Page last updated: 2024-08-23

phosphopantothenic acid and pantothenic acid

phosphopantothenic acid has been researched along with pantothenic acid in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's3 (14.29)18.2507
2000's3 (14.29)29.6817
2010's7 (33.33)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Germinario, RJ; Waller, JR1
Baldwin, JE; Bird, JW; Field, RA; O'Callaghan, NM; Schofield, CJ; Willis, AC1
Campbell, EH; Fixter, LM; McAllister, RA1
Efimov, AS; Moiseenok, AG; Obrosova, IG; Ostrovskiĭ, IuM; Tsyruk, VL1
Komaki, R; Shimizu, S; Tani, Y; Yamada, H1
Dorofeev, BF; Kopelevich, VM; Korablev, MV1
Jackowski, S; Rock, CO1
Moiseenok, AG; Rakowska, M; Slyshenkov, VS; Wojtczak, L1
Keating, TA; Patel, HM; Quadri, LE; Walsh, CT1
Grünewald, J; Marahiel, MA; Sieber, SA1
Dorrestein, PC; Ju, J; Kelleher, NL; Li, W; Liu, W; Shen, B; Van Lanen, SG; Zhang, J1
Chetnani, B; Das, S; Kumar, P; Surolia, A; Vijayan, M1
Aldrich, CC; Blanchard, JS; Sikora, AL; Wilson, DJ1
Abhinav, KV; Chetnani, B; Chhibber, M; Kumar, P; Surolia, A; Vijayan, M1
Atomi, H; Hiratake, J; Imanaka, T; Ishibashi, T; Kishimoto, A; Kita, A; Miki, K; Morikita, T; Tomita, H; Watanabe, B; Yokooji, Y1
Chohnan, S; Hanada, S; Katoh, H; Tamaki, H; Tokutake, Y1
Bandodkar, B; Bergfors, T; Björkelid, C; Jones, TA; Malolanarasimhan, K; Mukherjee, K; Raichurkar, AK1
Frank, M; Jackowski, S; Pate, C; Rock, CO; Zano, SP1
Beconi, MG; Di Marco, A; Elbaum, D; Harper, S; Lyons, KA; Monteagudo, E; Quinton, MS; Vaino, A1
Auciello, G; Beconi, M; Bracacel, E; Ciammaichella, A; Cicero, D; Di Marco, A; Elbaum, D; Fezzardi, P; Gonzalez Paz, O; Harper, S; Malancona, S; Monteagudo, E; Rossetti, I; Vecchi, A1
Ben Mamoun, C; Ceccatelli Berti, C; Choi, JY; Figuccia, S; Gihaz, S; Goffrini, P; Pal, AC1

Other Studies

21 other study(ies) available for phosphopantothenic acid and pantothenic acid

ArticleYear
Phosphopantothenic acid--the major product of pantothenic acid accumulation and a significant growth stimulatn in Lactobacillus plantarum.
    Canadian journal of microbiology, 1976, Volume: 22, Issue:3

    Topics: Alkaline Phosphatase; Cell-Free System; Hydrolysis; Lactobacillus; Pantetheine; Pantothenic Acid; Saccharomyces

1976
Isolation and partial characterisation of ACV synthetase from Cephalosporium acremonium and Streptomyces clavuligerus. Evidence for the presence of phosphopantothenate in ACV synthetase.
    The Journal of antibiotics, 1991, Volume: 44, Issue:2

    Topics: Acremonium; Amino Acid Sequence; Chemical Fractionation; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Molecular Sequence Data; Pantothenic Acid; Peptide Synthases; Streptomyces

1991
The effect of tumour growth on liver pantothenate, CoA, and fatty acid synthetase activity in the mouse.
    British journal of cancer, 1988, Volume: 57, Issue:1

    Topics: Acetyl Coenzyme A; Animals; Coenzyme A; Fatty Acid Synthases; Fibrosarcoma; Liver; Lymphoma; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Sarcoma 180

1988
[Effect of phosphopantothenate on the biosynthesis of cholesterol and its esters from various precursors in the liver of db/db mice].
    Biokhimiia (Moscow, Russia), 1988, Volume: 53, Issue:11

    Topics: Acetates; Animals; Cholesterol; Cholesterol Esters; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hyperinsulinism; Liver; Mevalonic Acid; Mice; Mice, Inbred C57BL; Obesity; Pantothenic Acid; Pyruvates

1988
A high yield method for the preparative synthesis of coenzyme A by combination of chemical and enzymic reactions.
    FEBS letters, 1983, Jan-24, Volume: 151, Issue:2

    Topics: Brevibacterium; Coenzyme A; Feedback; Kinetics; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Substrate Specificity

1983
[Alteration of the acute toxicity and various pharmacologic effects of streptomycin sulfate by calcium 4'-phosphopantothenate].
    Antibiotiki, 1983, Volume: 28, Issue:10

    Topics: Acute Disease; Animals; Body Temperature; Female; Male; Mice; Muscles; Orientation; Oxygen Consumption; Pantothenic Acid; Reflex; Streptomycin

1983
Regulation of coenzyme A biosynthesis.
    Journal of bacteriology, 1981, Volume: 148, Issue:3

    Topics: Acyl Carrier Protein; beta-Alanine; Coenzyme A; Escherichia coli; Organophosphorus Compounds; Pantetheine; Pantothenic Acid

1981
Pantothenic acid and its derivatives protect Ehrlich ascites tumor cells against lipid peroxidation.
    Free radical biology & medicine, 1995, Volume: 19, Issue:6

