phosphatidylcholines has been researched along with tryptophan in 232 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (tryptophan) | Trials (tryptophan) | Recent Studies (post-2010) (tryptophan) |
|---|---|---|---|---|---|
| 101 | 1 | 21 | 32,762 | 936 | 7,183 |
| 32,204 | 443 | 5,593 | 32,762 | 936 | 7,183 |
| Protein | Taxonomy | phosphatidylcholines (IC50) | tryptophan (IC50) |
|---|---|---|---|
| Myeloperoxidase | Homo sapiens (human) | 2.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (18.10) | 18.7374 |
| 1990's | 66 (28.45) | 18.2507 |
| 2000's | 76 (32.76) | 29.6817 |
| 2010's | 41 (17.67) | 24.3611 |
| 2020's | 7 (3.02) | 2.80 |
| Authors | Studies |
|---|---|
| Breukink, E; de Kruijff, B; Demel, RA; Kuipers, OP; Siezen, RJ; van Dalen, A; van Kraaij, C | 1 |
| Epand, RF; Epand, RM; Sayer, BG | 2 |
| Domanov, Y; Kinnunen, PK; Kontinen, VP; Pietiäinen, M; Sood, R | 1 |
| Hori, R; Inui, KI; Kaneda, A; Muranishi, S; Tabara, K | 1 |
| Feigenson, GW; Kingsley, PB; Meers, PR | 1 |
| Feigenson, GW; London, E | 1 |
| Hirayama, O; Maenaka, K; Matsuda, H; Takatsuka, H; Takeda, H | 1 |
| Hili, MJ | 1 |
| Cox, KJ; Ho, C; Lombardi, JV; Stubbs, CD | 1 |
| Blastó, K; Grinfeldt, AE; Korchev, YE; Lev, AA; Schagina, LV | 1 |
| Kagiwada, S; Murata, M; Ohnishi, S; Suzuki, A; Takahashi, S | 1 |
| Chattopadhyay, A; McNamee, MG | 1 |
| Goundis, D; Kalb, E; Stankowski, S; Wey, J | 1 |
| Brumfeld, V; Lester, DS | 1 |
| de Kroon, AI; de Kruijff, B; Keller, RC; Killian, JA; Struyvé, M; Tommassen, J | 1 |
| De Gier, J; De Kroon, AI; De Kruijff, B; Soekarjo, MW | 1 |
| Bolen, EJ; Holloway, PW | 1 |
| Butko, P; Nemecz, G; Scallen, TJ; Schroeder, F | 1 |
| Jordan, MK; Weinberg, RB | 1 |
| de Kruijff, B; Keur, S; Killian, JA; Timmermans, JW | 1 |
| Burger, KN; de Kruijff, B; Killian, JA | 1 |
| Stark, G; Strässle, M; Wilhelm, M | 1 |
| Nir, S; Parente, RA; Szoka, FC | 1 |
| Buck, HM; Dubois, JE; Kremers, JA; Meulendijks, GH; Nielen, RJ; Sonderkamp, T | 1 |
| Scarlata, SF | 1 |
| Ericsson, K; Forssell, LG; Hellström, A; Winblad, B | 1 |
| Eftink, MR; Hagaman, KA; Krstenansky, JL; McLean, LR; Owen, TJ | 1 |
| Auclair, F; Mantsch, HH; Surewicz, K; Surewicz, WK | 1 |
| Goñi, FM; Macarulla, JM; Valpuesta, JM | 1 |
| Cookson, JC | 1 |
| Leathwood, PD | 1 |
| East, JM; Froud, RJ; Lee, AG; Rooney, EK | 1 |
| Berkhout, TA; de Kruijff, B; Marsh, D; Rietveld, A; Roenhorst, A | 1 |
| Berkhout, TA; de Kruijff, B; Rietveld, A | 1 |
| Candide, C; Mazière, C; Mazière, JC; Morlière, P; Reyftmann, JP; Salmon, S; Santus, R | 1 |
| Fleischer, S; McIntyre, JO; Sandermann, H | 1 |
| Batenburg, AM; de Kruijff, B; Hibbeln, JC | 1 |
| Jung, G; Sawyer, WH; Voges, KP | 1 |
| Lerer, B | 1 |
| Gulik-Krzywicki, T; Iwatsubo, M; Luzzati, V; Ranck, JL; Shechter, E | 1 |
| Edelhoch, H; Schneider, AB | 1 |
| Pownall, HJ; Smith, LC | 1 |
| Whittaker, VP | 1 |
| Aune, KC; Gallagher, JG; Gotto, AM; Morrisett, JD | 1 |
| Weigl, J | 1 |
| Wilcox, M | 1 |
| Abita, JP; Bonsen, PP; de Haas, GH; Lazdunski, M; Pieterson, WA | 1 |
| Wells, MA | 1 |
| Iwanaga, S; Kawauchi, S; Samejima, Y; Suzuki, T | 1 |
| Hefti, F; Melamed, E; Wurtman, RJ | 1 |
| Wurtman, RJ | 1 |
| Berkhout, TA; Visser, AJ; Wirtz, KW | 1 |
| Assmann, G; Lievens, MJ; Rosseneu, M; Schmitz, G; Van Tornout, P | 1 |
| Georghiou, S; Mukhopadhyay, AK; Thompson, M | 1 |
| Curatola, G; Zolese, G | 1 |
| Chattopadhyay, A; Mukherjee, S | 1 |
| Mosior, M; Newton, AC | 1 |
| Thumser, AE; Wilton, DC | 1 |
| Iwamoto, M; Nakamura, M; Ohno-Iwashita, Y; Sekino, N | 1 |
| Das, PK; Podder, SK; Ramalingam, TS | 1 |
| East, JM; Khan, YM; Lee, AG; Starling, AP | 1 |
| Gryczynski, I; Johnson, ML; Laczko, G; Lakowicz, JR; Wiczk, W | 1 |
| Filthuth, E; Griffith, OH; Jain, MK; Volwerk, JJ | 1 |
| Glaser, M; Naisbitt, GH; Vernon, LP; Wang, F | 1 |
| Mel, SF; Stroud, RM | 1 |
| Hagaman, KA; McLean, LR | 1 |
| Mealy, T; Meers, P | 1 |
| de Planque, MR; Greathouse, DV; Killian, JA; Koeppe, RE; Lindblom, G; Salemink, I | 1 |
| Kaul, P; Lala, AK; Ratnam, PB | 1 |
| Balasubramanian, D; Sharma, Y; Uma, L | 1 |
| Helmkamp, GM; Tremblay, JM; Voziyan, PA; Yarbrough, LR | 1 |
| Kleinschmidt, JH; Tamm, LK | 1 |
| Kiyota, T; Lee, S; Sugihara, G | 1 |
| Acuña, AU; Amat-Guerri, F; Mateo, CR; Souto, AA | 1 |
| Ben-Efraim, I; Shai, Y | 1 |
| Ladokhin, AS; Selsted, ME; White, SH | 1 |
| Cui, D; Lin, Q; Wang, Q | 1 |
| Lee, S; Nishimoto, E; Ohno, M; Oishi, O; Sugihara, G; Yamashita, S | 1 |
| Follenius-Wund, A; Freyssinet, JM; Gérard, D; Piémont, E; Pigault, C | 1 |
| Gray, C; Tamm, LK; Tatulian, SA; Wharton, SA | 1 |
| Vogel, H | 1 |
| Chattopadhyay, A; Mukherjee, S; Rawat, SS; Rukmini, R; Sudha, S | 1 |
| Ho, C; Stubbs, CD | 1 |
| Butko, P; Huang, F; Pusztai-Carey, M; Surewicz, WK | 1 |
| Anantharamaiah, GM; Gazzara, JA; Lund-Katz, S; Palgunachari, MN; Phillips, MC; Segrest, JP; Snow, JW | 1 |
| Chattopadhyay, A; Ghosh, AK; Rukmini, R | 1 |
| Arni, RK; Bortoleto, RK; de Oliveira, AH; Ruller, R; Ward, RJ | 1 |
| Brenner, RR; Córsico, B; Garda, HA; Toledo, JD; Tricerri, A | 1 |
| Kosk-Kosicka, D; Lopez, MM | 1 |
| Jelokhani-Niaraki, M; Kodama, H; Kondo, M; Nakashima, K | 1 |
| Axelsen, PH; Hristova, K; Ladokhin, AS; Silvestro, L; White, SH; Wimley, WC | 1 |
| Brochon, JC; Maget-Dana, R; Mangavel, C; Reynaud, JA; Sy, D; Tauc, P | 1 |
| Casals, C; Cruz, A; Marsh, D; Pérez-Gil, J; Plasencia, I | 1 |
| Cajal, Y; Dodia, C; Fisher, AB; Jain, MK | 1 |
| Baker, SF; Othman, R; Wilton, DC | 1 |
| Joseph, M; Nagaraj, R | 1 |
| Abad, C; Pascal, J; Pérez-Payá, E; Salom, D | 1 |
| Hof, M | 1 |
| Gawrisch, K; White, SH; Wimley, WC; Yau, WM | 1 |
| Le Guernevé, C; Marion, D; Seigneuret, M | 1 |
| Collier, RJ; London, E; Malenbaum, SE | 1 |
| Chattopadhyay, A; Lala, AK; Raja, SM; Rawat, SS | 1 |
| Min, X; Yang, F; Zhang, X | 1 |
| Arora, A; Gupta, CM; Puri, V | 1 |
| Gallay, J; Lewit-Bentley, A; Sopkova, J; Takahashi, M; Vincent, M | 1 |
| McIntosh, TJ; Simon, SA; Voglino, L | 1 |
| Aguilar, MI; Lee, TH; Mozsolits, H; Perlmutter, P; Wirth, HJ | 1 |
| Cramer, WA; Lindeberg, M; Zakharov, SD | 1 |
| Başaran, N; Doebler, RW; Goldston, H; Holloway, PW | 1 |
| Ladokhin, AS | 1 |
| Andersen, OS; Greathouse, DV; Hatchett, J; Jude, AR; Koeppe, RE; Providence, LL | 1 |
| Davidson, WS; Maiorano, JN | 1 |
| White, SH; Wimley, WC | 1 |
| Oren, Z; Shai, Y | 1 |
| Clayton, AH; Sawyer, WH | 1 |
| Avdulov, NA; Chochina, SV; Igbavboa, U; Wood, WG | 1 |
| Loeb-Hennard, C; McIntyre, JO | 1 |
| de Kruijff, B; de Planque, MR; Goormaghtigh, E; Greathouse, DV; Killian, JA; Koeppe , RE; Kruijtzer, JA; Liskamp, RM | 1 |
| Blazyk, J; Epand, RF; Epand, RM; Hammer, J; Kari, UP; Klein, J; Maloy, WL; Wiegand, R | 1 |
| Dufourcq, J; Gallay, J; Siffert, O; Talbot, JC; Thiaudière, E; Vincent, M | 1 |
| Hemminga, MA; Meijer, AB; Spruijt, RB; Wolfs, CJ | 1 |
| Andersen, NH; Fesinmeyer, RM; Neidigh, JW; Prickett, KS | 1 |
| Arrese, EL; Soulages, JL | 1 |
| Subbaiah, PV; Wang, K | 1 |
| Heyer, AG; Hincha, DK; Popova, AV | 1 |
| Kinnunen, PK; Zhao, H | 1 |
| Furuya, T; Kiyota, T; Lee, S; Matsutani, M; Shigematsu, D; Sugihara, G; Yamashita, S | 1 |
| Killian, JA; Koeppe, RE; Strandberg, E; van der Wel, PC | 1 |
| Almeida, PF; Birkbeck, TH; Pokorny, A | 1 |
| de Kroon, AI; de Kruijff, B; Killian, JA; Kol, MA; Rijkers, DT; van Laak, AN | 1 |
| Bonev, BB; de Planque, MR; Demmers, JA; Greathouse, DV; Killian, JA; Koeppe, RE; Separovic, F; Watts, A | 1 |
| Beers, SA; Buckland, AG; Gelb, MH; Giles, N; Wilton, DC | 1 |
| Aliste, MP; MacCallum, JL; Tieleman, DP | 1 |
| Aguilar, MI; Blazyk, J; Hammer, J; Jin, Y; Mozsolits, H; Zhang, Y; Zhu, F; Zmuda, E | 1 |
| Caputo, GA; Lew, S; London, E | 1 |
| Clark, EH; East, JM; Lee, AG | 1 |
| Brattwall, CE; Lincoln, P; Nordén, B | 1 |
| East, JM; Lee, AG; Powl, AM | 1 |
| Bravo, A; Gómez, I; Miranda-CassoLuengo, R; Muñoz-Garay, C; Rausell, C; Rudiño-Piñera, E; Soberón, M | 1 |
| Apitz-Castro, RJ; Berg, OG; Jain, MK; Yu, BZ | 1 |
| Roberts, MF; Wehbi, H; Zhang, X | 1 |
| Christiaens, B; Goethals, M; Grooten, J; Joliot, A; Prochiantz, A; Reusens, M; Rosseneu, M; Vandekerckhove, J | 1 |
| Esbjörner, EK; Goksör, M; Lincoln, P; Nordén, B; Persson, D; Thorén, PE | 1 |
| Anantharamaiah, GM; Epand, RF; Epand, RM; Melacini, G; Palgulachari, MN; Sayer, BG; Segrest, JP | 1 |
| Byron, O; Gilbert, R; Mitchell, T; Nöllmann, M; Sferrazza, M | 1 |
| Bo, T; Riekkola, ML; Wiedmer, SK | 1 |
| Caputo, GA; London, E | 1 |
| Chattopadhyay, A; Kelkar, DA; Rawat, SS | 1 |
| Lincoln, P; Nordén, B; Persson, D; Thorén, PE | 1 |
| Anantharamaiah, GM; Chaddha, M; Datta, G; Epand, RF; Epand, RM; Sayer, BG | 1 |
| Chattopadhyay, A; Raghuraman, H | 1 |
| Constantinescu, I; Lafleur, M | 1 |
| de Kruijff, B; Ganchev, DN; Killian, JA; Rijkers, DT; Snel, MM | 1 |
| Hincha, DK; Popova, AV | 1 |
| Higuchi, H; Kamio, Y; Kaneko, J; Monma, N; Nguyen, VT | 1 |
| Butko, P; Manceva, SD; Pusztai-Carey, M; Russo, PS | 1 |
| Hayashibara, M; London, E | 1 |
| Chupin, V; de Kruijff, B; Killian, JA; Meeldijk, H; Rijkers, DT; van Duyl, BY; Verkleij, AJ | 1 |
| Chen, J; Pang, Y; Wu, P; Zhu, H | 1 |
| Brown, RE; Kanack, AT; Malakhova, ML; Malinina, L; Patel, DJ; Pike, HM | 1 |
| Kinne, RK; Raja, MM | 1 |
| Baleux, F; Beswick, V; Coïc, YM; de Foresta, B; Gallay, J; Mousson, F; Neumann, JM; Vincent, M | 1 |
| Contera, SA; de Planque, MR; Lemaître, V; Ryan, JF; Watts, A | 1 |
