, Y; Jiang, YL; Song, F; Stivers, JT1
Bowen, LM; Dupureur, CM; King, JB1
Larson, JD; Sumanas, S1
Abramova, TV; Silnikov, VN; Vasilyeva, SV1
Imanishi, T; Obika, S; Sekiguchi, M; Somjing, R1
Maruyama, A; Torigoe, H1
Debart, F; Heitz, F; Michel, T; Vasseur, JJ1
Endo, M; Majima, T1
Busson, R; Herdewijn, P; Lagoja, IM; Rozenski, J; Van Aerschot, A; Zhou, D1
Dupureur, CM1
Eschenmoser, A; Ferencic, M; Guntha, S; Krishnamurthy, R; Nandy, J; Reddy, G; Wu, X1
Dikmen, ZG; Gryaznov, SM; Jackson, SR; Paulson, V; Shay, JW; Watkins, L; Wright, WE; Zhu, CH1
Imanishi, T; Nakagawa, O; Negoro, Y; Obika, S; Orita, A; Tomizu, M1
Dikmen, ZG; Gryaznov, SM; Shay, JW; Wright, WE1
Böge, N; Meier, C; Szombati, Z1
Huang, Z; Sheng, J1
Carriero, S; Damha, MJ1
Johnson, DC; Widlanski, TS1
Morocho, AM; Polushin, NN1
Heckel, A1
Abramov, M; Herdewijn, P1
Hovinen, J; Jaakkola, L; Ylikoski, A1
Meyer, A; Morvan, F; Vasseur, JJ1
Abes, R; Abes, S; Chernomordik, LV; Clair, P; Iversen, PL; Lebleu, B; Melikov, K; Moulton, HM; Prevot, P; Yang, ST; Youngblood, DS1
Köstler, K; Rosemeyer, H1
Cosstick, R; Fisher, J; Gaynor, JW; Piperakis, MM1
Gryaznov, SM1
Hosoki, N; Imanishi, T; Ito, KR; Kodama, T; Makimura, F; Obika, S; Orita, A; Osaki, T1
Chen, YH; Hwang, CC; Ko, NC; Severance, S; Shih, YT; Su, YC; Wang, EC; Wang, TP; Wu, MH1
Hwang, CC; Lo, YL; Su, YC; Wang, EC; Wang, LF; Wang, TP; Wang, YM; Wu, MH1
Caruthers, MH; Monfregola, L; Paul, S; Roy, S; Shang, S; Shoemaker, R1
Haug, R; Kalinowski, M; Kramer, M; Piasecka, S; Richert, C; Said, H1
Caruthers, MH; Kosbar, T; Paul, S; Vejlegaard, K; Wengel, J1
Damha, MJ; Vlaho, D1
Appel, B; Müller, S; Suchsland, R1
Altman, S; Burakova, EA; Chelobanov, BP; Fokina, AA; Miroshnichenko, SK; Patutina, OA; Stetsenko, DA; Vlassov, VV; Zenkova, MA1
Kostov, O; Liboska, R; Novák, P; Páv, O; Rosenberg, I1
Gryaznov, SM; Pourshahian, S1
Izgu, EC; Lelyveld, VS; O'Flaherty, DK; Szostak, JW; Zhou, L1
Abramov, M; Eremeeva, E; Herdewijn, P; Nguyen, H1
Lelyveld, VS; Szostak, JW; Zhang, W1
Srivatsan, SG; Walunj, MB1
Äärelä, A; Aho, A; Korhonen, H; Österlund, T; Tähtinen, V; Virta, P1
Beigelman, L; De Costa, NTS; Gryaznov, SM; Hong, J; Martínez-Montero, S; Pandey, RK; Pourshahian, S; Rajwanshi, VK1
Khodyreva, SN; Kupryushkin, MS; Markov, OV; Mironova, EM; Zharkov, TD; Zhukov, SA1

Reviews

6 review(s) available for phosphoramidic acid and oligonucleotides

ArticleYear
Synthetic oligonucleotides as RNA mimetics: 2'-modified Rnas and N3'-->P5' phosphoramidates.
    Cellular and molecular life sciences : CMLS, 2000, Volume: 57, Issue:10

