phosphonoacetic acid has been researched along with cytidine triphosphate in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (33.33) | 18.7374 |
| 1990's | 12 (50.00) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kantrowitz, ER; Newton, CJ; Stevens, RC | 1 |
| Schachman, HK; Wente, SR | 1 |
| Kantrowitz, ER; Middleton, SA; Tauc, P; Vachette, P | 1 |
| Kantrowitz, ER; Newton, CJ | 1 |
| Eisenstein, E; Markby, DW; Schachman, HK | 1 |
| Kantrowitz, ER; Stebbins, JW; Zhang, Y | 1 |
| Markby, DW; Newell, JO; Schachman, HK | 1 |
| Corder, TS; Wild, JR | 1 |
| Hsuanyu, YC; Wedler, FC | 1 |
| Lahue, RS; Schachman, HK | 1 |
| Hervé, G; Jones, PT; Moody, MF; Tauc, P; Vachette, P | 1 |
| Foote, J; Schachman, HK | 1 |
| Schachman, HK; Wacks, DB | 1 |
| Allewell, NM; Lennick, M | 1 |
| Fetler, L; Hervé, G; Moody, MF; Tauc, P; Vachette, P | 1 |
| Durrani, FA; Rustum, YM; van Laar, JA | 1 |
| Kasperrs, GJ; Kazemier, KM; Noordhuis, P; Peters, GJ | 1 |
| Blough, HA; Grem, JL; Katsafanas, GC; Moss, B | 1 |
| Burns, BP; Hazell, SL; Mendz, GL | 1 |
| Allewell, NM; Hariharan, M | 1 |
| Kantrowitz, ER; Sakash, JB | 1 |
| Chan, RS; Kantrowitz, ER; Macol, CP; Sakash, JB; Tsuruta, H; West, JM | 1 |
| Cunin, R; Maes, D; Van Boxstael, S | 1 |
| Barahona, M; Hodges, M; Yaliraki, SN | 1 |
24 other study(ies) available for phosphonoacetic acid and cytidine triphosphate
| Article | Year |
|---|---|
Importance of a conserved residue, aspartate-162, for the function of Escherichia coli aspartate transcarbamoylase.
Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbamyl Phosphate; Computer Simulation; Cytidine Triphosphate; Escherichia coli; Kinetics; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Phosphonoacetic Acid; Structure-Activity Relationship | 1992 |
Different amino acid substitutions at the same position in the nucleotide-binding site of aspartate transcarbamoylase have diverse effects on the allosteric properties of the enzyme.
Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbamyl Phosphate; Cytidine Triphosphate; DNA Mutational Analysis; Histidine; Lysine; Phosphonoacetic Acid; Structure-Activity Relationship | 1991 |
Structural consequences of the replacement of Glu239 by Gln in the catalytic chain of Escherichia coli aspartate transcarbamylase.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamyl Phosphate; Cytidine Triphosphate; Escherichia coli; Glutamates; Glutamic Acid; Glutamine; Phosphonoacetic Acid; Protein Engineering; Structure-Activity Relationship; X-Ray Diffraction | 1990 |
Importance of domain closure for homotropic cooperativity in Escherichia coli aspartate transcarbamylase.
Topics: Adenosine Triphosphate; Alanine; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Cytidine Triphosphate; Enzyme Activation; Escherichia coli; Kinetics; Mutation; Phosphonoacetic Acid; Succinates | 1990 |
Heterotropic effectors promote a global conformational change in aspartate transcarbamoylase.
Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbamyl Phosphate; Cytidine Triphosphate; Escherichia coli; Kinetics; Mutation; Phosphonoacetic Acid; Protein Conformation | 1990 |
Importance of residues Arg-167 and Gln-231 in both the allosteric and catalytic mechanisms of Escherichia coli aspartate transcarbamoylase.
Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Catalysis; Cytidine Triphosphate; Escherichia coli; Glutamine; Kinetics; Mutation; Phosphonoacetic Acid; Protein Conformation | 1990 |
Cooperative binding of the bisubstrate analog N-(phosphonacetyl)-L-aspartate to aspartate transcarbamoylase and the heterotropic effects of ATP and CTP.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Cytidine Triphosphate; Cytosine Nucleotides; Escherichia coli; Kinetics; Macromolecular Substances; Organophosphorus Compounds; Phosphonoacetic Acid; Protein Binding; Radioisotope Dilution Technique; Tritium | 1989 |
Discrimination between nucleotide effector responses of aspartate transcarbamoylase due to a single site substitution in the allosteric binding site.
Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Cytidine Triphosphate; DNA Mutational Analysis; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Phosphonoacetic Acid; Structure-Activity Relationship; Uridine Triphosphate | 1989 |
Effectors of Escherichia coli aspartate transcarbamoylase differentially perturb aspartate binding rather than the T-R transition.
Topics: Adenosine Triphosphate; Algorithms; Aspartate Carbamoyltransferase; Aspartic Acid; Cytidine Triphosphate; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Phosphonoacetic Acid | 1988 |
Communication between polypeptide chains in aspartate transcarbamoylase. Conformational changes at the active sites of unliganded chains resulting from ligand binding to other chains.
Topics: Adenosine Triphosphate; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Cytidine Triphosphate; Escherichia coli; Kinetics; Macromolecular Substances; Phosphonoacetic Acid; Protein Conformation; Spectrophotometry | 1986 |
Quaternary structure changes in aspartate transcarbamylase studied by X-ray solution scattering. Signal transmission following effector binding.
