phosphonoacetic acid has been researched along with pyrazofurin in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hart, IR; Kalebic, T; McMillan, TJ; Stark, GR | 1 |
| Chisena, CA; Cowan, KH; Cysyk, RL; Karle, JM | 1 |
| Bhalla, K; Grant, S | 1 |
| Giulotto, E; Knights, C; Stark, GR | 1 |
| Presber, W; Schroeder, C | 1 |
| Anderson, LW; Cysyk, RL; Dietrick, DD; Karle, JM | 1 |
| Henderson, JF; Hunting, D | 1 |
| Handschumacher, RE; Levy, EJ; Moyer, JD; Smith, PA | 1 |
| Handschumacher, RE; Moyer, JD; Oliver, JT | 1 |
| Ardalan, B; Cooney, DA; Cysyk, RL; Han, N; Hankerson, JG; Harley, C; Jayaram, HN; Johnson, RK; Kensler, TW; Mutter, G; Reck, LJ | 1 |
| Clarkin, KC; Di Leonardo, A; Linke, SP; Tsou, A; Wahl, GM | 1 |
| Cowan, KH; Gudas, JM; Li, T; Nguyen, H; Robey, R; Sadzewicz, L; Wosikowski, K | 1 |
| Lin, YH; Ravatn, R; Stollar, V; Yadav, P | 1 |
| Peters, GJ | 1 |
14 other study(ies) available for phosphonoacetic acid and pyrazofurin
| Article | Year |
|---|---|
High frequency of double drug resistance in the B16 melanoma cell line.
Topics: Amides; Animals; Antineoplastic Agents; Aspartic Acid; Cell Line; Colony-Forming Units Assay; Drug Resistance; Drug Synergism; Gene Amplification; Melanoma; Methotrexate; Mice; Ouabain; Phosphonoacetic Acid; Pyrazoles; Ribonucleosides; Ribose | 1990 |
Uracil nucleotide synthesis in a human breast cancer cell line (MCF-7) and in two drug-resistant sublines that contain increased levels of enzymes of the de novo pyrimidine pathway.
Topics: Amides; Aspartate Carbamoyltransferase; Aspartic Acid; Breast Neoplasms; Carbamoyl-Phosphate Synthase (Ammonia); Cell Line; Dihydroorotase; Drug Resistance; Female; Humans; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Uracil Nucleotides; Uridine | 1986 |
Effect of deoxycytidine on the in vitro response of human leukemia cells to inhibitors of de novo pyrimidine biosynthesis.
Topics: 3-Deazauridine; Amides; Aspartic Acid; Cell Division; Cell Line; Deoxycytidine; Deoxycytidine Kinase; Drug Interactions; Humans; Leukemia, Experimental; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Thymidine | 1987 |
Hamster cells with increased rates of DNA amplification, a new phenotype.
Topics: Amides; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Cell Line; Coformycin; Cricetinae; DNA; Drug Resistance; Gene Amplification; Genes; Kidney; Methotrexate; Mutation; Ouabain; Phenotype; Phosphonoacetic Acid; Pyrazoles; Ribonucleosides; Ribose; Tetrahydrofolate Dehydrogenase | 1987 |
[Current problems in medical virology. VI. Virostatics--what we need and what we have].
Topics: Acyclovir; Amantadine; Amides; Antiviral Agents; Guanidine; Guanidines; Guanine; Interferons; Methisazone; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Thymidine; Vidarabine; Virus Diseases | 1981 |
Effect of inhibitors of the de novo pyrimidine biosynthetic pathway on serum uridine levels in mice.
Topics: Amides; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Azauridine; Galactosamine; Liver; Male; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Uridine | 1981 |
Relationship between ribo- and deoxyribonucleotide concentrations and biological parameters in cultured Chinese hamster ovary cells.
Topics: Amides; Animals; Aspartic Acid; Cell Cycle; Cells, Cultured; Cricetinae; Cricetulus; Deoxyribonucleotides; Female; Mycophenolic Acid; Ovary; Phosphonoacetic Acid; Pyrazoles; Ribonucleosides; Ribonucleotides; Ribose; Thymidine | 1982 |
Kinetics of N-(phosphonacetyl)-L-aspartate and pyrazofurin depletion of pyrimidine ribonucleotide and deoxyribonucleotide pools and their relationship to nucleic acid synthesis in intact and permeabilized cells.
Topics: Amides; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Deoxyribonucleotides; DNA Replication; DNA, Neoplasm; Kinetics; Leukemia L1210; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Pyrazoles; Pyrimidine Nucleotides; Ribonucleosides; Ribonucleotides; Ribose; RNA, Neoplasm; Transcription, Genetic | 1982 |
Salvage of circulating pyrimidine nucleosides in the rat.
Topics: Amides; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Cytidine; Male; Phosphonoacetic Acid; Pyrazoles; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Rats; Ribonucleosides; Ribose; Tissue Distribution; Uridine | 1981 |
Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid.
Topics: Amides; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carcinoma; Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Lung Neoplasms; Mice; Neoplasms, Experimental; Orotic Acid; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose | 1981 |
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.
Topics: Adenosine Monophosphate; Amides; Antimetabolites, Antineoplastic; Aspartic Acid; Cell Cycle; Cells, Cultured; Chromosome Aberrations; DNA Damage; Gamma Rays; Humans; Male; Phosphonoacetic Acid; Pyrazoles; Ribonucleosides; Ribonucleotides; Ribose; RNA; Tumor Suppressor Protein p53 | 1996 |
Drug-resistant breast cancer cells frequently retain expression of a functional wild-type p53 protein.
Topics: Amides; Antineoplastic Agents; Aspartic Acid; Blotting, Western; Breast Neoplasms; Cell Cycle; Clone Cells; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Female; Flow Cytometry; Gene Expression; Genes, p53; Humans; Immunohistochemistry; Melphalan; Mitoxantrone; Neoplasm Proteins; Nuclear Proteins; Phosphonoacetic Acid; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Pyrazoles; Ribonucleosides; Ribose; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1996 |
A mutant of Sindbis virus that is resistant to pyrazofurin encodes an altered RNA polymerase.
Topics: Adenosine; Aedes; Amides; Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Cells, Cultured; Chick Embryo; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Fibroblasts; Guanosine; Models, Molecular; Mutation; Phenotype; Phosphonoacetic Acid; Protein Structure, Tertiary; Pyrazoles; Recombination, Genetic; Ribonucleosides; Ribose; Sindbis Virus; Virus Replication | 2000 |
Antipyrimidine effects of five different pyrimidine de novo synthesis inhibitors in three head and neck cancer cell lines.
Topics: Amides; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Biphenyl Compounds; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma, Squamous Cell; Cell Line, Tumor; Dihydroorotate Dehydrogenase; Head and Neck Neoplasms; Humans; Isoxazoles; Naphthoquinones; Orotate Phosphoribosyltransferase; Oxidoreductases Acting on CH-CH Group Donors; Phosphonoacetic Acid; Purine Nucleotides; Pyrazoles; Pyrimidine Nucleotides; Ribonucleosides; Ribose | 2018 |