phosphoramidic acid has been researched along with oligonucleotides in 76 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (3.95) | 18.7374 |
1990's | 10 (13.16) | 18.2507 |
2000's | 43 (56.58) | 29.6817 |
2010's | 14 (18.42) | 24.3611 |
2020's | 6 (7.89) | 2.80 |
Authors | Studies |
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Ikehara, M; Miyake, T; Ohtsuka, E | 1 |
Durrant, I; Evans, MR; Fowler, SJ; Gait, MJ; Misiura, K | 1 |
Biancotto, G; Bonora, GM; Scremin, CL | 1 |
Kitamura, M; Ozaki, H; Shimidzu, T; Yamana, K | 1 |
Berner, S; Mühlegger, K; Seliger, H | 1 |
Connolly, BA; Eckstein, F | 1 |
Chen, JK; DeDionisio, LA; Gryaznov, SM; Lloyd, DH; Ratmeyer, L; Schultz, RG; Wilson, WD | 1 |
Bailey, M; Davidson, BE; Hagmar, P; Haralambidis, J; Sawyer, WH; Tong, G | 1 |
Barthet, C; Bidan, G; Dejean, E; Livache, T; Roget, A; Téoule, R | 1 |
Garman, AJ; Hardy, PM; Holland, D; McLean, MJ; Newton, CR; Scott, S | 1 |
Barsky, D; Colvin, ME; Gryaznov, SM; Zon, G | 1 |
Krzymanska-Olejnik, E; Olejnik, J; Rothschild, KJ | 1 |
Egli, M; Gryaznov, SM | 1 |
Torigoe, H | 2 |
Fidanza, JA; McGall, GH | 1 |
Cantor, CR; Denissenko, MF; Leppin, AL; Rodi, CP; Shchepinov, MS; Smylie, KJ; Wörl, RJ | 1 |
Abbas, S; Bertram, RD; Hayes, CJ | 1 |
Iwai, S | 1 |
Ghosh, K; Lyer, RP; Roland, A; Zhou, W | 1 |
Gietzen, K; Gryaznov, S; Pongracz, K; Pruzan, R; Wallweber, G | 1 |
Gryaznov, SM; Herbert, BS; Pongracz, K; Shay, JW; Shea-Herbert, B | 1 |
Eschenmoser, A; Ferencic, M; Guntha, S; Krishnamurthy, R; Wu, X | 1 |
Andoh, J; Imanishi, T; Koizumi, M; Morita, K; Obika, S; Onoda, M | 1 |
Akaike, T; Maruyama, A; Torigoe, H | 1 |
Kim, BH; Kim, SJ; Venkatesan, N | 1 |
Akinaga, S; Asai, A; Chin, AC; Gryaznov, S; Harley, CB; Kusaka, H; Li, S; Oshima, Y; Piatyszek, M; Pongracz, K; Pruzan, R; Uochi, TA; Wunder, E; Yamamoto, Y; Yamashita, Y | 1 |
Pon, RT; Yu, S | 1 |
Hari, Y; Hiroto, A; Imanishi, T; Nakagawa, O; Obika, S | 1 |
Akiyama, M; Anderson, KC; Gryaznov, S; Hamasaki, M; Hayashi, T; Hideshima, T; Munshi, NC; Richardson, P; Shammas, MA; Tai, YT | 1 |
Debart, F; Geinguenaud, F; Michel, T; Taillandier, E; Vasseur, JJ | 1 |
Cao, C; Ichikawa, Y; Jiang, YL; Song, F; Stivers, JT | 1 |
Bowen, LM; Dupureur, CM; King, JB | 1 |
Larson, JD; Sumanas, S | 1 |
Abramova, TV; Silnikov, VN; Vasilyeva, SV | 1 |
Imanishi, T; Obika, S; Sekiguchi, M; Somjing, R | 1 |
Maruyama, A; Torigoe, H | 1 |
Debart, F; Heitz, F; Michel, T; Vasseur, JJ | 1 |