| Hemminga, MA; Koehorst, RB; Spruijt, RB; Vos, WL | 1 |
| Jensen, MØ; Nielsen, CH; Petersen, FN | 1 |
| Axelsen, PH; Haque, ME; Koppaka, V; Lentz, BR | 1 |
| Bufali, S; Domazou, AS; Luisi, PL; Stano, P | 1 |
| Assi, F; Herbig, ME; Merkle, HP; Textor, M | 1 |
| Kemper, B; Ozalp, C; Szczesna-Skorupa, E | 1 |
| Basova, LV; Belikova, NA; Kagan, VE; Kapralov, AA; Kurnikov, IV; Osipov, AN; Peterson, J; Potapovich, MV; Tyurin, VA; Vladimirov, YA | 1 |
| Caesar, CE; Esbjörner, EK; Lincoln, P; Nordén, B | 1 |
| Castanho, MA; Johannes, L; Pina, DG | 1 |
| Chattopadhyay, A; Kelkar, DA | 1 |
| Hamdan, R; Maiti, SN; Schroit, AJ | 1 |
| East, JM; Jittikoon, J; Lee, AG | 1 |
| Esbjörner, EK; Gräslund, A; Lincoln, P; Nordén, B; Oglecka, K | 1 |
| Bonev, B; Breukink, E; Carey, S; Chan, WC; Narbad, A; Parisot, J | 1 |
| Basova, LV; Bayir, H; Belikova, NA; Jiang, J; Kagan, VE; Kapralov, AA; Kurnikov, IV; Tyurin, VA; Tyurina, YY; Vladimirov, YA; Vlasova, II; Zhao, Q | 1 |
| Fedorov, A; Hemminga, MA; Hesselink, RW; Prieto, M | 1 |
| Acasandrei, A; Gazdaru, D; Georgescu, R; Macri, BM; Nae, M; Radu, M | 1 |
| Gawrisch, K; Mitchell, DC; Niu, SL; Soubias, O | 1 |
| Askou, HJ; Fojan, P; Jakobsen, RN | 1 |
| Baumgaertner, A; Hemminga, MA; Schor, M; Tieleman, DP; Vos, WL | 1 |
| Esser, J; Fischer, L; Hofmann, B; Provost, P; Rådmark, O; Rakonjac, M; Samuelsson, B; Schneider, G; Steinhilber, D | 1 |
| Bianchi, A; D'Alessio, V; D'Errico, G; Merola, M; Notomista, E; Picone, D; Spadaccini, R | 1 |
| Krishnakumar, SS; London, E; Shahidullah, K | 1 |
| D'Errico, G; Falanga, A; Galdiero, M; Galdiero, S; Pedone, C; Vitiello, G; Vitiello, M | 1 |
| Becker, HC; Lignell, M | 1 |
| Al-Rawi, A; Chen, J; Cook, GA; Gao, J; Herrera, AI; Iwamoto, T; Prakash, O; Tomich, JM | 1 |
| Eu, YJ; Jung, HH; Jung, HJ; Kim, HH; Kim, JI; Lee, CW; Lee, JY; Lee, S; Milescu, M; Swartz, KJ | 1 |
| Fuchs, PF; Monticelli, L; Tieleman, DP | 1 |
| Celinski, K; Cichoz-Lach, H; Konturek, PC; Konturek, SJ; Slomka, M | 1 |
| Garda, HA; Prieto, ED | 1 |
| Bustad, HJ; Halskau, O; Martinez, A; Underhaug, J | 1 |
| Rhee, EP; Thadhani, R | 1 |
| Angstmann, CN; Breit, SN; Brown, LJ; Curmi, PM; Goodchild, SC | 1 |
| Grant, CV; Greathouse, DV; Koeppe, RE; Opella, SJ; Rankenberg, JM; Vostrikov, VV | 1 |
| Herman, P; Kacirova, M; Obsil, T; Obsilova, V; Rezabkova, L; Stepanek, M; Sulc, M; Vecer, J | 1 |
| Kyrychenko, A; Ladokhin, AS; Tobias, DJ | 1 |
| Homma, M; Nomura, F; Takahashi, T; Takiguchi, K; Tanaka-Takiguchi, Y; Yokoyama, Y | 1 |
| Amoussouvi, A; Haralampiev, I; Herrmann, A; Stöckl, M; Wietek, J | 1 |
| de Messieres, M; Jiang, Z; Lee, JC | 1 |
| Chattopadhyay, A; Chaudhuri, A; Haldar, S; Koeppe, RE; Sun, H | 1 |
| Brzozowski, T; Celinski, K; Cichoz-Lach, H; Konturek, PC; Konturek, SJ; Korolczuk, A; Slomka, M | 1 |
| Altgärde, N; Carlsson, N; Kunze, A; Nordén, B; Rydberg, HA; Svedhem, S | 1 |
| Gomez-Mendoza, M; Marin, ML; Miranda, MA | 1 |
| Dhanasekaran, P; Hata, M; Lund-Katz, S; Mizuguchi, C; Nickel, M; Okuhira, K; Phillips, MC; Saito, H | 1 |
| Alves, ID; Blanchet, M; Burlina, F; Castano, S; Chaignepain, S; Henry, S; Jobin, ML; Lecomte, S; Manigand, C; Sagan, S | 1 |
| Johnson, MA; Petrache, HI; Ray, BD; Wassall, SR | 1 |
| Burns, KE; Robinson, MK; Thévenin, D | 1 |
| Booth, IR; Edwards, MD; Galbiati, H; Miller, S; Rasmussen, A; Rasmussen, T; Singh, S | 1 |
| Jas, GS; Kuczera, K; Lee, BL; Middaugh, CR | 1 |
| Diederichsen, U; Pahlke, DM | 1 |
| Esteras, R; Fernandez-Prado, R; Gonzalez-Parra, E; Gracia-Iguacel, C; Ortiz, A; Perez-Gomez, MV; Sanchez-Niño, MD; Sanz, AB | 1 |
| Chadeau-Hyam, M; Chatzi, L; Keski-Rahkonen, P; Kogevinas, M; Nawrot, T; Pizzi, C; Plusquin, M; Richiardi, L; Robinot, N; Robinson, O; Scalbert, A; Sunyer, J; Vermeulen, R; Vineis, P; Vrijheid, M | 1 |
| Gazit, E; Kolusheva, S; Král, P; Rehak, P; Shaham-Niv, S; Zaguri, D | 1 |
| Bose, D; Chakrabarti, A; Giri, RP; Mukhopadhyay, MK; Sarkar, S | 1 |
| Bettati, S; Catinella, S; Marchetti, M; Pioselli, B; Ronda, L; Salomone, F | 1 |
| Chattopadhyay, A; Koeppe, RE; Pal, S | 1 |
| Chabrun, F; Chao de la Barca, JM; Dieu, X; Jousset, N; Palmiere, C; Prunier-Mirabeau, D; Reynier, P; Rougé-Maillart, C; Rousseau, G; Simard, G; Teresiński, G | 1 |
| Auriola, S; Hanhineva, K; Heinonen, S; Jääskeläinen, T; Jokkala, J; Kärkkäinen, O; Laivuori, H; Lehtonen, M; Litonius, K | 1 |
| Anderson, CM; Cardenas, A; Elber, R; Webb, LJ | 1 |
| Backman, APE; Halin, J; Kjellberg, MA; Mattjus, P; Möuts, A; Nurmi, H | 1 |
| Ahmed, IA; DeGrado, WF; Gai, F; Jo, H; Kratochvil, HT; Zhang, K | 1 |
| Ansari, MZ; Swaminathan, R | 1 |
| Antonio de Almeida Pinto, L; Cardoso Dos Santos, M; da Costa Cabrera, D; de Lima, VR; Gonçalves Dal-Bó, A; Roberto Sant'Anna Cadaval Junior, T; Silva de Farias, B | 1 |
| Jiaranaikulwanitch, J; Jiranusornkul, S; Saenjum, C; Vajragupta, O; Wongrattanakamon, P; Yooin, W | 1 |
| Baba, T; Kanai, R; Kikkawa, M; Kosako, H; Miyazaki, T; Nagata, S; Nakagawa, A; Narita, H; Nishino, K; Onishi, E; Sakuragi, T; Toyoshima, C; Tsutsumi, A | 1 |
| Bai, Y; Chen, Y; Cheng, B; Liu, Y; Xu, S; Yang, X | 1 |
| Ding, W; Pang, Y; Yang, N; Zan, M; Zhang, L; Zheng, Y | 1 |
| Amigot-Sánchez, R; García-Linares, S; García-Montoya, C; Gorše, A; Heras-Márquez, D; Martínez-Del-Pozo, Á; Palacios-Ortega, J; Slotte, JP | 1 |
4 review(s) available for phosphatidylcholines and tryptophan
| Article | Year |
|---|---|
Drug treatment of bipolar depression and mania.
Topics: Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Bromocriptine; Carbamazepine; Cholinesterase Inhibitors; Clonidine; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium; Monoamine Oxidase Inhibitors; Phosphatidylcholines; Tryptophan; Valproic Acid; Verapamil | 1985 |
Alternative therapies for bipolar disorder.
Topics: Ascorbic Acid; Bipolar Disorder; Bupropion; Carbamazepine; Choline; Clonazepam; Clonidine; Clorgyline; Demeclocycline; Fenfluramine; Humans; Methylene Blue; Phosphatidylcholines; Physostigmine; Propiophenones; Propranolol; Spironolactone; Thyroxine; Tryptophan; Valproic Acid | 1985 |
New insights into uremia-induced alterations in metabolic pathways.
Topics: Dyslipidemias; Humans; Kidney Failure, Chronic; Metabolic Networks and Pathways; Metabolome; Metabolomics; Phosphatidylcholines; Triglycerides; Tryptophan; Uremia | 2011 |
Nutrients Turned into Toxins: Microbiota Modulation of Nutrient Properties in Chronic Kidney Disease.
Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Microbiome; Humans; Methylamines; Micronutrients; Oxalates; Phosphates; Phosphatidylcholines; Renal Insufficiency, Chronic; Tryptophan; Tyrosine | 2017 |
3 trial(s) available for phosphatidylcholines and tryptophan
| Article | Year |
|---|---|
Early stages of late onset Alzheimer's disease. Diagnostic criteria, protein metabolism, precursor loading effects, neurochemical and neuropsychological applications.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Choline; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Levodopa; Male; Nerve Tissue Proteins; Neuropsychological Tests; Neurotransmitter Agents; Phosphatidylcholines; Tryptophan | 1989 |
The effects of L-tryptophan and melatonin on selected biochemical parameters in patients with steatohepatitis.
Topics: Adult; Antioxidants; Cytokines; Fatty Liver; Female; gamma-Glutamyltransferase; Hepatocytes; Humans; Insulin Resistance; Liver; Liver Cirrhosis; Liver Function Tests; Male; Melatonin; Middle Aged; Oxidative Stress; Phosphatidylcholines; Triglycerides; Tryptophan; Young Adult | 2010 |
Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease--14 months follow up.
Topics: Adult; Cholesterol, LDL; Cytokines; Fatty Liver; Female; gamma-Glutamyltransferase; Humans; Lipid Metabolism; Liver; Male; Melatonin; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Triglycerides; Tryptophan; Young Adult | 2014 |
225 other study(ies) available for phosphatidylcholines and tryptophan
| Article | Year |
|---|---|
The orientation of nisin in membranes.
Topics: Acrylamide; Acrylamides; Amino Acid Sequence; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nisin; Phosphatidylcholines; Phosphatidylglycerols; Spectrometry, Fluorescence; Spin Labels; Tryptophan | 1998 |
Peptide-induced formation of cholesterol-rich domains.
Topics: Calorimetry, Differential Scanning; Carbohydrate Sequence; Carbon Isotopes; Cholesterol; Crystallization; Lipid Bilayers; Liposomes; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Phosphatidylcholines; Protein Structure, Tertiary; Protons; Spectrometry, Fluorescence; Thermodynamics; Tryptophan | 2003 |
Binding of LL-37 to model biomembranes: insight into target vs host cell recognition.
Topics: Acrylamide; Amyloid; Antimicrobial Cationic Peptides; Cathelicidins; Circular Dichroism; Fluorescence Resonance Energy Transfer; Humans; Kinetics; Lipid Bilayers; Liposomes; Microbial Sensitivity Tests; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Spectrometry, Fluorescence; Time Factors; Tryptophan | 2008 |
Black lipid membranes as a model for intestinal absorption of drugs.
Topics: 4-Aminobenzoic Acid; Chemical Phenomena; Chemistry; Cholesterol; Eggs; Intestinal Absorption; Intestine, Small; Lipids; Membranes, Artificial; Models, Biological; Permeability; Phosphatidylcholines; Salicylamides; Salicylates; Solubility; Tryptophan | 1977 |
NMR observation of gramicidin A' in phosphatidylcholine vesicles.
