phosphonoacetic acid has been researched along with thymidine in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (90.48) | 18.7374 |
| 1990's | 4 (9.52) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manor, D; Margalith, M | 1 |
| Kwong, LK; Tsuboi, KK | 1 |
| Ayisi, NK; Gupta, SV; Qualtiere, LF | 1 |
| Goldberg, RM; Krook, JE; Kugler, JW; Laurie, JA; Moertel, CG; O'Connell, MJ; Pfeifle, DM; Rubin, J; Wieand, HS; Windschitl, HE | 1 |
| De Clercq, E | 1 |
| Hirsch, MS; Schooley, RT; Vogt, M | 1 |
| Pomerantz, RJ; Schooley, RT | 1 |
| Bryson, YJ | 1 |
| Kaplan, JC; Sandström, EG | 1 |
| Broder, S; Yarchoan, R | 1 |
| De Clercq, E; Griengl, H; Hayden, W; Penn, G; Rosenwirth, B | 1 |
| Collins, P; Evans, R; Hawkins, DA; Lawrence, A; Oliver, N; Shanson, DC; Youle, MM | 1 |
| Buroker, TR; Cullinan, SA; Everson, LK; Fleming, TR; Klaassen, DJ; Krook, JE; Laurie, JA; Mailliard, JA; Marschke, RF; Moertel, CG | 1 |
| Sandström, E | 1 |
| Weber, J | 1 |
| Attanasio, R; Johnson, JC | 1 |
| Coen, DM; Fleming, HE; Leslie, LK; Retondo, MJ | 1 |
| Ayisi, NK; Babiuk, LA; Gupta, SV | 1 |
| Abele, G; Harmenberg, J; Wahren, B | 1 |
| Hoth, DF; King, SA; Leyland-Jones, B; O'Dwyer, PJ | 1 |
| Leyland-Jones, B; O'Dwyer, PJ | 1 |
| Bhalla, K; Grant, S | 1 |
| Akazawa, S; Ayusawa, D; Kumai, R; Seno, T; Shimizu, K; Yoshida, S | 1 |
| Bedikian, A; Bodey, GP; Chiuten, DF; Freireich, EJ; Valdivieso, M | 1 |
| Bedikian, A; Benvenuto, JA; Bodey, GP; Chiuten, DF; Freireich, EJ; Loo, TL; Miller, A; Valdivieso, M | 1 |
| Hoogenraad, J; Stark, GR; Yoshida, T | 1 |
| Presber, W; Schroeder, C | 1 |
| Janz, C; Wigand, R | 1 |
| Burkhardt, U; Wigand, R | 1 |
| Friedman-Kien, AE; Klein, RJ | 1 |
| Darby, G; Field, H; McMillan, A | 1 |
| Gentry, GA; Veerisetty, V | 1 |
| Baybutt, HN; Murray, BA; Pearson, CK | 1 |
| Kelley, E; Spector, SA; Tyndall, M | 1 |
| Bastow, KF; Cheng, YC; Derse, DD | 1 |
| Shapiro, WR; Young, DF | 1 |
| Hahn, RG; Kvols, LK; Moertel, CG; O'Connell, MJ; Rubin, J; Schutt, AJ | 1 |
| Casper, ES; Kemeny, N; Martin, DS; Michaelson, RA; Young, CW | 1 |
| Henderson, JF; Hunting, D | 1 |
| Grindey, GB; Kinahan, JJ; Kowal, EP | 1 |
| Li, YY; Minagawa, H; Mori, R; Tanaka, S | 1 |
| Docherty, JJ; Wilber, BA | 1 |
9 review(s) available for phosphonoacetic acid and thymidine
| Article | Year |
|---|---|
Chemotherapeutic approaches to the treatment of the acquired immune deficiency syndrome (AIDS).
Topics: Acquired Immunodeficiency Syndrome; Adsorption; Antibodies, Viral; Antigens, Viral; Aurintricarboxylic Acid; Deltaretrovirus; Deoxycytidine; Foscarnet; Genes, Viral; Glycoproteins; Humans; Interferons; Male; Phosphonoacetic Acid; Retroviridae Infections; Reverse Transcriptase Inhibitors; Ribavirin; RNA, Viral; Suramin; Thymidine; Transcription, Genetic; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine | 1986 |
Therapy of human immunodeficiency virus infections.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Foscarnet; Humans; Immunotherapy; Interferons; Oligodeoxyribonucleotides; Phosphonoacetic Acid; Ribavirin; Suramin; Thymidine; Zidovudine | 1987 |
Promising new antiviral drugs.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Herpes Simplex; Herpes Zoster; Humans; Interferons; Phosphonoacetic Acid; Ribavirin; Thymidine; Zidovudine | 1988 |
Antiviral therapy in AIDS. Clinical pharmacological properties and therapeutic experience to date.
Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Forecasting; Foscarnet; Immunotherapy; Phosphonoacetic Acid; Rifabutin; Rifamycins; Suramin; Thymidine; Tungsten; Tungsten Compounds; Zidovudine | 1987 |
Progress in the development of antiviral therapy for HTLV-III-associated diseases.
Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; HIV; Humans; Phosphonoacetic Acid; Ribavirin; Rifabutin; Rifamycins; Suramin; Thymidine; Tungsten; Tungsten Compounds; Zidovudine | 1987 |
Antiviral drugs for AIDS. Current status and future prospects.
Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; Humans; Interferon Type I; Phosphonoacetic Acid; Ribavirin; Suramin; Thymidine; Tungsten; Tungsten Compounds; Zidovudine | 1986 |
Role of thymidine in biochemical modulation: a review.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Deoxycytidine Kinase; DNA Replication; DNA, Neoplasm; Drug Evaluation; Drug Synergism; Fluorouracil; Folic Acid Antagonists; Humans; Interphase; Kinetics; Leukemia; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Nucleotides; Phosphonoacetic Acid; RNA, Neoplasm; Species Specificity; Thymidine | 1987 |
Biochemical modulation: application of laboratory models to the clinic.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Fluorouracil; Humans; Methotrexate; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Thymidine | 1986 |
Neurological complications of antineoplastic therapy.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Aspartic Acid; Cisplatin; Cytarabine; Fluorouracil; Humans; Methotrexate; Nervous System Diseases; Phosphonoacetic Acid; Thymidine; Vinblastine; Vincristine | 1984 |
3 trial(s) available for phosphonoacetic acid and thymidine
| Article | Year |
|---|---|
A clinical trial of biochemical modulation of 5-fluorouracil with N-phosphonoacetyl-L-aspartate and thymidine in advanced gastric and anaplastic colorectal cancer.
Topics: Adult; Aged; Aspartic Acid; Clinical Trials as Topic; Colorectal Neoplasms; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Middle Aged; Phosphonoacetic Acid; Stomach Neoplasms; Thymidine | 1990 |
[Chemotherapy and immunoprophylaxis of HIV infection].
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Foscarnet; HIV; Humans; Phosphonoacetic Acid; Reverse Transcriptase Inhibitors; Ribavirin; Suramin; Thymidine; Viral Vaccines; Virus Replication; Zidovudine | 1986 |
A controlled evaluation of recent approaches to biochemical modulation or enhancement of 5-fluorouracil therapy in colorectal carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Levamisole; Male; Middle Aged; Neoplasm Metastasis; Phosphonoacetic Acid; Random Allocation; Rectal Neoplasms; Semustine; Streptozocin; Thymidine; Vincristine | 1985 |
30 other study(ies) available for phosphonoacetic acid and thymidine
| Article | Year |
|---|---|
Phosphonoacetic acid: inhibition of transformation of human cord blood lymphocytes by Epstein-Barr virus.
Topics: Animals; Callitrichinae; Cell Line; Cell Transformation, Viral; Fetal Blood; Herpesvirus 4, Human; Humans; Infant, Newborn; Kinetics; Leukocytes; Lymphocytes; Organophosphorus Compounds; Phosphonoacetic Acid; Thymidine | 1979 |
Antiproliferative agents and differential survival between normal and cancer cells.
Topics: Adenocarcinoma; Aspartic Acid; Cell Cycle; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Thymidine | 1978 |
Modified tetrazolium-based colorimetric method for determining the activities of anti-HIV compounds.
Topics: Antiviral Agents; Cell Line; Colorimetry; Didanosine; Foscarnet; HIV-1; Humans; Phosphonoacetic Acid; Tetrazolium Salts; Thymidine; Zalcitabine; Zidovudine | 1991 |
Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Chemical Phenomena; Chemistry; Deoxyuridine; Foscarnet; Herpes Simplex; Mice; Organophosphorus Compounds; Pharmaceutical Preparations; Phosphonoacetic Acid; Prodrugs; Rabbits; Simplexvirus; Thymidine; Vero Cells | 1988 |
Acyclovir-resistant herpes in AIDS treated with foscarnet.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Drug Resistance, Microbial; Female; Foscarnet; Herpes Genitalis; Humans; Organophosphorus Compounds; Phosphonoacetic Acid; Simplexvirus; Thymidine; Zidovudine | 1988 |
AIDS: the virus, antivirals and vaccines.
Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; Genes, Viral; HIV; Humans; Phosphonoacetic Acid; Suramin; Thymidine; Tungsten; Tungsten Compounds; Viral Vaccines; Virus Replication; Zidovudine | 1987 |
Synergistic inhibition of anatid herpesvirus replication by acyclovir and phosphonocompounds.
Topics: Acyclovir; Animals; Deoxycytidine; Drug Interactions; Drug Resistance, Microbial; Foscarnet; Herpesviridae; Mutation; Organophosphorus Compounds; Phosphonoacetic Acid; Thymidine; Virus Replication | 1987 |
Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus.
Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Bromodeoxyuridine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Idoxuridine; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Vidarabine | 1985 |
Combination chemotherapy: interaction of 5-methoxymethyldeoxyuridine with trifluorothymidine, phosphonoformate and acycloguanosine against herpes simplex viruses.
Topics: Acyclovir; Animals; Antiviral Agents; Deoxyuridine; DNA, Viral; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Encephalitis; Foscarnet; Herpes Simplex; Male; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Rabbits; Simplexvirus; Thymidine; Trifluridine; Vidarabine; Virus Replication | 1985 |
Nucleoside pools of acyclovir-treated herpes simplex type 1 infected cells.
Topics: Acyclovir; Animals; Cells, Cultured; Chlorocebus aethiops; Foscarnet; Herpes Simplex; Humans; Kinetics; Nucleosides; Phosphonoacetic Acid; Thymidine | 1985 |
Effect of deoxycytidine on the in vitro response of human leukemia cells to inhibitors of de novo pyrimidine biosynthesis.
Topics: 3-Deazauridine; Amides; Aspartic Acid; Cell Division; Cell Line; Deoxycytidine; Deoxycytidine Kinase; Drug Interactions; Humans; Leukemia, Experimental; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Thymidine | 1987 |
[Biochemical modulation of 5-FU by thymidine and N-phosphoacetyl-L-aspartate: the relation between 5-FU incorporation into RNA and its cytocidal effect].
Topics: Animals; Aspartic Acid; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm; Drug Synergism; Female; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; RNA, Neoplasm; Thymidine; Tumor Stem Cell Assay | 1986 |
Phase I-II clinical trial of thymidine, 5-FU, and PALA given in combination.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Middle Aged; Phosphonoacetic Acid; Rectal Neoplasms; Thymidine | 1985 |
Sequential administration of thymidine, 5-fluorouracil, and PALA. A phase I-II study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Carcinoma, Bronchogenic; Chromatography, High Pressure Liquid; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Fluorouracil; Half-Life; Humans; Infusions, Parenteral; Middle Aged; Organophosphorus Compounds; Phosphonoacetic Acid; Stomach Neoplasms; Thymidine | 1985 |
Inhibition by N-(phosphonacetyl)-L-aspartate of aspartate transcarbamylase activity and drug-induced cell proliferation in mice.
Topics: Administration, Oral; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbon Radioisotopes; Cell Division; DNA; Female; Injections, Subcutaneous; Isoproterenol; Jejunum; Mice; Organophosphonates; Phosphonoacetic Acid; Spleen; Submandibular Gland; Thymidine; Time Factors; Tritium | 1974 |
[Current problems in medical virology. VI. Virostatics--what we need and what we have].
Topics: Acyclovir; Amantadine; Amides; Antiviral Agents; Guanidine; Guanidines; Guanine; Interferons; Methisazone; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Thymidine; Vidarabine; Virus Diseases | 1981 |
Combined interaction of antiherpes substances and interferon beta on the multiplication of herpes simplex virus.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Cell Line; Chlorocebus aethiops; Cytopathogenic Effect, Viral; Deoxyuridine; Drug Interactions; Foscarnet; Interferon Type I; Phosphonoacetic Acid; Simplexvirus; Tegafur; Thymidine; Vidarabine Phosphate | 1982 |
Combined chemotherapy of cutaneous herpes simplex infection of the guinea pig.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Deoxyuridine; Drug Therapy, Combination; Female; Foscarnet; Guinea Pigs; Herpes Simplex; Idoxuridine; Male; Phosphonoacetic Acid; Skin Diseases, Infectious; Thymidine; Trifluridine; Vidarabine Phosphate | 1983 |
Effect of eight antiviral drugs on the reactivation of herpes simplex virus in explant cultures of latently infected mouse trigeminal ganglia.