Endo, M; Majima, T | 1 |
Busson, R; Herdewijn, P; Lagoja, IM; Rozenski, J; Van Aerschot, A; Zhou, D | 1 |
Dupureur, CM | 1 |
Eschenmoser, A; Ferencic, M; Guntha, S; Krishnamurthy, R; Nandy, J; Reddy, G; Wu, X | 1 |
Dikmen, ZG; Gryaznov, SM; Jackson, SR; Paulson, V; Shay, JW; Watkins, L; Wright, WE; Zhu, CH | 1 |
Imanishi, T; Nakagawa, O; Negoro, Y; Obika, S; Orita, A; Tomizu, M | 1 |
Dikmen, ZG; Gryaznov, SM; Shay, JW; Wright, WE | 1 |
Böge, N; Meier, C; Szombati, Z | 1 |
Huang, Z; Sheng, J | 1 |
Carriero, S; Damha, MJ | 1 |
Johnson, DC; Widlanski, TS | 1 |
Morocho, AM; Polushin, NN | 1 |
Heckel, A | 1 |
Abramov, M; Herdewijn, P | 1 |
Hovinen, J; Jaakkola, L; Ylikoski, A | 1 |
Meyer, A; Morvan, F; Vasseur, JJ | 1 |
Abes, R; Abes, S; Chernomordik, LV; Clair, P; Iversen, PL; Lebleu, B; Melikov, K; Moulton, HM; Prevot, P; Yang, ST; Youngblood, DS | 1 |
Köstler, K; Rosemeyer, H | 1 |
Cosstick, R; Fisher, J; Gaynor, JW; Piperakis, MM | 1 |
Gryaznov, SM | 1 |
Hosoki, N; Imanishi, T; Ito, KR; Kodama, T; Makimura, F; Obika, S; Orita, A; Osaki, T | 1 |
Chen, YH; Hwang, CC; Ko, NC; Severance, S; Shih, YT; Su, YC; Wang, EC; Wang, TP; Wu, MH | 1 |
Hwang, CC; Lo, YL; Su, YC; Wang, EC; Wang, LF; Wang, TP; Wang, YM; Wu, MH | 1 |
Caruthers, MH; Monfregola, L; Paul, S; Roy, S; Shang, S; Shoemaker, R | 1 |
Haug, R; Kalinowski, M; Kramer, M; Piasecka, S; Richert, C; Said, H | 1 |
Caruthers, MH; Kosbar, T; Paul, S; Vejlegaard, K; Wengel, J | 1 |
Damha, MJ; Vlaho, D | 1 |
Appel, B; Müller, S; Suchsland, R | 1 |
Altman, S; Burakova, EA; Chelobanov, BP; Fokina, AA; Miroshnichenko, SK; Patutina, OA; Stetsenko, DA; Vlassov, VV; Zenkova, MA | 1 |
Kostov, O; Liboska, R; Novák, P; Páv, O; Rosenberg, I | 1 |
Gryaznov, SM; Pourshahian, S | 1 |
Izgu, EC; Lelyveld, VS; O'Flaherty, DK; Szostak, JW; Zhou, L | 1 |
Abramov, M; Eremeeva, E; Herdewijn, P; Nguyen, H | 1 |
Lelyveld, VS; Szostak, JW; Zhang, W | 1 |
Srivatsan, SG; Walunj, MB | 1 |
Äärelä, A; Aho, A; Korhonen, H; Österlund, T; Tähtinen, V; Virta, P | 1 |
Beigelman, L; De Costa, NTS; Gryaznov, SM; Hong, J; Martínez-Montero, S; Pandey, RK; Pourshahian, S; Rajwanshi, VK | 1 |
Khodyreva, SN; Kupryushkin, MS; Markov, OV; Mironova, EM; Zharkov, TD; Zhukov, SA | 1 |
6 review(s) available for phosphoramidic acid and oligonucleotides
Article | Year |
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Synthetic oligonucleotides as RNA mimetics: 2'-modified Rnas and N3'-->P5' phosphoramidates.