Topics: Gramicidin; Kinetics; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Biological; Myristic Acids; Phosphatidylcholines; Thulium; Tryptophan; Yttrium | 1977 |
Fluorescence quenching of Ca2+-ATPase in bilayer vesicles by a spin-labeled phospholipid.
Topics: Calcium-Transporting ATPases; Cholic Acids; Membrane Fluidity; Membranes, Artificial; Phosphatidylcholines; Sarcoplasmic Reticulum; Spectrometry, Fluorescence; Spin Labels; Temperature; Tryptophan | 1978 |
Purification and properties of a lipid acyl-hydrolase from potato tubers.
Topics: Binding Sites; Galactose; Glycerides; Glycolipids; Hydrogen-Ion Concentration; Kinetics; Lipase; Molecular Weight; Phosphatidylcholines; Phospholipids; Plants; Serine; Sulfhydryl Compounds; Tryptophan; Tyrosine | 1975 |
Intestinal bacteria and cancer.
Topics: Amino Acids; Bacteria; Bile Acids and Salts; Carcinogens; Cholesterol; Colonic Neoplasms; Humans; Intestine, Large; Phosphatidylcholines; Rectal Neoplasms; Tryptophan | 1979 |
Gramicidin conformational studies with mixed-chain unsaturated phospholipid bilayer systems.
Topics: Circular Dichroism; Diphenylhexatriene; Fluorescence Polarization; Gramicidin; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Protein Conformation; Tryptophan | 1992 |
Sterol specific inactivation of gramicidin A induced membrane cation permeability.
Topics: Animals; Cell Membrane Permeability; Cholesterol; Diffusion; Electric Conductivity; Ergosterol; Erythrocyte Membrane; Gramicidin; Humans; Ion Channels; Lipid Bilayers; Phosphatidylcholines; Rubidium Radioisotopes; Tryptophan | 1992 |
pH-dependent membrane fusion and vesiculation of phospholipid large unilamellar vesicles induced by amphiphilic anionic and cationic peptides.
Topics: Amino Acid Sequence; Anions; Cations; Fluorescence; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Hydrogen-Ion Concentration; Membrane Fusion; Microscopy, Electron; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Conformation; Tryptophan | 1992 |
Average membrane penetration depth of tryptophan residues of the nicotinic acetylcholine receptor by the parallax method.
Topics: Acetylcholine; Animals; Cell Membrane; Fluorescence Polarization; Phosphatidylcholines; Phospholipids; Receptors, Nicotinic; Torpedo; Tryptophan | 1991 |
Membrane interaction of 'peptide P' derived from the repeating motif of properdin.
Topics: Amino Acid Sequence; Binding Sites; Cell Membrane; Energy Transfer; Humans; Lipid Bilayers; Microscopy, Fluorescence; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Platelet Membrane Glycoproteins; Properdin; Sulfoglycosphingolipids; Thrombospondins; Tryptophan | 1991 |
Protein kinase C penetration into lipid bilayers.
Topics: Adenosine Triphosphate; Animals; Brain; Cations, Divalent; Cytosol; Kinetics; Ligands; Lipid Bilayers; Male; Perchlorates; Phosphatidylcholines; Phosphatidylserines; Protein Conformation; Protein Kinase C; Pyridines; Rats; Rats, Inbred Strains; Tryptophan | 1990 |
Tryptophan fluorescence study on the interaction of the signal peptide of the Escherichia coli outer membrane protein PhoE with model membranes.
Topics: Amino Acid Sequence; Bacterial Outer Membrane Proteins; Cardiolipins; Escherichia coli; Fluorescence; Lipid Bilayers; Membrane Lipids; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Porins; Protein Sorting Signals; Tryptophan | 1990 |
The role of charge and hydrophobicity in peptide-lipid interaction: a comparative study based on tryptophan fluorescence measurements combined with the use of aqueous and hydrophobic quenchers.
Topics: Amino Acid Sequence; Cardiolipins; Chemical Phenomena; Chemistry, Physical; Fluorescence; Fluorescent Dyes; Lipid Bilayers; Liposomes; Membrane Lipids; Molecular Sequence Data; Peptides; Phosphatidylcholines; Solubility; Tryptophan | 1990 |
Quenching of tryptophan fluorescence by brominated phospholipid.
Topics: Amino Acid Sequence; Kinetics; Lipid Bilayers; Molecular Sequence Data; Oligopeptides; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1990 |
Interaction of fluorescent delta 5,7,9(11),22-ergostatetraen-3 beta-ol with sterol carrier protein-2.
Topics: Animals; Carrier Proteins; Cholesterol; Energy Transfer; Ergosterol; Fluorescence Polarization; Light; Liposomes; Liver; Microsomes, Liver; Phosphatidylcholines; Plant Proteins; Protein Binding; Rats; Scattering, Radiation; Sterol O-Acyltransferase; Sterols; Tryptophan | 1990 |
Effects of phospholipid on the structure of human apolipoprotein A-IV.
Topics: Apolipoproteins A; Circular Dichroism; Energy Transfer; Fluoresceins; Humans; Liposomes; Molecular Structure; Phosphatidylcholines; Phospholipids; Protein Conformation; Protein Denaturation; Spectrometry, Fluorescence; Thermodynamics; Tryptophan; Tyrosine | 1990 |
The tryptophans of gramicidin are essential for the lipid structure modulating effect of the peptide.
Topics: Amino Acid Sequence; Chemical Phenomena; Chemistry; Formates; Gramicidin; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Membrane Lipids; Phosphatidylcholines; Structure-Activity Relationship; Tryptophan | 1985 |
Phase separation and hexagonal HII phase formation by gramicidins A, B and C in dioleoylphosphatidylcholine model membranes. A study on the role of the tryptophan residues.
Topics: Gramicidin; Magnetic Resonance Spectroscopy; Membranes, Artificial; Phosphatidylcholines; Tryptophan; X-Ray Diffraction | 1987 |
Effects of ionizing radiation on artificial (planar) lipid membranes. I. Radiation inactivation of the ion channel gramicidin A.
Topics: Dose-Response Relationship, Radiation; Free Radicals; Gramicidin; Hydroxides; Ion Channels; Lipid Bilayers; Models, Biological; Phosphatidylcholines; Phosphatidylserines; Structure-Activity Relationship; Tryptophan; X-Rays | 1987 |
pH-dependent fusion of phosphatidylcholine small vesicles. Induction by a synthetic amphipathic peptide.
Topics: Amino Acid Sequence; Dextrans; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Light; Liposomes; Peptides; Phosphatidylcholines; Scattering, Radiation; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan | 1988 |
The different influences of ether and ester phospholipids on the conformation of gramicidin A. A molecular modelling study.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Carboxylic Acids; Computer Simulation; Esters; Ethers; Gramicidin; Hydrogen Bonding; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Permeability; Phosphatidylcholines; Phospholipids; Protein Conformation; Sodium; Tryptophan | 1989 |
The effects of viscosity on gramicidin tryptophan rotational motion.
Topics: Glucosides; Gramicidin; Ion Channels; Lipid Bilayers; Micelles; Models, Biological; Phosphatidylcholines; Protein Conformation; Rotation; Solvents; Spectrometry, Fluorescence; Thermodynamics; Tryptophan; Viscosity | 1988 |
Effect of micelle diameter on tryptophan dynamics in an amphipathic helical peptide in phosphatidylcholine.
Topics: Acrylamides; Amino Acid Sequence; Chemical Phenomena; Chemistry, Physical; Colloids; Dimyristoylphosphatidylcholine; Fluorescence; Micelles; Molecular Conformation; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Conformation; Temperature; Tryptophan | 1989 |
Interaction of Shigella toxin with globotriaosyl ceramide receptor-containing membranes: a fluorescence study.
Topics: Acrylamide; Acrylamides; Bacterial Toxins; Dimyristoylphosphatidylcholine; Globosides; Glycosphingolipids; Lipid Bilayers; Liposomes; Phosphatidylcholines; Protein Conformation; Shiga Toxins; Shigella dysenteriae; Spectrometry, Fluorescence; Trihexosylceramides; Tryptophan | 1989 |
Tryptophan fluorescence of mitochondrial complex III reconstituted in phosphatidylcholine bilayers.
Topics: Animals; Cattle; Electron Transport Complex III; Kinetics; Lipid Bilayers; Mitochondria, Heart; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1987 |
Neurotransmitter precursors and brain function.
Topics: Aged; Aging; Alzheimer Disease; Animals; Biological Transport; Brain; Diet; Humans; Learning; Levodopa; Memory; Neurotransmitter Agents; Parkinson Disease; Phosphatidylcholines; Serotonin; Sleep; Tryptophan | 1986 |
Binding of long-chain alkyl derivatives to lipid bilayers and to (Ca2+-Mg2+)-ATPase.
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Fatty Acids; Hydrogen-Ion Concentration; Kinetics; Lipid Bilayers; Muscles; Phosphatidylcholines; Protein Binding; Rabbits; Structure-Activity Relationship; Tryptophan | 1986 |
Preferential association of apocytochrome c with negatively charged phospholipids in mixed model membranes.
Topics: Apoproteins; Biological Transport; Cytochrome c Group; Cytochromes c; Electron Spin Resonance Spectroscopy; Energy Transfer; In Vitro Techniques; Membrane Fluidity; Membrane Lipids; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Phospholipids; Spectrometry, Fluorescence; Tryptophan | 1986 |
Preferential lipid association and mode of penetration of apocytochrome c in mixed model membranes as monitored by tryptophanyl fluorescence quenching using brominated phospholipids.
Topics: Apoproteins; Bromine; Cytochrome c Group; Cytochromes c; Membranes, Artificial; Phosphatidylcholines; Phosphatidylserines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1987 |
[Oxidation of the indole ring induced by the auto-oxidation of unsaturated lipids. Application to tryptophan residues of high and low density lipoproteins of human serum].
Topics: Arachidonic Acids; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Liposomes; Oxidation-Reduction; Phosphatidylcholines; Tryptophan | 1988 |
Site-site interaction in the phospholipid activation of D-beta-hydroxybutyrate dehydrogenase.
Topics: Binding Sites; Enzyme Activation; Hydroxybutyrate Dehydrogenase; Kinetics; Mathematics; Phosphatidylcholines; Spectrometry, Fluorescence; Tryptophan | 1986 |
Lipid specific penetration of melittin into phospholipid model membranes.
Topics: Amino Acids; Animals; Anions; Anthracenes; Bee Venoms; Cattle; Chromatography; Chromatography, High Pressure Liquid; Energy Transfer; Fluorescence; Liposomes; Melitten; Membrane Lipids; Myocardium; Nitrates; Phosphatidylcholines; Phospholipases A; Phospholipids; Spectrometry, Fluorescence; Stearic Acids; Tryptophan | 1987 |
Depth-dependent fluorescent quenching of a tryptophan residue located at defined positions on a rigid 21-peptide helix in liposomes.
Topics: Alamethicin; Circular Dichroism; Indicators and Reagents; Liposomes; Models, Biological; Peptides; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan | 1987 |
Correlations between structure and spectroscopic properties in membrane model systems. Tryptophan and I-anilino-8-naphthalene sulfonate fluorescence in protein-lipid-water phases.
Topics: Fluorescence; Membranes, Artificial; Models, Structural; Muramidase; Naphthalenes; Phosphatidylcholines; Phosphatidylinositols; Phospholipids; Spectrophotometry; Sulfonic Acids; Tryptophan; X-Ray Diffraction | 1970 |
Polypeptide hormone interaction. II. Glucagon binding to lysolecithin.
Topics: Adrenocorticotropic Hormone; Aniline Compounds; Animals; Calcitonin; Cattle; Colloids; Fluorescent Dyes; Glucagon; Hydrogen-Ion Concentration; Kinetics; Lysophosphatidylcholines; Macromolecular Substances; Naphthalenes; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Spectrometry, Fluorescence; Sulfonic Acids; Swine; Tryptophan | 1972 |
Interaction of apolipoprotein-alamine and apolipoprotein-glutamine-I with phosphatidylcholine. Effect on solute quenching of intrinsic fluorescence.
Topics: Alanine; Apoproteins; Chlorine; Eggs; Glutamine; Humans; Iodides; Lipoproteins; Lipoproteins, HDL; Lipoproteins, VLDL; Phosphatidylcholines; Protein Binding; Pyridinium Compounds; Serum Albumin; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan | 1974 |
Carriers and specificity in membranes. V. Neuron membranes. Membrane phenomena at the synapse.
Topics: Absorption; Acetylcholine; Aminobutyrates; Biological Transport; Biological Transport, Active; Cell Membrane Permeability; Choline; Norepinephrine; Phosphatidylcholines; Potassium; Sodium; Synapses; Synaptic Transmission; Synaptosomes; Tryptophan | 1971 |
Structure of the major complex formed by interaction of phosphatidylcholine bilamellar vesicles and apolipoprotein-alanine (APO-C-III).
Topics: Alanine; Apoproteins; Binding Sites; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Circular Dichroism; Humans; Light; Lipoproteins, VLDL; Mathematics; Membranes, Artificial; Microscopy, Electron; Molecular Conformation; Phosphatidylcholines; Protein Binding; Protein Conformation; Scattering, Radiation; Spectrometry, Fluorescence; Tryptophan; Ultracentrifugation; Ultrafiltration | 1974 |
[Incorporation of auxin into swollen lecithin lamellae].
Topics: Arachidonic Acids; Benzoates; Carbon Isotopes; Carbon Tetrachloride; Chemical Phenomena; Chemistry; Cholesterol; Glycerol; Glycolates; Herbicides; Indoleacetic Acids; Oleic Acids; Phenylacetates; Phosphatidylcholines; Plant Growth Regulators; Solutions; Stearic Acids; Tryptophan; Valerates | 1969 |
The enzymatic synthesis of L-tryptophan analogues.
