phosphatidylcholines has been researched along with tetradecanoylphorbol acetate in 280 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (tetradecanoylphorbol acetate) | Trials (tetradecanoylphorbol acetate) | Recent Studies (post-2010) (tetradecanoylphorbol acetate) |
|---|---|---|---|---|---|
| 32,204 | 443 | 5,593 | 31,050 | 61 | 2,217 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 68 (24.29) | 18.7374 |
| 1990's | 191 (68.21) | 18.2507 |
| 2000's | 18 (6.43) | 29.6817 |
| 2010's | 3 (1.07) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balmain, A; Hecker, E | 1 |
| Dobbs, LG; Mason, RJ | 1 |
| Haagsman, HP; Oosting, RS; Van Bree, L; Van Golde, LM; Van Iwaarden, JF; Verhoef, J | 1 |
| Geilen, CC; Reutter, W; Wieder, T | 2 |
| Akhtar, RA; Wilmoth, TL | 1 |
| Aragonés, MD; Catalán, RE; Hernández, F; Martínez, AM; Miguel, BG | 1 |
| Kiss, Z | 7 |
| Paul, A; Plevin, R; Stewart, A; Wakelam, MJ | 1 |
| Edwards, YS; Hii, CS; Murray, AW | 2 |
| Bressler, JP; Brightman, MW; Tao-Cheng, JH | 1 |
| Kaever, V; Resch, K; Sommermeyer, H | 1 |
| Nitsch, RM; Richardson, UI; Slack, BE; Wurtman, RJ | 1 |
| Daly, JW; Holbrook, PG; Murata, Y; Pannell, LK | 1 |
| Cabot, MC; Daniel, LW; Huang, C; Wykle, RL | 1 |
| Geilen, CC; Reutter, W; Wieder, T; Wieprecht, M | 1 |
| Crichton, CA; Currie, S; Hallam, C; Jackson, CG; Smith, GL; Wakelam, MJ | 1 |
| Gonzalez, OF; Kreisberg, JI; Padilla, RM; Troyer, DA | 1 |
| Boarder, MR; Jones, JA; Owen, PJ; Purkiss, J | 1 |
| Anderson, WB; Crilly, KS; Kiss, Z; Rossi, MA | 1 |
| Cockcroft, S; Geny, B | 1 |
| Lloyd, GS; McNulty, S; Rumsby, MG; Rumsby, RM; Sayner, RM | 1 |
| Hoffman, DR; Snyder, F; Thomas, VL | 1 |
| Chattopadhyay, J; Garamszegi, N; Kiss, Z | 1 |
| Brown, LA; Dubrovin, LC | 1 |
| Cook, SJ; Wakelam, MJ | 3 |
| Rami, J; Rooney, SA; Sasic, SM | 1 |
| Gobran, LI; Griese, M; Rooney, SA | 3 |
| Anthes, JC; Billah, MM; Egan, RW; Krasovsky, J; Siegel, MI | 1 |
| Mohsenin, V; Yoshida, K | 2 |
| Kasuga, M; Konda, Y; Matozaki, T; Matsuda, K; Nagao, M; Nakano, O; Nishisaki, H; Sakamoto, C; Suzuki, T; Wada, K | 1 |
| Jamil, H; Utal, AK; Vance, DE | 1 |
| Borgeat, P; Bourgoin, S; Poubelle, PE | 1 |
| Hsu, YL; Kondratenko, NF; Pandol, SJ; Schoeffield-Payne, MS; Steinbach, JH | 1 |
| Bahrami, LH; Lenhard, LW; Pandol, SJ; Perkins, PS | 1 |
| Agwu, DE; McCall, CE; McPhail, LC | 1 |
| Dunlop, M; Metz, SA | 2 |
| Fain, JN; Pittner, RA | 2 |
| Briscoe, CP; Cook, SJ; Wakelam, MJ | 1 |
| Hosang, M; Pfeilschifter, J | 1 |
| Besemfelder, E; Fürstenberger, G; Hagedorn, H; Jacobi, T; Lehmann, WD; Marks, F; Stephan, M | 1 |
| McNulty, S; Rumsby, M; Sayner, R | 1 |
| Robinson, M; Warne, TR | 1 |
| Jones, GA; Kent, C | 1 |
| Garcia, MC; Mueller, HW; Rosenthal, MD | 1 |
| Alexander, RW; Clark, M; Griendling, KK; Lassègue, B | 1 |
| Baumann, D; Lester, DS | 1 |
| Chen, T; Robinson, M; Warne, TR | 1 |
| Dobbs, LG; Voyno-Yasenetskaya, TA; Williams, MC | 1 |
| Akino, T; Kuroki, Y; Murata, Y; Shiratori, M | 1 |
| Campbell, AK; Rapoport, RM | 1 |
| Chambaz, EM; Daniel, S; Pelosin, JM; Ransac, S; Souvignet, C; Verger, R | 1 |
| Chattopadhyay, J; Kiss, Z; Pettit, GR | 1 |
| Farese, RV; Hoffman, JM; Nair, GP; Standaert, ML | 1 |
| Gonzalez, FA; Heppel, LA; Huang, NN; Wang, DJ | 1 |
| de Widt, J; Hilkmann, H; van Blitterswijk, WJ; van der Bend, RL | 2 |
| Fujimiya, H; Miyata, H; Nakashima, S; Nozawa, Y | 1 |
| Cuatrecasas, P; Hebdon, GM; Irita, K; McConnell, R | 1 |
| Dressler, KA; Kan, CC; Kolesnick, RN | 1 |
| Boeynaems, JM; Lagneau, C; Pirotton, S; Robaye, B | 1 |
| Cornet, ME; Diaz-Laviada, I; Diaz-Meco, MT; Guddal, PH; Johansen, T; Larrodera, P; Lopez-Barahona, M; Moscat, J | 1 |
| Fish, JE; Flynn, JT; Peters, SP; Spannhake, EW; Yoss, EB | 1 |
| Kolesnick, RN | 2 |
| Hemer, MR; Kolesnick, RN | 1 |
| Adams, DO; Hollenbach, PW; Prpic, V; Sebaldt, RJ; Uhing, RJ | 1 |
| Pfeffer, LM; Saltiel, AR; Strulovici, B | 1 |
| Dobbs, LG; Wirtz, HR | 1 |
| Delbart, C; Devred, D; Fruchart, JC; Martin-Nizard, F; Nazih, H | 1 |
| MacNulty, EE; Plevin, R; Wakelam, MJ | 1 |
| Betts, WH; French, JK; Hurst, NP | 1 |
| Gobran, LI; Rooney, SA | 3 |
| Leissner, J; Lindmar, R; Löffelholz, K; Sandmann, J | 1 |
| Clark, KJ; Hii, CS; Kokke, YS; Murray, AW | 1 |
| Feldman, DR; Martin, TW; Michaelis, KC | 1 |
| August, J; Bishop, WR; Pai, JK; Petrin, JM | 1 |
| Carlson, RO; Levitan, IB | 1 |
| Cabot, MC; Huang, CF | 1 |
| Barron, KS; Gilliam, EB; Orson, FM; Patke, CL; Rosenblatt, HM; Shearer, WT | 1 |
| Ansell, GB; Boam, DS; Spanner, SG; Stanworth, DR | 1 |
| Sundler, R; Wijkander, J | 1 |
| Hall, A; Marshall, CJ; Morris, JD; Price, BD | 1 |
| Augert, G; Blackmore, PF; Bocckino, SB; Exton, JH | 1 |
| Chander, A | 1 |
| Kanzaki, T; Morisaki, N; Saito, Y; Yoshida, S | 1 |
| Cabot, MC; Cao, HT; Welsh, CJ; Zhang, ZC | 1 |
| Brown, JH; Goldstein, D; Martinson, EA | 1 |
| Baba, S; Konda, Y; Matozaki, T; Nagao, M; Nakano, O; Nishisaki, H; Sakamoto, C | 1 |
| Hall, A; Morris, JD; Price, BD | 1 |
| Rice, WR; Singleton, FM | 2 |
| Adams, DO; Hollenbach, PW; Prpic, V; Uhing, RJ | 1 |
| Blusztajn, JK; Liscovitch, M; Slack, BE; Wurtman, RJ | 1 |
| Müller-Decker, K | 1 |
| Chap, H; Gelas, P; Record, M; Ribbes, G; Terce, F | 1 |
| Mason, RJ; Sano, K; Voelker, DR | 2 |
| Gilfillan, AM; Rooney, SA | 1 |
| Cabot, MC; Cao, HT; Chabbott, H; Lebowitz, M; Welsh, CJ; Zhang, ZC | 1 |
| Levy, BL; Monaco, ME; Richardson, SB | 1 |
| Anwer, K; Romstedt, K; Wallace, D | 1 |
| Byers, DM; Cook, HW; Palmer, FB; Spence, MW | 1 |
| Camoratto, AM; Grandison, L | 1 |
| Andersson, T; Fällman, M; Stendahl, O | 1 |
| Clark, RA; Sepe, SM | 1 |
| Caldwell, AB; Kreutter, D; Morin, MJ | 1 |
| Gainer, HS; Murray, AW | 1 |
| Deli, E; Kiss, Z; Kuo, JF | 2 |
| Quill, H; Schwartz, RH | 1 |
| Deli, E; Girard, PR; Kiss, Z; Kuo, JF; Pettit, GR | 1 |
| Okimasu, E; Terada, S; Utsumi, K; Yamamoto, M | 1 |
| Cooper, DR; Farese, RV; Nair, GP; Pollet, RJ; Standaert, ML | 1 |
| Daniel, LW; Waite, M; Wykle, RL | 1 |
| de Laat, SW; Feijen, A; Hage, WJ; Snoek, GT; van Rotterdam, W | 1 |
| Cooper, DR; Farese, RV; Pollet, RJ; Standaert, ML | 1 |
| Dobbs, LG; Düzgünes, N; Pian, MS | 1 |
| Cabot, MC; Cao, HT; Chabbott, H; Welsh, CJ | 1 |
| Muir, JG; Murray, AW | 2 |
| Kolesnick, RN; Paley, AE | 1 |
| Glatz, JA; Muir, JG; Murray, AW | 1 |
| Blusztajn, JK; Liscovitch, M; Slack, B; Wurtman, RJ | 1 |
| de Laat, SW; Gitler, C; Rosenberg, I; Snoek, GT | 1 |
| Cossu, G; Eusebi, F; Giacomoni, D; Molinaro, M; Senni, MI | 1 |
| Blusztajn, JK; Freese, A; Liscovitch, M; Wurtman, RJ | 1 |
| Caratsch, CG; Eusebi, F; Grassi, F; Molinaro, M | 1 |
| Cohen, A; Mellors, A; Stalmach, ME | 1 |
| Hill, SA; McMurray, WC; Sanwal, BD | 1 |
| Mueller, GC; Wertz, PW | 1 |
| Best, L; Hubinont, CJ; Malaisse, WJ; Sener, A | 1 |
| Friedkin, M; Warden, CH | 1 |
| Dawson, G; Golomb, HM; Lockney, MW | 1 |
| Fjose, A; Lillehaug, JR; Pryme, IF | 1 |
| Defrise-Quertain, F; Deleers, M; Malaisse, WJ; Ruysschaert, JM | 1 |
| Castagna, M; Madelmont, G; Ter-Minassian-Saraga, L; Tran, PL | 1 |
| Cassileth, PA; Cooper, RA; Suholet, D | 1 |
| Guy, GR; Murray, AW | 1 |
| Grove, RI; Schimmel, SD | 1 |
| Cabot, MC; Callaham, MF; Huberman, E; Welsh, CJ | 1 |
| Estensen, RD; Plagemann, PG | 1 |
| Hirai, K; Koike, T; Mizutani, T; Morita, Y; Nozawa, Y | 1 |
| Mosior, M; Newton, AC | 1 |
| Li, Q; Yokoyama, S | 1 |
| Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A; Watanabe, Y | 1 |
| Jisaka, M; Takeuchi, J; Takinami, K; Yokota, K | 1 |
| Kiss, Z; Tomono, M | 1 |
| Heung, YM; Postle, AD | 3 |
| Purkiss, JR | 1 |
| Baird, B; Chang, EY; Holowka, D; Zheng, Y | 1 |
| Baudet, C; Brachet, P; Galve-Roperh, I; Laviada, ID; Naveilhan, P | 1 |
| Chap, H; Planat, V; Record, M; Ribbes, G; Tercé, F; Tronchère, H | 1 |
| Halstead, J; Ignotz, RA; Kemp, K | 1 |