    Topics: Amides; Animals; Humans; Molecular Mimicry; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; RNA

2000
Modified oligonucleotides--synthesis, properties and applications.
    Current opinion in molecular therapeutics, 1999, Volume: 1, Issue:3

    Topics: Amides; Boron Compounds; Carbohydrates; Drug Design; Molecular Conformation; Molecular Structure; Oligonucleotides; Peptide Nucleic Acids; Phosphoric Acids; Purines; Pyrimidines; Stereoisomerism; Structure-Activity Relationship; Thionucleotides

1999
Novel phosphoramidite building blocks in synthesis and applications toward modified oligonucleotides.
    Current medicinal chemistry, 2003, Volume: 10, Issue:19

    Topics: Amides; Molecular Structure; Nucleic Acid Conformation; Nucleic Acids; Oligonucleotides; Phosphoric Acids

2003
Morpholino phosphorodiamidate oligonucleotides in zebrafish: a recipe for functional genomics?
    Briefings in functional genomics & proteomics, 2002, Volume: 1, Issue:3

    Topics: Amides; Animals; Genomics; Models, Genetic; Oligonucleotides; Phosphoric Acids; RNA Splicing; Zebrafish

2002
Overview of the synthesis of nucleoside phosphates and polyphosphates.
    Current protocols in nucleic acid chemistry, 2004, Volume: Chapter 13

    Topics: Amides; Anhydrides; Catalysis; Models, Biological; Nucleosides; Nucleotides; Oligonucleotides; Organophosphonates; Phosphates; Phosphoadenosine Phosphosulfate; Phosphoric Acids; Phosphorus; Phosphorylation; Polyphosphates

2004
Oligonucleotide n3'-->p5' phosphoramidates and thio-phoshoramidates as potential therapeutic agents.
    Chemistry & biodiversity, 2010, Volume: 7, Issue:3

    Topics: Amides; Antineoplastic Agents; DNA; Humans; Oligonucleotides; Oligonucleotides, Antisense; Phosphoric Acids; RNA; Telomerase

2010

Other Studies

70 other study(ies) available for phosphoramidic acid and oligonucleotides

ArticleYear
New phosphoramidates as protecting groups in ribooligonucleotides synthesis.
    Nucleic acids research, 1976, Volume: 3, Issue:3

    Topics: Amides; Chromatography, Paper; Methods; Oligonucleotides; Oligoribonucleotides; Organophosphorus Compounds; Phenylenediamines; Phosphoric Acids; Spectrophotometry, Ultraviolet

1976
Applications of oligonucleotides bearing single and multiple labels introduced during synthesis.
    Nucleic acids symposium series, 1991, Issue:24

    Topics: Amides; Biotin; Fluoresceins; Oligonucleotides; Phosphoric Acids

1991
Use of the amidite chemistry in the PEG-supported, large-scale synthesis of oligonucleotides. The 'HELP Plus' method.
    Nucleic acids symposium series, 1991, Issue:24

    Topics: Amides; Chemistry; Indicators and Reagents; Oligonucleotides; Phosphoric Acids; Polyethylene Glycols

1991
Structure and properties of oligonucleotide analogs having phosphoramidate linkages.
    Nucleic acids symposium series, 1990, Issue:22

    Topics: Amides; Molecular Structure; Oligonucleotides; Phosphoric Acids; Poly A; Thermodynamics

1990
Studies on the role of tetrazole in the activation of phosphoramidites.
    Nucleic acids research, 1989, Feb-11, Volume: 17, Issue:3

    Topics: Amides; Azoles; Magnetic Resonance Spectroscopy; Models, Molecular; Oligonucleotides; Organophosphorus Compounds; Phosphoric Acids; Structure-Activity Relationship; Tetrazoles

1989
Assignment of resonances in the 31P NMR spectrum of d(GGAATTCC) by regiospecific labeling with oxygen-17.
    Biochemistry, 1984, Nov-06, Volume: 23, Issue:23

    Topics: Amides; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Oligonucleotides; Oxygen Isotopes; Phosphates; Phosphoric Acids; Phosphorus

