phosphonoacetic acid and orotic acid

phosphonoacetic acid has been researched along with orotic acid in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19907 (70.00)18.7374
1990's3 (30.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Handschumacher, RE; Moyer, JD1
Colofiore, JR; Koutcher, JA; Martin, DS; Nord, LD; Stolfi, RL1
Nelson, J; Qureshi, IA; Vasudevan, S1
Cassady, JM; Jacobsen, LB; Morré, DJ; Putnam, JE; Sawick, DP1
Casper, ES; Martin, DS; Vale, K; Williams, LJ; Young, CW1
Cooney, DA; Jayaram, HN; Kensler, TW1
Kufe, DW; Loh, E1
Brinster, RL; Troike, DE1
Ardalan, B; Cooney, DA; Cysyk, RL; Han, N; Hankerson, JG; Harley, C; Jayaram, HN; Johnson, RK; Kensler, TW; Mutter, G; Reck, LJ1
Nelson, J; Qureshi, IA; Sarma, DS; Vasudevan, S1

Other Studies

10 other study(ies) available for phosphonoacetic acid and orotic acid

ArticleYear
Selective inhibition of pyrimidine synthesis and depletion of nucleotide pools by N-(phosphonacetyl)-L-aspartate.
    Cancer research, 1979, Volume: 39, Issue:8

    Topics: Animals; Aspartic Acid; Cells, Cultured; Female; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organophosphorus Compounds; Orotic Acid; Phosphonoacetic Acid; Pyrazoles; Pyrimidine Nucleotides; Pyrimidines; Ribonucleosides; Uridine

1979
Biochemical modulation of tumor cell energy: regression of advanced spontaneous murine breast tumors with a 5-fluorouracil-containing drug combination.
    Cancer research, 1992, Aug-01, Volume: 52, Issue:15

    Topics: 6-Aminonicotinamide; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methylthioinosine; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Orotic Acid; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate

1992
[Mechanism of the effect of serine and threonine on ammoniagenesis and biosynthesis of orotate in the mouse].
    Clinical and investigative medicine. Medecine clinique et experimentale, 1992, Volume: 15, Issue:2

    Topics: Adenine; Ammonia; Animals; Aspartic Acid; Cycloheximide; Male; Mice; Mice, Inbred ICR; Orotic Acid; Phosphonoacetic Acid; Serine; Threonine

1992
Pyrimidine nucleosides enhance the efficacy of inhibitors of pyrimidine biosynthesis in cultured hepatocellular carcinoma cells.
    Life sciences, 1988, Volume: 42, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Aspartic Acid; Cell Division; Cytidine; Liver Neoplasms, Experimental; Organophosphorus Compounds; Orotic Acid; Phosphonoacetic Acid; Pyrimidine Nucleosides; Pyrimidines; Rats; Tumor Cells, Cultured; Uridine

1988
Phase I and clinical pharmacological evaluation of biochemical modulation of 5-fluorouracil with N-(phosphonacetyl)-L-aspartic acid.
    Cancer research, 1983, Volume: 43, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Aspartic Acid; Blood Cell Count; Carcinoma; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Diseases; Humans; Male; Middle Aged; Organophosphorus Compounds; Orotic Acid; Phosphonoacetic Acid; Pyrimidines; Sarcoma

1983
Effects of acivicin and PALA, singly and in combination, on de novo pyrimidine biosynthesis.
    Advances in enzyme regulation, 1982, Volume: 20

    Topics: Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line; Isoxazoles; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nucleic Acids; Organophosphorus Compounds; Orotic Acid; Oxazoles; Phosphonoacetic Acid; Pyrimidines

1982
Synergistic effects with inhibitors of de novo pyrimidine synthesis, acivicin, and N-(phosphonacetyl)-L-aspartic acid.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Animals; Aspartic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxycytosine Nucleotides; Deoxyribonucleosides; Drug Synergism; Glycine; Isoxazoles; Leukemia L1210; Mice; Organophosphorus Compounds; Orotic Acid; Oxazoles; Phosphonoacetic Acid; Pyrimidines; Ribonucleosides

1981
De novo pyrimidine nucleotide synthesis in the preimplantation mouse embryo.
    Experimental cell research, 1981, Volume: 134, Issue:2

    Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Blastocyst; Mice; Morula; Orotic Acid; Phosphonoacetic Acid; Pyrimidine Nucleotides; Uridine

1981
Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid.
    Cancer research, 1981, Volume: 41, Issue:3

    Topics: Amides; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carcinoma; Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Lung Neoplasms; Mice; Neoplasms, Experimental; Orotic Acid; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose

1981
The effects of various inhibitors on the regulation of orotic acid excretion in sparse-fur mutant mice (spf/Y) deficient in ornithine transcarbamylase.
    Chemico-biological interactions, 1993, Volume: 89, Issue:1

    Topics: Adenine; Animals; Antimetabolites; Aspartic Acid; Creatinine; Cycloheximide; Injections, Intraperitoneal; Isoxazoles; Liver; Male; Mice; Mice, Mutant Strains; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Phosphonoacetic Acid

1993