Topics: Amides; Animals; Humans; Molecular Mimicry; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; RNA | 2000 |
Modified oligonucleotides--synthesis, properties and applications.
Topics: Amides; Boron Compounds; Carbohydrates; Drug Design; Molecular Conformation; Molecular Structure; Oligonucleotides; Peptide Nucleic Acids; Phosphoric Acids; Purines; Pyrimidines; Stereoisomerism; Structure-Activity Relationship; Thionucleotides | 1999 |
Novel phosphoramidite building blocks in synthesis and applications toward modified oligonucleotides.
Topics: Amides; Molecular Structure; Nucleic Acid Conformation; Nucleic Acids; Oligonucleotides; Phosphoric Acids | 2003 |
Morpholino phosphorodiamidate oligonucleotides in zebrafish: a recipe for functional genomics?
Topics: Amides; Animals; Genomics; Models, Genetic; Oligonucleotides; Phosphoric Acids; RNA Splicing; Zebrafish | 2002 |
Overview of the synthesis of nucleoside phosphates and polyphosphates.
Topics: Amides; Anhydrides; Catalysis; Models, Biological; Nucleosides; Nucleotides; Oligonucleotides; Organophosphonates; Phosphates; Phosphoadenosine Phosphosulfate; Phosphoric Acids; Phosphorus; Phosphorylation; Polyphosphates | 2004 |
Oligonucleotide n3'-->p5' phosphoramidates and thio-phoshoramidates as potential therapeutic agents.
Topics: Amides; Antineoplastic Agents; DNA; Humans; Oligonucleotides; Oligonucleotides, Antisense; Phosphoric Acids; RNA; Telomerase | 2010 |
70 other study(ies) available for phosphoramidic acid and oligonucleotides
Article | Year |
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New phosphoramidates as protecting groups in ribooligonucleotides synthesis.
Topics: Amides; Chromatography, Paper; Methods; Oligonucleotides; Oligoribonucleotides; Organophosphorus Compounds; Phenylenediamines; Phosphoric Acids; Spectrophotometry, Ultraviolet | 1976 |
Applications of oligonucleotides bearing single and multiple labels introduced during synthesis.
Topics: Amides; Biotin; Fluoresceins; Oligonucleotides; Phosphoric Acids | 1991 |
Use of the amidite chemistry in the PEG-supported, large-scale synthesis of oligonucleotides. The 'HELP Plus' method.
Topics: Amides; Chemistry; Indicators and Reagents; Oligonucleotides; Phosphoric Acids; Polyethylene Glycols | 1991 |
Structure and properties of oligonucleotide analogs having phosphoramidate linkages.
Topics: Amides; Molecular Structure; Oligonucleotides; Phosphoric Acids; Poly A; Thermodynamics | 1990 |
Studies on the role of tetrazole in the activation of phosphoramidites.
Topics: Amides; Azoles; Magnetic Resonance Spectroscopy; Models, Molecular; Oligonucleotides; Organophosphorus Compounds; Phosphoric Acids; Structure-Activity Relationship; Tetrazoles | 1989 |
Assignment of resonances in the 31P NMR spectrum of d(GGAATTCC) by regiospecific labeling with oxygen-17.
Topics: Amides; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Oligonucleotides; Oxygen Isotopes; Phosphates; Phosphoric Acids; Phosphorus | 1984 |
Oligonucleotide N3'-->P5' phosphoramidates.
Topics: Amides; Base Sequence; Circular Dichroism; DNA; Drug Stability; Indicators and Reagents; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Oligoribonucleotides; Phosphoric Acids; RNA | 1995 |
Synthesis and characterisation of fluorescent oligonucleotides. Effect of internal labelling on protein recognition.
