Page last updated: 2024-09-05

phosphatidylcholines and trimethyloxamine

phosphatidylcholines has been researched along with trimethyloxamine in 26 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(trimethyloxamine)
Trials
(trimethyloxamine)
Recent Studies (post-2010) (trimethyloxamine)
32,2044435,5931,573751,161

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.85)29.6817
2010's18 (69.23)24.3611
2020's7 (26.92)2.80

Authors

AuthorsStudies
Seibel, BA; Walsh, PJ1
Rader, DJ; Rak, K1
Allayee, H; Bennett, BJ; Britt, EB; Chung, YM; DiDonato, JA; Dugar, B; Feldstein, AE; Fu, X; Hazen, SL; Klipfell, E; Koeth, R; Levison, BS; Lusis, AJ; Schauer, P; Smith, JD; Tang, WH; Wang, Z; Wu, Y1
Britt, EB; Fu, X; Hazen, SL; Koeth, RA; Levison, BS; Tang, WH; Wang, Z; Wu, Y1
Loscalzo, J1
Ma, X; Wang, F; Wang, M; Wang, Y; Zhao, C; Zhao, M1
Arduini, A; Lopaschuk, GD; Ussher, JR1
Hazen, SL; Tang, WH1
Borowski, AG; Hazen, SL; Klein, AL; Shrestha, K; Tang, WH; Troughton, RW; Wang, Z; Wu, Y1
Brown, JM; Hazen, SL1
Drosos, I; Kolios, G; Tavridou, A1
Quante, M1
Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y1
Hennig, B; Hoffman, JB; Morris, AJ; Perkins, JT; Petriello, MC; Sunkara, M; Wahlang, B1
Albert, CM; Hu, FB; Li, Y; Manson, JE; Qi, L; Rexrode, KM; Rimm, EB; Zheng, Y1
Fricker, G; Garbade, SF; Kratzer, F; Langhans, CD; Okun, JG; Schmidt, KV; Schuhmann, V; Stremmel, W1
Esteras, R; Fernandez-Prado, R; Gonzalez-Parra, E; Gracia-Iguacel, C; Ortiz, A; Perez-Gomez, MV; Sanchez-Niño, MD; Sanz, AB1
Gupta, A; Netz, RR; Pham, QD; Schlaich, A; Schneck, E; Sparr, E; Wolde-Kidan, A1
Gloor, GB; Joris, BR1
Feng, Z; Miller, HL; Quan, L; Shi, XT; Yi, J; Zhang, F; Zhao, Y1
He, Y; Huang, L; Li, D; Rong, Y; Wu, Z; Zeng, Q; Zhang, H1
Aardema, NDJ; Aguilar, SS; Bergeson, JR; Bunnell, ML; Caudill, MA; Cho, CE; Larson, DP; Lefevre, M; Malysheva, OV1
Fu, X; Graham, B; Hazen, SL; Li, L; Li, XS; Neale, S; O'Laughlin, C; Peterson, K; Shelkay, S; Skye, SM; Tang, WHW; Wilcox, J; Zabell, A1
Kiatchoosakun, S; Phetcharaburanin, J; Phrommintikul, A; Senthong, V; Sritara, P; Tatsanavivat, P; Wongvipaporn, C1
Kang, JW; Zivkovic, AM1
Bernhard, W; Böckmann, KA; Franz, AR; Minarski, M; Poets, CF; Shunova, A; Wiechers, C1

Reviews

8 review(s) available for phosphatidylcholines and trimethyloxamine

ArticleYear
Trimethylamine oxide accumulation in marine animals: relationship to acylglycerol storage.
    The Journal of experimental biology, 2002, Volume: 205, Issue:Pt 3

    Topics: Animals; Diglycerides; Glycerides; Hydrolysis; Marine Biology; Methylamines; Phosphatidylcholines; Plants; Sharks; Triglycerides

2002
Gut microbiota metabolism of L-carnitine and cardiovascular risk.
    Atherosclerosis, 2013, Volume: 231, Issue:2

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Dietary Supplements; Humans; Insulin Resistance; Intestines; Liver; Methylamines; Mice; Microbiota; Muscle, Skeletal; Myocardial Ischemia; Phosphatidylcholines; Risk

2013
The contributory role of gut microbiota in cardiovascular disease.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:10

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Choline; Diet; Female; Food; Humans; Intestines; Male; Methylamines; Microbiota; Oxygenases; Phosphatidylcholines

2014
The gut microbial endocrine organ: bacterially derived signals driving cardiometabolic diseases.
    Annual review of medicine, 2015, Volume: 66