| Benito, E; Bosch, MA; Romero, C | 1 |
| Breu, J; Eldar, H; Livneh, E; Slack, BE; Wurtman, RJ | 1 |
| Chander, A; Sen, N; Spitzer, AR; Wu, AM | 1 |
| Berthezene, F; Bourdillon, MC; Dusserre, E; Pulcini, T | 1 |
| Brown, JH; Goldstein, D; Kennedy, E; Nieto, M | 1 |
| Anderson, WB; Kiss, Z; Tomono, M | 1 |
| Ito, Y; Kotoyori, J; Kozawa, O; Oiso, Y; Suzuki, A; Tokuda, H; Watanabe, Y | 1 |
| Gobran, LI; Lu, Z; Rooney, SA; Xu, ZX | 1 |
| Arndt, D; Geilen, CC; Haase, A; Reutter, W; Wieder, T; Zeisig, R | 1 |
| Anderson, WH; Kiss, Z | 2 |
| Hathout, Y; Maume, BF; Maume, G | 1 |
| Baldi, E; Kester, M; Musial, A | 1 |
| Chinoy, MR; Dodia, C; Fisher, AB | 1 |
| Boland, R; de Boland, AR; Morelli, S | 1 |
| Scott, JE | 1 |
| Alexandropoulos, K; Foster, DA; Jiang, H; Song, J | 1 |
| Kanzaki, T; Morisaki, N; Saito, Y; Ueda, S; Yokote, K; Yoshida, S; Zenibayashi, M | 1 |
| Exton, JH; Ha, KS | 2 |
| Gobran, LI; Phelps, DS; Rooney, SA; Umstead, TM | 1 |
| Belury, MA; Fischer, SM; Locniskar, M | 1 |
| Cox, KJ; Ho, C; Kelly, MB; Lombardi, JV; Rubin, E; Slater, SJ; Stubbs, CD | 1 |
| Belury, MA; Fischer, SM; Lee, WY; Lo, HH; Locniskar, MF | 1 |
| Chap, H; Record, M; Tercé, F; Tronchère, H | 1 |
| Garamszegi, N; Kiss, Z | 1 |
| Devary, Y; DiDonato, JA; Karin, M; Rosette, C | 1 |
| Hannun, YA; Hong, JS; Hudson, PM; McMillian, MK; Tuominen, RK; Werner, MH; Ye, H | 1 |
| Barinov, VV; Bassalyk, LS; Krasil'nikov, MA; Kuzmina, ZV; Letyagin, VP; Shatskaya, VA | 1 |
| Daniel, LW; Greene, D; Huang, C; Smitherman, PK; Strum, JC; Wykle, RL | 1 |
| Gupta, AG; Hirakata, A; Proia, AD | 1 |
| Castagna, M; Da Silva, C; Fan, XT; Huang, XP | 1 |
| Jackowski, S; Rock, CO; Tessner, TG; Xu, XX | 1 |
| Pyne, NJ; Pyne, S | 1 |
| Cabot, MC; Huang, C; Wykle, RL | 1 |
| Campenot, RB; Posse de Chaves, E; Vance, DE; Vance, JE | 1 |
| Kozawa, O; Oiso, Y; Suzuki, A | 1 |
| Balogh, A; Csuka, O; Kéri, G; Teplán, I | 1 |
| Bellido, ML; Lucas, M; Pedrera, C; Sänchez-Margalet, V | 1 |
| Byers, DM; Cook, HW; Morash, SC; Ridgway, DN; Rose, SD | 1 |
| Kozawa, O; Oiso, Y; Saito, H; Shinoda, J; Suzuki, A; Watanabe, Y | 1 |
| Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A | 1 |
| Byers, DM; Cook, HW; Morash, SC; Sproull, SA | 1 |
| Gautero, H; Geny, B; Lecomte, MC; Lukowski, S; Marin, P; Mira, JP; Russo-Marie, F | 1 |
| Byers, DM; Cook, HW; Mandla, SG; Ridgway, ND | 1 |
| Kato, K; Kozawa, O; Oiso, Y; Suzuki, A | 1 |
| Isoherranen, K; Laihia, J; Leino, L; Punnonen, K | 1 |
| Bernhard, W; Piller, M; Schulte, H; Sewing, KF | 1 |
| Igata, A; Imamura, Y; Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A; Tokuda, H; Watanabe-Tomita, Y | 1 |
| el Bawab, S; Goncalves, A; Lagarde, M; Macovschi, O; Némoz, G; Prigent, AF; Thevenon, C | 1 |
| Dingley, AJ; King, GF; King, NJ; Veale, MF | 1 |
| Capito, K; Hansen, SE; Thams, P | 1 |
| Cordier, J; Desagher, S; Glowinski, J; Tencé, M | 1 |
| Allan, D; Decker, C; Miro Obradors, MJ; Sillence, DJ | 1 |
| Tóth, M | 1 |
| Bellemare, F; Rocheleau, H | 1 |
| Dong, Z; Guyer, B; Kiss, Z | 1 |
| Edwards, CM; Geister, U; Lowe, KC; Meinert, H; Reuter, P; Röhlke, W | 1 |
| Li, HL; Liu, L; Tao, JQ; Zimmerman, UJ | 1 |
| Julien, M; Millot, C; Tocanne, JF; Tournier, JF | 1 |
| Ito, T; Kambayashi, Y; Nakano, M; Watanabe, K; Yamamoto, Y | 1 |
| Fischer, SM; Li-Stiles, B; Lo, HH | 1 |
| King, GF; King, NJ; Roberts, NJ; Veale, MF | 1 |
| Anderson, WH; Crilly, KS; Kiss, Z | 2 |
| Exton, JH; Guillemain, I | 1 |
| Assmann, G; Nofer, JR; Seedorf, U; Tepel, M; Walter, M; Zidek, W | 1 |
| Byers, DM; Cook, HW; Ridgway, ND | 1 |
| Capito, K; Hansen, SE; Hedeskov, CJ; Thams, P | 1 |
| Benito, E; Blazquez, E; Bosch, MA | 1 |
| Honda, T; Koizumi, T; Koyama, S; Kubo, K; Miyahara, T; Sekiguchi, M; Shibamoto, T; Wang, HG | 1 |
| Byers, DM; Cook, HW; Morash, SC; Ridgway, ND; Rosé, SD | 1 |
| Pettitt, TR; Wakelam, MJ | 1 |
| Byers, DM; Cook, HW; Logan, HE; Ridgway, ND | 1 |
| Bitar, KN; Hajra, A; Sbrissa, D | 1 |
| Liu, L | 2 |
| Fujieda, M; Ide, H; Ishikawa, C; Kaneki, H; Mizuochi, S; Yokozawa, J | 1 |
| Alessi, DR; Cohen, P; Le Good, JA; Parekh, DB; Parker, PJ; Ziegler, WH | 1 |
| Edwards, YS; Murray, AW; Nicholas, TE; Power, JH; Sutherland, LM | 1 |
| Mookerjea, S; Ratnam, S | 1 |
| Bruland, O; Holmsen, H; Lillehaug, JR; Thorsen, VA | 1 |
| Gilbert, JJ; Harnett, MM; Pettitt, TR; Reid, SD; Seatter, SD; Wakelam, MJ | 1 |
| Anderson, WB; Kiss, Z; Lehel, C; Olàh, Z; Petrovics, G | 1 |
| Baburina, I; Jackowski, S | 1 |
| Daniel, LW; Ghosh, S; Sciorra, VA | 1 |
| Li, HL; Liu, L; Malek, SK; Zimmerman, UJ | 1 |
| Chander, A; Sen, N; Spitzer, AR; Wadsworth, S | 1 |
| Bandyopadhyay, R; Basu, MK | 1 |
| Nikia, E; Noguchia, N; Okimotoa, Y; Watanabea, A; Yamashitab, T | 1 |
| Bjørndal, B; Bruland, O; Fukami, MH; Holmsen, H; Lillehaug, JR; Nolan, G; Thorsen, VA | 1 |
| Antony, P; Freysz, L; Kanfer, JN | 1 |
| Claro, E; Ramos, B; Salido, G; Sarri, E | 1 |
| Grafton, J; Hutson, E; Kidd, D; Kobayashi, M; McNulty, S; Rumsby, M | 1 |
| Tou, J; Urbizo, C | 1 |
| Isohama, Y; Kai, H; Kanemaru, M; Miyata, T; Takahama, K | 1 |
| Atruz, OM; Chuchalin, AG; Selishcheva, AA; Skrjabin, GA; Sorokoumova, GM; Vasilenko, IA | 1 |
| Clay, K; Dinauer, M; Hiran, T; Johnson, C; Travers, J | 1 |
| Ishii, S; Izumi, T; Ohshima, N; Shimizu, T | 1 |
| Eriksson, E; Hellstrand, M; Nilsson, CL | 1 |
| Ito, J; Nagayasu, Y; Ueno, S; Yokoyama, S | 1 |
| Jerlich, A; Pitt, AR; Schaur, RJ; Spickett, CM | 1 |
| Bleijerveld, OB; Helms, JB; Houweling, M; Klein, W; Vaandrager, AB | 1 |
| Callender, DL; Chander, A; Cohen, JC; Dlugosz, MA; Gad, A; Hudak, J; Killeen, E; Larson, JE | 1 |
| Barter, PJ; Di Bartolo, B; Dusting, GJ; Jiang, F; Peshavariya, H; Rye, KA | 1 |
| Wang, HL; Wang, LC; Wei, JW | 1 |
| Baskin, JM; Bumpus, TW; Liang, FJ | 1 |
| Buso, MAOV; Díez-Sales, O; Mir-Palomo, S; Nácher, A; Pleguezuelos-Villa, M; Sauri, AR | 1 |
1 review(s) available for phosphatidylcholines and tetradecanoylphorbol acetate
| Article | Year |
|---|---|
Phospholipase D, tumor promoters, proliferation and prostaglandins.
Topics: Animals; Carcinogens; Cell Division; Cell Line; Enzyme Activation; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate | 1999 |
1 trial(s) available for phosphatidylcholines and tetradecanoylphorbol acetate
| Article | Year |
|---|---|
Arachidonic acid metabolism in normal human alveolar macrophages: stimulus specificity for mediator release and phospholipid metabolism, and pharmacologic modulation in vitro and in vivo.
Topics: Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Dexamethasone; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Macrophage Activation; Macrophages; Phosphatidylcholines; Phosphatidylinositols; Pulmonary Alveoli; Radioimmunoassay; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1990 |
278 other study(ies) available for phosphatidylcholines and tetradecanoylphorbol acetate
| Article | Year |
|---|---|
On the biochemical mechanism of tumorigenesis in mouse skin. VII. The effects of tumor promoters on 3H-choline and 3H-glycerol incorporation into mouse epidermal phosphatidylcholine in relation to their effects on 3H-thymidine incorporation into DNA.
Topics: Animals; Choline; DNA, Neoplasm; Female; Glycerol; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Phosphatidylcholines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Stimulation of secretion of disaturated phosphatidylcholine from isolated alveolar type II cells by 12-O-tetradecanoyl-13-phorbol acetate.
Topics: Animals; Cells, Cultured; Colchicine; Cold Temperature; Dogs; In Vitro Techniques; L-Lactate Dehydrogenase; Phorbols; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Vinblastine | 1978 |
Exposure of surfactant protein A to ozone in vitro and in vivo impairs its interactions with alveolar cells.