Topics: Amides; Base Sequence; Binding Sites; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Fluorescein-5-isothiocyanate; Fluorescence Polarization; Fluorescent Dyes; Macromolecular Substances; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; Repressor Proteins; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship | 1995 |
Preparation of a DNA matrix via an electrochemically directed copolymerization of pyrrole and oligonucleotides bearing a pyrrole group.
Topics: Amides; Base Sequence; DNA; Electrochemistry; Electrodes; Genes, ras; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; Polymers; Pyrroles | 1994 |
Reagents for the preparation of two oligonucleotides per synthesis (TOPS).
Topics: alpha 1-Antitrypsin; Amides; Ammonium Hydroxide; Autoanalysis; Base Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; Electrophoresis, Agar Gel; Humans; Hydrogen Bonding; Hydroxides; Indicators and Reagents; Methanol; Methylamines; Molecular Sequence Data; Molecular Structure; Oligonucleotides; Phosphoric Acids; Polymerase Chain Reaction | 1994 |
Hydration effects on the duplex stability of phosphoramidate DNA-RNA oligomers.
Topics: Amides; DNA; DNA, Single-Stranded; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Quantum Theory; RNA; Water | 1997 |
Photocleavable aminotag phosphoramidites for 5'-termini DNA/RNA labeling.
Topics: Amides; Chromatography, Affinity; DNA; Evaluation Studies as Topic; Molecular Structure; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; RNA | 1998 |
Thermodynamic and kinetic effects of N3'-->P5' phosphoramidate modification on pyrimidine motif triplex DNA formation.
Topics: Amides; Biosensing Techniques; Biotin; Calorimetry; Circular Dichroism; DNA; Electrophoresis, Polyacrylamide Gel; Kinetics; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Organophosphorus Compounds; Phosphoric Acids; Pyrimidines; Spectrophotometry, Ultraviolet; Thermodynamics | 2001 |
Photolithographic synthesis of high-density oligonucleotide arrays.
Topics: 2-Aminopurine; Amides; Combinatorial Chemistry Techniques; Membrane Glycoproteins; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Phosphoric Acids; Photolysis; Purine Nucleosides | 2001 |
Matrix-induced fragmentation of P3'-N5' phosphoramidate-containing DNA: high-throughput MALDI-TOF analysis of genomic sequence polymorphisms.
Topics: Amides; Deoxycytosine Nucleotides; DNA; Genotype; Humans; Hydrolysis; Oligonucleotides; Phosphoric Acids; Picolinic Acids; Polymorphism, Single Nucleotide; Receptors, Adrenergic, beta-3; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymine Nucleotides | 2001 |
Commercially available 5'-DMT phosphoramidites as reagents for the synthesis of vinylphosphonate-linked oligonucleic acids.
Topics: Amides; Molecular Structure; Oligonucleotides; Organophosphonates; Organophosphorus Compounds; Phosphoric Acids; Vinyl Compounds | 2001 |
Synthesis and thermodynamic studies of oligonucleotides containing the two isomers of thymine glycol.
Topics: Amides; DNA Damage; Drug Stability; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; Stereoisomerism; Temperature; Thermodynamics; Thymine | 2001 |
Allosteric inhibitors of telomerase: oligonucleotide N3'-->P5' phosphoramidates.
Topics: Allosteric Regulation; Allosteric Site; Amides; Animals; Base Sequence; Cell Line; COS Cells; DNA Primers; DNA-Binding Proteins; DNA, Single-Stranded; Humans; Inhibitory Concentration 50; Kinetics; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Oligonucleotides; Oligonucleotides, Antisense; Phosphoric Acids; Recombinant Proteins; RNA; Telomerase; Templates, Genetic; Thermodynamics | 2002 |
Oligonucleotide N3'-->P5' phosphoramidates as efficient telomerase inhibitors.
Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Cell Division; Enzyme Inhibitors; Female; Humans; Oligonucleotides; Phosphoric Acids; Telomerase; Telomere; Tumor Cells, Cultured | 2002 |
Base-pairing systems related to TNA: alpha-threofuranosyl oligonucleotides containing phosphoramidate linkages.