Topics: Acyclovir; Animals; Antibodies, Viral; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Bromodeoxyuridine; Culture Media; Culture Techniques; Cytarabine; Foscarnet; Mice; Mice, Hairless; Neutralization Tests; Phosphonoacetic Acid; Simplexvirus; Thymidine; Trigeminal Nerve; Vidarabine Phosphate; Virus Activation | 1984 |
The sensitivity of acyclovir-resistant mutants of herpes simplex virus to other antiviral drugs.
Topics: Acyclovir; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Drug Resistance, Microbial; Foscarnet; Guanine; Microbial Sensitivity Tests; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Trifluridine; Vidarabine | 1981 |
5-Methoxymethyldeoxyuridine-resistant mutants of herpes simplex virus type 1.
Topics: Acyclovir; Animals; Arabinonucleosides; Bromodeoxyuridine; Cell Line; Deoxyuridine; Drug Resistance, Microbial; Enzyme Induction; Guanine; Mice; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Thymidine Kinase | 1981 |
Aspects of thymidine metabolism and function in cultured mammalian cells infected with herpes simplex virus type 1.
Topics: Animals; Cell Line; Cricetinae; DNA; DNA-Directed DNA Polymerase; DNA, Viral; Kidney; Kinetics; Phosphonoacetic Acid; Phosphorylation; Simplexvirus; Thymidine; Thymine Nucleotides | 1982 |
Inhibition of human cytomegalovirus by trifluorothymidine.
Topics: Acyclovir; Cytomegalovirus; Foscarnet; Humans; Interferon Type I; Lung; Phosphonoacetic Acid; Thymidine; Trifluridine; Virus Replication | 1983 |
Susceptibility of phosphonoformic acid-resistant herpes simplex virus variants to arabinosylnucleosides and aphidicolin.
Topics: Antiviral Agents; Aphidicolin; Arabinonucleosides; Coformycin; Diterpenes; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Pentostatin; Phosphonoacetic Acid; Simplexvirus; Thymidine; Thymidine Kinase; Vidarabine | 1983 |
Clinical trial of sequential N-phosphonacetyl-L-aspartate, thymidine, and 5-fluorouracil in advanced colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Ataxia; Colonic Neoplasms; Confusion; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Middle Aged; Phosphonoacetic Acid; Rectal Neoplasms; Thymidine | 1984 |
Phase I evaluation of a biochemically designed combination: PALA, thymidine, and 5-FU.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Drug Evaluation; Fluorouracil; Humans; Neoplasms; Nervous System; Phosphonoacetic Acid; Thymidine | 1984 |
Relationship between ribo- and deoxyribonucleotide concentrations and biological parameters in cultured Chinese hamster ovary cells.
Topics: Amides; Animals; Aspartic Acid; Cell Cycle; Cells, Cultured; Cricetinae; Cricetulus; Deoxyribonucleotides; Female; Mycophenolic Acid; Ovary; Phosphonoacetic Acid; Pyrazoles; Ribonucleosides; Ribonucleotides; Ribose; Thymidine | 1982 |
Biochemical and antitumor effects of the combination of thymidine and 1-beta-D-arabinofuranosylcytosine against leukemia L1210.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Aspartic Acid; Cells, Cultured; Cytarabine; Cytidine; Drug Therapy, Combination; Leukemia L1210; Mice; Phosphonoacetic Acid; Thymidine | 1981 |
Suppression of infectious virus spread to the liver by foscarnet following lethal infection of acyclovir-resistant herpes simplex virus type 2 in mice.
Topics: Acyclovir; Animals; Arabinonucleosides; Brain; Chlorocebus aethiops; Drug Resistance, Microbial; Foscarnet; Hepatitis, Viral, Animal; Herpes Genitalis; Herpesvirus 2, Human; Humans; Injections, Intraperitoneal; Lethal Dose 50; Mice; Mice, Inbred C3H; Phosphonoacetic Acid; Thymidine; Vero Cells; Vidarabine | 1995 |
Analysis of the thymidine kinase of a herpes simplex virus type 1 isolate that exhibits resistance to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Topics: Acyclovir; Amino Acid Sequence; Antiviral Agents; Base Sequence; Binding Sites; Bromodeoxyuridine; Deoxyuridine; Drug Resistance, Microbial; Herpesvirus 1, Human; Humans; Kinetics; Molecular Sequence Data; Phosphonoacetic Acid; Phosphorylation; Point Mutation; Sequence Analysis, DNA; Thymidine; Thymidine Kinase; Vidarabine | 1994 |