1984
Oligonucleotide N3'-->P5' phosphoramidates.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jun-20, Volume: 92, Issue:13

    Topics: Amides; Base Sequence; Circular Dichroism; DNA; Drug Stability; Indicators and Reagents; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Oligoribonucleotides; Phosphoric Acids; RNA

1995
Synthesis and characterisation of fluorescent oligonucleotides. Effect of internal labelling on protein recognition.
    Biochimica et biophysica acta, 1995, Jun-09, Volume: 1244, Issue:2-3

    Topics: Amides; Base Sequence; Binding Sites; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Fluorescein-5-isothiocyanate; Fluorescence Polarization; Fluorescent Dyes; Macromolecular Substances; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; Repressor Proteins; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship

1995
Preparation of a DNA matrix via an electrochemically directed copolymerization of pyrrole and oligonucleotides bearing a pyrrole group.
    Nucleic acids research, 1994, Aug-11, Volume: 22, Issue:15

    Topics: Amides; Base Sequence; DNA; Electrochemistry; Electrodes; Genes, ras; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; Polymers; Pyrroles

1994
Reagents for the preparation of two oligonucleotides per synthesis (TOPS).
    Nucleic acids research, 1994, Aug-11, Volume: 22, Issue:15

    Topics: alpha 1-Antitrypsin; Amides; Ammonium Hydroxide; Autoanalysis; Base Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; Electrophoresis, Agar Gel; Humans; Hydrogen Bonding; Hydroxides; Indicators and Reagents; Methanol; Methylamines; Molecular Sequence Data; Molecular Structure; Oligonucleotides; Phosphoric Acids; Polymerase Chain Reaction

1994
Hydration effects on the duplex stability of phosphoramidate DNA-RNA oligomers.
    Nucleic acids research, 1997, Feb-15, Volume: 25, Issue:4

    Topics: Amides; DNA; DNA, Single-Stranded; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Quantum Theory; RNA; Water

1997
Photocleavable aminotag phosphoramidites for 5'-termini DNA/RNA labeling.
    Nucleic acids research, 1998, Aug-01, Volume: 26, Issue:15

    Topics: Amides; Chromatography, Affinity; DNA; Evaluation Studies as Topic; Molecular Structure; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; RNA

1998
Thermodynamic and kinetic effects of N3'-->P5' phosphoramidate modification on pyrimidine motif triplex DNA formation.
    Biochemistry, 2001, Jan-30, Volume: 40, Issue:4

    Topics: Amides; Biosensing Techniques; Biotin; Calorimetry; Circular Dichroism; DNA; Electrophoresis, Polyacrylamide Gel; Kinetics; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Organophosphorus Compounds; Phosphoric Acids; Pyrimidines; Spectrophotometry, Ultraviolet; Thermodynamics

2001
Photolithographic synthesis of high-density oligonucleotide arrays.
    Methods in molecular biology (Clifton, N.J.), 2001, Volume: 170

    Topics: 2-Aminopurine; Amides; Combinatorial Chemistry Techniques; Membrane Glycoproteins; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Phosphoric Acids; Photolysis; Purine Nucleosides

2001
Matrix-induced fragmentation of P3'-N5' phosphoramidate-containing DNA: high-throughput MALDI-TOF analysis of genomic sequence polymorphisms.
    Nucleic acids research, 2001, Sep-15, Volume: 29, Issue:18

    Topics: Amides; Deoxycytosine Nucleotides; DNA; Genotype; Humans; Hydrolysis; Oligonucleotides; Phosphoric Acids; Picolinic Acids; Polymorphism, Single Nucleotide; Receptors, Adrenergic, beta-3; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymine Nucleotides

2001
Commercially available 5'-DMT phosphoramidites as reagents for the synthesis of vinylphosphonate-linked oligonucleic acids.
    Organic letters, 2001, Oct-18, Volume: 3, Issue:21

    Topics: Amides; Molecular Structure; Oligonucleotides; Organophosphonates; Organophosphorus Compounds; Phosphoric Acids; Vinyl Compounds

2001
Synthesis and thermodynamic studies of oligonucleotides containing the two isomers of thymine glycol.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2001, Oct-15, Volume: 7, Issue:20