Topics: Amides; Base Pairing; Chromatography, High Pressure Liquid; Circular Dichroism; DNA; Furans; Indicators and Reagents; Oligonucleotides; Phosphoric Acids; RNA; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet | 2002 |
3'-amino-2',4'-BNA: novel bridged nucleic acids having an N3'-->P5' phosphoramidate linkage.
Topics: Amides; Bridged-Ring Compounds; DNA; Molecular Structure; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligonucleotides; Phosphoric Acids; Phosphoric Diester Hydrolases; RNA; Snake Venoms | 2001 |
Promotion of triplex formation by N3'-->P5' phosphoramidate modification: thermodynamic and kinetic studies.
Topics: Amides; DNA; Kinetics; Oligonucleotides; Phosphoric Acids; Thermodynamics | 2001 |
Synergistic stabilization of triplex by combination of comb-type cationic copolymer and oligo-N3'-->P5' phosphoramidates.
Topics: Amides; Cations; Dextrans; DNA; Kinetics; Oligonucleotides; Phosphoric Acids; Polylysine; Pyrimidine Nucleotides | 2001 |
A novel telomerase template antagonist (GRN163) as a potential anticancer agent.
Topics: Amides; Biological Availability; Cell Survival; Dose-Response Relationship, Drug; Humans; Oligonucleotides; Phosphoric Acids; RNA; Telomerase | 2003 |
Tandem oligonucleotide synthesis using linker (First Base) phosphoramidites.
Topics: Amides; Electrophoresis, Capillary; Oligonucleotides; Phosphoric Acids | 2002 |
Synthesis and properties of 5'-amino-2',4'-BNA modified oligonucleotides with P3'-->N5' phosphoramidate linkages.
Topics: Amides; Base Sequence; Nucleic Acids; Oligonucleotides; Phosphoric Acids | 2002 |
Effects of oligonucleotide N3'-->P5' thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells.
Topics: Amides; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Humans; Multiple Myeloma; Oligonucleotides; Phosphoric Acids; RNA; Telomerase; Telomere | 2003 |
FTIR and UV spectroscopy studies of triplex formation between alpha-oligonucleotides with non-ionic phoshoramidate linkages and DNA targets.
Topics: Amides; Animals; Base Sequence; Chromatography, High Pressure Liquid; DNA; Hydrogen-Ion Concentration; Ions; Models, Chemical; Molecular Sequence Data; Oligonucleotides; Phosphoric Acids; Pyrimidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Temperature; Ultraviolet Rays | 2003 |
The merits of bipartite transition-state mimics for inhibition of uracil DNA glycosylase.
Topics: Amides; Binding, Competitive; DNA Glycosylases; DNA Repair; Enzyme Inhibitors; Escherichia coli Proteins; Hydrogen-Ion Concentration; Molecular Mimicry; Oligonucleotides; Phosphoric Acids; Structure-Activity Relationship; Uracil-DNA Glycosidase; Uridine | 2004 |
Binding and conformational analysis of phosphoramidate-restriction enzyme interactions.
Topics: Amides; Anisotropy; Binding Sites; Binding, Competitive; Collodion; Deoxyribonucleases, Type II Site-Specific; Dimerization; DNA; DNA Restriction Enzymes; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Ions; Kinetics; Magnetic Resonance Spectroscopy; Metals; Models, Chemical; Nucleic Acids; Oligonucleotides; Phosphoric Acids; Protein Binding; Protein Conformation; Proteins; Spectrometry, Fluorescence; Thermodynamics; Time Factors | 2004 |
Synthesis of monomers bearing at the 2'-position cyanomethoxycarbonyl group for phosphoramidite oligonucleotide synthesis.
