phosphonoacetic acid and aphidicolin

phosphonoacetic acid has been researched along with aphidicolin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199019 (63.33)18.7374
1990's10 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (3.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Hall, JD; Wang, YS; Woodward, S1
Costa, JV; Marques, MI1
Kopnin, BP; Sokova, OI1
Nishiyama, H1
Hirokawa, H; Kanehiro, H; Kim, CI; Kobayashi, H; Matsumoto, K1
Birch, CJ; Doherty, RR; Gust, ID; Hayes, K; Tachedjian, G1
Carroll, RD; Haffey, ML; Matthews, JT; Stevens, JT1
Berlin, MS; Hall, JD; Pierpont, J; Rundlett, SE; Wang, YS; Woodward, S1
Johnson, EM; Wilcox, CL1
Cheng, YC; Li, JS1
Allaudeen, HS1
Cheng, YC; Frank, KB1
Maeno, K; Nishiyama, Y; Tsurumi, T; Yamamoto, N; Yoshida, S1
Bornkamm, GW; Daillie, J; Decaussin, G; Lenoir, GM; Ooka, T1
Maeno, K; Nishiyama, Y; Tsurumi, T1
Bouché, JP; Girard, M; Méchali, M; van der Werf, S1
Cox, GS; Park, KH1
Maeno, K; Nishiyama, Y; Yoshida, S1
Arens, M; Goto, Y; Hashimoto, T; Takahashi, T; Yamashita, T1
Honess, RW; O'Hare, P1
Bastow, KF; Cheng, YC; Derse, DD1
Aoki, H; Maeno, K; Nishiyama, Y; Tsurumi, T1
Larsson, A; Oberg, B; Wrååk, M1
Cammack, N; Gopal, R; Honess, RW; O'Hare, P; Purifoy, DJ; Young, D1
Chinchar, VG; Granoff, A1
Adler, SP; McVoy, MA1
Taddie, JA; Traktman, P1
Coen, DM; Digard, P; Staknis, D; Wobbe, KK1
Gao, L; Hwang, CB; Hwang, YT; Smith, JF1

Other Studies

30 other study(ies) available for phosphonoacetic acid and aphidicolin

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Use of suppressor analysis to identify DNA polymerase mutations in herpes simplex virus which affect deoxynucleoside triphosphate substrate specificity.
    Journal of virology, 1992, Volume: 66, Issue:3

    Topics: Aphidicolin; Deoxyribonucleotides; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Nucleic Acid Synthesis Inhibitors; Phenotype; Phosphonoacetic Acid; Simplexvirus; Substrate Specificity

1992
African swine fever virus-induced DNA polymerase is resistant to aphidicolin.
    Virology, 1992, Volume: 191, Issue:1

    Topics: African Swine Fever Virus; Aphidicolin; Cytarabine; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Kinetics; Phosphonoacetic Acid

1992
[Segments of Djungarian hamster chromosomes, specific for translocation of integration of amplified mdr1 genes, do not possess increased instability].
    Genetika, 1991, Volume: 27, Issue:10

    Topics: Animals; Antineoplastic Agents; Aphidicolin; Aspartic Acid; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes; Cricetinae; Floxuridine; Gene Amplification; Nucleic Acid Hybridization; Phosphonoacetic Acid; Translocation, Genetic

1991
[Target of herpes virus growth inhibitors].
    Uirusu, 1990, Volume: 40, Issue:1

    Topics: Alkaloids; Animals; Aphidicolin; Diterpenes; DNA Topoisomerases, Type I; DNA-Directed DNA Polymerase; Guanine; Herpesviridae; Kanamycin; Phosphonoacetic Acid; Prostaglandins

1990
Aphidicolin-resistant DNA polymerase of bacteriophage phi 29 APHr71 mutant is hypersensitive to phosphonoacetic acid and butylphenyldeoxyguanosine 5'-triphosphate.
    Virology, 1990, Volume: 178, Issue:1

    Topics: Amino Acid Sequence; Antiviral Agents; Aphidicolin; Bacteriophages; Deoxyguanine Nucleotides; Diterpenes; DNA Polymerase II; Drug Resistance; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Phosphonoacetic Acid