    Topics: Amides; DNA Damage; Drug Stability; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; Stereoisomerism; Temperature; Thermodynamics; Thymine

2001
Allosteric inhibitors of telomerase: oligonucleotide N3'-->P5' phosphoramidates.
    Nucleic acids research, 2002, Jan-15, Volume: 30, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Amides; Animals; Base Sequence; Cell Line; COS Cells; DNA Primers; DNA-Binding Proteins; DNA, Single-Stranded; Humans; Inhibitory Concentration 50; Kinetics; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Oligonucleotides; Oligonucleotides, Antisense; Phosphoric Acids; Recombinant Proteins; RNA; Telomerase; Templates, Genetic; Thermodynamics

2002
Oligonucleotide N3'-->P5' phosphoramidates as efficient telomerase inhibitors.
    Oncogene, 2002, Jan-21, Volume: 21, Issue:4

    Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Cell Division; Enzyme Inhibitors; Female; Humans; Oligonucleotides; Phosphoric Acids; Telomerase; Telomere; Tumor Cells, Cultured

2002
Base-pairing systems related to TNA: alpha-threofuranosyl oligonucleotides containing phosphoramidate linkages.
    Organic letters, 2002, Apr-18, Volume: 4, Issue:8

    Topics: Amides; Base Pairing; Chromatography, High Pressure Liquid; Circular Dichroism; DNA; Furans; Indicators and Reagents; Oligonucleotides; Phosphoric Acids; RNA; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet

2002
3'-amino-2',4'-BNA: novel bridged nucleic acids having an N3'-->P5' phosphoramidate linkage.
    Chemical communications (Cambridge, England), 2001, Oct-07, Issue:19

    Topics: Amides; Bridged-Ring Compounds; DNA; Molecular Structure; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligonucleotides; Phosphoric Acids; Phosphoric Diester Hydrolases; RNA; Snake Venoms

2001
Promotion of triplex formation by N3'-->P5' phosphoramidate modification: thermodynamic and kinetic studies.
    Nucleic acids research. Supplement (2001), 2001, Issue:1

    Topics: Amides; DNA; Kinetics; Oligonucleotides; Phosphoric Acids; Thermodynamics

2001
Synergistic stabilization of triplex by combination of comb-type cationic copolymer and oligo-N3'-->P5' phosphoramidates.
    Nucleic acids research. Supplement (2001), 2001, Issue:1

    Topics: Amides; Cations; Dextrans; DNA; Kinetics; Oligonucleotides; Phosphoric Acids; Polylysine; Pyrimidine Nucleotides

2001
A novel telomerase template antagonist (GRN163) as a potential anticancer agent.
    Cancer research, 2003, Jul-15, Volume: 63, Issue:14

    Topics: Amides; Biological Availability; Cell Survival; Dose-Response Relationship, Drug; Humans; Oligonucleotides; Phosphoric Acids; RNA; Telomerase

2003
Tandem oligonucleotide synthesis using linker (First Base) phosphoramidites.
    Nucleic acids research. Supplement (2001), 2002, Issue:2

    Topics: Amides; Electrophoresis, Capillary; Oligonucleotides; Phosphoric Acids

2002
Synthesis and properties of 5'-amino-2',4'-BNA modified oligonucleotides with P3'-->N5' phosphoramidate linkages.
    Nucleic acids research. Supplement (2001), 2002, Issue:2

    Topics: Amides; Base Sequence; Nucleic Acids; Oligonucleotides; Phosphoric Acids

2002
Effects of oligonucleotide N3'-->P5' thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells.
    Cancer research, 2003, Oct-01, Volume: 63, Issue:19

    Topics: Amides; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Humans; Multiple Myeloma; Oligonucleotides; Phosphoric Acids; RNA; Telomerase; Telomere

2003
FTIR and UV spectroscopy studies of triplex formation between alpha-oligonucleotides with non-ionic phoshoramidate linkages and DNA targets.
    Journal of biomolecular structure & dynamics, 2003, Volume: 21, Issue:3