Topics: Animals; Bronchoalveolar Lavage Fluid; Drug Interactions; Macrophages; Ozone; Phagocytosis; Phosphatidylcholines; Proteolipids; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate; Trypan Blue | 1992 |
Hexadecylphosphocholine inhibits translocation of CTP:choline-phosphate cytidylyltransferase in Madin-Darby canine kidney cells.
Topics: Animals; Biological Transport; Cells, Cultured; Choline; Choline-Phosphate Cytidylyltransferase; Diglycerides; Dogs; Kidney; Nucleotidyltransferases; Phosphatidylcholines; Phosphorylcholine; Tetradecanoylphorbol Acetate | 1992 |
Phorbol esters inhibit ionomycin-induced hydrolysis of phosphoinositides and phosphatidylcholine in bovine corneal epithelial cells.
Topics: Animals; Cattle; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cornea; Enzyme Activation; Epithelium; Hydrolysis; Ionomycin; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Phorbol esters stimulate phosphoinositide phosphorylation and phosphatidylcholine metabolism in brain microvessels.
Topics: Animals; Blood-Brain Barrier; Brain; Diglycerides; In Vitro Techniques; Male; Microcirculation; Phosphatidylcholines; Phosphatidylinositols; Phosphorylation; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1992 |
The protein phosphatase inhibitor, okadaic acid, potentiates the stimulatory effect of phorbol ester on phosphatidylcholine synthesis, but not on phospholipid hydrolysis, in fibroblasts.
Topics: 3T3 Cells; Animals; Choline; Drug Synergism; Ethers, Cyclic; Fibroblasts; Hydrolysis; Mice; Okadaic Acid; Phosphatidylcholines; Phospholipids; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate | 1992 |
Vasopressin-stimulated [3H]-inositol phosphate and [3H]-phosphatidylbutanol accumulation in A10 vascular smooth muscle cells.
Topics: Animals; Arginine Vasopressin; Glycerophospholipids; Hydrolysis; Indoles; Inositol 1,4,5-Trisphosphate; Mice; Muscle, Smooth, Vascular; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1992 |
Basal and phorbol-ester-stimulated turnover of phosphatidylcholine in HeLa cells involve different pathways.
Topics: Cell Membrane; Diacylglycerol Kinase; Diglycerides; HeLa Cells; Humans; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phosphotransferases; Platelet Activating Factor; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases | 1992 |
Astroglial membrane structure is affected by agents that raise cyclic AMP and by phosphatidylcholine phospholipase C.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Freeze Fracturing; Glioma; Guinea Pigs; Immunohistochemistry; Isoproterenol; Lectins; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Protein Kinases; Rats; Retina; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1992 |
Cleavage of phosphatidylcholine: an additional mechanism for stimulation of macrophage eicosanoid synthesis?
Topics: Animals; Choline; Diglycerides; Eicosanoids; Enzyme Activation; Kinetics; Macrophages; Mice; Mice, Inbred DBA; Peritoneal Cavity; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Cooperative effects of ethanol and protein kinase C activators on phospholipase-D-mediated hydrolysis of phosphatidylethanolamine in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Bombesin; Dose-Response Relationship, Drug; Enzyme Activation; Ethanol; Mice; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line.
Topics: Acetylcholine; Choline; Diglycerides; Humans; Nervous System Neoplasms; Neuroblastoma; Osmolar Concentration; Parasympathetic Nervous System; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Molecular species analysis of a product of phospholipase D activation. Phosphatidylethanol is formed from phosphatidylcholine in phorbol ester- and bradykinin-stimulated PC12 cells.
Topics: Animals; Bradykinin; Glycerophospholipids; Kinetics; Mass Spectrometry; Oleic Acid; Oleic Acids; PC12 Cells; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipids; Tetradecanoylphorbol Acetate | 1992 |
Identification of phosphatidylcholine-selective and phosphatidylinositol-selective phospholipases D in Madin-Darby canine kidney cells.
Topics: Animals; Bradykinin; Calcium; Cell Fractionation; Cell Line; Detergents; Dogs; Isoenzymes; Kidney; Kinetics; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Substrate Specificity; Tetradecanoylphorbol Acetate | 1992 |
A selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-bromocinnamyl(amino)ethyl]-5-isoquinolinesulfonamide (H-89), inhibits phosphatidylcholine biosynthesis in HeLa cells.
Topics: Colforsin; HeLa Cells; Humans; Isoquinolines; Kinetics; Phosphatidylcholines; Protein Kinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate | 1992 |
Bombesin stimulates the rapid activation of phospholipase A2-catalyzed phosphatidylcholine hydrolysis in Swiss 3T3 cells.
Topics: 3T3 Cells; Alkaloids; Animals; Arachidonic Acid; Bombesin; Calcium; Calcium-Transporting ATPases; Carbon Radioisotopes; Dose-Response Relationship, Drug; Enzyme Activation; Hydrolysis; Kinetics; Lysophosphatidylcholines; Mice; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phospholipids; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Vasopressin and phorbol ester-stimulated phosphatidylcholine metabolism in mesangial cells.
Topics: Animals; Chromatography, Thin Layer; Culture Media; Glomerular Mesangium; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Vasopressins | 1992 |
Stimulation of phosphatidic acid synthesis in bovine aortic endothelial cells in response to activation of P2-purinergic receptors.
Topics: Animals; Aorta; Calcimycin; Calcium; Cattle; Endothelium, Vascular; Enzyme Activation; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Selective inhibition by 4-hydroxynonenal of sphingosine-stimulated phospholipase D in NIH 3T3 cells.
Topics: 3T3 Cells; Aldehydes; Animals; Enzyme Activation; Hydrolysis; Mice; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Sphingosine; Tetradecanoylphorbol Acetate | 1992 |
Synergistic activation of phospholipase D by protein kinase C- and G-protein-mediated pathways in streptolysin O-permeabilized HL60 cells.
Topics: Adenosine Triphosphate; Alkaloids; Bacterial Proteins; Cell Line; Cell Membrane Permeability; Drug Synergism; Enzyme Activation; Glycerophospholipids; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Neomycin; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Staurosporine; Streptolysins; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Ethanolamine is released from glial cells in primary culture on stimulation with foetal calf serum and phorbol ester.
Topics: Animals; Astrocytes; Cattle; Cells, Cultured; Ethanolamines; Fetal Blood; Neuroglia; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1992 |
Inhibition of cellular transport systems by alkyl phospholipid analogs in HL-60 human leukemia cells.
Topics: Antineoplastic Agents; Biological Transport; Cell Line; Cell Survival; Choline; Humans; Leukemia, Promyelocytic, Acute; Monosaccharide Transport Proteins; Phosphatidylcholines; Phospholipid Ethers; Tetradecanoylphorbol Acetate | 1992 |
1,2-Diacylglycerol does not mediate the stimulatory effect of phorbol 12-myristate 13-acetate on phosphatidylcholine synthesis in NIH 3T3 fibroblasts.
Topics: Cell Line; Diglycerides; Ethanol; Fibroblasts; HeLa Cells; Hot Temperature; Humans; Hydrolysis; Phosphatidylcholines; Tetradecanoylphorbol Acetate | 1992 |
Stimulation of phosphatidylcholine hydrolysis in type II alveolar epithelial cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Choline; Down-Regulation; Epithelial Cells; Epithelium; Hydrolysis; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Epidermal growth factor increases sn-1,2-diacylglycerol levels and activates phospholipase D-catalysed phosphatidylcholine breakdown in Swiss 3T3 cells in the absence of inositol-lipid hydrolysis.
Topics: 3T3 Cells; Animals; Bombesin; Catalysis; Diglycerides; Enzyme Activation; Epidermal Growth Factor; Glycerophospholipids; Indoles; Inositol Phosphates; Mice; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
Enhanced fatty acid biosynthesis and normal surfactant secretion in hypertrophic rat type II cells.
Topics: Acetates; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; ATP Citrate (pro-S)-Lyase; Cells, Cultured; Choline; Choline-Phosphate Cytidylyltransferase; Diglycerides; DNA; Fatty Acids; Hypertrophy; Ionomycin; Kinetics; Lung; Male; Nucleotidyltransferases; Phosphatidylcholines; Phospholipids; Proteins; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Reference Values; Silicon Dioxide; Terbutaline; Tetradecanoylphorbol Acetate | 1991 |
ATP-stimulated inositol phospholipid metabolism and surfactant secretion in rat type II pneumocytes.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cells, Cultured; Chlorides; Choline; Diglycerides; Inositol; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Lung; Male; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Sequential degradation of choline phosphoglycerides by phospholipase D and phosphatidate phosphohydrolase in dibutyryl cAMP-differentiated U937 cells.
Topics: Animals; Bucladesine; Cell Differentiation; Cell Line; Cytochalasin B; Hydrolysis; Kinetics; Leukocytes, Mononuclear; Phosphatidate Phosphatase; Phosphatidylcholines; Phospholipase D; Phosphorylation; Rats; Tetradecanoylphorbol Acetate | 1991 |
Unsaturated phosphatidylcholines inhibit superoxide production in human neutrophils.
Topics: Analysis of Variance; Cell Fractionation; Diglycerides; Enzyme Activation; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Cholecystokinin inhibits phosphatidylcholine synthesis via a Ca(2+)-calmodulin-dependent pathway in isolated rat pancreatic acini. A possible mechanism for diacylglycerol accumulation.
Topics: Alkaloids; Animals; Bombesin; Bucladesine; Calcimycin; Calcium; Calmodulin; Carbachol; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Diglycerides; In Vitro Techniques; Kinetics; Male; Nucleotidyltransferases; Pancreas; Phosphatidylcholines; Protein Kinase C; Rats; Rats, Inbred Strains; Secretin; Sincalide; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tritium | 1991 |
Diacylglycerol signals the translocation of CTP:choline-phosphate cytidylyltransferase in HeLa cells treated with 12-O-tetradecanoylphorbol-13-acetate.
Topics: Cell Membrane Permeability; Choline-Phosphate Cytidylyltransferase; Digitonin; Diglycerides; HeLa Cells; Humans; Kinetics; Microsomes; Nucleotidyltransferases; Phosphatidylcholines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) primes human neutrophils for enhanced phosphatidylcholine breakdown by phospholipase D.
Topics: Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Phospholipase D; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Up-Regulation | 1991 |
Dual pathways for agonist-stimulated arachidonic acid release in pancreatic acini: roles in secretion.
Topics: Amylases; Animals; Arachidonic Acids; Cyclohexanones; Diglycerides; Fatty Acids; Guinea Pigs; In Vitro Techniques; Kinetics; Lipoprotein Lipase; Lysophosphatidylcholines; Pancreas; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Sincalide; Tetradecanoylphorbol Acetate | 1991 |
Intracellular mechanisms involved in short-term regulation of net protein synthesis in pancreatic acini.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amylases; Animals; Calcimycin; Carbachol; DNA Probes; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzymes; Isoquinolines; Lipase; Nucleic Acid Hybridization; Pancreas; Pancreatic Elastase; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Regulation of phospholipase D-induced hydrolysis of choline-containing phosphoglycerides by cyclic AMP in human neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; Cyclic AMP; Dinoprostone; Humans; Hydrolysis; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1991 |
Activation of phospholipase D by glyceraldehyde in isolated islet cells follows protein kinase C activation.
Topics: Animals; Cells, Cultured; Enzyme Activation; Glyceraldehyde; Islets of Langerhans; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1992 |
Ethanol is a potent stimulator of phosphatidylcholine breakdown in cultured rat hepatocytes.