    Topics: Bacteria; Cardiovascular Diseases; Diet; Endocrine System; Humans; Intestines; Methylamines; Microbiota; Phosphatidylcholines

2015
New aspects on the metabolic role of intestinal microbiota in the development of atherosclerosis.
    Metabolism: clinical and experimental, 2015, Volume: 64, Issue:4

    Topics: Animals; Atherosclerosis; Betaine; Carnitine; Choline; Humans; Intestinal Mucosa; Intestines; Methylamines; Microbiota; Phosphatidylcholines

2015
Nutrients Turned into Toxins: Microbiota Modulation of Nutrient Properties in Chronic Kidney Disease.
    Nutrients, 2017, May-12, Volume: 9, Issue:5

    Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Microbiome; Humans; Methylamines; Micronutrients; Oxalates; Phosphates; Phosphatidylcholines; Renal Insufficiency, Chronic; Tryptophan; Tyrosine

2017
Unaccounted risk of cardiovascular disease: the role of the microbiome in lipid metabolism.
    Current opinion in lipidology, 2019, Volume: 30, Issue:2

    Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Choline; Energy Metabolism; Fatty Acids, Volatile; Gastrointestinal Microbiome; Genomics; High-Throughput Nucleotide Sequencing; Humans; Lipid Metabolism; Metabolic Syndrome; Methylamines; Phosphatidylcholines; RNA, Ribosomal, 16S; T-Lymphocytes, Helper-Inducer; Triglycerides

2019
Are eggs good again? A precision nutrition perspective on the effects of eggs on cardiovascular risk, taking into account plasma lipid profiles and TMAO.
    The Journal of nutritional biochemistry, 2022, Volume: 100

    Topics: Bacteria; Biological Variation, Population; Cardiovascular Diseases; Cholesterol; Choline; Diet; Eggs; Gastrointestinal Microbiome; Heart Disease Risk Factors; Humans; Methylamines; Phosphatidylcholines

2022

Trials

3 trial(s) available for phosphatidylcholines and trimethyloxamine

ArticleYear
Effect of Choline Forms and Gut Microbiota Composition on Trimethylamine-
    Nutrients, 2020, Jul-25, Volume: 12, Issue:8

    Topics: Adult; Biomarkers; Cardiovascular Diseases; Choline; Cross-Over Studies; Diet; Dietary Supplements; Double-Blind Method; Female; Gastrointestinal Microbiome; Healthy Volunteers; Heart Disease Risk Factors; Humans; Male; Meals; Methylamines; Middle Aged; Phosphatidylcholines

2020
Dietary Choline Supplements, but Not Eggs, Raise Fasting TMAO Levels in Participants with Normal Renal Function: A Randomized Clinical Trial.
    The American journal of medicine, 2021, Volume: 134, Issue:9

    Topics: Adult; Choline; Diet; Drug Monitoring; Egg White; Egg Yolk; Female; Healthy Volunteers; Humans; Lipotropic Agents; Male; Methylamines; Phosphatidylcholines; Platelet Function Tests; Treatment Outcome

2021
Different choline supplement metabolism in adults using deuterium labelling.
    European journal of nutrition, 2023, Volume: 62, Issue:4

    Topics: Adult; Betaine; Choline; Cross-Over Studies; Deuterium; Fatty Acids; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Phosphatidylcholines; Phosphorylcholine; Prospective Studies

2023

Other Studies

15 other study(ies) available for phosphatidylcholines and trimethyloxamine

ArticleYear
Cardiovascular disease: the diet-microbe morbid union.
    Nature, 2011, Apr-07, Volume: 472, Issue:7341

    Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Choline; Diet; Dietary Fats; Gastrointestinal Tract; Humans; Liver; Metabolomics; Methylamines; Mice; Oxygenases; Phosphatidylcholines; Probiotics; Risk Assessment

2011
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
    Nature, 2011, Apr-07, Volume: 472, Issue:7341

    Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; Diet; Dietary Fats; Female; Gastrointestinal Tract; Gene Expression Regulation; Germ-Free Life; Humans; Liver; Macrophages; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Oxygenases; Phenotype; Phosphatidylcholines; Receptors, Scavenger; Risk Assessment

2011
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk.
    The New England journal of medicine, 2013, Apr-25, Volume: 368, Issue:17

    Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Betaine; Cardiovascular Diseases; Choline; Female; Humans; Intestinal Mucosa; Intestines; Kaplan-Meier Estimate; Male; Metagenome; Methylamines; Middle Aged; Phosphatidylcholines; Prospective Studies; Risk Factors