    Topics: Amides; Animals; Base Sequence; Chromatography, High Pressure Liquid; DNA; Hydrogen-Ion Concentration; Ions; Models, Chemical; Molecular Sequence Data; Oligonucleotides; Phosphoric Acids; Pyrimidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Temperature; Ultraviolet Rays

2003
The merits of bipartite transition-state mimics for inhibition of uracil DNA glycosylase.
    Bioorganic chemistry, 2004, Volume: 32, Issue:4

    Topics: Amides; Binding, Competitive; DNA Glycosylases; DNA Repair; Enzyme Inhibitors; Escherichia coli Proteins; Hydrogen-Ion Concentration; Molecular Mimicry; Oligonucleotides; Phosphoric Acids; Structure-Activity Relationship; Uracil-DNA Glycosidase; Uridine

2004
Binding and conformational analysis of phosphoramidate-restriction enzyme interactions.
    Biochemistry, 2004, Jul-06, Volume: 43, Issue:26

    Topics: Amides; Anisotropy; Binding Sites; Binding, Competitive; Collodion; Deoxyribonucleases, Type II Site-Specific; Dimerization; DNA; DNA Restriction Enzymes; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Ions; Kinetics; Magnetic Resonance Spectroscopy; Metals; Models, Chemical; Nucleic Acids; Oligonucleotides; Phosphoric Acids; Protein Binding; Protein Conformation; Proteins; Spectrometry, Fluorescence; Thermodynamics; Time Factors

2004
Synthesis of monomers bearing at the 2'-position cyanomethoxycarbonyl group for phosphoramidite oligonucleotide synthesis.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:6-7

    Topics: Amides; Nuclear Magnetic Resonance, Biomolecular; Oligonucleotides; Phosphoric Acids; Spectrophotometry, Ultraviolet

2004
Adjustment of the gamma dihedral angle of an oligonucleotide P3'-->N5' phosphoramidate enhances its binding affinity towards complementary strands.
    Angewandte Chemie (International ed. in English), 2005, Mar-18, Volume: 44, Issue:13

    Topics: Amides; Base Sequence; Binding Sites; Hydrolysis; Ligands; Models, Chemical; Nucleic Acid Conformation; Nucleic Acids; Oligonucleotides; Phosphoric Acids; Temperature; Thymine; Time Factors

2005
Synergistic stabilization of nucleic acid assembly by oligo-N3'-->P5' phosphoramidate modification and additions of comb-type cationic copolymers.
    Journal of the American Chemical Society, 2005, Feb-16, Volume: 127, Issue:6

    Topics: Amides; Circular Dichroism; DNA; Electrophoresis; Hydrogen-Ion Concentration; Kinetics; Oligonucleotides; Phosphoric Acids

2005
Highly stable DNA triplexes formed with cationic phosphoramidate pyrimidine alpha-oligonucleotides.
    Chembiochem : a European journal of chemical biology, 2005, Volume: 6, Issue:7

    Topics: Amides; Base Sequence; Circular Dichroism; DNA; Hydrogen-Ion Concentration; Models, Chemical; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Pyrimidines; Temperature; Ultraviolet Rays

2005
Structural arrangement of DNA constrained by a cross-linker.
    Organic & biomolecular chemistry, 2005, Oct-07, Volume: 3, Issue:19

    Topics: Amides; Base Sequence; Circular Dichroism; Cross-Linking Reagents; Disulfides; DNA; Electrophoresis, Polyacrylamide Gel; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Stereoisomerism; Temperature

2005
Synthesis and properties of aminopropyl nucleic acids.
    Chembiochem : a European journal of chemical biology, 2005, Volume: 6, Issue:12

    Topics: Adenine; Amides; Amines; Base Pairing; Nucleic Acid Denaturation; Nucleosides; Oligonucleotides; Phosphoric Acids; Temperature; Thymine

2005
Unique 31P spectral response to the formation of a specific restriction enzyme-DNA complex.
    Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:7

    Topics: Amides; Crystallization; Deoxyribonucleases, Type II Site-Specific; DNA; Fluorescence Resonance Energy Transfer; Magnetic Resonance Spectroscopy; Oligonucleotides; Phosphoric Acids; Phosphorus Isotopes; Reference Standards; Sensitivity and Specificity; Structure-Activity Relationship