1990
Altered sensitivity to antiviral drugs of herpes simplex virus isolates from a patient with the acquired immunodeficiency syndrome.
    The Journal of infectious diseases, 1990, Volume: 162, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Aphidicolin; Deoxyguanosine; Diterpenes; Drug Resistance, Microbial; Female; Foscarnet; Herpes Simplex; Humans; Phosphonoacetic Acid; Simplexvirus

1990
In vitro mutagenesis of the herpes simplex virus type 1 DNA polymerase gene results in altered drug sensitivity of the enzyme.
    Journal of virology, 1989, Volume: 63, Issue:11

    Topics: Amino Acid Sequence; Antiviral Agents; Aphidicolin; Asparagine; Base Sequence; Diterpenes; DNA-Directed DNA Polymerase; Foscarnet; Genes, Viral; Genetic Vectors; HeLa Cells; Humans; Kinetics; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Probes; Phosphonoacetic Acid; Saccharomyces cerevisiae; Serine; Simplexvirus; Viral Structural Proteins

1989
Aphidicolin resistance in herpes simplex virus type I reveals features of the DNA polymerase dNTP binding site.
    Nucleic acids research, 1989, Nov-25, Volume: 17, Issue:22

    Topics: Amino Acid Sequence; Animals; Antiviral Agents; Aphidicolin; Base Sequence; Binding Sites; Deoxyribonucleotides; Diterpenes; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Genes, Viral; Molecular Sequence Data; Mutation; Phosphonoacetic Acid; Restriction Mapping; Simplexvirus; Vero Cells; Viral Plaque Assay; Viral Structural Proteins

1989
Characterization of nerve growth factor-dependent herpes simplex virus latency in neurons in vitro.
    Journal of virology, 1988, Volume: 62, Issue:2

    Topics: Acyclovir; Animals; Antigens, Viral; Aphidicolin; Cells, Cultured; Cytopathogenic Effect, Viral; Diterpenes; DNA Polymerase II; DNA Replication; DNA, Viral; Immunohistochemistry; Nerve Growth Factors; Neurons; Phosphonoacetic Acid; Rats; Simplexvirus; Virus Replication

1988
Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5'-GMP.
    Virus genes, 1988, Volume: 1, Issue:4

    Topics: Aphidicolin; Deoxyribonucleotides; Diterpenes; Foscarnet; Guanine Nucleotides; Guanosine Monophosphate; Herpesvirus 4, Human; Nucleic Acid Synthesis Inhibitors; Organophosphorus Compounds; Phosphonoacetic Acid; Protein Binding; Viral Proteins

1988
Distinctive properties of DNA polymerases induced by herpes simplex virus type-1 and Epstein-Barr virus.
    Antiviral research, 1985, Volume: 5, Issue:1

    Topics: Animals; Aphidicolin; Cell Line; Chromatography, DEAE-Cellulose; Diterpenes; DNA-Directed DNA Polymerase; Ethylmaleimide; Foscarnet; Herpesvirus 4, Human; Hot Temperature; Nucleic Acid Synthesis Inhibitors; Nucleosides; Phosphonoacetic Acid; Simplexvirus

1985
Mutually exclusive inhibition of herpesvirus DNA polymerase by aphidicolin, phosphonoformate, and acyclic nucleoside triphosphates.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:4

    Topics: Acyclovir; Antiviral Agents; Aphidicolin; Deoxyribonucleases; Diterpenes; Foscarnet; Guanosine Triphosphate; Kinetics; Nucleic Acid Synthesis Inhibitors; Organophosphorus Compounds; Phosphonoacetic Acid; Simplexvirus

1985
Drug-resistant mutants of herpes simplex virus type 2 with a mutator or antimutator phenotype.
    Microbiology and immunology, 1985, Volume: 29, Issue:4

    Topics: Animals; Aphidicolin; Cell Line; Chlorocebus aethiops; Diterpenes; Drug Resistance, Microbial; Mutation; Phenotype; Phosphonoacetic Acid; Simplexvirus

1985
Epstein-Barr virus-specific DNA polymerase in virus-nonproducer Raji cells.
    Journal of virology, 1986, Volume: 58, Issue:2

