phosphoramidic acid has been researched along with guanosine in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumpins, V; Stankevich, E | 1 |
| Orgel, LE; Zielinski, WS | 1 |
| Gait, MJ; Grasby, JA; Mersmann, K; Singh, M | 1 |
| Fu, DJ; McLaughlin, LW; Rajur, SB | 1 |
| Debart, F; Michel, T; Naval, M; Vasseur, JJ | 1 |
| Madela, K; McGuigan, C; Neyts, J; Perrone, P | 1 |
| Aljarah, M; Ames, B; Bryant, KD; Chamberlain, S; Ganguly, B; Gilles, A; Gorovits, E; Hall, A; Henson, G; Holl, S; Hunley, D; Hutchins, J; Jones, S; Kolykhalov, A; Liu, Y; Madela, K; McGuigan, C; Muhammad, J; Raja, N; Vernachio, J; Walters, R; Wang, J | 1 |
| Aljarah, M; Ames, B; Brancale, A; Chamberlain, S; Ganguly, B; Gilles, A; Gorovits, E; Hall, A; Henson, G; Hutchins, J; Kolykhalov, A; Madela, K; McGuigan, C; Muhammad, J; Patti, JM; Vernachio, J; Wang, J; Zonta, N | 1 |
| Mehellou, Y | 1 |
| Aljarah, M; Ames, B; Bleiman, B; Bryant, KD; Chamberlain, S; Ganguly, B; Gilles, A; Gorovits, E; Hall, A; Henson, G; Hunley, D; Hutchins, J; Kolykhalov, A; Liu, Y; Madela, K; McGuigan, C; Muhammad, J; Patti, JM; Raja, N; Vernachio, JH; Walters, CR; Wang, J; Williams, K | 1 |
10 other study(ies) available for phosphoramidic acid and guanosine
| Article | Year |
|---|---|
Solid phase synthesis of oligoribonucleotides.
Topics: Adenosine; Amides; Chromatography, High Pressure Liquid; Cytidine; Electrophoresis, Polyacrylamide Gel; Guanosine; Indicators and Reagents; Oligoribonucleotides; Phosphoric Acids | 1991 |
The template properties of tetranucleoside triphosphoramidates having cytosine-guanosine residues.
Topics: Amides; Cytosine; Guanosine; Phosphoric Acids; Polymers; Templates, Genetic | 1989 |
Purine functional groups in essential residues of the hairpin ribozyme required for catalytic cleavage of RNA.
Topics: Adenosine; Amides; Base Sequence; Guanosine; Indicators and Reagents; Kinetics; Magnesium; Molecular Sequence Data; Nucleic Acid Conformation; Phosphoric Acids; Purines; RNA; RNA, Catalytic; Structure-Activity Relationship | 1995 |
Importance of specific guanosine N7-nitrogens and purine amino groups for efficient cleavage by a hammerhead ribozyme.
Topics: Amides; Base Composition; Base Sequence; Binding Sites; Guanosine; Indicators and Reagents; Molecular Sequence Data; Nucleic Acid Conformation; Nucleosides; Phosphoric Acids; Purines; RNA, Catalytic | 1993 |
2-Amino-alpha-2'-deoxyadenosine increased duplex stability of methoxyethylphosphoramidate alpha-oligodeoxynucleotides with RNA target.
Topics: Amides; Base Sequence; Cytosine; Deoxyadenosines; DNA, Complementary; Guanosine; Hot Temperature; Nucleic Acid Denaturation; Nucleic Acid Heteroduplexes; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Phosphoric Acids; RNA | 2002 |
The phosphoramidate ProTide approach greatly enhances the activity of beta-2'-C-methylguanosine against hepatitis C virus.
Topics: Amides; Amino Acids; Antiviral Agents; Chemistry, Pharmaceutical; Drug Design; Esters; Guanosine; Hepacivirus; Hepatitis C; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Models, Chemical; Phosphoric Acids; Prodrugs | 2009 |
Phosphoramidate ProTides of 2'-C-methylguanosine as highly potent inhibitors of hepatitis C virus. Study of their in vitro and in vivo properties.
Topics: Adenosine Triphosphate; Amides; Animals; Antiviral Agents; Cell Line; Female; Guanosine; Hepacivirus; Hepatitis C; Humans; Liver; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Phosphoric Acids; Virus Replication | 2010 |
Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus.
Topics: Amides; Antiviral Agents; Cells, Cultured; Drug Design; Guanosine; Guanosine Monophosphate; Hepacivirus; Humans; Phosphoric Acids; Prodrugs | 2010 |
Phosphoramidate prodrugs deliver with potency against hepatitis C virus.
Topics: Amides; Anti-HIV Agents; DNA-Directed RNA Polymerases; Guanosine; Hepacivirus; Hepatitis C; Humans; Phosphoric Acids; Prodrugs; Pyrimidine Nucleosides | 2010 |
INX-08189, a phosphoramidate prodrug of 6-O-methyl-2'-C-methyl guanosine, is a potent inhibitor of hepatitis C virus replication with excellent pharmacokinetic and pharmacodynamic properties.
Topics: Amides; Animals; Antiviral Agents; Cell Line; Cell Line, Tumor; Guanosine; Hepacivirus; Humans; Macaca fascicularis; Male; Phosphoric Acids; Prodrugs; Rats; Rats, Sprague-Dawley; Virus Replication | 2011 |