2006
Base-pairing systems related to TNA containing phosphoramidate linkages: synthesis of building blocks and pairing properties.
    Chemistry & biodiversity, 2004, Volume: 1, Issue:7

    Topics: Amides; Base Pairing; Cross-Linking Reagents; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Tetroses

2004
Antiadhesive effects of GRN163L--an oligonucleotide N3'->P5' thio-phosphoramidate targeting telomerase.
    Cancer research, 2007, Feb-01, Volume: 67, Issue:3

    Topics: Amides; Animals; Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Line, Tumor; Humans; Lung Neoplasms; Mice; Mice, Nude; Oligonucleotides; Oligopeptides; Phosphoric Acids; RNA; Telomerase; Telomere; Xenograft Model Antitumor Assays

2007
Double-stranded DNA-templated oligonucleotide digestion triggered by triplex formation.
    Chembiochem : a European journal of chemical biology, 2007, Nov-05, Volume: 8, Issue:16

    Topics: Amides; DNA; Hydrogen-Ion Concentration; Hydrolysis; Models, Molecular; Nucleic Acid Conformation; Nucleic Acids; Oligonucleotide Probes; Oligonucleotides; Phosphoric Acids; Sequence Analysis, DNA; Time Factors

2007
Telomerase targeted oligonucleotide thio-phosphoramidates in T24-luc bladder cancer cells.
    Journal of cellular biochemistry, 2008, May-15, Volume: 104, Issue:2

    Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Humans; Oligonucleotides; Oligopeptides; Phosphoric Acids; RNA; Telomerase; Urinary Bladder Neoplasms

2008
Synthesis of DNA-oligonucleotides damaged by arylamine-modified 2'-deoxyguanosine.
    Nucleosides, nucleotides & nucleic acids, 2007, Volume: 26, Issue:6-7

    Topics: Amides; Amines; Aniline Compounds; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Oligonucleotides; Phosphoric Acids

2007
Synthesis of a 4-selenothymidine phosphoramidite and incorporation into oligonucleotides.
    Current protocols in nucleic acid chemistry, 2008, Volume: Chapter 1

    Topics: Amides; Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Selenium; Spectrometry, Mass, Electrospray Ionization; Thymidine

2008
Solid-phase synthesis of branched oligonucleotides.
    Current protocols in nucleic acid chemistry, 2002, Volume: Chapter 4

    Topics: Amides; Combinatorial Chemistry Techniques; DNA, Single-Stranded; Oligonucleotides; Phosphoric Acids; RNA Splicing; RNA, Bacterial

2002
Methoxyoxalamido chemistry in the synthesis of tethered phosphoramidites and functionalized oligonucleotides.
    Current protocols in nucleic acid chemistry, 2006, Volume: Chapter 4

    Topics: Amides; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Oligonucleotides; Phosphoric Acids; Spectrometry, Mass, Electrospray Ionization

2006
Nucleobase-caged phosphoramidites for oligonucleotide synthesis.
    Current protocols in nucleic acid chemistry, 2007, Volume: Chapter 1

    Topics: Amides; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Microscopy, Confocal; Oligonucleotides; Phosphoric Acids

2007
Synthesis of altritol nucleoside phosphoramidites for oligonucleotide synthesis.
    Current protocols in nucleic acid chemistry, 2007, Volume: Chapter 1

    Topics: Amides; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nucleosides; Oligonucleotides; Phosphoric Acids; Sugar Alcohols

2007
Solid-phase oligonucleotide labeling with DOTA.
    Current protocols in nucleic acid chemistry, 2007, Volume: Chapter 14

    Topics: Amides; Heterocyclic Compounds, 1-Ring; Magnetic Resonance Spectroscopy; Oligonucleotides; Phosphoric Acids; Spectrometry, Mass, Electrospray Ionization

2007
A universal and recyclable solid support for oligonucleotide synthesis.
    Current protocols in nucleic acid chemistry, 2007, Volume: Chapter 3

    Topics: Amides; Chromatography, Thin Layer; Esterification; Magnetic Resonance Spectroscopy; Oligonucleotides; Phosphoric Acids