    Topics: Antigens, Viral; Aphidicolin; Butyrates; Butyric Acid; Cell Line; Diterpenes; DNA Replication; DNA-Directed DNA Polymerase; Enzyme Induction; Foscarnet; Herpesvirus 4, Human; Humans; Phosphonoacetic Acid; Substrate Specificity; Tetradecanoylphorbol Acetate; Virus Replication

1986
A single-base change within the DNA polymerase locus of herpes simplex virus type 2 can confer resistance to aphidicolin.
    Journal of virology, 1987, Volume: 61, Issue:2

    Topics: Animals; Aphidicolin; Base Sequence; Cell Line; Diterpenes; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Genes; Genes, Viral; Mutation; Phenotype; Phosphonoacetic Acid; Simplexvirus

1987
Involvement of both DNA polymerases alpha and gamma in the replication of adenovirus deoxyribonucleic acid in vitro.
    Virology, 1980, Jul-15, Volume: 104, Issue:1

    Topics: Adenoviruses, Human; Aphidicolin; Arabinofuranosylcytosine Triphosphate; Cell Nucleus; Cell-Free System; Dideoxynucleotides; Diterpenes; DNA Polymerase I; DNA Polymerase III; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; HeLa Cells; Humans; Phosphonoacetic Acid; Thymine Nucleotides; Vidarabine Phosphate

1980
Induction of alkaline phosphatase and the glycoprotein hormone alpha subunit in HeLa cells by inhibitors of DNA polymerase.
    Archives of biochemistry and biophysics, 1982, Volume: 216, Issue:1

    Topics: Alkaline Phosphatase; Aphidicolin; Cycloheximide; Dactinomycin; Diterpenes; DNA Polymerase II; DNA Replication; Enzyme Induction; Foscarnet; Glycoprotein Hormones, alpha Subunit; Glycoproteins; HeLa Cells; Hormones; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Organophosphorus Compounds; Peptide Fragments; Phosphonoacetic Acid

1982
Characterization of human cytomegalovirus-induced DNA polymerase and the associated 3'-to-5', exonuclease.
    Virology, 1983, Jan-30, Volume: 124, Issue:2

    Topics: Ammonium Sulfate; Aphidicolin; Cytomegalovirus; Diterpenes; DNA-Directed DNA Polymerase; DNA, Single-Stranded; Ethylmaleimide; Exodeoxyribonuclease V; Exodeoxyribonucleases; Hydrogen-Ion Concentration; Phosphonoacetic Acid; Substrate Specificity; Vidarabine Phosphate

1983
Characterization of hepatitis B virus DNA polymerase.
    Japanese journal of medical science & biology, 1984, Volume: 37, Issue:1

    Topics: Aphidicolin; Dideoxynucleotides; Diterpenes; DNA-Directed DNA Polymerase; Ethylmaleimide; Formaldehyde; Foscarnet; Hepatitis B virus; Hot Temperature; Nucleic Acid Synthesis Inhibitors; Phosphonoacetic Acid; Thymine Nucleotides; Vidarabine Phosphate; Virion

1984
Evidence for a herpesvirus saimiri-specified DNA polymerase activity which is aphidicolin-resistant and phosphonoacetate-sensitive.
    The Journal of general virology, 1983, Volume: 64, Issue:Pt 5

    Topics: Antiviral Agents; Aphidicolin; Diterpenes; DNA Replication; DNA, Viral; Drug Resistance, Microbial; Herpesvirus 2, Saimiriine; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphorus Compounds; Phosphonoacetic Acid; Virus Replication

1983
Susceptibility of phosphonoformic acid-resistant herpes simplex virus variants to arabinosylnucleosides and aphidicolin.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:6

    Topics: Antiviral Agents; Aphidicolin; Arabinonucleosides; Coformycin; Diterpenes; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Pentostatin; Phosphonoacetic Acid; Simplexvirus; Thymidine; Thymidine Kinase; Vidarabine

1983
Identification of DNA polymerase(s) involved in the repair of viral and cellular DNA in herpes simplex virus type 2-infected cells.
    Virology, 1983, Volume: 129, Issue:2