Topics: Adenosine Triphosphate; Alcohols; Animals; Calcimycin; Cells, Cultured; Choline; Ethanol; Inositol Phosphates; Liver; Norepinephrine; Phosphatidylcholines; Phospholipases; Phosphorylcholine; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1992 |
The regulation of phospholipase D activity and its role in sn-1,2-diradylglycerol formation in bombesin- and phorbol 12-myristate 13-acetate-stimulated Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Bombesin; Butanols; Diglycerides; Inositol Phosphates; Mice; Phosphatidylcholines; Phospholipase D; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1991 |
Effects of homo- and heterodimeric isoforms of PDGF on signalling events in rat renal mesangial cells.
Topics: Animals; Cell Division; Cells, Cultured; Dinoprostone; Glomerular Mesangium; Inositol Phosphates; Kinetics; Neutralization Tests; Pertussis Toxin; Phosphatidylcholines; Platelet-Derived Growth Factor; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Activation of membrane protein kinase C by glucagon and Ca(2+)-mobilizing hormones in cultured rat hepatocytes. Role of phosphatidylinositol and phosphatidylcholine hydrolysis.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Calcimycin; Cell Membrane; Cells, Cultured; Enzyme Activation; Glucagon; Hydrolysis; Inositol Phosphates; Kinetics; Liver; Myristic Acid; Myristic Acids; Norepinephrine; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1991 |
Characterization of an 8-lipoxygenase activity induced by the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate in mouse skin in vivo.
Topics: Aging; Animals; Arachidonate Lipoxygenases; Catalysis; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Enzyme Activation; Female; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotrienes; Liposomes; Mice; Phosphatidylcholines; Skin; Tetradecanoylphorbol Acetate | 1991 |
Ethanolamine as well as choline is released to the external medium on phorbol ester and foetal calf serum stimulation of glial cells in primary culture.
Topics: Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultured; Choline; Culture Media; Ethanolamine; Ethanolamines; Kinetics; Neuroglia; Oligodendroglia; Phosphatidylcholines; Rats; Tetradecanoylphorbol Acetate | 1991 |
Sources of diradylglycerols generated during cell growth and phorbol ester stimulation in Madin-Darby canine kidney cells.
Topics: Animals; Cell Division; Cells, Cultured; Chromatography, High Pressure Liquid; Diglycerides; Dogs; Hydrolysis; Kidney; Phosphatidylcholines; Tetradecanoylphorbol Acetate | 1991 |
The role of protein kinase C in the stimulation of phosphatidylcholine synthesis by phospholipase C.
Topics: Animals; Biological Transport; Cell Line; Choline; Cricetinae; Cricetulus; Cytosol; Diglycerides; Female; Kinetics; Ovary; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1991 |
C20 polyunsaturated fatty acids and phorbol myristate acetate enhance agonist-stimulated synthesis of 1-radyl-2-acetyl-sn-glycero-3-phosphocholine in vascular endothelial cells.
Topics: Acetates; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cattle; Endothelium, Vascular; Fatty Acids, Unsaturated; Kinetics; Phosphatidylcholines; Sphingosine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tritium | 1991 |
Angiotensin II-induced phosphatidylcholine hydrolysis in cultured vascular smooth-muscle cells. Regulation and localization.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arsenicals; Cells, Cultured; Choline; Egtazic Acid; Hydrolysis; Kinetics; Male; Muscle, Smooth, Vascular; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1991 |
Action of organic solvents on protein kinase C.
Topics: Animals; Binding, Competitive; Diglycerides; Enzyme Activation; Histones; Lipid Bilayers; Male; Membrane Fluidity; Membranes, Artificial; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phosphatidylserines; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred Strains; Solvents; Tetradecanoylphorbol Acetate | 1991 |
IL-3-induced generation of alkylacylglycerol and diacylglycerol in an IL-3-dependent cell line.
Topics: Acylation; Animals; Cell Line; Diglycerides; Immunoglobulin E; Interleukin-3; Mice; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Regulation of ATP-dependent surfactant secretion and activation of second-messenger systems in alveolar type II cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calmodulin; Cells, Cultured; Enzyme Activation; Inositol Phosphates; Osmolar Concentration; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Second Messenger Systems; Sulfonamides; Tetradecanoylphorbol Acetate | 1991 |
Surfactant protein D (SP-D) counteracts the inhibitory effect of surfactant protein A (SP-A) on phospholipid secretion by alveolar type II cells. Interaction of native SP-D with SP-A.
Topics: Animals; Binding, Competitive; Blotting, Western; Bronchoalveolar Lavage Fluid; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Methylmannosides; Phosphatidylcholines; Phospholipids; Proteolipids; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1991 |
Norepinephrine-induced phosphatidylcholine hydrolysis in intact rat aorta.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Hydrolysis; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phosphatidylcholines; Phospholipase D; Phosphorylcholine; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1991 |
Phorbol ester-stimulated hydrolysis of phosphatidylcholine and phosphatidylethanolamine by phospholipase D in HeLa cells. Evidence that the basal turnover of phosphoglycerides does not involve phospholipase D.
Topics: Choline; Fatty Alcohols; HeLa Cells; Humans; Hydrolysis; Lysophosphatidylcholines; Palmitic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Propranolol; Tetradecanoylphorbol Acetate | 1991 |
Activation of protein kinase C in lipid monolayers.
Topics: Animals; Brain; Diglycerides; Enzyme Activation; Liposomes; Phosphatidylcholines; Phosphatidylserines; Pressure; Protein Kinase C; Rats; Surface Properties; Tetradecanoylphorbol Acetate | 1991 |
Stimulation of phosphatidylcholine synthesis by activators of protein kinase C is dissociable from increased phospholipid hydrolysis.
Topics: Animals; Bryostatins; Cells, Cultured; Enzyme Activation; Fibroblasts; Hydrolysis; Ionomycin; Lactones; Leukemia, Experimental; Macrolides; Phosphatidylcholines; Phospholipids; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1991 |
Differential effects of pertussis toxin on insulin-stimulated phosphatidylcholine hydrolysis and glycerolipid synthesis de novo. Studies in BC3H-1 myocytes and rat adipocytes.
Topics: Adipose Tissue; Animals; Anti-Bacterial Agents; Cell Line; Cells, Cultured; Hydrolysis; Insulin; Kinetics; Male; Muscles; Myristic Acid; Myristic Acids; Pertussis Toxin; Phosphatidic Acids; Phosphatidylcholines; Pyrimidine Nucleosides; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Hydrolysis of phosphatidylcholine by phospholipase D is a common response to mitogens which stimulate inositol lipid hydrolysis in Swiss 3T3 fibroblasts.
Topics: Arginine Vasopressin; Bombesin; Cell Line; Choline; Dinoprost; Enzyme Activation; Fibroblasts; Glycerophospholipids; Hydrolysis; Inositol; Inositol Phosphates; Kinetics; Mitogens; Palmitic Acid; Palmitic Acids; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1991 |
Multiple signal transduction pathways lead to extracellular ATP-stimulated mitogenesis in mammalian cells: I. Involvement of protein kinase C-dependent and -independent pathways.
Topics: Adenosine Triphosphate; Animals; Bombesin; Carcinoma, Squamous Cell; Cell Line; Diglycerides; DNA; Down-Regulation; Drug Synergism; Enzyme Activation; Fibroblasts; Glycerides; Humans; Mice; Mitosis; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylcholines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Vasopressins; Virulence Factors, Bordetella | 1991 |
Phospholipid metabolism in bradykinin-stimulated human fibroblasts. I. Biphasic formation of diacylglycerol from phosphatidylinositol and phosphatidylcholine, controlled by protein kinase C.
Topics: Alkaloids; Bradykinin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diglycerides; Down-Regulation; Fibroblasts; Glyceryl Ethers; Humans; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Phospholipid metabolism in bradykinin-stimulated human fibroblasts. II. Phosphatidylcholine breakdown by phospholipases C and D; involvement of protein kinase C.
Topics: Bradykinin; Choline; Diglycerides; Down-Regulation; Ethanol; Fibroblasts; Glyceryl Ethers; Humans; Hydrolysis; Ionomycin; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1991 |
Antigen-induced biphasic diacylglycerol formation in RBL-2H3 cells: the late sustained phase due to phosphatidylcholine hydrolysis is dependent on protein kinase C.
Topics: Animals; Antigens; Calcimycin; Cell Line; Choline; Diglycerides; Hydrolysis; Kinetics; Leukemia, Basophilic, Acute; Myristic Acid; Myristic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1991 |
Difference between the calcium- and the phorbol ester-induced association of protein kinase C with phospholipid membrane.
Topics: Animals; Brain; Calcium; Diglycerides; Drug Synergism; Liposomes; Magnesium; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Potassium Chloride; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1991 |
Sphingomyelin synthesis is involved in adherence during macrophage differentiation of HL-60 cells.
Topics: Cell Adhesion; Cell Line; Ceramides; Macrophages; Phosphatidylcholines; Phospholipases; Phosphorylcholine; Sphingomyelins; Sphingosine; Tetradecanoylphorbol Acetate | 1991 |
Adenine nucleotides modulate phosphatidylcholine metabolism in aortic endothelial cells.
Topics: Adenine Nucleotides; Animals; Aorta; Bradykinin; Calcimycin; Calcium; Cattle; Cholera Toxin; Choline; Down-Regulation; Endothelium, Vascular; Extracellular Space; GTP-Binding Proteins; In Vitro Techniques; Pertussis Toxin; Phosphatidylcholines; Protein Kinase C; Receptors, Purinergic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesis.
Topics: Animals; Bacillus cereus; Cells, Cultured; DNA; DNA Replication; Drug Synergism; Hydrolysis; Insulin; Kinetics; Mice; Phosphatidylcholines; Platelet-Derived Growth Factor; Tetradecanoylphorbol Acetate; Thymidine; Type C Phospholipases | 1990 |
1,2-Diacylglycerols overcome cyclic AMP-mediated inhibition of phosphatidylcholine synthesis in GH3 pituitary cells.
Topics: Bucladesine; Cell Line; Cholera Toxin; Cyclic AMP; Diglycerides; Glycerides; Phosphates; Phosphatidylcholines; Pituitary Gland; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1990 |
Physiologic 1,2-diacylglycerol levels induce protein kinase C-independent translocation of a regulatory enzyme.
Topics: Biological Transport; Cell Line; Cell Membrane; Choline; Choline-Phosphate Cytidylyltransferase; Cytosol; Diglycerides; Down-Regulation; Glycerides; Microsomes; Nucleotidyltransferases; Phosphates; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
IFN-gamma potentiates the accumulation of diacylglycerol in murine macrophages.
Topics: Animals; Calcium; Cells, Cultured; Diglycerides; Drug Synergism; Glycerides; In Vitro Techniques; Inositol Phosphates; Interferon-gamma; Ionomycin; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phosphatidylcholines; Phosphatidylinositols; Platelet Activating Factor; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1990 |
Interferon-alpha selectively activates the beta isoform of protein kinase C through phosphatidylcholine hydrolysis.
Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cytosol; Diglycerides; Enzyme Activation; HeLa Cells; Humans; Hydrolysis; Interferon Type I; Isoenzymes; Kinetics; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Protein Kinase C; Receptors, Drug; Recombinant Proteins; Tetradecanoylphorbol Acetate; Vesicular stomatitis Indiana virus | 1990 |
Calcium mobilization and exocytosis after one mechanical stretch of lung epithelial cells.
Topics: Animals; Biomechanical Phenomena; Calcium; Cells, Cultured; Cyclic AMP; Epithelium; Exocytosis; Kinetics; Phosphatidylcholines; Proteolipids; Pulmonary Alveoli; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Surface Properties; Tetradecanoylphorbol Acetate | 1990 |
Phosphatidylcholine breakdown in HDL3 stimulated platelets.
Topics: Blood Platelets; Diacylglycerol Kinase; Diglycerides; Humans; In Vitro Techniques; Lipoproteins, HDL; Lipoproteins, HDL3; Phosphatidic Acids; Phosphatidylcholines; Phosphotransferases; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1990 |
Stimulation of the hydrolysis of phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine by endothelin, a complete mitogen for Rat-1 fibroblasts.