Topics: Alcohols; Aza Compounds; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Escherichia coli; Fluorine; Indoles; Isotope Labeling; Methyl Ethers; Phosphatidylcholines; Pyrimidines; Serine; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Tryptophan Synthase | 1974 |
Zymogen-enzyme transformations. On the mechanism of activation of prophospholipase A.
Topics: Alanine; Aminopeptidases; Animals; Binding Sites; Calcium; Enzyme Activation; Enzyme Precursors; Kinetics; Optical Rotatory Dispersion; Pancreas; Phosphatidylcholines; Phospholipases; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Swine; Trypsin; Tryptophan | 1972 |
Spectral perturbations of Crotalus adamanteus phospholipase A 2 induced by divalent cation binding.
Topics: Animals; Barium; Binding Sites; Cadmium; Calcium; Caproates; Cations, Divalent; Dialysis; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Nitrobenzenes; Phosphatidylcholines; Phospholipases; Protein Binding; Protein Conformation; Snakes; Spectrophotometry, Ultraviolet; Strontium; Tryptophan; Zinc | 1973 |
Isolation and characterization of two phospholipase A's from the venom of Agkistrodon lays blomhoffii.
Topics: Animals; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Circular Dichroism; Diffusion; Drug Stability; Electrophoresis, Disc; Hexosamines; Hexoses; Hydrogen-Ion Concentration; Isoelectric Focusing; Methods; Molecular Weight; Neuraminic Acids; Nitrogen; Optical Rotatory Dispersion; Phosphatidylcholines; Phospholipases; Snakes; Spectrophotometry; Sulfhydryl Compounds; Sulfur; Tryptophan; Tyrosine; Ultracentrifugation; Ultraviolet Rays; Venoms; Viscosity | 1971 |
Precursor control of neurotransmitter synthesis.
Topics: Behavior; Choline; Feedback; Humans; Nervous System Diseases; Neurons; Neurotransmitter Agents; Phosphatidylcholines; Synapses; Synaptic Transmission; Tryptophan; Tyrosine | 1980 |
Nutrients that modify brain function.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain; Chemical Phenomena; Chemistry; Choline; Diet; Humans; Memory; Neurotransmitter Agents; Phosphatidylcholines; Rodentia; Serotonin; Tryptophan; Tyrosine | 1982 |
Static and time-resolved fluorescence studies of fluorescent phosphatidylcholine bound to the phosphatidylcholine transfer protein of bovine liver.
Topics: Androgen-Binding Protein; Binding Sites; Carrier Proteins; Kinetics; Phosphatidylcholines; Phospholipid Transfer Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan | 1984 |
Dissociation of apolipoprotein AI from apoprotein-lipid complexes and from high-density lipoproteins. A fluorescence study.
Topics: Apolipoprotein A-I; Apolipoproteins; Dimyristoylphosphatidylcholine; Guanidine; Guanidines; Humans; Kinetics; Lipoproteins, LDL; Phosphatidylcholines; Protein Denaturation; Spectrometry, Fluorescence; Tryptophan | 1982 |
Melittin-phospholipid interaction studied by employing the single tryptophan residue as an intrinsic fluorescent probe.
Topics: Bee Venoms; Binding Sites; Kinetics; Melitten; Phosphatidylcholines; Protein Binding; Spectrometry, Fluorescence; Structure-Activity Relationship; Time Factors; Tryptophan | 1982 |
Interactions between tryptophan and multilamellar liposomes. Effect of n-butanol on tryptophan fluorescence.
Topics: 1-Butanol; Butanols; Liposomes; Phosphatidylcholines; Spectrometry, Fluorescence; Temperature; Tryptophan | 1982 |
Motionally restricted tryptophan environments at the peptide-lipid interface of gramicidin channels.
Topics: Gramicidin; Ion Channels; Lipid Bilayers; Mathematics; Models, Structural; Models, Theoretical; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1994 |
Mechanism of interaction of protein kinase C with phorbol esters. Reversibility and nature of membrane association.
Topics: Calcium; Diglycerides; Kinetics; Liposomes; Membrane Fluidity; Osmolar Concentration; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylcholines; Protein Binding; Protein Kinase C; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Tryptophan | 1995 |
The binding of natural and fluorescent lysophospholipids to wild-type and mutant rat liver fatty acid-binding protein and albumin.
Topics: Albumins; Animals; Binding Sites; Carrier Proteins; Dansyl Compounds; Energy Transfer; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Fluorescence Polarization; Fluorescent Dyes; Fluorometry; Hydrogen Bonding; Kinetics; Liver; Lysophospholipids; Mutagenesis, Site-Directed; Neoplasm Proteins; Nerve Tissue Proteins; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Rats; Recombinant Fusion Proteins; Tryptophan | 1995 |
Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: change in the aromatic side chains upon binding and insertion.
Topics: Bacterial Toxins; Circular Dichroism; Clostridium perfringens; Erythrocyte Membrane; Hemolysin Proteins; In Vitro Techniques; Liposomes; Membranes, Artificial; Phosphatidylcholines; Protein Structure, Secondary; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan | 1995 |
Ricin-membrane interaction: membrane penetration depth by fluorescence quenching and resonance energy transfer.
Topics: Circular Dichroism; Cyclic N-Oxides; Dithiothreitol; Electron Spin Resonance Spectroscopy; Energy Transfer; Fluorescent Dyes; HEPES; Hydrogen-Ion Concentration; Kinetics; Lipid Bilayers; Liposomes; Models, Biological; Naphthalenesulfonates; Phosphatidylcholines; Protein Conformation; Ricin; Spectrometry, Fluorescence; Spin Labels; Sulfhydryl Reagents; Tryptophan | 1994 |
Characterization of the single Ca(2+)-binding site on the Ca(2+)-ATPase reconstituted with short- or long-chain phosphatidylcholines.
Topics: Binding Sites; Calcium; Calcium-Transporting ATPases; Coumarins; Fluorescent Dyes; Magnesium; Muscle, Skeletal; Oxadiazoles; Phosphatidylcholines; Protein Conformation; Sarcoplasmic Reticulum; Spectrometry, Fluorescence; Tryptophan | 1994 |
Distribution of distances between the tryptophan and the N-terminal residue of melittin in its complex with calmodulin, troponin C, and phospholipids.
Topics: Calmodulin; Chemical Phenomena; Chemistry, Physical; Dansyl Compounds; Liposomes; Melitten; Phosphatidylcholines; Phospholipids; Spectrophotometry; Troponin; Troponin C; Tryptophan | 1994 |
Phosphatidylinositol-specific phospholipase C from Bacillus cereus at the lipid-water interface: interfacial binding, catalysis, and activation.
Topics: Bacillus cereus; Binding Sites; Binding, Competitive; Catalysis; Enzyme Activation; Glycerophospholipids; Kinetics; Lipid Bilayers; Liposomes; Micelles; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phospholipids; Phosphoric Diester Hydrolases; Spectrometry, Fluorescence; Tryptophan; Water | 1994 |
Pyrularia thionin binding to and the role of tryptophan-8 in the enhancement of phosphatidylserine domains in erythrocyte membranes.
Topics: Animals; Antimicrobial Cationic Peptides; Cytotoxins; Erythrocyte Membrane; Image Processing, Computer-Assisted; In Vitro Techniques; Membrane Fluidity; Membrane Lipids; Microscopy, Fluorescence; Phosphatidylcholines; Phosphatidylserines; Plant Proteins; Plants, Toxic; Rabbits; Tryptophan | 1993 |
Colicin Ia inserts into negatively charged membranes at low pH with a tertiary but little secondary structural change.
Topics: Chromatography, Gel; Chromatography, Ion Exchange; Circular Dichroism; Colicins; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Liposomes; Phosphatidylcholines; Plasmids; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan | 1993 |
Kinetics of the interaction of amphipathic alpha-helical peptides with phosphatidylcholines.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Dimyristoylphosphatidylcholine; Energy Transfer; Fluorescent Dyes; Kinetics; Lipid Bilayers; Liposomes; Molecular Sequence Data; Peptides; Phosphatidylcholines; Tryptophan | 1993 |
Relationship between annexin V tryptophan exposure, calcium, and phospholipid binding.
Topics: Annexin A5; Calcium; Humans; Liposomes; Micelles; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Recombinant Proteins; Spectrometry, Fluorescence; Spermine; Tryptophan | 1993 |
Induction of nonbilayer structures in diacylphosphatidylcholine model membranes by transmembrane alpha-helical peptides: importance of hydrophobic mismatch and proposed role of tryptophans.
Topics: Amino Acid Sequence; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Lipids; Membrane Proteins; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Temperature; Tryptophan | 1996 |
Membrane-protein interaction and the molten globule state: interaction of alpha-lactalbumin with membranes.
Topics: Acrylamides; Animals; Apoproteins; Cattle; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Iodides; Lactalbumin; Lipid Bilayers; Liposomes; Phosphatidylcholines; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tryptophan | 1995 |
Conformation, stability and interactions of corneal keratan sulfate proteoglycan.
Topics: Animals; Cattle; Cesium; Chondroitin Sulfate Proteoglycans; Circular Dichroism; Collagen; Cornea; Guanidine; Guanidines; Hydrogen-Ion Concentration; Keratan Sulfate; Liposomes; Lumican; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Temperature; Tryptophan | 1996 |
Truncations of the C-terminus have different effects on the conformation and activity of phosphatidylinositol transfer protein.
Topics: Acrylamide; Acrylamides; Anilino Naphthalenesulfonates; Animals; Carrier Proteins; Circular Dichroism; Cysteine; Dithionitrobenzoic Acid; Escherichia coli; Kinetics; Membrane Proteins; Mutation; Phosphatidylcholines; Phosphatidylinositols; Phospholipid Transfer Proteins; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Rats; Recombinant Proteins; Sequence Deletion; Tryptophan | 1996 |
Folding intermediates of a beta-barrel membrane protein. Kinetic evidence for a multi-step membrane insertion mechanism.
Topics: Bacterial Outer Membrane Proteins; Dimyristoylphosphatidylcholine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Lipid Bilayers; Models, Molecular; Molecular Weight; Phosphatidylcholines; Protein Conformation; Protein Folding; Protein Structure, Secondary; Spectrometry, Fluorescence; Temperature; Tryptophan | 1996 |
Design and synthesis of amphiphilic alpha-helical model peptides with systematically varied hydrophobic-hydrophilic balance and their interaction with lipid- and bio-membranes.
Topics: Amino Acid Sequence; Bacteria; Cell Membrane; Chromatography, High Pressure Liquid; Circular Dichroism; Fungi; Hemolysis; Leucine; Lipid Metabolism; Liposomes; Lysine; Molecular Sequence Data; Nephelometry and Turbidimetry; Peptides; Permeability; Phosphatidylcholines; Protein Structure, Secondary; Spectrometry, Fluorescence; Structure-Activity Relationship; Surface-Active Agents; Tryptophan | 1996 |
New fluorescent octadecapentaenoic acids as probes of lipid membranes and protein-lipid interactions.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Blood Platelets; Calorimetry; Cell Membrane; Dimyristoylphosphatidylcholine; Energy Transfer; Fatty Acids, Unsaturated; Fluorescence Polarization; Fluorescent Dyes; Gels; Gramicidin; Humans; Isomerism; Kinetics; Lipid Bilayers; Liposomes; Molecular Conformation; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Proteins; Spectrometry, Fluorescence; Tryptophan; Ultrasonography | 1996 |
The structure and organization of synthetic putative membranous segments of ROMK1 channel in phospholipid membranes.
Topics: 4-Chloro-7-nitrobenzofurazan; Calorimetry; Cholesterol; Circular Dichroism; Energy Transfer; Kinetics; Liposomes; Peptide Fragments; Phosphatidylcholines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Structure, Secondary; Spectrometry, Fluorescence; Thermodynamics; Trifluoroethanol; Tryptophan; Water | 1997 |
Bilayer interactions of indolicidin, a small antimicrobial peptide rich in tryptophan, proline, and basic amino acids.
Topics: Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; Circular Dichroism; Kinetics; Lipid Bilayers; Liposomes; Naphthalenes; Octoxynol; Peptides; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Pyridinium Compounds; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan | 1997 |
Fluorescence studies on the interaction of a synthetic signal peptide and its analog with liposomes.
Topics: Acrylamide; Acrylamides; Amino Acid Sequence; Chymotrypsin; Dithionite; Escherichia coli; Liposomes; Membrane Potentials; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylserines; Phosphoenolpyruvate Sugar Phosphotransferase System; Protein Sorting Signals; Sodium Iodide; Spectrometry, Fluorescence; Tryptophan | 1997 |
Conformations and orientations of aromatic amino acid residues of tachyplesin I in phospholipid membranes.
Topics: Amino Acid Sequence; Amino Acids; Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; Circular Dichroism; DNA-Binding Proteins; Fluorescence Polarization; Horseshoe Crabs; Kinetics; Liposomes; Models, Molecular; Molecular Sequence Data; Peptides, Cyclic; Phenylalanine; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1997 |
Conformational adaptation of annexin V upon binding to liposomes: a time-resolved fluorescence study.
Topics: Annexin A5; Calcium; Humans; Liposomes; Phosphatidylcholines; Placenta; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1997 |
Effect of the N-terminal glycine on the secondary structure, orientation, and interaction of the influenza hemagglutinin fusion peptide with lipid bilayers.
Topics: Amino Acid Sequence; Circular Dichroism; Dimyristoylphosphatidylcholine; Glycine; Hemagglutinin Glycoproteins, Influenza Virus; Influenza A virus; Lipid Bilayers; Membrane Fusion; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan | 1996 |
Incorporation of melittin into phosphatidylcholine bilayers. Study of binding and conformational changes.
Topics: Circular Dichroism; Fatty Acids; Fluorescence; Lipid Bilayers; Macromolecular Substances; Melitten; Nitrates; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Sodium Chloride; Solutions; Spectrometry, Fluorescence; Spin Labels; Tryptophan | 1981 |
Ionization, partitioning, and dynamics of tryptophan octyl ester: implications for membrane-bound tryptophan residues.