    Topics: Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA; DNA Polymerase I; DNA Repair; DNA, Viral; Humans; Phosphonoacetic Acid; Simplexvirus

1983
Effect of aphidicolin on DNA synthesis in HSV-1 infected and uninfected Vero cells.
    Antiviral research, 1983, Volume: 3, Issue:2

    Topics: Animals; Aphidicolin; Cell Line; Chlorocebus aethiops; Diterpenes; DNA; DNA, Viral; Foscarnet; Phosphonoacetic Acid; Simplexvirus

1983
Single mutations at many sites within the DNA polymerase locus of herpes simplex viruses can confer hypersensitivity to aphidicolin and resistance to phosphonoacetic acid.
    The Journal of general virology, 1984, Volume: 65 ( Pt 1)

    Topics: Antiviral Agents; Aphidicolin; Diterpenes; DNA Polymerase II; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Genetic Markers; Mutation; Organophosphorus Compounds; Phenotype; Phosphonoacetic Acid; Recombination, Genetic; Simplexvirus; Virus Cultivation

1984
Isolation and characterization of a frog virus 3 variant resistant to phosphonoacetate: genetic evidence for a virus-specific DNA polymerase.
    Virology, 1984, Oct-30, Volume: 138, Issue:2

    Topics: Animals; Aphidicolin; Diterpenes; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Iridoviridae; Phosphonoacetic Acid; Ranidae; Viral Proteins; Virus Replication

1984
Human cytomegalovirus DNA replicates after early circularization by concatemer formation, and inversion occurs within the concatemer.
    Journal of virology, 1994, Volume: 68, Issue:2

    Topics: Aphidicolin; Cells, Cultured; Chromosome Inversion; Cycloheximide; Cytomegalovirus; Deoxyribonucleases, Type II Site-Specific; DNA Replication; DNA, Circular; DNA, Recombinant; DNA, Viral; Electrophoresis, Agar Gel; Fibroblasts; Gamma Rays; Genome, Viral; Humans; Isotope Labeling; Micrococcal Nuclease; Nucleic Acid Conformation; Phosphonoacetic Acid

1994
Genetic characterization of the vaccinia virus DNA polymerase: cytosine arabinoside resistance requires a variable lesion conferring phosphonoacetate resistance in conjunction with an invariant mutation localized to the 3'-5' exonuclease domain.
    Journal of virology, 1993, Volume: 67, Issue:7

    Topics: Animals; Aphidicolin; Base Sequence; Cell Line; Chlorocebus aethiops; Cytarabine; DNA-Directed DNA Polymerase; Drug Resistance; Exonucleases; In Vitro Techniques; L Cells; Mice; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oligodeoxyribonucleotides; Phosphonoacetic Acid; Restriction Mapping; Sequence Alignment; Species Specificity; Structure-Activity Relationship; Vaccinia virus; Virus Replication

1993
Unusual regulation of expression of the herpes simplex virus DNA polymerase gene.
    Journal of virology, 1993, Volume: 67, Issue:9

    Topics: Animals; Aphidicolin; DNA Replication; DNA-Directed DNA Polymerase; Ganciclovir; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Viral; Genes, pol; Hydroxyurea; Kinetics; Phosphonoacetic Acid; Protein Biosynthesis; RNA, Messenger; RNA, Viral; Simplexvirus; Thymidine Kinase; Transcription, Genetic; Vero Cells

1993
Mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene can confer altered drug sensitivities.
    Virology, 1998, Jul-05, Volume: 246, Issue:2

    Topics: Amino Acid Sequence; Animals; Antiviral Agents; Aphidicolin; Binding Sites; Chlorocebus aethiops; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Enzyme Inhibitors; Exodeoxyribonuclease V; Exodeoxyribonucleases; Genes, pol; Genes, Viral; Herpesvirus 1, Human; Histidine; Humans; Molecular Sequence Data; Mutation; Nucleosides; Open Reading Frames; Phosphonoacetic Acid; Protein Structure, Secondary; Recombination, Genetic; Tyrosine; Vero Cells; Viral Proteins

1998