Topics: Amides; Nuclear Magnetic Resonance, Biomolecular; Oligonucleotides; Phosphoric Acids; Spectrophotometry, Ultraviolet | 2004 |
Adjustment of the gamma dihedral angle of an oligonucleotide P3'-->N5' phosphoramidate enhances its binding affinity towards complementary strands.
Topics: Amides; Base Sequence; Binding Sites; Hydrolysis; Ligands; Models, Chemical; Nucleic Acid Conformation; Nucleic Acids; Oligonucleotides; Phosphoric Acids; Temperature; Thymine; Time Factors | 2005 |
Synergistic stabilization of nucleic acid assembly by oligo-N3'-->P5' phosphoramidate modification and additions of comb-type cationic copolymers.
Topics: Amides; Circular Dichroism; DNA; Electrophoresis; Hydrogen-Ion Concentration; Kinetics; Oligonucleotides; Phosphoric Acids | 2005 |
Highly stable DNA triplexes formed with cationic phosphoramidate pyrimidine alpha-oligonucleotides.
Topics: Amides; Base Sequence; Circular Dichroism; DNA; Hydrogen-Ion Concentration; Models, Chemical; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Pyrimidines; Temperature; Ultraviolet Rays | 2005 |
Structural arrangement of DNA constrained by a cross-linker.
Topics: Amides; Base Sequence; Circular Dichroism; Cross-Linking Reagents; Disulfides; DNA; Electrophoresis, Polyacrylamide Gel; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Stereoisomerism; Temperature | 2005 |
Synthesis and properties of aminopropyl nucleic acids.
Topics: Adenine; Amides; Amines; Base Pairing; Nucleic Acid Denaturation; Nucleosides; Oligonucleotides; Phosphoric Acids; Temperature; Thymine | 2005 |
Unique 31P spectral response to the formation of a specific restriction enzyme-DNA complex.
Topics: Amides; Crystallization; Deoxyribonucleases, Type II Site-Specific; DNA; Fluorescence Resonance Energy Transfer; Magnetic Resonance Spectroscopy; Oligonucleotides; Phosphoric Acids; Phosphorus Isotopes; Reference Standards; Sensitivity and Specificity; Structure-Activity Relationship | 2006 |
Base-pairing systems related to TNA containing phosphoramidate linkages: synthesis of building blocks and pairing properties.
Topics: Amides; Base Pairing; Cross-Linking Reagents; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Tetroses | 2004 |
Antiadhesive effects of GRN163L--an oligonucleotide N3'->P5' thio-phosphoramidate targeting telomerase.
Topics: Amides; Animals; Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Line, Tumor; Humans; Lung Neoplasms; Mice; Mice, Nude; Oligonucleotides; Oligopeptides; Phosphoric Acids; RNA; Telomerase; Telomere; Xenograft Model Antitumor Assays | 2007 |
Double-stranded DNA-templated oligonucleotide digestion triggered by triplex formation.
Topics: Amides; DNA; Hydrogen-Ion Concentration; Hydrolysis; Models, Molecular; Nucleic Acid Conformation; Nucleic Acids; Oligonucleotide Probes; Oligonucleotides; Phosphoric Acids; Sequence Analysis, DNA; Time Factors | 2007 |
Telomerase targeted oligonucleotide thio-phosphoramidates in T24-luc bladder cancer cells.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Humans; Oligonucleotides; Oligopeptides; Phosphoric Acids; RNA; Telomerase; Urinary Bladder Neoplasms | 2008 |
Synthesis of DNA-oligonucleotides damaged by arylamine-modified 2'-deoxyguanosine.
Topics: Amides; Amines; Aniline Compounds; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Oligonucleotides; Phosphoric Acids | 2007 |
Synthesis of a 4-selenothymidine phosphoramidite and incorporation into oligonucleotides.
Topics: Amides; Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Selenium; Spectrometry, Mass, Electrospray Ionization; Thymidine | 2008 |
Solid-phase synthesis of branched oligonucleotides.
