phosphoramide mustard has been researched along with 4-hydroxycyclophosphamide in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Baturay, NZ; Fan, J; Jain, M; Kwon, CH | 1 |
| Bryant, MF; Erexson, GL; Kligerman, AD; Kwanyuen, P | 1 |
| Bryant, MF; Erexson, GL; Kligerman, AD | 1 |
| Alberts, DS; Horne, K; Peng, YM; Phillips, JG; Roe, DJ; Struck, RF | 1 |
| Borch, RF; Kwon, CH; LoCastro, L; Maddison, K | 1 |
| Alberts, DS; Struck, RF | 1 |
| Powers, JF; Sladek, NE | 1 |
| Hales, BF | 1 |
| Dirven, HA; van Bladeren, PJ; van Ommen, B; Venekamp, JC | 1 |
| Dirven, HA; van Bladeren, PJ; van Ommen, B | 1 |
| Chan, KK; Hong, PS; Trump, DL; Tutsch, K | 1 |
| Fuchs, J; Hengst, A; Hengstler, JG; Oesch, F; Pohl, J; Tanner, B | 1 |
| Beijnen, JH; de Jonge, ME; Huitema, AD; Rodenhuis, S; van Dam, SM | 1 |
| Abir, R; Ben-Haroush, A; Farhi, J; Fisch, B; Kessler-Icekson, G; Lande, Y; Ludeman, SM; Prag-Rosenberg, R; Tsur, A; Zahalka, MA | 1 |
| Voelcker, G | 1 |
3 trial(s) available for phosphoramide mustard and 4-hydroxycyclophosphamide
| Article | Year |
|---|---|
Plasma pharmacokinetics of cyclophosphamide and its cytotoxic metabolites after intravenous versus oral administration in a randomized, crossover trial.
Topics: Administration, Oral; Clinical Trials as Topic; Cyclophosphamide; Humans; Injections, Intravenous; Kinetics; Phosphoramide Mustards; Random Allocation | 1987 |
Clinical pharmacokinetics of cyclophosphamide and metabolites with and without SR-2508.
Topics: Cyclophosphamide; Etanidazole; Humans; Phosphoramide Mustards; Pyridines; Time Factors | 1994 |
Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin.
Topics: Adolescent; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Carboplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Models, Biological; Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Phosphoramide Mustards; Prodrugs; Thiotepa; Time Factors; Triethylenephosphoramide | 2005 |
12 other study(ies) available for phosphoramide mustard and 4-hydroxycyclophosphamide
| Article | Year |
|---|---|
Sulfonyl-containing aldophosphamide analogues as novel anticancer prodrugs targeted against cyclophosphamide-resistant tumor cell lines.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cricetinae; Cyclophosphamide; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Stability; Half-Life; Humans; Mice; Phosphoramide Mustards; Prodrugs; Structure-Activity Relationship; Sulfones; Transplantation, Heterologous | 2004 |
Comparison of sister-chromatid exchange frequencies in mouse T- and B-lymphocytes after exposure to 4-hydroxycyclophosphamide or phosphoramide mustard.
Topics: Animals; B-Lymphocytes; Cells, Cultured; Cyclophosphamide; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Phosphoramide Mustards; Phytohemagglutinins; Sister Chromatid Exchange; T-Lymphocytes | 1990 |
A comparison of sister-chromatid exchange in mouse peripheral blood lymphocytes exposed in vitro and in vivo to phosphoramide mustard and 4-hydroxycyclophosphamide.
Topics: Animals; Cell Cycle; Cells, Cultured; Cyclophosphamide; Dose-Response Relationship, Drug; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Phosphoramide Mustards; Sister Chromatid Exchange | 1989 |
Accelerated decomposition of 4-hydroxycyclophosphamide by human serum albumin.
Topics: Cell Survival; Cyclophosphamide; Dose-Response Relationship, Drug; Humans; Hydrolysis; Kinetics; Phosphoramide Mustards; Serum Albumin | 1987 |
Blood levels of alkylating metabolites of cyclophosphamide in the mouse after iv or oral administration.
Topics: Administration, Oral; Animals; Biological Availability; Chemical Phenomena; Chemistry; Cyclophosphamide; Humans; Injections, Intravenous; Male; Mice; Phosphoramide Mustards; Time Factors | 1984 |
Cytotoxic activity relative to 4-hydroxycyclophosphamide and phosphoramide mustard concentrations in the plasma of cyclophosphamide-treated rats.
Topics: Animals; Cell Survival; Cyclophosphamide; Female; Male; Mammary Neoplasms, Experimental; Mice; Phosphoramide Mustards; Rats; Rats, Inbred Strains; Sarcoma, Experimental; Time Factors | 1983 |
Comparison of the mutagenicity and teratogenicity of cyclophosphamide and its active metabolites, 4-hydroxycyclophosphamide, phosphoramide mustard, and acrolein.
Topics: Acrolein; Aldehydes; Animals; Cyclophosphamide; Drug Evaluation, Preclinical; Embryo, Mammalian; Female; Mutagenicity Tests; Mutagens; Mutation; Phosphoramide Mustards; Pregnancy; Rats; Rats, Inbred Strains; Salmonella typhimurium; Structure-Activity Relationship; Teratogens | 1982 |
The interaction of glutathione with 4-hydroxycyclophosphamide and phosphoramide mustard, studied by 31P nuclear magnetic resonance spectroscopy.
Topics: Cyclophosphamide; Glutathione; Magnetic Resonance Spectroscopy; Phosphoramide Mustards; Phosphorus Radioisotopes; Spectrometry, Mass, Fast Atom Bombardment | 1994 |
Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione.
Topics: Biotransformation; Cyclophosphamide; Glutathione; Glutathione Transferase; Humans; Isoenzymes; Phosphoramide Mustards | 1994 |
Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1.
Topics: Animals; Biotransformation; Cell Line; Cricetinae; Cricetulus; Cyclophosphamide; Cytochrome P-450 Enzyme System; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Phosphoramide Mustards; Transfection | 1997 |
Short-term exposure of human ovarian follicles to cyclophosphamide metabolites seems to promote follicular activation in vitro.
Topics: Adolescent; Anti-Mullerian Hormone; Child; Cryopreservation; Culture Media; Cyclophosphamide; Embryo Culture Techniques; Estradiol; Female; Freezing; Humans; Immunosuppressive Agents; Ki-67 Antigen; Ovarian Follicle; Ovary; Phosphoramide Mustards; Time Factors | 2017 |
Causes and possibilities to circumvent cyclophosphamide toxicity.
Topics: Animals; Antineoplastic Agents, Alkylating; Cell Proliferation; Cyclophosphamide; Female; Leukemia P388; Male; Mice; Phosphoramide Mustards; Toxicity Tests | 2020 |