Topics: Animals; Cell Line; Choline; Endothelins; Fibroblasts; Hydrolysis; Inositol Phosphates; Kinetics; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Tetradecanoylphorbol Acetate | 1990 |
Phorbol 12-myristate 13-acetate, A23187 and L-adrenaline inhibit phospholipid methylation in human monocytes and lymphocytes. Inhibition is independent of oxyradical production and phospholipid hydrolysis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Epinephrine; Free Radicals; Humans; Hydrolysis; Isoquinolines; Lymphocytes; Methylation; Monocytes; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Piperazines; Protein Kinase Inhibitors; S-Adenosylmethionine; Sodium Fluoride; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Adenosine A1 receptor-mediated inhibition of surfactant secretion in rat type II pneumocytes.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Choline; Colforsin; Diglycerides; Ionomycin; Kinetics; Lung; Male; Phosphatidylcholines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Terbutaline; Tetradecanoylphorbol Acetate | 1990 |
The effects of phorbol esters on choline phospholipid hydrolysis in heart and brain.
Topics: Animals; Brain Chemistry; Chickens; Heart; Hydrolysis; In Vitro Techniques; Male; Myocardium; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylcholines; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Phorbol esters modulate the turnover of both ether- and ester-linked phospholipids in cultured mammalian cells.
Topics: Animals; Cell Line; Choline; Ethanolamines; HeLa Cells; Humans; Hydrolysis; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
Phosphatidylcholine hydrolysis stimulated by phorbol myristate acetate is mediated principally by phospholipase D in endothelial cells.
Topics: Alkaloids; Animals; Cattle; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Ethanol; Hydrolysis; Kinetics; Phosphatidylcholines; Phospholipase D; Phospholipases; Pulmonary Artery; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Regulation of sn-1,2-diacylglycerol second-messenger formation in thrombin-stimulated human platelets. Potentiation by protein kinase C inhibitors.
Topics: Alkaloids; Blood Platelets; Carbazoles; Diglycerides; Drug Synergism; Enzyme Activation; Feedback; Glycerides; Humans; Indole Alkaloids; Neomycin; Phosphatidic Acids; Phosphatidylcholines; Phosphorylation; Propranolol; Protein Kinase C; Second Messenger Systems; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Regulation of intracellular free arachidonic acid in Aplysia nervous system.
Topics: Acetophenones; Animals; Aplysia; Arachidonic Acids; Calcium; Dose-Response Relationship, Drug; Neurons; Phosphatidylcholines; Phosphatidylinositols; Phospholipases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Phorbol diesters stimulate the accumulation of phosphatidate, phosphatidylethanol, and diacylglycerol in three cell types. Evidence for the indirect formation of phosphatidylcholine-derived diacylglycerol by a phospholipase D pathway and direct formation
Topics: Animals; Cell Line; Diglycerides; Ethanol; Glycerides; Glycerophospholipids; Hydrolysis; Kinetics; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1990 |
Modulation of a human lymphoblastoid B cell line by cyclic AMP. Ig secretion and phosphatidylcholine metabolism.
Topics: 1-Methyl-3-isobutylxanthine; Adjuvants, Immunologic; B-Lymphocytes; Bucladesine; Cell Line, Transformed; Cholera Toxin; Choline; Colforsin; Cyclic AMP; Humans; Immunoglobulins; Phosphatidylcholines; Phosphorus Radioisotopes; Tetradecanoylphorbol Acetate | 1988 |
Synergistic enhancement of histamine release from rat peritoneal mast cells by the phorbol ester 12-O-tetradecanoylphorbol 13-acetate is not reflected by corresponding changes in phospholipid turnover.
Topics: Animals; Antibodies, Anti-Idiotypic; Calcimycin; Drug Synergism; Histamine Release; Immunoglobulin E; Male; Mast Cells; Peritoneal Cavity; Phosphates; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Phospholipids; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
A phospholipase A2 hydrolyzing arachidonoyl-phospholipids in mouse peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cells, Cultured; Cytosol; Glycerol; Hydrogen-Ion Concentration; Macrophages; Masoprocol; Mice; Peritoneal Cavity; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Quercetin; Tetradecanoylphorbol Acetate | 1989 |
Stimulation of phosphatidylcholine hydrolysis, diacylglycerol release, and arachidonic acid production by oncogenic ras is a consequence of protein kinase C activation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Diglycerides; Enzyme Activation; Glycerides; Hydrolysis; Insulin; Kinetics; Membrane Proteins; Mice; Phosphatidylcholines; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate | 1989 |
Hormonal stimulation of diacylglycerol formation in hepatocytes. Evidence for phosphatidylcholine breakdown.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Angiotensin II; Animals; Arginine Vasopressin; Calcimycin; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diglycerides; Egtazic Acid; Epinephrine; Fatty Acids; Glucagon; Glycerides; Hormones; Kinetics; Liver; Male; Phosphatidylcholines; Phospholipids; Rats; Tetradecanoylphorbol Acetate | 1989 |
Regulation of lung surfactant secretion by intracellular pH.
Topics: Acetates; Adenosine Triphosphate; Ammonium Chloride; Animals; Butyrates; Butyric Acid; Carbon Dioxide; Choline; Homeostasis; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lung; Male; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Terbutaline; Tetradecanoylphorbol Acetate; Therapeutic Irrigation | 1989 |
Phorbol myristate enhanced specific incorporation of arachidonic acid into phospholipids through lysophospholipid acyltransferase in cultured smooth muscle cells.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acetyltransferases; Acyl Coenzyme A; Acyltransferases; Analysis of Variance; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dinoprostone; Enzyme Activation; Fatty Acids, Unsaturated; Lipopolysaccharides; Lysophosphatidylcholines; Muscle, Smooth; Phosphatidylcholines; Phospholipases; Phospholipids; Rabbits; Substrate Specificity; Tetradecanoylphorbol Acetate | 1989 |
Evidence for a protein kinase C-directed mechanism in the phorbol diester-induced phospholipase D pathway of diacylglycerol generation from phosphatidylcholine.
Topics: Alkaloids; Animals; Bucladesine; Cell Line; Choline; Colforsin; Diglycerides; Embryo, Mammalian; Fibroblasts; Glycerides; Glycerophospholipids; Hydrolysis; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Muscarinic receptor activation of phosphatidylcholine hydrolysis. Relationship to phosphoinositide hydrolysis and diacylglycerol metabolism.
Topics: Arachidonic Acid; Arachidonic Acids; Astrocytoma; Calcium; Carbachol; Cell Line; Choline; Diglycerides; Glycerides; Humans; Hydrolysis; Intracellular Fluid; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tritium | 1989 |
Analysis of the water-soluble products of phosphatidylcholine breakdown by ion-exchange chromatography. Bombesin and TPA (12-O-tetradecanoylphorbol 13-acetate) stimulate choline generation in Swiss 3T3 cells by a common mechanism.
Topics: Bombesin; Cell Line; Choline; Chromatography, Ion Exchange; Fibroblasts; Glycerylphosphorylcholine; Kinetics; Phosphatidylcholines; Phosphorylcholine; Solubility; Tetradecanoylphorbol Acetate; Tritium; Water | 1989 |
[Effect of palmitate and phorbol ester on synthesis of phosphatidylcholine in isolated guinea pig gastric glands].
Topics: Animals; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Male; Palmitates; Palmitic Acids; Phosphatidylcholines; Stimulation, Chemical; Stomach; Tetradecanoylphorbol Acetate | 1989 |
A phospholipase D-like mechanism in pancreatic islet cells: stimulation by calcium ionophore, phorbol ester and sodium fluoride.
Topics: Animals; Autoradiography; Choline; Chromatography, Thin Layer; Diglycerides; Enzyme Activation; Ethers; Glycerylphosphorylcholine; Ionomycin; Ionophores; Islets of Langerhans; Phosphatidylcholines; Phospholipase D; Phospholipases; Phospholipids; Rats; Sodium Fluoride; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1989 |
Stimulation of phosphatidylcholine breakdown and diacylglycerol production by growth factors in Swiss-3T3 cells.
Topics: Animals; Bombesin; Bradykinin; Cells, Cultured; Diglycerides; Dinoprost; Epidermal Growth Factor; Glycerides; Growth Substances; Hydrolysis; Insulin; Kinetics; Mice; Phosphatidylcholines; Platelet-Derived Growth Factor; Tetradecanoylphorbol Acetate; Vasopressins | 1989 |
Reactive blue 2 selectively inhibits P2y-purinoceptor-stimulated surfactant phospholipid secretion from rat isolated alveolar type II cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Male; Phosphatidylcholines; Phospholipids; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Receptors, Purinergic; Terbutaline; Tetradecanoylphorbol Acetate; Triazines | 1989 |
Involvement of protein kinase C in platelet-activating factor-stimulated diacylglycerol accumulation in murine peritoneal macrophages.
Topics: Animals; Diglycerides; Ethers; Glycerides; Hydrolysis; Ionomycin; Ionophores; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phosphatidylcholines; Phosphatidylinositols; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Uptake of exogenous phosphatidylserine by human neuroblastoma cells stimulates the incorporation of [methyl-14C]choline into phosphatidylcholine.
Topics: Biological Transport; Choline; Enzyme Activation; Humans; Neuroblastoma; Phosphatidylcholines; Phosphatidylserines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Interruption of TPA-induced signals by an antiviral and antitumoral xanthate compound: inhibition of a phospholipase C-type reaction.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Bridged-Ring Compounds; Cell Line; Cricetinae; Diglycerides; Fibroblasts; Humans; Norbornanes; Phosphatidylcholines; Phospholipids; Signal Transduction; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Tumor Cells, Cultured; Type C Phospholipases | 1989 |
Differential activation by fMet-Leu-Phe and phorbol ester of a plasma membrane phosphatidylcholine-specific phospholipase D in human neutrophil.
Topics: Cell Membrane; Cytochalasin B; Enzyme Activation; Humans; Hydrolysis; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Phospholipase D; Phospholipases; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Effect of secretagogues on cytoplasmic free calcium in alveolar type II epithelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminoquinolines; Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Cytoplasm; Enzyme Activation; Epithelium; Ethers; Fluorescent Dyes; Ionomycin; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Terbutaline; Tetradecanoylphorbol Acetate | 1987 |
Functional evidence for involvement of P2 purinoceptors in the ATP stimulation of phosphatidylcholine secretion in type II alveolar epithelial cells.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Cyclic AMP; Epithelium; Kinetics; Lung; Male; Phosphatidylcholines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Terbutaline; Tetradecanoylphorbol Acetate | 1988 |
Vasopressin, phorbol diesters and serum elicit choline glycerophospholipid hydrolysis and diacylglycerol formation in nontransformed cells: transformed derivatives do not respond.
Topics: Animals; Blood; Cell Line; Cell Transformation, Neoplastic; Culture Media; Diglycerides; Embryo, Mammalian; Glycerides; Kinetics; Phorbol Esters; Phosphatidylcholines; Rats; Simian virus 40; Tetradecanoylphorbol Acetate; Vasopressins | 1988 |
Synergism between vasopressin and phorbol esters in stimulation of insulin secretion and phosphatidylcholine metabolism in RIN insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Arginine Vasopressin; Cell Line; Drug Synergism; Insulinoma; Kinetics; Pancreatic Neoplasms; Phloretin; Phosphatidylcholines; Rats; Tamoxifen; Tetradecanoylphorbol Acetate | 1988 |
Human platelet activation by bacterial phospholipase C: mechanism of inhibition by flurazepam.
Topics: Alprostadil; Biomechanical Phenomena; Blood Platelets; Blood Proteins; Clostridium perfringens; Diglycerides; Ethers; Flurazepam; Humans; Hydrolysis; Ionomycin; Phosphatidylcholines; Phosphoproteins; Phosphorylation; Platelet Aggregation; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Alterations of phospholipid metabolism by phorbol esters and fatty acids occur by different intracellular mechanisms in cultured glioma, neuroblastoma, and hybrid cells.