Topics: Adenosine Triphosphate; Allosteric Site; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbamyl Phosphate; Cytidine Triphosphate; Escherichia coli; Macromolecular Substances; Phosphonoacetic Acid; X-Rays | 1985 |
Homotropic effects in aspartate transcarbamoylase. What happens when the enzyme binds a single molecule of the bisubstrate analog N-phosphonacetyl-L-aspartate?
Topics: Adenosine Triphosphate; Allosteric Site; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Cytidine Triphosphate; Escherichia coli; Kinetics; Nucleotides; Organophosphorus Compounds; Phosphonoacetic Acid; Thermodynamics | 1985 |
19F nuclear magnetic resonance studies of fluorotyrosine-labeled aspartate transcarbamoylase. Properties of the enzyme and its catalytic and regulatory subunits.
Topics: Adenosine Triphosphate; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Cytidine Triphosphate; Magnetic Resonance Spectroscopy; Phosphonoacetic Acid; Tyrosine | 1985 |
Changes in the hydrogen exchange kinetics of Escherichia coli aspartate transcarbamylase produced by effector binding and subunit association.
Topics: Adenosine Triphosphate; Aspartate Carbamoyltransferase; Aspartic Acid; Cytidine Triphosphate; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Phosphonoacetic Acid; Solvents | 1981 |
X-ray scattering titration of the quaternary structure transition of aspartate transcarbamylase with a bisubstrate analogue: influence of nucleotide effectors.
Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Cytidine Triphosphate; Models, Chemical; Nucleotides; Phosphonoacetic Acid; Protein Conformation; Scattering, Radiation; X-Rays | 1995 |
Antitumor activity of the weekly intravenous push schedule of 5-fluoro-2'-deoxyuridine +/- N-phosphonacetyl-L-aspartate in mice bearing advanced colon carcinoma 26.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Colonic Neoplasms; Cytidine Triphosphate; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Floxuridine; Infusions, Intravenous; Leukemia L1210; Mice; Mice, Inbred BALB C; Phosphonoacetic Acid; Uridine Triphosphate | 1993 |
Modulation of metabolism and cytotoxicity of cytosine arabinoside with N-(phosphon)-acetyl-L-aspartate in human leukemic blast cells and cell lines.
Topics: Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Aspartic Acid; Cytarabine; Cytidine Triphosphate; DNA, Neoplasm; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Leukemia; Phosphonoacetic Acid; Tumor Cells, Cultured; Uridine Triphosphate | 1996 |
Inhibition of vaccinia virus replication by N-(phosphonoacetyl)-L-aspartate: differential effects on viral gene expression result from a reduced pyrimidine nucleotide pool.
Topics: Antiviral Agents; Aspartic Acid; Cell Survival; Cytidine Triphosphate; DNA-Directed RNA Polymerases; Gene Expression Regulation, Viral; HeLa Cells; Humans; Kinetics; Macromolecular Substances; Phosphonoacetic Acid; Pyrimidine Nucleotides; RNA, Messenger; Transcription, Genetic; Uridine; Uridine Triphosphate; Vaccinia virus; Virus Replication | 1997 |
In situ properties of Helicobacter pylori aspartate carbamoyltransferase.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamyl Phosphate; Cytidine Triphosphate; Enzyme Inhibitors; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Maleates; Organophosphates; Phosphonoacetic Acid; Ribose; Stereoisomerism; Substrate Specificity; Succinic Acid; Temperature | 1997 |
Effects of the T-->R transition on the electrostatic properties of E. coli aspartate transcarbamylase.
Topics: Allosteric Regulation; Allosteric Site; Aspartate Carbamoyltransferase; Aspartic Acid; Cytidine Triphosphate; Databases, Factual; Escherichia coli; Hydrogen-Ion Concentration; Isoelectric Point; Malonates; Phosphonoacetic Acid; Protein Conformation; Statistical Distributions; Thermodynamics | 1998 |
The contribution of individual interchain interactions to the stabilization of the T and R states of Escherichia coli aspartate transcarbamoylase.
Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Catalytic Domain; Cytidine Triphosphate; Escherichia coli; Holoenzymes; Kinetics; Phosphonoacetic Acid | 2000 |
The role of intersubunit interactions for the stabilization of the T state of Escherichia coli aspartate transcarbamoylase.
Topics: Adenosine Triphosphate; Alanine; Allosteric Site; Aspartate Carbamoyltransferase; Aspartic Acid; Catalytic Domain; Chromatography, Ion Exchange; Cytidine Triphosphate; Enzyme Inhibitors; Escherichia coli; Ligands; Lysine; Models, Molecular; Mutation; Phosphonoacetic Acid; Protein Binding; Protein Structure, Tertiary; Scattering, Radiation; X-Rays | 2002 |
Aspartate transcarbamylase from the hyperthermophilic archaeon Pyrococcus abyssi. Insights into cooperative and allosteric mechanisms.
Topics: Adenosine Triphosphate; Allosteric Regulation; Allosteric Site; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Ammonia); Carbamyl Phosphate; Catalysis; Cytidine Triphosphate; Escherichia coli; Phosphonoacetic Acid; Pyrococcus abyssi; Recombinant Proteins; Uridine Triphosphate | 2005 |
Allostery and cooperativity in multimeric proteins: bond-to-bond propensities in ATCase.
Topics: Adenosine Triphosphate; Allosteric Regulation; Allosteric Site; Aspartate Carbamoyltransferase; Aspartic Acid; Catalytic Domain; Cytidine Triphosphate; Enzyme Stability; Models, Molecular; Phosphonoacetic Acid; Protein Multimerization; Protein Subunits; Substrate Specificity | 2018 |