2013
Gut microbiota, the genome, and diet in atherogenesis.
    The New England journal of medicine, 2013, Apr-25, Volume: 368, Issue:17

    Topics: Anti-Bacterial Agents; Cardiovascular Diseases; Female; Humans; Intestines; Male; Metagenome; Methylamines; Phosphatidylcholines

2013
Metabonomics study of the therapeutic mechanism of Gynostemma pentaphyllum and atorvastatin for hyperlipidemia in rats.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Gynostemma; Heptanoic Acids; Hyperlipidemias; Lipid Metabolism; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylamines; Phosphatidylcholines; Phytotherapy; Plant Extracts; Pyrroles; Rats; Rats, Sprague-Dawley; Treatment Outcome; Triglycerides

2013
Intestinal microbiota-dependent phosphatidylcholine metabolites, diastolic dysfunction, and adverse clinical outcomes in chronic systolic heart failure.
    Journal of cardiac failure, 2015, Volume: 21, Issue:2

    Topics: Adult; Aged; Betaine; Biomarkers; Blood Pressure; Choline; Chronic Disease; Cohort Studies; Female; Heart Failure, Systolic; Humans; Intestinal Mucosa; Male; Methylamines; Microbiota; Middle Aged; Phosphatidylcholines; Prospective Studies; Risk Factors; Treatment Outcome

2015
You Are What You Eat: Metabolites of Gut Microbiota Provide Novel Insights into Diagnosis and Development of Chronic Kidney Disease.
    Transplantation, 2015, Volume: 99, Issue:7

    Topics: Animals; Bacteria; Biomarkers; Diet; Humans; Intestinal Mucosa; Intestines; Metabolomics; Methylamines; Microbiota; Phosphatidylcholines; Prognosis; Renal Insufficiency, Chronic; Risk Factors

2015
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:3

    Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors

2016
Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors.
    The Journal of nutritional biochemistry, 2016, Volume: 33

    Topics: Administration, Oral; Animals; Atherosclerosis; Biomarkers; Choline; Deuterium; Dietary Fats; Environmental Pollutants; Enzyme Induction; Food-Drug Interactions; Liver; Male; Methylamines; Mice, Inbred C57BL; Oxygenases; Phosphatidylcholines; Polychlorinated Biphenyls; Random Allocation; Up-Regulation

2016
Dietary phosphatidylcholine and risk of all-cause and cardiovascular-specific mortality among US women and men.
    The American journal of clinical nutrition, 2016, Volume: 104, Issue:1

    Topics: Adult; Cardiovascular Diseases; Cohort Studies; Diabetes Complications; Diet; Female; Humans; Male; Methylamines; Middle Aged; Phosphatidylcholines; Risk Factors; United States

2016
Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Aged; Cardiovascular Diseases; Gas Chromatography-Mass Spectrometry; Humans; Intestine, Small; Male; Methylamines; Microbiota; Mixed Function Oxygenases; Oxides; Phosphatidylcholines; Rifamycins; Rifaximin; Risk Factors; Spectrometry, Mass, Electrospray Ionization

2017
Effects of Urea and TMAO on Lipid Self-Assembly under Osmotic Stress Conditions.
    The journal of physical chemistry. B, 2018, 06-28, Volume: 122, Issue:25

    Topics: Calorimetry; Dimyristoylphosphatidylcholine; Magnetic Resonance Spectroscopy; Methylamines; Molecular Dynamics Simulation; Osmotic Pressure; Phosphatidylcholines; Urea; Water

2018
Plasma trimethylamine N-oxide, a gut microbe-generated phosphatidylcholine metabolite, is associated with autism spectrum disorders.
    Neurotoxicology, 2020, Volume: 76

    Topics: Autism Spectrum Disorder; Child; Child, Preschool; Cross-Sectional Studies; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Phosphatidylcholines; Risk Factors; ROC Curve; Severity of Illness Index

2020
Identification of Serum Biomarker in Acute Aortic Dissection by Global and Targeted Metabolomics.
    Annals of vascular surgery, 2020, Volume: 68

    Topics: Acute Disease; Adult; Aortic Aneurysm; Aortic Dissection; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Lipidomics; Male; Mass Spectrometry; Metabolomics; Methylamines; Middle Aged; Phosphatidylcholines; Predictive Value of Tests

2020
Gut microbiota-generated metabolite, trimethylamine-N-oxide, and subclinical myocardial damage: a multicenter study from Thailand.
    Scientific reports, 2021, 07-22, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Atherosclerosis; Cardiovascular Diseases; Case-Control Studies; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Phosphatidylcholines; Risk Assessment; Thailand; Troponin T

2021