Topics: Animals; Cell Line; Choline; Ethanolamine; Ethanolamines; Fatty Acids; Glioma; Hybrid Cells; Kinetics; Neuroblastoma; Phosphatidylcholines; Phospholipids; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1989 |
Platelet-activating factor stimulates prolactin release from dispersed rat anterior pituitary cells in vitro.
Topics: Animals; Bromocriptine; Cells, Cultured; Dose-Response Relationship, Drug; Growth Hormone; Kinetics; Luteinizing Hormone; Male; Phosphatidylcholines; Pituitary Gland, Anterior; Platelet Activating Factor; Prolactin; Rats; Tetradecanoylphorbol Acetate; Thyrotropin | 1989 |
Phorbol ester-induced activation of protein kinase C leads to increased formation of diacylglycerol in human neutrophils.
Topics: Calcium; Diglycerides; Enzyme Activation; Glycerides; Humans; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Oxidant membrane injury by the neutrophil myeloperoxidase system. II. Injury by stimulated neutrophils and protection by lipid-soluble antioxidants.
Topics: Antioxidants; Cell Membrane; Chromium Radioisotopes; Humans; Iodides; Liposomes; Neutrophils; Oxygen; Peroxidase; Peroxidases; Phosphatidylcholines; Tetradecanoylphorbol Acetate | 1985 |
Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.
Topics: Cell Differentiation; Cell Division; Cell Line; Diglycerides; Enzyme Activation; Humans; Leukemia, Myeloid, Acute; Neoplasm Proteins; Phorbols; Phosphatidylcholines; Phosphorylation; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate | 1985 |
Involvement of protein kinase C in pulmonary surfactant secretion from alveolar type II cells.
Topics: Animals; Cyclic AMP; Cytosol; Diglycerides; Drug Interactions; Phosphatidylcholines; Protein Kinase C; Protein Kinases; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Terbutaline; Tetracaine; Tetradecanoylphorbol Acetate | 1985 |
The effect of cAMP on tumour promoter responses mediated by C-kinase.
Topics: Aminophylline; Animals; Bucladesine; Carcinogens; Cell Communication; Cell Line; Cyclic AMP; Diglycerides; Epidermal Growth Factor; Glycerides; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Cyclic AMP-like effects of polyamines on phosphatidylcholine synthesis and protein phosphorylation in human promyelocytic leukemia HL60 cells. Comparison with the effects of phorbol ester.
Topics: Bucladesine; Cell Line; Cyclic AMP; Drug Synergism; Humans; Leukemia, Myeloid; Phosphatidylcholines; Phosphoproteins; Phosphorylation; Polyamines; Protein Kinase C; Protein Kinases; Putrescine; Spermine; Tetradecanoylphorbol Acetate | 1987 |
Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: specific induction of a long-lived state of proliferative nonresponsiveness.
Topics: Animals; Antigens; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Cell Division; Cholesterol; Clone Cells; Cytochrome c Group; Ethers; Histocompatibility Antigens Class II; Interleukin-2; Interleukin-3; Ionomycin; Lymphocyte Activation; Membranes; Mice; Phosphatidylcholines; Receptors, Antigen, T-Cell; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1987 |
Comparative effects of polymyxin B, phorbol ester and bryostatin on protein phosphorylation, protein kinase C translocation, phospholipid metabolism and differentiation of HL60 cells.
Topics: Bryostatins; Cell Adhesion; Cell Differentiation; Cell Line; Dinoprostone; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Phorbol Esters; Phosphatidylcholines; Phospholipids; Phosphorylation; Polymyxin B; Polymyxins; Prostaglandins E; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate | 1987 |
Mechanism of polymorphonuclear leukocyte activation by myristate. Involvement of calcium ion and protein kinase C.
Topics: Animals; Biological Transport, Active; Brain; Calcium; Cell Membrane; Cholesterol; Guinea Pigs; In Vitro Techniques; Kinetics; Liposomes; Male; Membrane Potentials; Neutrophils; Phosphatidylcholines; Protein Kinase C; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Effects of insulin and phorbol esters on diacylglycerol generation and synthesis and hydrolysis of phosphatidylcholine in BC3H-1 myocytes.
Topics: Animals; Cell Line; Choline; Diglycerides; Glycerides; Glycerol; Insulin; Kinetics; Muscles; Phosphatidylcholines; Phosphorylcholine; Tetradecanoylphorbol Acetate | 1988 |
A novel mechanism of diglyceride formation. 12-O-tetradecanoylphorbol-13-acetate stimulates the cyclic breakdown and resynthesis of phosphatidylcholine.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Choline; Diglycerides; Dogs; Glycerides; Kidney; Palmitic Acid; Palmitic Acids; Phorbols; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1986 |
Thyrotropin-releasing hormone and phorbol esters induce phosphatidylcholine synthesis in GH3 pituitary cells. Evidence for stimulation via protein kinase C.
Topics: Cell Line; Choline; Dose-Response Relationship, Drug; Kinetics; Phosphates; Phosphatidylcholines; Pituitary Gland; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1987 |
Phorbol ester stimulation of sphingomyelin synthesis in human leukemic HL60 cells.
Topics: Bryostatins; Cell Line; Choline; Diterpenes; Enzyme Activation; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Phosphatidylcholines; Phosphorylation; Protein Kinase C; Sphingomyelins; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
The role of hydrophobic interactions in the phospholipid-dependent activation of protein kinase C.
Topics: Animals; Calcium; Enzyme Activation; Fatty Acids; Liposomes; Macromolecular Substances; Mice; Microscopy, Electron; Models, Biological; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
Insulin-induced glycerolipid mediators and the stimulation of glucose transport in BC3H-1 myocytes.
Topics: Animals; Biological Transport, Active; Calcium; Cell Line; Cytosol; Deoxy Sugars; Deoxyglucose; Diglycerides; Glycerides; Insulin; Kinetics; Phorbol Esters; Phosphatidylcholines; Pyruvate Dehydrogenase Complex; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Regulation of surfactant phospholipid secretion from isolated rat alveolar type II cells by lectins.
Topics: Acetylglucosamine; Adenosine Triphosphate; Animals; Concanavalin A; In Vitro Techniques; Lectins; Male; Methylmannosides; Phosphatidylcholines; Proteolipids; Pulmonary Alveoli; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Tetradecanoylphorbol Acetate; Wheat Germ Agglutinins | 1988 |
Positive correlation between cytosolic free calcium and surfactant secretion in cultured rat alveolar type II cells.
Topics: Aminoquinolines; Animals; Benzofurans; Calcium; Cells, Cultured; Cytosol; Ethers; Fura-2; Ionomycin; Male; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Terbutaline; Tetradecanoylphorbol Acetate | 1988 |
The phosphatidylcholine pathway of diacylglycerol formation stimulated by phorbol diesters occurs via phospholipase D activation.
Topics: Animals; Cell Line; Choline; Diglycerides; Embryo, Mammalian; Enzyme Activation; Glycerides; Kinetics; Myristic Acid; Myristic Acids; Phorbol Esters; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases; Propranolol; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1988 |
Mimicry of phorbol ester responses by diacylglycerols. Differential effects on phosphatidylcholine biosynthesis, cell-cell communication and epidermal growth factor binding.
Topics: Animals; Cell Communication; Cell Line; Diglycerides; Epidermal Growth Factor; Epidermis; Glycerides; Intercellular Junctions; Mice; Phorbols; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Bombesin and phorbol ester stimulate phosphatidylcholine hydrolysis by phospholipase C: evidence for a role of protein kinase C.
Topics: Animals; Bombesin; Carcinogens; Cells, Cultured; Hydrolysis; Kinetics; Mice; Phosphatidylcholines; Phospholipids; Protein Kinase C; Quinazolines; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
1,2-Diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action.
Topics: Animals; Cytidine Diphosphate Choline; Diglycerides; Glycerides; Phorbol Esters; Phosphatidylcholines; Pituitary Neoplasms; Rats; Stearic Acids; Tetradecanoylphorbol Acetate | 1987 |
Direct evidence for phorbol ester-stimulated accumulation of diacylglycerol derived from phosphatidylcholine.
Topics: Cell Membrane; Chromatography, Thin Layer; Diglycerides; Glycerides; HeLa Cells; Humans; Phorbol Esters; Phosphatidylcholines; Tetradecanoylphorbol Acetate | 1987 |
Differential regulation of phosphatidylcholine biosynthesis by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Choline; Chromatography, High Pressure Liquid; Diglycerides; Glioma; Glycerides; Hybrid Cells; Isoquinolines; Neuroblastoma; Phosphatidylcholines; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
The interaction of protein kinase C and other specific cytoplasmic proteins with phospholipid bilayers.
Topics: Affinity Labels; Animals; Azides; Calcium; Cytoplasm; Diglycerides; HeLa Cells; Humans; Iodine Radioisotopes; Liposomes; Mice; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Photochemistry; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate | 1986 |
Effect of phorbol esters and liposome-delivered phospholipids on the differentiation program of normal and dystrophic satellite cells.
Topics: Animals; Cell Differentiation; Culture Techniques; Liposomes; Mice; Muscle Proteins; Muscles; Muscular Dystrophy, Animal; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Phosphatidylcholine biosynthesis in the neuroblastoma-glioma hybrid cell line NG108-15: stimulation by phorbol esters.
Topics: Animals; Cell Line; Choline; Ethanolamine; Ethanolamines; Glioma; Inositol; Neuroblastoma; Phorbol Esters; Phosphatidylcholines; Rats; Tetradecanoylphorbol Acetate | 1986 |
Postsynaptic effects of the phorbol ester TPA on frog end-plates.
Topics: Acetylcholine; Animals; Diglycerides; In Vitro Techniques; Isotonic Solutions; Membrane Potentials; Motor Endplate; Neostigmine; Neuromuscular Junction; Phosphatidylcholines; Ranidae; Ringer's Solution; Tetradecanoylphorbol Acetate | 1986 |
Co-mitogenic tumor promoters suppress the phosphatidylinositol response in lymphocytes during early mitogenesis.
Topics: Animals; Carcinogens; Female; Humans; Lymphocyte Activation; Mice; Phorbol Esters; Phorbols; Phosphates; Phosphatidylcholines; Phosphatidylinositols; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine | 1985 |
Regulation of phosphatidylcholine synthesis and the activity of CTP-cholinephosphate cytidylytransferase in myoblasts by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cells, Cultured; Choline-Phosphate Cytidylyltransferase; Cytidine Triphosphate; Enzyme Activation; Muscles; Nucleotidyltransferases; Phorbols; Phosphates; Phosphatidylcholines; Phospholipids; Rats; Tetradecanoylphorbol Acetate | 1984 |
A possible role of protein alkylation in phorbol ester action.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Alkylation; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Choline-Phosphate Cytidylyltransferase; Enzyme Activation; Lymphocyte Activation; Lymphocytes; Nucleotidyltransferases; Oxygen; Phorbols; Phosphatidylcholines; Phytohemagglutinins; Proteins; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Activation of protein kinase C by a tumor-promoting phorbol ester in pancreatic islets.
Topics: Animals; Calcium; Choline; Diglycerides; Enzyme Activation; Insulin; Insulin Secretion; Islets of Langerhans; Phorbols; Phosphatidylcholines; Phosphatidylinositols; Phosphorus Radioisotopes; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1984 |
Regulation of phosphatidylcholine biosynthesis by mitogenic growth factors.
Topics: Animals; Blood; Choline; Choline Kinase; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Insulin; Mice; Peptides; Phosphatidylcholines; Somatomedins; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Phorbol ester tumor promoters specifically stimulate choline phospholipid metabolism in human leukemic cells.
Topics: Acetates; Acetic Acid; Caenorhabditis elegans Proteins; Carbon Radioisotopes; Carcinogens; Carrier Proteins; Cells, Cultured; Choline; Humans; Leukemia, Hairy Cell; Microscopy, Electron, Scanning; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylcholines; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tritium | 1984 |
The phorbol ester 12-0-tetradecanoyl-phorbol-13-acetate and stimulation of 3H-choline incorporation into endoplasmic reticulum membranes and other subcellular fractions of Krebs II ascites cells during in vitro incubation.