Topics: Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Liposomes; Membrane Proteins; Models, Chemical; Phosphatidylcholines; Spectrometry, Fluorescence; Tryptophan | 1997 |
Effect of n-alkanols on lipid bilayer hydration.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Alcohols; Dansyl Compounds; Fluorescence Polarization; Fluorescent Dyes; Gramicidin; Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Spectrometry, Fluorescence; Tryptophan; Water | 1997 |
Interaction of the delta-endotoxin CytA from Bacillus thuringiensis var. israelensis with lipid membranes.
Topics: Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Binding Sites; Calorimetry, Differential Scanning; Circular Dichroism; Endotoxins; Hemolysin Proteins; Kinetics; Liposomes; Phosphatidylcholines; Protein Conformation; Spectroscopy, Fourier Transform Infrared; Spin Labels; Thermodynamics; Tryptophan | 1997 |
Interaction of class A amphipathic helical peptides with phospholipid unilamellar vesicles.
Topics: Calorimetry; Circular Dichroism; Lipid Bilayers; Liposomes; Peptides; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Spectrometry, Fluorescence; Temperature; Thermodynamics; Tryptophan | 1997 |
Modulation of tryptophan environment in membrane-bound melittin by negatively charged phospholipids: implications in membrane organization and function.
Topics: Animals; Bees; Circular Dichroism; Dimyristoylphosphatidylcholine; Kinetics; Lipid Bilayers; Melitten; Models, Molecular; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Protein Conformation; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan | 1997 |
Tertiary structural changes of the alpha-hemolysin from Staphylococcus aureus on association with liposome membranes.
Topics: Bacterial Toxins; Cholesterol; Chromatography, Ion Exchange; Circular Dichroism; Fluorescence; Hemolysin Proteins; Hydrogen-Ion Concentration; Liposomes; Macromolecular Substances; Phosphatidylcholines; Protein Conformation; Protein Structure, Tertiary; Spectrometry, Fluorescence; Staphylococcus aureus; Tryptophan | 1998 |
Conformation of apolipoprotein AI in reconstituted lipoprotein particles and particle-membrane interaction: effect of cholesterol.
Topics: Antibodies, Monoclonal; Apolipoprotein A-I; Binding, Competitive; Cholesterol; Epitopes; Fluorescence; Guanidine; Lipoproteins, HDL; Liposomes; Particle Size; Permeability; Phosphatidylcholines; Picolinic Acids; Protein Conformation; Protein Denaturation; Terbium; Tryptophan | 1998 |
Spectroscopic analysis of halothane binding to the plasma membrane Ca2+-ATPase.
Topics: Acrylamide; Acrylamides; Anesthetics, Inhalation; Binding Sites; Calcium-Transporting ATPases; Ethers; Halothane; Kinetics; Phosphatidylcholines; Protein Conformation; Protein Denaturation; Spectrometry, Fluorescence; Tryptophan; Urea | 1998 |
Interaction and orientation of an alpha-aminoisobutyric acid- and tryptophan-containing short helical peptide pore-former in phospholipid vesicles, as revealed by fluorescence spectroscopy.
Topics: Gramicidin; Lipid Bilayers; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Structure, Secondary; Spectrometry, Fluorescence; Structure-Activity Relationship; Time Factors; Tryptophan | 1998 |
Folding of beta-sheet membrane proteins: a hydrophobic hexapeptide model.
Topics: Circular Dichroism; Fluorescence; Kinetics; Lipid Bilayers; Liposomes; Membrane Proteins; Peptides; Permeability; Phosphatidylcholines; Protein Folding; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Temperature; Thermodynamics; Tryptophan | 1998 |
Structural investigations of basic amphipathic model peptides in the presence of lipid vesicles studied by circular dichroism, fluorescence, monolayer and modeling.
Topics: Amino Acid Sequence; Anions; Cations; Circular Dichroism; Liposomes; Membrane Potentials; Membranes, Artificial; Models, Chemical; Models, Molecular; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Binding; Spectrometry, Fluorescence; Surface-Active Agents; Thermodynamics; Tryptophan | 1998 |
Depth profiles of pulmonary surfactant protein B in phosphatidylcholine bilayers, studied by fluorescence and electron spin resonance spectroscopy.
Topics: Animals; Electron Spin Resonance Spectroscopy; Energy Transfer; Lipid Bilayers; Phosphatidylcholines; Protein Binding; Proteolipids; Pulmonary Alveoli; Pulmonary Surfactants; Spectrometry, Fluorescence; Swine; Tryptophan | 1998 |
Calcium-triggered selective intermembrane exchange of phospholipids by the lung surfactant protein SP-A.
Topics: Calcium; Calcium Chloride; Cell Membrane; Dose-Response Relationship, Drug; Fluorescence Polarization; Fluorescent Dyes; Humans; Liposomes; Lung; Membrane Lipids; Phosphatidylcholines; Phosphatidylethanolamines; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Pyrenes; Sphingomyelins; Tryptophan; Water | 1998 |
Tryptophan-containing mutant of human (group IIa) secreted phospholipase A2 has a dramatically increased ability to hydrolyze phosphatidylcholine vesicles and cell membranes.
Topics: 3T3 Cells; Animals; Cell Membrane; Group II Phospholipases A2; Humans; Hydrolysis; Membrane Lipids; Mice; Microsomes, Liver; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Protein Binding; Rats; Rats, Wistar; Recombinant Proteins; Swine; Tryptophan; Valine | 1998 |
Insight into the environment of tryptophan in a hydrophobic model peptide upon aggregation and interaction with lipid vesicles: a steady state and time resolved fluorescence study.
Topics: Amino Acid Sequence; Binding Sites; Lipid Bilayers; Oligopeptides; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1998 |
Environment- and sequence-dependent modulation of the double-stranded to single-stranded conformational transition of gramicidin A in membranes.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cholestenes; Chromatography, High Pressure Liquid; Circular Dichroism; Dimerization; Enterococcus faecium; Fatty Acids, Unsaturated; Gramicidin; Lipid Bilayers; Microbial Sensitivity Tests; Molecular Sequence Data; Phenylalanine; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1998 |
Picosecond tryptophan fluorescence of membrane-bound prothrombin fragment 1.
Topics: Animals; Calcium; Cattle; Membranes, Artificial; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Protein Precursors; Prothrombin; Spectrometry, Fluorescence; Tryptophan | 1998 |
The preference of tryptophan for membrane interfaces.
Topics: Bacterial Outer Membrane Proteins; Lipid Bilayers; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Porins; Receptors, Virus; Static Electricity; Surface Properties; Thermodynamics; Tryptophan; Water | 1998 |
Interaction of the wheat endosperm lipid-binding protein puroindoline-a with phospholipids.
Topics: Amino Acid Sequence; Binding Sites; Lipid Bilayers; Lysophosphatidylcholines; Micelles; Molecular Sequence Data; Osmolar Concentration; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Plant Proteins; Protein Conformation; Seeds; Solubility; Spectrometry, Fluorescence; Static Electricity; Temperature; Triticum; Trypsin; Tryptophan | 1998 |
Membrane topography of the T domain of diphtheria toxin probed with single tryptophan mutants.
Topics: Dimyristoylphosphatidylcholine; Diphtheria Toxin; Fluorescence Polarization; Hydrogen-Ion Concentration; Membrane Proteins; Membranes, Artificial; Models, Chemical; Mutagenesis, Site-Directed; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Solutions; Spectrometry, Fluorescence; Tryptophan | 1998 |
Localization and environment of tryptophans in soluble and membrane-bound states of a pore-forming toxin from Staphylococcus aureus.
Topics: Bacterial Toxins; Biophysical Phenomena; Biophysics; Bromosuccinimide; Cyclic N-Oxides; Hemolysin Proteins; Iodides; Membranes; Phosphatidylcholines; Protein Conformation; Solubility; Spectrometry, Fluorescence; Spin Labels; Staphylococcus aureus; Stearic Acids; Tryptophan; Water | 1999 |
Conformational basis of the phospholipid requirement for the activity of SR Ca(2+)-ATPase.
Topics: Animals; Binding Sites; Calcium-Transporting ATPases; Fluorescein-5-isothiocyanate; Fluorescent Dyes; In Vitro Techniques; Naphthalenesulfonates; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Conformation; Proteolipids; Rabbits; Sarcoplasmic Reticulum; Tryptophan | 1998 |
Probing the role of C-1 ester group in Naja naja phospholipase A2-phospholipid interactions using butanetriol-containing phosphatidylcholine analogues.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Butanols; Elapidae; Fluorescence; Hydrolysis; Kinetics; Molecular Conformation; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phospholipids; Protein Binding; Snake Venoms; Tryptophan | 1999 |
Conformational flexibility of domain III of annexin V at membrane/water interfaces.
Topics: Annexin A5; Circular Dichroism; Fluorescence Polarization; Humans; Liposomes; Membrane Lipids; Micelles; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Time Factors; Tryptophan; Water | 1999 |
Orientation of LamB signal peptides in bilayers: influence of lipid probes on peptide binding and interpretation of fluorescence quenching data.
Topics: Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Escherichia coli; Escherichia coli Proteins; Fluorescent Dyes; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Protein Binding; Protein Conformation; Protein Sorting Signals; Spectrometry, Fluorescence; Tryptophan; Valine | 1999 |
The interaction of bioactive peptides with an immobilized phosphatidylcholine monolayer.
Topics: Amino Acid Sequence; beta-Endorphin; Binding Sites; Bombesin; Dipeptides; Glucagon; Kinetics; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Silicon Dioxide; Solvents; Temperature; Thermodynamics; Tryptophan | 1999 |
Kinetic description of structural changes linked to membrane import of the colicin E1 channel protein.
Topics: Biological Transport; Cell Membrane; Circular Dichroism; Colicins; Cysteine; Energy Transfer; Ion Channels; Kinetics; Lipid Bilayers; Models, Chemical; Naphthalenesulfonates; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Protein Precursors; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan | 1999 |
Effect of lipid unsaturation on the binding of native and a mutant form of cytochrome b5 to membranes.
Topics: Bromine; Chromatography, Gel; Cytochromes b5; Escherichia coli; Fluorescent Dyes; Lipid Bilayers; Membrane Proteins; Mutagenesis, Site-Directed; Osmolar Concentration; Phosphatidylcholines; Protein Binding; Spectrometry, Fluorescence; Tryptophan | 1999 |
Evaluation of lipid exposure of tryptophan residues in membrane peptides and proteins.
Topics: Bacterial Outer Membrane Proteins; Cytochromes b5; Fluorescent Dyes; In Vitro Techniques; Kinetics; Membrane Lipids; Membrane Proteins; Models, Chemical; Peptides; Phosphatidylcholines; Protein Folding; Spectrometry, Fluorescence; Tryptophan | 1999 |
Neighboring aliphatic/aromatic side chain interactions between residues 9 and 10 in gramicidin channels.
Topics: Amino Acid Sequence; Amino Acid Substitution; Chromatography, Gel; Circular Dichroism; Deuterium; Gramicidin; Ion Channels; Leucine; Lipid Bilayers; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Conformation; Tryptophan | 2000 |
The orientation of helix 4 in apolipoprotein A-I-containing reconstituted high density lipoproteins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Apolipoprotein A-I; Apolipoproteins A; Humans; Lipid Bilayers; Lipoproteins, HDL; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylcholines; Protein Precursors; Protein Structure, Secondary; Sphingomyelins; Tryptophan | 2000 |
Designing transmembrane alpha-helices that insert spontaneously.
Topics: Amino Acid Sequence; Buffers; Circular Dichroism; Coumarins; Energy Transfer; Fluorescence; Hydrogen Bonding; Lipid Bilayers; Liposomes; Lysophospholipids; Membrane Fusion; Membrane Lipids; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Binding; Protein Engineering; Protein Structure, Secondary; Solubility; Spectrometry, Fluorescence; Thermodynamics; Tryptophan; Water | 2000 |
Cyclization of a cytolytic amphipathic alpha-helical peptide and its diastereomer: effect on structure, interaction with model membranes, and biological function.
Topics: Anti-Bacterial Agents; Electrophoresis, Polyacrylamide Gel; Growth Inhibitors; Hemolysis; Humans; Liposomes; Microbial Sensitivity Tests; Peptides, Cyclic; Permeability; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Binding; Protein Structure, Secondary; Solutions; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Structure-Activity Relationship; Tryptophan | 2000 |
Site-specific tryptophan dynamics in class A amphipathic helical peptides at a phospholipid bilayer interface.
Topics: Amino Acid Sequence; Fluorescence Polarization; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Proteins; Structure-Activity Relationship; Tryptophan; X-Ray Diffraction | 2000 |
Cholesterol efflux to high-density lipoproteins and apolipoprotein A-I phosphatidylcholine complexes is inhibited by ethanol: role of apolipoprotein structure and cooperative interaction of phosphatidylcholine and cholesterol.
Topics: Alcohol Drinking; Alcoholism; Animals; Apolipoprotein A-I; Biological Transport, Active; Cardiovascular Diseases; Cholesterol; Clone Cells; Ergosterol; Ethanol; Fluorescence Polarization; Humans; Lipoproteins, HDL; Phosphatidylcholines; Rats; Tryptophan | 2000 |
(R)-3-hydroxybutyrate dehydrogenase: selective phosphatidylcholine binding by the C-terminal domain.
Topics: Fluorescent Dyes; Glutathione Transferase; Histidine; Humans; Hydrolysis; Hydroxybutyrate Dehydrogenase; Lipid Bilayers; Myocardium; Peptide Fragments; Phosphatidylcholines; Protein Binding; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Thrombin; Tryptophan | 2000 |
Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation.
Topics: Alanine; Amides; Amino Acid Sequence; Leucine; Lipid Bilayers; Lysine; Membrane Proteins; Models, Chemical; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Tryptophan | 2001 |
A novel linear amphipathic beta-sheet cationic antimicrobial peptide with enhanced selectivity for bacterial lipids.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Bacteria; Calorimetry, Differential Scanning; Circular Dichroism; Fluoresceins; Hemolysis; Lipid Metabolism; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Structure, Secondary; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Tryptophan | 2001 |
Dynamics and orientation of amphipathic peptides in solution and bound to membranes: a steady-state and time-resolved fluorescence study of staphylococcal delta-toxin and its synthetic analogues.