Topics: Amides; Combinatorial Chemistry Techniques; DNA, Single-Stranded; Oligonucleotides; Phosphoric Acids; RNA Splicing; RNA, Bacterial | 2002 |
Methoxyoxalamido chemistry in the synthesis of tethered phosphoramidites and functionalized oligonucleotides.
Topics: Amides; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Oligonucleotides; Phosphoric Acids; Spectrometry, Mass, Electrospray Ionization | 2006 |
Nucleobase-caged phosphoramidites for oligonucleotide synthesis.
Topics: Amides; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Microscopy, Confocal; Oligonucleotides; Phosphoric Acids | 2007 |
Synthesis of altritol nucleoside phosphoramidites for oligonucleotide synthesis.
Topics: Amides; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nucleosides; Oligonucleotides; Phosphoric Acids; Sugar Alcohols | 2007 |
Solid-phase oligonucleotide labeling with DOTA.
Topics: Amides; Heterocyclic Compounds, 1-Ring; Magnetic Resonance Spectroscopy; Oligonucleotides; Phosphoric Acids; Spectrometry, Mass, Electrospray Ionization | 2007 |
A universal and recyclable solid support for oligonucleotide synthesis.
Topics: Amides; Chromatography, Thin Layer; Esterification; Magnetic Resonance Spectroscopy; Oligonucleotides; Phosphoric Acids | 2007 |
Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies.
Topics: Amides; Aminocaproic Acid; Arginine; Biological Transport; Endosomes; HeLa Cells; Heparin; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Liposomes; Morpholines; Oligonucleotides; Peptides; Phosphoric Acids; Stereoisomerism; Structure-Activity Relationship | 2008 |
Towards the synthesis of inosine building blocks for the preparation of oligonucleotides with hydrophobic alkyl chains between the nucleotide units.
Topics: Amides; Hydrochloric Acid; Inosine; Models, Chemical; Molecular Structure; Oligonucleotides; Organophosphorus Compounds; Phosphoric Acids; Stereoisomerism | 2009 |
Reverse-direction (5'-->3') synthesis of oligonucleotides containing a 3'-S-phosphorothiolate linkage and 3'-terminal 3'-thionucleosides.
Topics: Amides; Base Sequence; Chromatography, High Pressure Liquid; Oligonucleotides; Phosphoric Acids; Sulfhydryl Compounds; Thionucleosides | 2010 |
Cleavage of oligonucleotides containing a P3'→N5' phosphoramidate linkage mediated by single-stranded oligonucleotide templates.
Topics: Amides; Base Sequence; DNA; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Denaturation; Oligonucleotides; Phosphoric Acids; RNA; Templates, Genetic; Thermodynamics; Ultraviolet Rays | 2011 |
Advanced aqueous-phase phosphoramidation reactions for effectively synthesizing peptide-oligonucleotide conjugates trafficked into a human cell line.
Topics: Amides; Cell Line, Tumor; Cell Survival; Cell-Penetrating Peptides; Disulfides; Flow Cytometry; Humans; Imidazoles; Microscopy, Confocal; Microscopy, Fluorescence; Nucleic Acids; Oligonucleotides; Phosphoric Acids; Protein Transport; Solutions; tat Gene Products, Human Immunodeficiency Virus; Water | 2012 |
Azide-alkyne cycloaddition for universal post-synthetic modifications of nucleic acids and effective synthesis of bioactive nucleic acid conjugates.
Topics: Alkynes; Amides; Azides; Biological Transport; Catalysis; Cell Line; Cell Survival; Click Chemistry; Copper; Cycloaddition Reaction; Epithelial Cells; Humans; Nucleic Acids; Oligonucleotides; Peptides; Phosphoric Acids; Stereoisomerism | 2014 |
Oxidative substitution of boranephosphonate diesters as a route to post-synthetically modified DNA.