Topics: Animals; Carcinoma, Krebs 2; Cells, Cultured; Endoplasmic Reticulum; Intracellular Membranes; Mice; Phorbols; Phosphatidylcholines; Stimulation, Chemical; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
Interaction of phorbol esters with lipid bilayers : thermotropic changes in fluorescence polarization, phase transition and calcium ionophoresis.
Topics: Calcimycin; Calcium; Carcinogens; Diffusion; Dimyristoylphosphatidylcholine; Lipid Bilayers; Phorbol Esters; Phorbols; Phosphatidylcholines; Pulmonary Surfactants; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Tetradecanoylphorbol Acetate | 1981 |
Tumor promoter 12-O-tetradecanoylphorbol 13-acetate alters state, fluidity and hydration of 1,2-diacyl-sn-glycero-3-phosphocholine bilayers.
Topics: Calorimetry, Differential Scanning; Diphenylhexatriene; Fluorescence Polarization; Lipid Bilayers; Models, Biological; Molecular Conformation; Phorbols; Phosphatidylcholines; Tetradecanoylphorbol Acetate | 1983 |
Early changes in phosphatidylcholine metabolism in human acute promyelocytic leukemia cells stimulated to differentiate by phorbol ester.
Topics: Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Methylation; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipids; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Tumor promoter stimulation of phosphatidylcholine turnover in HeLa cells.
Topics: Choline; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; HeLa Cells; Humans; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipases; Phospholipids; Phosphorylcholine; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Effects of 12-O-tetradecanoylphorbol 13-acetate on glycerolipid metabolism in cultured myoblasts.
Topics: Animals; Calcium; Cells, Cultured; Chick Embryo; Cycloheximide; Diglycerides; Fatty Acids; Glycerides; Membrane Lipids; Muscles; Phorbols; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Tetradecanoylphorbol Acetate | 1982 |
Alterations in lipid metabolism induced by 12-O-tetradecanoylphorbol-13-acetate in differentiating human myeloid leukemia cells.
Topics: Animals; Cell Differentiation; Cell Membrane; Cells, Cultured; Diglycerides; Humans; Leukemia, Experimental; Lipid Metabolism; Neoplasm Proteins; Phorbols; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Tetradecanoylphorbol Acetate; Triglycerides | 1980 |
Lack of correlation between effects of tumor promoter TPA on plasminogen activator production, phosphatidyl choline synthesis, and hexose transport in mammalian cell culture systems.
Topics: Animals; Biological Transport, Active; Cell Line; Cells, Cultured; Choline; Cricetinae; Cricetulus; Female; HeLa Cells; Hexoses; Humans; Kidney; Leukemia, Experimental; Lymphocytes; Mice; Mice, Inbred BALB C; Ovary; Phorbols; Phosphatidylcholines; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate | 1980 |
SCF/c-kit receptor-mediated arachidonic acid liberation in rat mast cells. Involvement of PLD activation associated tyrosine phosphorylation.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Diglycerides; Genistein; Hematopoietic Cell Growth Factors; Isoflavones; Kinetics; Mast Cells; Myristic Acid; Myristic Acids; Phosphatidylcholines; Propranolol; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptors, Colony-Stimulating Factor; Stem Cell Factor; Tetradecanoylphorbol Acetate; Vanadates | 1993 |
Mechanism of interaction of protein kinase C with phorbol esters. Reversibility and nature of membrane association.
Topics: Calcium; Diglycerides; Kinetics; Liposomes; Membrane Fluidity; Osmolar Concentration; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylcholines; Protein Binding; Protein Kinase C; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Tryptophan | 1995 |
Independent regulation of cholesterol incorporation into free apolipoprotein-mediated cellular lipid efflux in rat vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Apolipoprotein A-I; Cells, Cultured; Cholesterol; Cholesterol, LDL; Emulsions; Humans; Kinetics; Lipoproteins, HDL; Macrophage Colony-Stimulating Factor; Muscle, Smooth, Vascular; Phosphatidylcholines; Platelet-Derived Growth Factor; Rats; Tetradecanoylphorbol Acetate | 1995 |
Effect of platelet-derived growth factor on phosphatidylcholine-hydrolyzing phospholipase D in osteoblast-like cells.
Topics: Animals; Calcium; Cells, Cultured; Choline; Cinnamates; DNA; Enzyme Activation; Genistein; Inositol Phosphates; Isoflavones; Mice; Osteoblasts; Phosphatidylcholines; Phospholipase D; Platelet-Derived Growth Factor; Tetradecanoylphorbol Acetate | 1995 |
Activation mechanism of phospholipase D involved in the generation of lipid mediators in cultured Madin-Darby canine kidney cells.
Topics: Animals; Arachidonic Acids; Cell Line; Cell-Free System; Choline; Deoxyglucose; Dinoprostone; Dogs; Eicosanoids; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Kidney; Lipid Metabolism; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1995 |
Wortmannin has opposite effects on phorbol ester-induced DNA synthesis and phosphatidylcholine hydrolysis.
Topics: 3T3 Cells; Androstadienes; Animals; DNA; Glycerophospholipids; Hydrolysis; Mice; Palmitic Acid; Palmitic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Tetradecanoylphorbol Acetate; Wortmannin | 1995 |
Synthesis of phosphatidyl[3H]butanol molecular species by phospholipase D in HL60 granulocytes.
Topics: Animals; Butanols; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Glycerophospholipids; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Liver; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Radioisotope Dilution Technique; Rats; Tetradecanoylphorbol Acetate; Tretinoin; Tritium; Tumor Cells, Cultured | 1995 |
Substrate selectivity of phospholipase D in HL60 granulocytes: effects of fatty acid supplementation.
Topics: Butanols; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Fatty Acids; Glycerophospholipids; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Substrate Specificity; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
Phospholipase D does not mediate alcohol inhibition of [3H]-noradrenaline release from SH-SY5Y cells.
Topics: Bradykinin; Butanols; Carbachol; Cell Line; Humans; Ionomycin; Kinetics; Methacholine Chloride; Neuroblastoma; Norepinephrine; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Potassium; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 1994 |
Alteration of lipid composition modulates Fc epsilon RI signaling in RBL-2H3 cells.
Topics: Antigens; Arachidonic Acid; Calcimycin; Cell Degranulation; Cell Line; Cell Membrane; Cholesterol; Dinitrophenols; Liposomes; Membrane Lipids; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phospholipids; Receptors, IgE; Serotonin; Serum Albumin, Bovine; Signal Transduction; Sonication; Sphingomyelins; Tetradecanoylphorbol Acetate; Tritium | 1995 |
The molecular selectivity of phospholipase D in HL60 granulocytes.
Topics: Butanols; Cell Line; Chromatography, High Pressure Liquid; Glycerophospholipids; Granulocytes; Humans; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Substrate Specificity; Tetradecanoylphorbol Acetate; Tritium | 1995 |
Phosphatidylcholine-phospholipase C mediates the induction of nerve growth factor in cultured glial cells.
Topics: Animals; Blotting, Northern; Brain; Cells, Cultured; Enzyme Activation; Hydrolysis; Nerve Growth Factors; Neuroglia; Phosphatidylcholines; Protein Kinase C; Rats; RNA, Messenger; Sphingosine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1995 |
Phosphatidylcholine turnover in activated human neutrophils. Agonist-induced cytidylyltransferase translocation is subsequent to phospholipase D activation.
Topics: Biological Transport; Catalysis; Choline; Choline-Phosphate Cytidylyltransferase; Cytochalasin B; Enzyme Activation; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Nucleotidyltransferases; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1995 |
Evidence for involvement of phosphatidylcholine-phospholipase C and protein kinase C in transforming growth factor-beta signaling.
Topics: Alkaloids; Bridged-Ring Compounds; GTP-Binding Proteins; Humans; Norbornanes; Phosphatidylcholines; Plasminogen Activator Inhibitor 1; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Transforming Growth Factor beta; Tumor Cells, Cultured; Type C Phospholipases | 1995 |
Effect of Escherichia coli lipopolysaccharide on surfactant secretion in primary cultures of rat type II pneumocytes.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Escherichia coli; L-Lactate Dehydrogenase; Lipopolysaccharides; Male; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1995 |
Phorbol ester stimulates choline uptake in Swiss 3T3 fibroblasts following introduction of the gene encoding protein kinase C alpha.
Topics: 3T3 Cells; Animals; Biological Transport; Blotting, Western; Carbon Radioisotopes; Choline; Dose-Response Relationship, Drug; Isoenzymes; Isotope Labeling; Mice; Phosphatidylcholines; Phosphorylcholine; Protein Kinase C; Protein Kinase C-alpha; Recombinant Proteins; Sphingosine; Tetradecanoylphorbol Acetate | 1995 |
Protein kinase C in ATP regulation of lung surfactant secretion in type II cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Diglycerides; Lipids; Male; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1995 |
High-density lipoprotein 3 stimulates phosphatidylcholine breakdown and sterol translocation in rat aortic smooth muscle cells by a phospholipase C/protein kinase C-dependent process.
Topics: Animals; Aorta, Thoracic; Carbachol; Cell Membrane; Cholesterol; Lipoproteins, HDL; Lipoproteins, HDL3; Muscle, Smooth, Vascular; Phosphatidylcholines; Protein Kinase C; Rats; Signal Transduction; Sterols; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1994 |
Rapid heterologous desensitization of muscarinic and thrombin receptor-mediated phospholipase D activation.
Topics: Astrocytoma; Carbachol; Chemical Fractionation; Down-Regulation; Enzyme Activation; Ethanol; Glycerophospholipids; Humans; Hydrolysis; Immunoblotting; Muscarinic Agonists; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinases; Receptors, Thrombin; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1994 |
Phorbol ester selectively stimulates the phospholipase D-mediated hydrolysis of phosphatidylethanolamine in multidrug-resistant MCF-7 human breast carcinoma cells.
Topics: Breast Neoplasms; Drug Resistance, Multiple; Glycerophospholipids; Glycerylphosphorylcholine; Humans; Hydrogen Peroxide; Hydrolysis; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Prostaglandin F2 alpha activates phospholipase D independently from activation of protein kinase C in osteoblast-like cells.
Topics: Alkaloids; Cell Line; Choline; Dinoprost; Enzyme Activation; GTP-Binding Proteins; Hydrolysis; Osteoblasts; Pertussis Toxin; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1994 |
P2u purinoceptor stimulation of surfactant secretion coupled to phosphatidylcholine hydrolysis in type II cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Gene Expression; Hydrolysis; Male; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Uridine Triphosphate; Xanthines | 1994 |
Phospholipid analogues: side chain- and polar head group-dependent effects on phosphatidylcholine biosynthesis.
Topics: Animals; Cell Division; Cell Line; Cells, Cultured; Choline-Phosphate Cytidylyltransferase; Digitonin; Dogs; Kidney; Nucleotidyltransferases; Phosphatidylcholines; Phospholipids; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1994 |
Selective down-regulation of protein kinase c-epsilon by carcinogens does not prevent stimulation of phospholipase D by phorbol ester and platelet-derived growth factor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Benzo(a)pyrene; Carcinogens; Cell Line; Isoenzymes; Mice; Mice, Inbred C3H; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Platelet-Derived Growth Factor; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
High-performance liquid chromatographic study of the regulation of phospholipid metabolism in cultured adrenocortical cells.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Animals; Cardiolipins; Cells, Cultured; Chromatography, High Pressure Liquid; Glycerol; Indicators and Reagents; Mice; Palmitates; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Endothelin stimulates phosphatidylcholine hydrolysis through both PLC and PLD pathways in mesangial cells.