Topics: Amino Acid Sequence; Amino Acid Substitution; Bacterial Toxins; Binding Sites; Cell Membrane; Dimyristoylphosphatidylcholine; Kinetics; Light; Lipid Bilayers; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylserines; Scattering, Radiation; Solutions; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan | 2001 |
Membrane-anchoring interactions of M13 major coat protein.
Topics: Amino Acid Sequence; Bacteriophage M13; Capsid; Capsid Proteins; Cysteine; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Lipid Bilayers; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Naphthalenesulfonates; Phosphatidylcholines; Spin Labels; Tryptophan | 2001 |
Exendin-4 and glucagon-like-peptide-1: NMR structural comparisons in the solution and micelle-associated states.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glycine; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutation; Peptide Fragments; Peptides; Phosphatidylcholines; Protein Precursors; Protein Structure, Secondary; Sequence Homology, Amino Acid; Stereoisomerism; Trifluoroethanol; Tryptophan; Venoms | 2001 |
Interaction of the alpha-helices of apolipophorin III with the phospholipid acyl chains in discoidal lipoprotein particles: a fluorescence quenching study.
Topics: Amino Acid Sequence; Animals; Apolipoproteins; Bromosuccinimide; Carrier Proteins; Grasshoppers; Lipid Bilayers; Lipoproteins; Molecular Sequence Data; Mutation; Phosphatidylcholines; Phospholipids; Protein Binding; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan | 2001 |
Role of the interfacial binding domain in the oxidative susceptibility of lecithin:cholesterol acyltransferase.
Topics: Animals; Binding Sites; CHO Cells; Cholesterol; Cricetinae; Cysteine; Esterification; Humans; Mutagenesis, Site-Directed; Oxidation-Reduction; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Protein Binding; Tryptophan | 2002 |
Differential destabilization of membranes by tryptophan and phenylalanine during freezing: the roles of lipid composition and membrane fusion.
Topics: Daunorubicin; Diglycerides; Freezing; Galactolipids; Glycolipids; Intracellular Membranes; Liposomes; Membrane Fusion; Membrane Lipids; Permeability; Phenylalanine; Phosphatidylcholines; Thylakoids; Tryptophan | 2002 |
Binding of the antimicrobial peptide temporin L to liposomes assessed by Trp fluorescence.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Circular Dichroism; Liposomes; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Binding; Proteins; Spectrometry, Fluorescence; Tryptophan | 2002 |
Roles of peptide-peptide charge interaction and lipid phase separation in helix-helix association in lipid bilayer.
Topics: Amino Acid Sequence; Cholesterol; Circular Dichroism; Drug Design; Electrochemistry; Energy Transfer; In Vitro Techniques; Lipid Bilayers; Liposomes; Microscopy, Electron; Models, Molecular; Oligopeptides; Phosphatidylcholines; Protein Binding; Protein Prenylation; Protein Structure, Secondary; Spectrometry, Fluorescence; Sphingomyelins; Tryptophan | 2002 |
Geometry and intrinsic tilt of a tryptophan-anchored transmembrane alpha-helix determined by (2)H NMR.
Topics: Alanine; Biophysical Phenomena; Biophysics; Cell Membrane; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Models, Theoretical; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Tryptophan | 2002 |
Mechanism and kinetics of delta-lysin interaction with phospholipid vesicles.
Topics: Amino Acid Sequence; Bacterial Proteins; Coumarins; Energy Transfer; Fluoresceins; Hemolysin Proteins; Kinetics; Lipid Bilayers; Models, Chemical; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Phospholipids; Solutions; Spectrometry, Fluorescence; Staphylococcus aureus; Tryptophan; Water | 2002 |
Phospholipid flop induced by transmembrane peptides in model membranes is modulated by lipid composition.
Topics: 4-Chloro-7-nitrobenzofurazan; Biological Transport; Cholesterol; Escherichia coli; Kinetics; Lipid Bilayers; Lipids; Lysine; Membrane Proteins; Models, Biological; Oxadiazoles; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphatidylserines; Phospholipids; Protein Structure, Secondary; Tryptophan | 2003 |
Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions.
Topics: Alanine; Circular Dichroism; Leucine; Lipid Bilayers; Lysine; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Chemical; Peptide Fragments; Phosphatidylcholines; Protein Structure, Secondary; Tryptophan | 2003 |
Effect of tryptophan insertions on the properties of the human group IIA phospholipase A2: mutagenesis produces an enzyme with characteristics similar to those of the human group V phospholipase A2.
Topics: Animals; Catalysis; Cell Membrane; Cells, Cultured; Circular Dichroism; Elapidae; Group II Phospholipases A2; Group V Phospholipases A2; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Protein Binding; Rats; Spectrometry, Fluorescence; Tryptophan | 2003 |
Molecular dynamics simulations of pentapeptides at interfaces: salt bridge and cation-pi interactions.
Topics: Arginine; Cations; Computer Simulation; Cyclohexanes; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Lysine; Models, Molecular; Molecular Mimicry; Octanols; Oligopeptides; Phosphatidylcholines; Protein Conformation; Salts; Surface Properties; Thermodynamics; Tryptophan; Water | 2003 |
Influence of tryptophan on lipid binding of linear amphipathic cationic antimicrobial peptides.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacteria; Circular Dichroism; Erythrocytes; Fluoresceins; Hemolysis; Humans; Molecular Sequence Data; Nitrophenylgalactosides; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Spectrometry, Fluorescence; Surface Plasmon Resonance; Tryptophan | 2003 |
The effect of interactions involving ionizable residues flanking membrane-inserted hydrophobic helices upon helix-helix interaction.
Topics: Amino Acid Sequence; Aspartic Acid; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Lysine; Membranes, Artificial; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Spectrometry, Fluorescence; Static Electricity; Tryptophan | 2003 |
The role of tryptophan residues in an integral membrane protein: diacylglycerol kinase.
Topics: Bromine; Cell Membrane; Circular Dichroism; Diacylglycerol Kinase; Escherichia coli; Glycerol; Kinetics; Leucine; Lipid Bilayers; Models, Chemical; Mutation; Phosphatidylcholines; Plasmids; Protein Conformation; Spectrometry, Fluorescence; Temperature; Time Factors; Tryptophan | 2003 |
Orientation and conformation of cell-penetrating peptide penetratin in phospholipid vesicle membranes determined by polarized-light spectroscopy.
Topics: Carrier Proteins; Cell Membrane Permeability; Cell-Penetrating Peptides; Light; Liposomes; Models, Molecular; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Protein Conformation; Spectrum Analysis; Tryptophan | 2003 |
Lipid-protein interactions studied by introduction of a tryptophan residue: the mechanosensitive channel MscL.
Topics: Amino Acid Substitution; Binding Sites; Bromine; Cardiolipins; Escherichia coli; Escherichia coli Proteins; Ion Channels; Lipid Bilayers; Mechanotransduction, Cellular; Mycobacterium tuberculosis; Osmotic Pressure; Phenylalanine; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Phospholipids; Spectrometry, Fluorescence; Tryptophan | 2003 |
Tryptophan spectroscopy studies and black lipid bilayer analysis indicate that the oligomeric structure of Cry1Ab toxin from Bacillus thuringiensis is the membrane-insertion intermediate.
Topics: Acrylamide; Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Endotoxins; Hemolysin Proteins; Ion Channels; Lipid Bilayers; Liposomes; Membrane Proteins; Phosphatidylcholines; Phospholipids; Solutions; Spectrometry, Fluorescence; Tryptophan; Water | 2004 |
Phosphatidylinositol-specific phospholipase C forms different complexes with monodisperse and micellar phosphatidylcholine.
Topics: Bacillus cereus; Calorimetry; Chromatography, Gel; Fluorescence Resonance Energy Transfer; Hydrolysis; Kinetics; Micelles; Models, Chemical; Molecular Weight; Phosphatidylcholines; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Substrate Specificity; Surface Properties; Tryptophan | 2004 |
Cross-linking phosphatidylinositol-specific phospholipase C traps two activating phosphatidylcholine molecules on the enzyme.
Topics: Bacillus subtilis; Cross-Linking Reagents; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Micelles; Models, Molecular; Phosphatidylcholines; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphotransferases; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomyces; Time Factors; Tryptophan | 2004 |
Membrane interaction and cellular internalization of penetratin peptides.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Carrier Proteins; Cell Line; Cell-Penetrating Peptides; Circular Dichroism; Dogs; Egg Yolk; Fluoresceins; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Lipid Bilayers; Membranes; Microscopy, Confocal; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan | 2004 |
Membrane binding and translocation of cell-penetrating peptides.
Topics: Acrylamide; Amino Acid Sequence; Bromine; Carrier Proteins; Cell Membrane Permeability; Cell-Penetrating Peptides; Coumarins; Fluorescence Resonance Energy Transfer; Gene Products, tat; Lipid Bilayers; Lysophospholipids; Membrane Microdomains; Molecular Sequence Data; Oligonucleotides; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Conformation; Protein Transport; Spectrometry, Fluorescence; Tryptophan | 2004 |
An apolipoprotein AI mimetic peptide: membrane interactions and the role of cholesterol.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Buffers; Calorimetry, Differential Scanning; Centrifugation; Cholesterol; Circular Dichroism; Lipid Bilayers; Membrane Lipids; Membranes; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Protein Structure, Tertiary; Solutions; Tryptophan | 2004 |
The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacterial Proteins; Bacterial Toxins; Cholesterol; Cytotoxins; Ergosterol; Hydrogen; Kinetics; Lanosterol; Lipid Bilayers; Liposomes; Models, Chemical; Models, Molecular; Molecular Sequence Data; Neutrons; Phosphatidylcholines; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Streptococcus pneumoniae; Streptolysins; Tryptophan; Virulence Factors; Water | 2004 |
Phospholipid-lysozyme coating for chiral separation in capillary electrophoresis.
Topics: Electrophoresis, Capillary; Liposomes; Muramidase; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Tryptophan | 2004 |
Position and ionization state of Asp in the core of membrane-inserted alpha helices control both the equilibrium between transmembrane and nontransmembrane helix topography and transmembrane helix positioning.
Topics: Aspartic Acid; Circular Dichroism; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ions; Liposomes; Membrane Lipids; Membrane Proteins; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan | 2004 |
Monitoring gramicidin conformations in membranes: a fluorescence approach.
Topics: Gramicidin; Ion Channels; Liposomes; Membranes, Artificial; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 2004 |
Vesicle membrane interactions of penetratin analogues.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antennapedia Homeodomain Protein; Arginine; Carrier Proteins; Cell-Penetrating Peptides; Circular Dichroism; Drosophila Proteins; Homeodomain Proteins; Liposomes; Lysine; Molecular Sequence Data; Nuclear Proteins; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Polyethylene Glycols; Protein Binding; Protein Conformation; Protein Isoforms; Static Electricity; Transcription Factors; Tryptophan | 2004 |
Two homologous apolipoprotein AI mimetic peptides. Relationship between membrane interactions and biological activity.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Biophysical Phenomena; Biophysics; Calorimetry, Differential Scanning; Cell Membrane; Centrifugation; Cholesterol; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Hydrogen-Ion Concentration; Ligands; Lipid Bilayers; Lipids; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptides; Phosphatidylcholines; Polymorphism, Genetic; Protein Conformation; Protein Denaturation; Protons; Pyrenes; Temperature; Time Factors; Tryptophan | 2004 |
Interaction of melittin with membrane cholesterol: a fluorescence approach.
Topics: Binding Sites; Cholesterol; Kinetics; Liposomes; Macromolecular Substances; Melitten; Membrane Proteins; Membranes, Artificial; Phosphatidylcholines; Protein Binding; Spectrometry, Fluorescence; Tryptophan | 2004 |
Influence of the lipid composition on the kinetics of concerted insertion and folding of melittin in bilayers.
Topics: Animals; Bees; Cholesterol; Kinetics; Lipid Bilayers; Melitten; Membrane Proteins; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Folding; Protein Structure, Secondary; Tryptophan | 2004 |
Strength of integration of transmembrane alpha-helical peptides in lipid bilayers as determined by atomic force spectroscopy.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Alanine; Leucine; Lipid Bilayers; Membrane Proteins; Membranes; Microscopy, Atomic Force; Models, Chemical; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Protein Structure, Tertiary; Tryptophan; Water | 2004 |
Specific interactions of tryptophan with phosphatidylcholine and digalactosyldiacylglycerol in pure and mixed bilayers in the dry and hydrated state.
Topics: Egg Yolk; Galactolipids; Lipid Bilayers; Liposomes; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared; Surface Properties; Temperature; Tryptophan; Water | 2004 |
Caveolin scaffolding region and cholesterol-rich domains in membranes.
Topics: Amino Acid Motifs; Amino Acid Sequence; Calorimetry, Differential Scanning; Caveolin 1; Caveolins; Cell Membrane; Cholesterol; Circular Dichroism; Crystallization; Crystallography, X-Ray; Fluorescence Resonance Energy Transfer; Lipids; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Temperature; Tryptophan | 2005 |
Essential residues, W177 and R198, of LukF for phosphatidylcholine-binding and pore-formation by staphylococcal gamma-hemolysin on human erythrocyte membranes.
Topics: Arginine; Bacterial Proteins; Bacterial Toxins; Circular Dichroism; Cytotoxins; Dimerization; Erythrocyte Membrane; Erythrocytes; Fluorescence Resonance Energy Transfer; Hemolysin Proteins; Hemolysis; Humans; Kinetics; Leukocidins; Membrane Glycoproteins; Models, Molecular; Mutation; Perforin; Phosphatidylcholines; Pore Forming Cytotoxic Proteins; Potassium; Protein Binding; Protein Conformation; Protein Structure, Secondary; Tryptophan | 2004 |
A detergent-like mechanism of action of the cytolytic toxin Cyt1A from Bacillus thuringiensis var. israelensis.