2007
Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies.
    Nucleic acids research, 2008, Volume: 36, Issue:20

    Topics: Amides; Aminocaproic Acid; Arginine; Biological Transport; Endosomes; HeLa Cells; Heparin; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Liposomes; Morpholines; Oligonucleotides; Peptides; Phosphoric Acids; Stereoisomerism; Structure-Activity Relationship

2008
Towards the synthesis of inosine building blocks for the preparation of oligonucleotides with hydrophobic alkyl chains between the nucleotide units.
    Molecules (Basel, Switzerland), 2009, Oct-26, Volume: 14, Issue:11

    Topics: Amides; Hydrochloric Acid; Inosine; Models, Chemical; Molecular Structure; Oligonucleotides; Organophosphorus Compounds; Phosphoric Acids; Stereoisomerism

2009
Reverse-direction (5'-->3') synthesis of oligonucleotides containing a 3'-S-phosphorothiolate linkage and 3'-terminal 3'-thionucleosides.
    Organic & biomolecular chemistry, 2010, Mar-21, Volume: 8, Issue:6

    Topics: Amides; Base Sequence; Chromatography, High Pressure Liquid; Oligonucleotides; Phosphoric Acids; Sulfhydryl Compounds; Thionucleosides

2010
Cleavage of oligonucleotides containing a P3'→N5' phosphoramidate linkage mediated by single-stranded oligonucleotide templates.
    Molecules (Basel, Switzerland), 2011, Dec-20, Volume: 16, Issue:12

    Topics: Amides; Base Sequence; DNA; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Denaturation; Oligonucleotides; Phosphoric Acids; RNA; Templates, Genetic; Thermodynamics; Ultraviolet Rays

2011
Advanced aqueous-phase phosphoramidation reactions for effectively synthesizing peptide-oligonucleotide conjugates trafficked into a human cell line.
    Bioconjugate chemistry, 2012, Dec-19, Volume: 23, Issue:12

    Topics: Amides; Cell Line, Tumor; Cell Survival; Cell-Penetrating Peptides; Disulfides; Flow Cytometry; Humans; Imidazoles; Microscopy, Confocal; Microscopy, Fluorescence; Nucleic Acids; Oligonucleotides; Phosphoric Acids; Protein Transport; Solutions; tat Gene Products, Human Immunodeficiency Virus; Water

2012
Azide-alkyne cycloaddition for universal post-synthetic modifications of nucleic acids and effective synthesis of bioactive nucleic acid conjugates.
    Organic & biomolecular chemistry, 2014, Sep-14, Volume: 12, Issue:34

    Topics: Alkynes; Amides; Azides; Biological Transport; Catalysis; Cell Line; Cell Survival; Click Chemistry; Copper; Cycloaddition Reaction; Epithelial Cells; Humans; Nucleic Acids; Oligonucleotides; Peptides; Phosphoric Acids; Stereoisomerism

2014
Oxidative substitution of boranephosphonate diesters as a route to post-synthetically modified DNA.
    Journal of the American Chemical Society, 2015, Mar-11, Volume: 137, Issue:9

    Topics: Amides; Azides; Boron Compounds; Chemistry Techniques, Synthetic; Dimerization; DNA; Esters; Ethylamines; Iodine; Magnetic Resonance Spectroscopy; Oligonucleotides; Organophosphonates; Oxidation-Reduction; Phosphoric Acids; Stereoisomerism

2015
Phosphoramidate Ligation of Oligonucleotides in Nanoscale Structures.
    Chembiochem : a European journal of chemical biology, 2016, 06-16, Volume: 17, Issue:12

    Topics: Amides; Carbodiimides; Nanostructures; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; RNA, Small Interfering

2016
Oligodeoxynucleotides containing 2'-amino-LNA nucleotides as constrained morpholino phosphoramidate and phosphorodiamidate monomers.
    Bioorganic & medicinal chemistry letters, 2017, 07-15, Volume: 27, Issue:14

    Topics: Amides; DNA; Molecular Dynamics Simulation; Morpholinos; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Oligonucleotides; Phosphoric Acids; Transition Temperature