Topics: Amides; Azides; Boron Compounds; Chemistry Techniques, Synthetic; Dimerization; DNA; Esters; Ethylamines; Iodine; Magnetic Resonance Spectroscopy; Oligonucleotides; Organophosphonates; Oxidation-Reduction; Phosphoric Acids; Stereoisomerism | 2015 |
Phosphoramidate Ligation of Oligonucleotides in Nanoscale Structures.
Topics: Amides; Carbodiimides; Nanostructures; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; RNA, Small Interfering | 2016 |
Oligodeoxynucleotides containing 2'-amino-LNA nucleotides as constrained morpholino phosphoramidate and phosphorodiamidate monomers.
Topics: Amides; DNA; Molecular Dynamics Simulation; Morpholinos; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Oligonucleotides; Phosphoric Acids; Transition Temperature | 2017 |
Synthesis of Chimeric Oligonucleotides Having Modified Internucleotide Linkages via an Automated H-Phosphonate/Phosphoramidite Approach.
Topics: Amides; Automation; Esters; Oligonucleotides; Organophosphonates; Phosphoric Acids; Spectrometry, Mass, Electrospray Ionization | 2018 |
Synthesis of Trinucleotide Building Blocks in Solution and on Solid Phase.
Topics: Amides; Oligonucleotides; Phosphoric Acids; Proton Magnetic Resonance Spectroscopy; Siloxanes; Solutions; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Styrenes | 2018 |
Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties.
Topics: Amides; Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA; Melanoma, Experimental; Mice; MicroRNAs; Oligonucleotides; Oligonucleotides, Antisense; Phosphates; Phosphoric Acids; Ribonuclease H; RNA | 2019 |
Solid-Phase Synthesis of Phosphorothioate/Phosphonothioate and Phosphoramidate/Phosphonamidate Oligonucleotides.
Topics: Amides; Dimerization; Molecular Structure; Oligonucleotides; Phosphates; Phosphoric Acids; Phosphorothioate Oligonucleotides; Solid-Phase Synthesis Techniques | 2019 |
Sequencing of Phosphoramidate Oligonucleotides by Acid Hydrolysis and Mass Spectrometry.
Topics: Amides; Formates; Hydrolysis; Mass Spectrometry; Oligonucleotides; Phosphoric Acids | 2019 |
DNA polymerase activity on synthetic N3'→P5' phosphoramidate DNA templates.
Topics: Amides; Base Sequence; Circular Dichroism; DNA; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Polymerization; RNA; RNA-Directed DNA Polymerase; Templates, Genetic | 2019 |
In Vivo Expression of Genetic Information from Phosphoramidate-DNA.
Topics: Amides; DNA; Gene Expression Profiling; Hydrogen-Ion Concentration; Oligonucleotides; Phosphoric Acids; Polymerase Chain Reaction | 2020 |
Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase.
Topics: Amides; DNA; DNA-Directed DNA Polymerase; Magnetic Resonance Spectroscopy; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Polymerization; RNA | 2020 |
Nucleic Acid Conformation Influences Postsynthetic Suzuki-Miyaura Labeling of Oligonucleotides.
Topics: Amides; Base Sequence; DNA; Fluorescent Dyes; G-Quadruplexes; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Telomere | 2020 |
Immobilized Carbohydrates for Preparation of 3'-Glycoconjugated Oligonucleotides.
Topics: Amides; Carbohydrate Conformation; Carbohydrate Sequence; Carbohydrates; Glycoconjugates; Oligonucleotides; Phosphoric Acids; Spectrum Analysis | 2020 |
New Oligonucleotide 2'-O-Alkyl N3'→P5' (Thio)-Phosphoramidates as Potent Antisense Agents: Physicochemical Properties and Biological Activity.
Topics: Amides; Oligonucleotides; Oligonucleotides, Antisense; Phosphoric Acids | 2023 |
Fork- and Comb-like Lipophilic Structures: Different Chemical Approaches to the Synthesis of Oligonucleotides with Multiple Dodecyl Residues.
Topics: Guanidine; Guanidines; Oligonucleotides; Phosphates | 2023 |