Topics: Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Detergents; Electrophoresis, Polyacrylamide Gel; Endotoxins; Fluorescence Polarization; Fluorescence Resonance Energy Transfer; Hemolysin Proteins; Liposomes; Membrane Lipids; Membrane Potentials; Microscopy, Fluorescence; Molecular Weight; Osmotic Pressure; Phosphatidylcholines; Protein Binding; Static Electricity; Tryptophan; Tyrosine | 2005 |
Topography of diphtheria toxin A chain inserted into lipid vesicles.
Topics: 4-Chloro-7-nitrobenzofurazan; Bridged Bicyclo Compounds, Heterocyclic; Cysteine; Dimyristoylphosphatidylcholine; Diphtheria Toxin; Dithionite; Hydrogen-Ion Concentration; Lipid Bilayers; Membrane Fusion; Mutagenesis, Site-Directed; Peptide Fragments; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein Subunits; Protein Transport; Solutions; Spectrometry, Fluorescence; Tryptophan | 2005 |
A synergistic effect between cholesterol and tryptophan-flanked transmembrane helices modulates membrane curvature.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anisotropy; Cholesterol; Drug Synergism; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Chemical; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Tryptophan | 2005 |
The characterization of plasma membrane Ca2+-ATPase in rich sphingomyelin-cholesterol domains.
Topics: Acrylamide; Calcium-Transporting ATPases; Cell Membrane; Cholesterol; Fluorescence; Phase Transition; Phosphatidylcholines; Proteolipids; Spectrometry, Fluorescence; Sphingomyelins; Tryptophan | 2005 |
Point mutational analysis of the liganding site in human glycolipid transfer protein. Functionality of the complex.
Topics: Animals; Antigens, CD; Asparagine; Aspartic Acid; Binding Sites; Carrier Proteins; Cell Membrane; Chromatography, Affinity; Chromatography, Gel; DNA Mutational Analysis; Galactosylceramides; Glycolipids; Humans; Lactosylceramides; Leucine; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylcholines; Point Mutation; Protein Binding; Recombinant Fusion Proteins; Swine; Time Factors; Tryptophan | 2005 |
Interaction of C-terminal loop 13 of sodium-glucose cotransporter SGLT1 with lipid bilayers.
Topics: Fluorescence; Lipid Bilayers; Liposomes; Membrane Glycoproteins; Monosaccharide Transport Proteins; Mutation; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Sodium-Glucose Transporter 1; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan | 2005 |
Single-spanning membrane protein insertion in membrane mimetic systems: role and localization of aromatic residues.
Topics: Amino Acids, Aromatic; Anisotropy; Biomimetics; Glucosides; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Proteins; Micelles; Peptide Fragments; Phenylalanine; Phosphatidylcholines; Phosphatidylserines; Proton-Translocating ATPases; Spectrometry, Fluorescence; Tryptophan; Tyrosine; Yeasts | 2005 |
Unfolding and extraction of a transmembrane alpha-helical peptide: dynamic force spectroscopy and molecular dynamics simulations.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Carnitine; Cell Adhesion; Cell Membrane; Computer Simulation; Hot Temperature; Lipid Bilayers; Microscopy, Atomic Force; Models, Molecular; Molecular Conformation; Peptides; Phosphatidylcholines; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Pyrenes; Spectrophotometry; Spectrum Analysis; Thermodynamics; Tryptophan | 2005 |
Membrane-bound conformation of M13 major coat protein: a structure validation through FRET-derived constraints.
Topics: Capsid Proteins; Cell Membrane; Cysteine; Databases, Protein; Detergents; Fluorescence Resonance Energy Transfer; Lipid Bilayers; Micelles; Models, Molecular; Models, Statistical; Molecular Conformation; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan; X-Ray Diffraction | 2005 |
Interfacial tryptophan residues: a role for the cation-pi effect?
Topics: Amino Acids; Cations; Computer Simulation; Lipid Bilayers; Membrane Fluidity; Membrane Proteins; Models, Chemical; Models, Molecular; Phosphatidylcholines; Phosphatidylethanolamines; Protein Conformation; Tryptophan; Water | 2005 |
Properties and structures of the influenza and HIV fusion peptides on lipid membranes: implications for a role in fusion.
Topics: Amino Acid Sequence; Anisotropy; Cell Membrane; Chloroform; Circular Dichroism; Dose-Response Relationship, Drug; Hemagglutinin Glycoproteins, Influenza Virus; HIV Envelope Protein gp41; Lipid Bilayers; Lipids; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Phosphatidylcholines; Polyethylene Glycols; Protein Structure, Secondary; Recombinant Fusion Proteins; Spectrophotometry, Infrared; Tryptophan; Water | 2005 |
Effect of tryptophan oligopeptides on the size distribution of POPC liposomes: a dynamic light scattering and turbidimetric study.
Topics: Indoles; Light; Liposomes; Nephelometry and Turbidimetry; Oligopeptides; Particle Size; Phosphatidylcholines; Tryptophan | 2005 |
The cell penetrating peptides pVEC and W2-pVEC induce transformation of gel phase domains in phospholipid bilayers without affecting their integrity.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Calcitonin; Cell Membrane; Cell Membrane Permeability; Cell Physiological Phenomena; Cytosol; Endocytosis; Fluorescence Polarization; Gels; Humans; Leucine; Lipid Bilayers; Models, Biological; Murinae; Peptides; Phosphatidylcholines; Phospholipids; Point Mutation; Time Factors; Tryptophan | 2006 |
Identification of membrane-contacting loops of the catalytic domain of cytochrome P450 2C2 by tryptophan fluorescence scanning.
Topics: Catalytic Domain; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Liposomes; Membrane Proteins; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylcholines; Spectrometry, Fluorescence; Spin Labels; Tryptophan | 2006 |
Peroxidase activity and structural transitions of cytochrome c bound to cardiolipin-containing membranes.
Topics: Acridine Orange; Animals; Binding, Competitive; Cardiolipins; Cell Membrane; Cytochromes c; Electrophoresis; Enzyme Activation; Etoposide; Fluoresceins; Horses; Hydrophobic and Hydrophilic Interactions; Lipids; Liposomes; Osmolar Concentration; Oxidation-Reduction; Peroxidase; Phosphatidylcholines; Spectrometry, Fluorescence; Structure-Activity Relationship; Time Factors; Tryptophan | 2006 |
Membrane interactions of cell-penetrating peptides probed by tryptophan fluorescence and dichroism techniques: correlations of structure to cellular uptake.
Topics: Animals; Cell Line; Cell Line, Tumor; Cholesterol; Circular Dichroism; Cricetinae; Lipid Bilayers; Membranes; Peptides; Phosphatidylcholines; Protein Binding; Protein Conformation; Quantum Theory; Rats; Spectrometry, Fluorescence; Tryptophan | 2006 |
Shiga toxin B-subunit sequential binding to its natural receptor in lipid membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Binding Sites; Buffers; Circular Dichroism; Escherichia coli; Globosides; Models, Chemical; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Conformation; Recombinant Proteins; Shiga Toxin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Trihexosylceramides; Tryptophan; Unilamellar Liposomes; Water | 2007 |
Modulation of gramicidin channel conformation and organization by hydrophobic mismatch in saturated phosphatidylcholine bilayers.
Topics: Acrylamide; Centrifugation, Density Gradient; Circular Dichroism; Gramicidin; Hydrophobic and Hydrophilic Interactions; Ion Channels; Lipid Bilayers; Phosphatidylcholines; Protein Structure, Quaternary; Spectrometry, Fluorescence; Time Factors; Tryptophan | 2007 |
Interaction of beta2-glycoprotein 1 with phosphatidylserine-containing membranes: ligand-dependent conformational alterations initiate bivalent binding.
Topics: Animals; beta 2-Glycoprotein I; Cattle; Chemical Precipitation; Electrophoresis, Polyacrylamide Gel; Energy Transfer; Humans; Kinetics; Ligands; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Deletion; Structure-Activity Relationship; Tryptophan; Unilamellar Liposomes | 2007 |
A fluorescence method to define transmembrane alpha-helices in membrane proteins: studies with bacterial diacylglycerol kinase.
Topics: Algorithms; Amino Acid Substitution; Cell Membrane; Cysteine; Diacylglycerol Kinase; Escherichia coli; Escherichia coli Proteins; Fluorescent Dyes; Glycerol; Lipid Bilayers; Membrane Proteins; Models, Molecular; Mutagenesis, Site-Directed; Oxadiazoles; Phosphatidylcholines; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan | 2007 |
Membrane binding of pH-sensitive influenza fusion peptides. positioning, configuration, and induced leakage in a lipid vesicle model.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Hemagglutinin Glycoproteins, Influenza Virus; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Membrane Fusion; Models, Biological; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan; Unilamellar Liposomes | 2007 |
Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic.
Topics: Alanine; Anti-Bacterial Agents; Bacteriocins; Cell Membrane; Coated Vesicles; Diphosphates; Fluoresceins; Lactococcus lactis; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Succinic Acid; Sulfides; Tryptophan; Uridine Diphosphate N-Acetylmuramic Acid | 2008 |
The hierarchy of structural transitions induced in cytochrome c by anionic phospholipids determines its peroxidase activation and selective peroxidation during apoptosis in cells.
Topics: Animals; Apoptosis; Cardiolipins; Cytochromes c; Electron Spin Resonance Spectroscopy; Enzyme Activation; Etoposide; Fluorescence; Heme; Humans; Mice; Peroxidase; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylserines; Phospholipids; Protein Structure, Tertiary; Tryptophan | 2007 |
Membrane-bound peptides from V-ATPase subunit a do not interact with an indole-type inhibitor.
Topics: Acrylamide; Amino Acid Sequence; Amino Acids; Arginine; Fluorescence Resonance Energy Transfer; Indoles; Lipid Bilayers; Lipids; Membrane Proteins; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Piperidines; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan; Vacuolar Proton-Translocating ATPases | 2008 |
A fluorescence approach of the gamma radiation effects on gramicidin A inserted in liposomes.
Topics: Fluorescence; Free Radicals; Gamma Rays; Gramicidin; Lipid Peroxidation; Liposomes; Phosphatidylcholines; Tryptophan | 2008 |
Lipid-rhodopsin hydrophobic mismatch alters rhodopsin helical content.
Topics: Animals; Cattle; Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Kinetics; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Photolysis; Protein Denaturation; Protein Structure, Secondary; Rhodopsin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan | 2008 |
An atomic force microscopy study of the interactions between indolicidin and supported planar bilayers.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Coloring Agents; Dose-Response Relationship, Drug; Fluoresceins; Hydrogen-Ion Concentration; Lipid Bilayers; Lipids; Membrane Fluidity; Microscopy, Atomic Force; Peptides; Phosphatidylcholines; Phospholipids; Tryptophan | 2008 |
Molecular dynamics simulations reveal that AEDANS is an inert fluorescent probe for the study of membrane proteins.
Topics: Capsid Proteins; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Lipid Bilayers; Membrane Proteins; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Mutation; Naphthalenesulfonates; Phosphatidylcholines; Probability; Protein Conformation; Time Factors; Tryptophan | 2010 |
Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Binding Sites; Blotting, Western; Catalytic Domain; Cell Line; Cell Nucleus; Enzyme Stability; Humans; Microfilament Proteins; Models, Molecular; Molecular Chaperones; Monocytes; Mutation; Phosphatidylcholines; Protein Binding; Protein Structure, Tertiary; Thermolysin; Tryptophan | 2009 |
Structural characterization of the transmembrane proximal region of the hepatitis C virus E1 glycoprotein.
Topics: Amino Acid Sequence; Cell Membrane; Circular Dichroism; Electron Spin Resonance Spectroscopy; Glycoproteins; Hepacivirus; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Protein Structure, Secondary; Sequence Alignment; Spectrometry, Fluorescence; Spin Labels; Tryptophan; Viral Envelope Proteins | 2010 |
The effect of hydrophilic substitutions and anionic lipids upon the transverse positioning of the transmembrane helix of the ErbB2 (neu) protein incorporated into model membrane vesicles.
Topics: Amino Acid Sequence; Amino Acid Substitution; Anions; Hydrogen-Ion Concentration; Membrane Lipids; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Mutation; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Receptor, ErbB-2; Spectrometry, Fluorescence; Tryptophan; Unilamellar Liposomes | 2010 |
Role of membranotropic sequences from herpes simplex virus type I glycoproteins B and H in the fusion process.
Topics: Amino Acid Sequence; Buffers; Cholesterol; Circular Dichroism; Herpesvirus 1, Human; Isomerism; Kinetics; Lipid Bilayers; Membrane Fusion; Models, Chemical; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Spectrometry, Fluorescence; Spin Labels; Surface Plasmon Resonance; Tryptophan; Viral Envelope Proteins | 2010 |
Recognition and binding of a helix-loop-helix peptide to carbonic anhydrase occurs via partly folded intermediate structures.
Topics: Algorithms; Benzenesulfonamides; Carbonic Anhydrase II; Energy Transfer; Fluorescence; Fluorescence Polarization; Helix-Loop-Helix Motifs; Humans; Peptides; Phosphatidylcholines; Probability; Protein Binding; Protein Conformation; Protein Folding; Rotation; Spectrometry, Fluorescence; Sulfonamides; Time Factors; Tryptophan; Water | 2010 |
Structural characterization of two pore-forming peptides: consequences of introducing a C-terminal tryptophan.
Topics: Anions; Chloride Channels; Chlorides; Computational Biology; Databases, Protein; Drug Discovery; Electrochemical Techniques; Ion Transport; Kinetics; Lipid Bilayers; Micelles; Models, Molecular; Molecular Dynamics Simulation; Molecular Mimicry; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphatidylcholines; Protein Conformation; Receptors, Glycine; Tryptophan | 2010 |
Structure and orientation of a voltage-sensor toxin in lipid membranes.