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Coenzyme A; Fatty Acids; Female; Ferrous Compounds; Hydrogen Peroxide; Lipid Peroxidation; Mice; Palmitic Acid; Palmitic Acids; Pantetheine; Pantothenic Acid; Thiobarbituric Acid Reactive Substances

1995
Assembly of the Pseudomonas aeruginosa nonribosomal peptide siderophore pyochelin: In vitro reconstitution of aryl-4, 2-bisthiazoline synthetase activity from PchD, PchE, and PchF.
    Biochemistry, 1999, Nov-09, Volume: 38, Issue:45

    Topics: Adenosine Triphosphate; Bacterial Proteins; Catalysis; Chromatography, High Pressure Liquid; Cysteine; Diphosphates; Iron Chelating Agents; Pantothenic Acid; Peptide Synthases; Phenols; Protein Processing, Post-Translational; Pseudomonas aeruginosa; Salicylates; Siderophores; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles

1999
Chemo- and regioselective peptide cyclization triggered by the N-terminal fatty acid chain length: the recombinant cyclase of the calcium-dependent antibiotic from Streptomyces coelicolor.
    Biochemistry, 2004, Mar-16, Volume: 43, Issue:10

    Topics: Anti-Bacterial Agents; Calcium; Catalysis; Coenzyme A; Fatty Acids; Ionophores; Lactones; Pantothenic Acid; Peptide Fragments; Peptide Synthases; Peptides; Peptides, Cyclic; Protein Structure, Tertiary; Recombinant Fusion Proteins; Stereoisomerism; Streptomyces; Thioredoxins

2004
A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Feb-05, Volume: 105, Issue:5

    Topics: Acyl Carrier Protein; Amino Acid Sequence; Aminoglycosides; Antibiotics, Antineoplastic; Binding Sites; Computational Biology; Enediynes; Molecular Sequence Data; Pantothenic Acid; Polyenes; Polyketide Synthases; Protein Structure, Tertiary; Zinostatin

2008
Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action.
    Acta crystallographica. Section D, Biological crystallography, 2009, Volume: 65, Issue:Pt 4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Coenzyme A; Crystallization; Crystallography, X-Ray; Escherichia coli Proteins; Factor VIIa; Ligands; Models, Molecular; Mycobacterium tuberculosis; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Conformation; Recombinant Proteins; Species Specificity

2009
Kinetic and inhibition studies of dihydroxybenzoate-AMP ligase from Escherichia coli.
    Biochemistry, 2010, May-04, Volume: 49, Issue:17

    Topics: Binding Sites; Catalysis; Catalytic Domain; Dimerization; Enterobactin; Escherichia coli; Escherichia coli Proteins; Kinetics; Ligases; Models, Molecular; Multienzyme Complexes; Pantothenic Acid; Peptide Synthases; Substrate Specificity

2010
Location and conformation of pantothenate and its derivatives in Mycobacterium tuberculosis pantothenate kinase: insights into enzyme action.
    Acta crystallographica. Section D, Biological crystallography, 2011, Volume: 67, Issue:Pt 9

    Topics: Crystallography, X-Ray; Mycobacterium tuberculosis; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor)

2011
A detailed biochemical characterization of phosphopantothenate synthetase, a novel enzyme involved in coenzyme A biosynthesis in the Archaea.
    Extremophiles : life under extreme conditions, 2012, Volume: 16, Issue:6

    Topics: Adenosine Triphosphate; Alanine; Archaeal Proteins; Coenzyme A; Kinetics; Pantothenic Acid; Peptide Synthases; Phosphates; Phosphotransferases (Alcohol Group Acceptor); Thermococcus

2012
Identification of pantoate kinase and phosphopantothenate synthetase from Methanospirillum hungatei.
    Journal of bioscience and bioengineering, 2013, Volume: 115, Issue:4

    Topics: Coenzyme A; Escherichia coli; Ligases; Methanospirillum; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Uridine Triphosphate

2013
Structural and biochemical characterization of compounds inhibiting Mycobacterium tuberculosis pantothenate kinase.
    The Journal of biological chemistry, 2013, Jun-21, Volume: 288, Issue:25

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Biocatalysis; Crystallography, X-Ray; Enzyme Inhibitors; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mycobacterium tuberculosis; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity

2013
Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.
    Molecular genetics and metabolism, 2015, Volume: 116, Issue:4

    Topics: Administration, Oral; Amides; Animals; Coenzyme A; Disease Models, Animal; Embryo, Mammalian; Female; Fibroblasts; Gene Expression; Humans; Liver; Male; Mice; Mice, Knockout; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phosphoric Acids; Phosphotransferases (Alcohol Group Acceptor); Primary Cell Culture

2015
Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Animals; Blood-Brain Barrier; Cell Line, Tumor; Coenzyme A; Disease Models, Animal; Humans; Macaca fascicularis; Male; Mice, Inbred C57BL; Neurons; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Prodrugs; Rats, Sprague-Dawley; RNA Interference; Species Specificity

2018
Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration.
    Journal of medicinal chemistry, 2020, 12-24, Volume: 63, Issue:24

    Topics: Animals; Blood-Brain Barrier; Brain; Coenzyme A; Cyclization; Disease Models, Animal; Half-Life; Hepatocytes; Humans; Lipid Droplets; Mice; Mice, Inbred C57BL; Mice, Knockout; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Prodrugs; Structure-Activity Relationship

2020
Evidence for a Conserved Function of Eukaryotic Pantothenate Kinases in the Regulation of Mitochondrial Homeostasis and Oxidative Stress.
    International journal of molecular sciences, 2022, Dec-27, Volume: 24, Issue:1

    Topics: Homeostasis; Humans; Iron; Mitochondria; Oxidative Stress; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Saccharomyces cerevisiae

2022