2017
Synthesis of Chimeric Oligonucleotides Having Modified Internucleotide Linkages via an Automated H-Phosphonate/Phosphoramidite Approach.
    Current protocols in nucleic acid chemistry, 2018, Volume: 73, Issue:1

    Topics: Amides; Automation; Esters; Oligonucleotides; Organophosphonates; Phosphoric Acids; Spectrometry, Mass, Electrospray Ionization

2018
Synthesis of Trinucleotide Building Blocks in Solution and on Solid Phase.
    Current protocols in nucleic acid chemistry, 2018, Volume: 75, Issue:1

    Topics: Amides; Oligonucleotides; Phosphoric Acids; Proton Magnetic Resonance Spectroscopy; Siloxanes; Solutions; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Styrenes

2018
Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 01-22, Volume: 116, Issue:4

    Topics: Amides; Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA; Melanoma, Experimental; Mice; MicroRNAs; Oligonucleotides; Oligonucleotides, Antisense; Phosphates; Phosphoric Acids; Ribonuclease H; RNA

2019
Solid-Phase Synthesis of Phosphorothioate/Phosphonothioate and Phosphoramidate/Phosphonamidate Oligonucleotides.
    Molecules (Basel, Switzerland), 2019, May-15, Volume: 24, Issue:10

    Topics: Amides; Dimerization; Molecular Structure; Oligonucleotides; Phosphates; Phosphoric Acids; Phosphorothioate Oligonucleotides; Solid-Phase Synthesis Techniques

2019
Sequencing of Phosphoramidate Oligonucleotides by Acid Hydrolysis and Mass Spectrometry.
    Analytical chemistry, 2019, 09-03, Volume: 91, Issue:17

    Topics: Amides; Formates; Hydrolysis; Mass Spectrometry; Oligonucleotides; Phosphoric Acids

2019
DNA polymerase activity on synthetic N3'→P5' phosphoramidate DNA templates.
    Nucleic acids research, 2019, 09-26, Volume: 47, Issue:17

    Topics: Amides; Base Sequence; Circular Dichroism; DNA; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Polymerization; RNA; RNA-Directed DNA Polymerase; Templates, Genetic

2019
In Vivo Expression of Genetic Information from Phosphoramidate-DNA.
    Chembiochem : a European journal of chemical biology, 2020, 01-15, Volume: 21, Issue:1-2

    Topics: Amides; DNA; Gene Expression Profiling; Hydrogen-Ion Concentration; Oligonucleotides; Phosphoric Acids; Polymerase Chain Reaction

2020
Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 03-31, Volume: 117, Issue:13

    Topics: Amides; DNA; DNA-Directed DNA Polymerase; Magnetic Resonance Spectroscopy; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Polymerization; RNA

2020
Nucleic Acid Conformation Influences Postsynthetic Suzuki-Miyaura Labeling of Oligonucleotides.
    Bioconjugate chemistry, 2020, 11-18, Volume: 31, Issue:11

    Topics: Amides; Base Sequence; DNA; Fluorescent Dyes; G-Quadruplexes; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Telomere

2020
Immobilized Carbohydrates for Preparation of 3'-Glycoconjugated Oligonucleotides.
    Current protocols in nucleic acid chemistry, 2020, Volume: 83, Issue:1

    Topics: Amides; Carbohydrate Conformation; Carbohydrate Sequence; Carbohydrates; Glycoconjugates; Oligonucleotides; Phosphoric Acids; Spectrum Analysis

2020
New Oligonucleotide 2'-O-Alkyl N3'→P5' (Thio)-Phosphoramidates as Potent Antisense Agents: Physicochemical Properties and Biological Activity.
    Nucleic acid therapeutics, 2023, Volume: 33, Issue:5

    Topics: Amides; Oligonucleotides; Oligonucleotides, Antisense; Phosphoric Acids

2023
Fork- and Comb-like Lipophilic Structures: Different Chemical Approaches to the Synthesis of Oligonucleotides with Multiple Dodecyl Residues.
    International journal of molecular sciences, 2023, Sep-27, Volume: 24, Issue:19

    Topics: Guanidine; Guanidines; Oligonucleotides; Phosphates

2023