Topics: Amino Acid Sequence; Animals; DNA Mutational Analysis; Fluorescence; Ion Channel Gating; Membrane Lipids; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Spectrum Analysis; Spider Venoms; Tryptophan | 2010 |
Interpretation of 2H-NMR experiments on the orientation of the transmembrane helix WALP23 by computer simulations.
Topics: Cell Membrane; Computer Simulation; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphatidylcholines; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Secondary; Rotation; Time Factors; Tryptophan | 2010 |
Membrane insertion topology of the central apolipoprotein A-I region. Fluorescence studies using single tryptophan mutants.
Topics: Apolipoprotein A-I; Dimyristoylphosphatidylcholine; Fluorescence Polarization; Humans; Lipid Bilayers; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylcholines; Predictive Value of Tests; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Protein Transport; Repetitive Sequences, Amino Acid; Spectrometry, Fluorescence; Tryptophan | 2011 |
The binding of 14-3-3γ to membranes studied by intrinsic fluorescence spectroscopy.
Topics: 14-3-3 Proteins; Amino Acid Substitution; Binding Sites; Humans; Lipid Bilayers; Liposomes; Models, Molecular; Mutation, Missense; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tryptophan | 2011 |
Transmembrane extension and oligomerization of the CLIC1 chloride intracellular channel protein upon membrane interaction.
Topics: Algorithms; Chloride Channels; Cholesterol; Cysteine; Dimerization; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Lipid Bilayers; Liposomes; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Oxidation-Reduction; Phosphatidylcholines; Protein Conformation; Protein Interaction Domains and Motifs; Protein Unfolding; Recombinant Proteins; Tryptophan | 2011 |
Properties of membrane-incorporated WALP peptides that are anchored on only one end.
Topics: Amino Acid Sequence; Dimyristoylphosphatidylcholine; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Tryptophan | 2012 |
Structural modulation of phosducin by phosphorylation and 14-3-3 protein binding.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; Eye Proteins; GTP-Binding Protein Regulators; Humans; Molecular Sequence Data; Phosphatidylcholines; Phosphoproteins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Rats; Serine; Spectrometry, Fluorescence; Tryptophan | 2012 |
Validation of depth-dependent fluorescence quenching in membranes by molecular dynamics simulation of tryptophan octyl ester in POPC bilayer.
Topics: Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Phosphatidylcholines; Spectrometry, Fluorescence; Tryptophan | 2013 |
Multiple membrane interactions and versatile vesicle deformations elicited by melittin.
Topics: Animals; Chemical Phenomena; Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Insect Proteins; Kinetics; Lipid Bilayers; Liposomes; Melitten; Membrane Proteins; Membranes; Microscopy, Electron, Transmission; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Protein Structure, Secondary; Solubility; Surface Properties; Tryptophan | 2013 |
Membrane bound α-synuclein is fully embedded in the lipid bilayer while segments with higher flexibility remain.
Topics: Acrylamide; alpha-Synuclein; Amino Acid Sequence; Cell Membrane; Humans; Lipid Bilayers; Lipids; Micelles; Molecular Sequence Data; Parkinson Disease; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Tertiary; Tryptophan | 2013 |
Membrane remodeling by α-synuclein and effects on amyloid formation.
Topics: Adenosine; alpha-Synuclein; Amyloid; Cholesterol; Circular Dichroism; Glycerophospholipids; Indicators and Reagents; Lipid Bilayers; Lipids; Membranes, Artificial; Microscopy, Electron, Transmission; Microtubules; Neutrons; Phosphatidylcholines; Spectrophotometry, Ultraviolet; Tryptophan | 2013 |
Importance of indole N-H hydrogen bonding in the organization and dynamics of gramicidin channels.
Topics: Amino Acid Sequence; Circular Dichroism; Gramicidin; Hydrogen Bonding; Indoles; Lipid Bilayers; Models, Biological; Molecular Sequence Data; Phosphatidylcholines; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tryptophan | 2014 |
Peptide-membrane interactions of arginine-tryptophan peptides probed using quartz crystal microbalance with dissipation monitoring.
Topics: Amino Acid Sequence; Arginine; Cell Membrane; Liposomes; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Quartz Crystal Microbalance Techniques; Tryptophan | 2014 |
Two-channel dansyl/tryptophan emitters with a cholic acid bridge as reporters for local hydrophobicity within supramolecular systems based on bile salts.
Topics: Bile Acids and Salts; Cholic Acid; Energy Transfer; Fluorescent Dyes; Hydrophobic and Hydrophilic Interactions; Phosphatidylcholines; Spectrometry, Fluorescence; Tryptophan | 2014 |
Fluorescence study of domain structure and lipid interaction of human apolipoproteins E3 and E4.
Topics: 2-Naphthylamine; Animals; Apolipoprotein E3; Apolipoprotein E4; Chickens; Fluorescence Resonance Energy Transfer; Guanidine; Humans; Kinetics; Lipids; Phosphatidylcholines; Protein Denaturation; Protein Isoforms; Protein Stability; Protein Structure, Tertiary; Pyrenes; Time Factors; Tryptophan; Unilamellar Liposomes | 2014 |
The role of tryptophans on the cellular uptake and membrane interaction of arginine-rich cell penetrating peptides.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Membrane; Cell Membrane Permeability; Cell Survival; Cell-Penetrating Peptides; CHO Cells; Cricetulus; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Phenylalanine; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Structure, Secondary; Protein Transport; Static Electricity; Structure-Activity Relationship; Tryptophan | 2015 |
Equivalent Isopropanol Concentrations of Aromatic Amino Acids Interactions with Lipid Vesicles.
Topics: 2-Propanol; Glycerylphosphorylcholine; Magnetic Resonance Spectroscopy; Phenylalanine; Phosphatidylcholines; Phosphatidylserines; Tryptophan; Tyrosine | 2015 |
Inhibition of cancer cell proliferation and breast tumor targeting of pHLIP-monomethyl auristatin E conjugates.
Topics: Aminobenzoates; Animals; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Chemistry, Pharmaceutical; Circular Dichroism; Drug Delivery Systems; Female; HeLa Cells; Humans; Hydrogen-Ion Concentration; Membrane Proteins; Mice; Neoplasm Transplantation; Oligopeptides; Peptides; Phosphatidylcholines; Spectrometry, Fluorescence; Triple Negative Breast Neoplasms; Tryptophan | 2015 |
Properties of the Mechanosensitive Channel MscS Pore Revealed by Tryptophan Scanning Mutagenesis.
Topics: Escherichia coli Proteins; Fluorescence Polarization; Ion Channels; Liposomes; Models, Molecular; Mutagenesis, Site-Directed; Permeability; Phosphatidylcholines; Protein Conformation; Protein Stability; Tryptophan | 2015 |
Permeation of the three aromatic dipeptides through lipid bilayers: Experimental and computational study.
Topics: Hydrogen-Ion Concentration; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phenylalanine; Phosphatidylcholines; Temperature; Time Factors; Tryptophan; Tyrosine; Water | 2016 |
Synthesis and characterization of β-peptide helices as transmembrane domains in lipid model membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Dimyristoylphosphatidylcholine; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Methanol; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Solid-Phase Synthesis Techniques; Solvents; Spectrometry, Fluorescence; Trifluoroethanol; Tryptophan; Unilamellar Liposomes | 2016 |
Cord Blood Metabolic Signatures of Birth Weight: A Population-Based Study.
Topics: Birth Weight; Carnitine; Chromatography, High Pressure Liquid; Cohort Studies; Docosahexaenoic Acids; Environmental Exposure; Europe; Female; Fetal Blood; Fetal Development; Fetus; Humans; Indoles; Infant, Newborn; Male; Mass Spectrometry; Metabolome; Particulate Matter; Phosphatidylcholines; Pregnancy; Progesterone; Prostaglandins; Reference Standards; Tryptophan; Vitamin A | 2018 |
Metabolite amyloid-like fibrils interact with model membranes.
Topics: Adenine; Alanine; Anisotropy; Diphenylhexatriene; Fluorescence; HEK293 Cells; Humans; Hydrogen Bonding; Lipid Bilayers; Macromolecular Substances; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylserines; Polyacetylene Polymer; Polymers; Polyynes; Tryptophan; Tyrosine | 2018 |
Effects of GM1 on brain spectrin-aminophospholipid interactions.
Topics: Animals; Brain; Cell Membrane; Circular Dichroism; Dimyristoylphosphatidylcholine; G(M1) Ganglioside; Kinetics; Lipids; Micelles; Oligosaccharides; Phosphatidylcholines; Phosphatidylethanolamines; Pressure; Protein Binding; Sheep; Spectrin; Spectrometry, Fluorescence; Temperature; Tryptophan | 2019 |
Quenching of tryptophan fluorescence in a highly scattering solution: Insights on protein localization in a lung surfactant formulation.
Topics: Algorithms; Fluorescence; Humans; Lipid Bilayers; Models, Theoretical; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; Pulmonary Surfactants; Tryptophan | 2018 |
Wavelength-Selective Fluorescence of a Model Transmembrane Peptide: Constrained Dynamics of Interfacial Tryptophan Anchors.
Topics: Amino Acid Sequence; Membrane Proteins; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan | 2018 |
A serum metabolomics signature of hypothermia fatalities involving arginase activity, tryptophan content, and phosphatidylcholine saturation.
Topics: Adult; Aged; Aged, 80 and over; Arginase; Biomarkers; Case-Control Studies; Chromatography, Liquid; Female; Humans; Hypothermia; Male; Metabolomics; Middle Aged; Phosphatidylcholines; Tandem Mass Spectrometry; Tryptophan | 2019 |
A Non-Targeted LC-MS Profiling Reveals Elevated Levels of Carnitine Precursors and Trimethylated Compounds in the Cord Plasma of Pre-Eclamptic Infants.
Topics: Adult; Biomarkers; Carnitine; Case-Control Studies; Chromatography, Liquid; Creatine; Cross-Sectional Studies; Female; Fetal Blood; Humans; Infant, Newborn; Metabolomics; Phosphatidylcholines; Pre-Eclampsia; Pregnancy; Principal Component Analysis; Putrescine; Pyridoxic Acid; Tandem Mass Spectrometry; Tryptophan; Urea | 2018 |
Preferential Equilibrium Partitioning of Positively Charged Tryptophan into Phosphatidylcholine Bilayer Membranes.
Topics: Lipid Bilayers; Molecular Conformation; Phosphatidylcholines; Tryptophan | 2019 |
Glucosylceramide acyl chain length is sensed by the glycolipid transfer protein.
Topics: Animals; Carrier Proteins; Cattle; Escherichia coli; Glucosylceramides; Membranes, Artificial; Molecular Structure; Phosphatidylcholines; Protein Conformation; Surface Plasmon Resonance; Tryptophan | 2018 |
Synthesis and application of the blue fluorescent amino acid l-4-cyanotryptophan to assess peptide-membrane interactions.
Topics: Amino Acid Sequence; Cell Membrane; Fluorescence; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; HeLa Cells; Humans; Membrane Proteins; Microscopy, Fluorescence; Phosphatidylcholines; Protein Binding; Tryptophan; Unilamellar Liposomes | 2019 |
Structure and dynamics at N- and C-terminal regions of intrinsically disordered human c-Myc PEST degron reveal a pH-induced transition.
Topics: Amino Acid Sequence; Aspartic Acid; Cloning, Molecular; Cysteine; Escherichia coli; Gene Expression; Genetic Vectors; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Indoles; Intrinsically Disordered Proteins; Molecular Dynamics Simulation; Neoplasm Proteins; Phosphatidylcholines; Protein Folding; Protein Structure, Secondary; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Spectrometry, Fluorescence; Staining and Labeling; Tryptophan | 2020 |
Physico-chemical interactions of a new rod-coil-rod polymer with liposomal system: Approaches to applications in tryptophan-related therapies.
Topics: Antineoplastic Agents; Chemistry, Physical; Cholesterol; Humans; Liposomes; Molecular Structure; Neoplasms; Phosphatidylcholines; Polyethylene Glycols; Polymers; Tryptophan | 2021 |
Potential Anti-Alzheimer Agents from Guanidinyl Tryptophan Derivatives with Activities of Membrane Adhesion and Conformational Transition Inhibitions.
Topics: Adhesiveness; Adsorption; Alzheimer Disease; Amyloid beta-Peptides; Cell Membrane; Guanidine; Humans; Ligands; Lipid Bilayers; Lipids; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Tryptophan; Water | 2021 |
The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes.
Topics: Apoptosis Regulatory Proteins; Basigin; Cell Membrane; Cryoelectron Microscopy; Humans; Hydrophobic and Hydrophilic Interactions; Membrane Proteins; Models, Molecular; Multiprotein Complexes; Phosphatidylcholines; Phospholipid Transfer Proteins; Phospholipids; Protein Structure, Tertiary; Tryptophan | 2021 |
Intestinal metabolomics of juvenile lenok (Brachymystax lenok) in response to heat stress.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acetylcarnitine; Animals; Aspartic Acid; Erucic Acids; Glucose; Glutamine; Heat-Shock Response; Histidine; Intestines; Lactates; Leucine; Methionine; Oxylipins; Palmitoylcarnitine; Phenylalanine; Phosphatidylcholines; Phosphorylcholine; Proline; Salmonidae; Tandem Mass Spectrometry; Tryptophan; Tyrosine | 2022 |
Potential novel biomarkers in small intestine for obesity/obesity resistance revealed by multi-omics analysis.
Topics: Animals; Biomarkers; Blood Glucose; Diet, High-Fat; Enkephalins; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Phosphatidylcholines; Phosphatidylethanolamines; Propanols; Tryptophan | 2022 |
Determination of the boundary lipids of sticholysins using tryptophan quenching.
Topics: Animals; Cnidarian Venoms; Organic Chemicals; Phosphatidylcholines; Sea Anemones; Sphingomyelins; Tryptophan | 2022 |