Topics: Animals; Diglycerides; Endothelins; Glomerular Mesangium; Hydrolysis; Male; Phosphatidylcholines; Phospholipase D; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1994 |
Increased surfactant internalization by rat type II cells cultured on microporous membranes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Cell Differentiation; Cell Separation; Cells, Cultured; Choline; Drug Carriers; Liposomes; Male; Methionine; Microscopy, Electron; Perfusion; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes; Terbutaline; Tetradecanoylphorbol Acetate; Tritium | 1993 |
Inhibition of protein kinase C of human neutrophils by phosphatidylcholines.
Topics: Analysis of Variance; Calcium; Cytosol; Diglycerides; Humans; In Vitro Techniques; Neutrophils; Phosphatidylcholines; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1994 |
The zinc chelator 1,10-phenanthroline enhances the stimulatory effects of protein kinase C activators and staurosporine, but not sphingosine and H2O2, on phospholipase D activity in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Alkaloids; Animals; Chelating Agents; Enzyme Activation; Hydrogen Peroxide; Hydrolysis; Mice; Phenanthrolines; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Zinc | 1994 |
1,25(OH)2-vitamin D3 signal transduction in chick myoblasts involves phosphatidylcholine hydrolysis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcitriol; Calcium Channel Blockers; Cells, Cultured; Chick Embryo; Diglycerides; Enzyme Activation; Ethanol; In Vitro Techniques; Isoquinolines; Muscles; Neomycin; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Piperazines; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Influence of protein kinase C activation by 4 beta-phorbol ester or 1-oleoyl-2-acetylglycerol on disaturated phosphatidylcholine synthesis and secretion, and protein phosphorylation in differentiating fetal rabbit type II alveolar cells.
Topics: Animals; Binding Sites; Cell Differentiation; Cells, Cultured; Diglycerides; Enzyme Activation; Fetus; Phosphatidylcholines; Phosphatidylserines; Phosphorylation; Protein Kinase C; Pulmonary Alveoli; Pulmonary Surfactants; Rabbits; Tetradecanoylphorbol Acetate | 1994 |
Sphingosine-like stimulatory effects of propranolol on phospholipase D activity in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Carbon Radioisotopes; Diglycerides; Drug Synergism; Mice; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Propranolol; Sphingosine; Tetradecanoylphorbol Acetate | 1994 |
Evidence that v-Src-induced phospholipase D activity is mediated by a G protein.
Topics: 3T3 Cells; Adenine Nucleotides; Aluminum Compounds; Animals; Arachidonic Acid; Avian Sarcoma Viruses; Benzoquinones; Cell Line, Transformed; Cholera Toxin; Enzyme Induction; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Lactams, Macrocyclic; Mice; Mice, Inbred BALB C; Myristic Acid; Myristic Acids; Oncogene Protein pp60(v-src); Phosphatidylcholines; Phospholipase D; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1994 |
Hydrogen peroxide regulates phospholipase D-mediated hydrolysis of phosphatidylethanolamine and phosphatidylcholine by different mechanisms in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Alkaloids; Animals; Fibroblasts; Hydrogen Peroxide; Hydrolysis; Kinetics; Mice; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Sphingosine; Staurosporine; Substrate Specificity; Tetradecanoylphorbol Acetate | 1994 |
The phospholipase-A2 reaction leads to increased monocyte adhesion of endothelial cells via the expression of adhesion molecules.
Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Line; Endothelium, Vascular; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-1; Leukemia; Lipopolysaccharides; Lysophosphatidylcholines; Monocytes; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Cord | 1993 |
Activation of actin polymerization by phosphatidic acid derived from phosphatidylcholine in IIC9 fibroblasts.
Topics: Actins; Animals; Bacillus cereus; Cell Line; Cricetinae; Cricetulus; Diglycerides; Embryo, Mammalian; Fibroblasts; Kinetics; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Platelet-Derived Growth Factor; Protein Kinase C; Streptomyces; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1993 |
Secretion of surfactant protein A from rat type II pneumocytes.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cells, Cultured; Concanavalin A; Electrophoresis, Polyacrylamide Gel; Immune Sera; Ionomycin; Lectins; Lung; Molecular Weight; Phosphatidylcholines; Plant Lectins; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Receptors, Purinergic P2; Spectrophotometry; Terbutaline; Tetradecanoylphorbol Acetate | 1993 |
Modulation of phorbol ester-associated events in epidermal cells by linoleate and arachidonate.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Dinoprostone; Epidermis; Kinetics; Linoleic Acid; Linoleic Acids; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
Inhibition of protein kinase C by alcohols and anaesthetics.
Topics: Alcohols; Anesthetics; Animals; Binding Sites; Brain; Diglycerides; Liposomes; Membrane Fluidity; Membrane Lipids; Phosphatidylcholines; Phosphatidylserines; Protamines; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1993 |
Dietary fatty acid modulation of events associated with mouse skin tumor promotion.
Topics: Animals; Capillary Permeability; Dietary Fats, Unsaturated; Fatty Acid Desaturases; Fatty Acids; Female; Linoleoyl-CoA Desaturase; Mice; Ornithine Decarboxylase; Phosphatidylcholines; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Phorbol myristate acetate stimulates [3H]choline incorporation into phosphatidylcholine independently of the 'de novo' pathway in Krebs-II ascitic cells: a unique effect of phorbol ester on choline uptake.
Topics: Animals; Ascites; Biological Transport; Carcinoma, Krebs 2; Choline; Diglycerides; Mice; Oleic Acid; Oleic Acids; Phosphatidylcholines; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Protein kinase C-dependent stimulation of phospholipase D in phospholipase C-treated fibroblasts.
Topics: 3T3 Cells; Animals; Choline; Dose-Response Relationship, Drug; Fibroblasts; Hydrolysis; Mice; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Phosphorylcholine; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1993 |
NF-kappa B activation by ultraviolet light not dependent on a nuclear signal.
Topics: Alleles; Animals; Catechols; Cell Nucleus; Cytosol; Genes, ras; Genes, src; HeLa Cells; Humans; NF-kappa B; Nitriles; PC12 Cells; Phosphatidylcholines; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-raf; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha; Tyrphostins; Ultraviolet Rays | 1993 |
Biphasic generation of diacylglycerol by angiotensin and phorbol ester in bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Angiotensin II; Animals; Cattle; Cells, Cultured; Choline; Diglycerides; Kinetics; Phosphatidylcholines; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Time Factors; Tritium | 1993 |
Potentiation of A2 purinoceptor-stimulated surfactant phospholipid secretion in primary cultures of rat type II pneumocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cells, Cultured; Cyclic AMP; Lung; Male; Phosphatidylcholines; Phospholipids; Protein Kinase C; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Antagonism of phorbol-ester-stimulated phosphatidylcholine biosynthesis by the phospholipid analogue hexadecylphosphocholine.
Topics: Animals; Biological Transport; Cell Division; Cell Line; Cell Survival; Choline; Choline-Phosphate Cytidylyltransferase; Digitonin; Diglycerides; Dogs; HeLa Cells; Humans; Kidney; Nucleotidyltransferases; Phosphatidylcholines; Phosphorylcholine; Tetradecanoylphorbol Acetate | 1993 |
Regulation of phospholipid turnover by steroid hormones in endometrial carcinoma and breast cancer cells.
Topics: Adenocarcinoma; Breast Neoplasms; Endometrial Neoplasms; Epidermal Growth Factor; Estradiol; Female; Gonadal Steroid Hormones; Humans; Neoplasms, Hormone-Dependent; Phosphatidylcholines; Phosphatidylinositols; Phospholipids; Progesterone; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Phospholipase D hydrolysis of choline phosphoglycerides is selective for the alkyl-linked subclass of Madin-Darby canine kidney cells.
Topics: Alkylation; Animals; Cells, Cultured; Dogs; Glycerophospholipids; Hydrolysis; Kidney; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Substrate Specificity; Tetradecanoylphorbol Acetate | 1993 |
Effect of protein kinase C inhibitors and activators on corneal re-epithelialization in the rat.
Topics: Animals; Cornea; Enzyme Inhibitors; Epithelial Cells; Epithelium; Male; Organ Culture Techniques; Phosphatidylcholines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Wound Healing | 1993 |
Characteristics of arachidonic-acid-mediated brain protein kinase C activation: evidence for concentration-dependent heterogeneity.
Topics: Animals; Arachidonic Acid; Binding Sites; Brain Chemistry; Deoxycholic Acid; Dose-Response Relationship, Drug; Enzyme Activation; Male; Phosphatidylcholines; Phosphatidylserines; Protein Kinase C; Rats; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate | 1993 |
Phosphatidylcholine hydrolysis and c-myc expression are in collaborating mitogenic pathways activated by colony-stimulating factor 1.
Topics: Animals; Bacillus cereus; Cell Division; Cell Line, Transformed; Diglycerides; Gene Expression Regulation; Genes, ras; Hydrolysis; Isoenzymes; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Mice, Inbred BALB C; Mitogens; Phosphatidylcholines; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA, Messenger; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1993 |
Bradykinin stimulates phospholipase D in primary cultures of guinea-pig tracheal smooth muscle.
Topics: Animals; Bradykinin; Calcium; Cells, Cultured; Glycerophospholipids; GTP-Binding Proteins; Guinea Pigs; Indomethacin; Muscle, Smooth; Palmitates; Pertussis Toxin; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Tritium; Virulence Factors, Bordetella | 1993 |
Comparison of phospholipase D activity in vasopressin- and phorbol ester-stimulated fibroblasts.
Topics: Alkaloids; Calcium; Cell Line; Enzyme Activation; Fibroblasts; Glycerol; Glycerophospholipids; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1993 |
Signal-transduction mechanisms of ATP-stimulated phosphatidylcholine secretion in rat type II pneumocytes: interactions between ATP and other surfactant secretagogues.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Drug Interactions; Ionomycin; Isoquinolines; L-Lactate Dehydrogenase; Lung; Male; Phosphatidylcholines; Piperazines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Terbutaline; Tetradecanoylphorbol Acetate; Xanthines | 1993 |
Differential translocation of protein kinase C isozymes by thrombin and platelet-derived growth factor. A possible function for phosphatidylcholine-derived diacylglycerol.
Topics: Animals; Biological Transport; Calcium; Cell Line; Cell Membrane; Chelating Agents; Choline; Cricetinae; Cricetulus; Cytosol; Diglycerides; Egtazic Acid; Inositol Phosphates; Ionomycin; Isoenzymes; Kinetics; Phosphatidylcholines; Phosphorylcholine; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Alkylphosphocholines inhibit choline uptake and phosphatidylcholine biosynthesis in rat sympathetic neurons and impair axonal extension.
Topics: Animals; Animals, Newborn; Axons; Biological Transport; Cells, Cultured; Choline; Choline-Phosphate Cytidylyltransferase; Enzyme Inhibitors; Kinetics; Neurons; Nucleotidyltransferases; Phosphatidylcholines; Phosphorylcholine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate | 1995 |
Effect of prostaglandin E2 on phospholipase D activity in osteoblast-like MC3T3-E1 cells.
Topics: 3T3 Cells; Animals; Chelating Agents; Choline; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; GTP-Binding Proteins; Inositol Phosphates; Mice; Osteoblasts; Phosphatidylcholines; Phospholipase D; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1995 |
Phosphatidylcholine could be the source of 1,2-DAG which activates protein kinase C in EGF-stimulated colon carcinoma cells (HT29).
Topics: Colonic Neoplasms; Diglycerides; Drug Interactions; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; HT29 Cells; Humans; Phosphates; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1995 |
A chemiluminescence method to analyze phosphatidylcholine-phospholipase activity in plasma membrane preparations and in intact cells.
Topics: Animals; Blood Donors; Calcimycin; Cell Membrane; Enzyme Activation; Humans; Hydrolysis; Leukocytes; Linear Models; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phospholipase D; Rats; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1995 |
Overexpression of MARCKS, but not protein kinase C-alpha, increases phorbol ester-stimulated synthesis of phosphatidylcholine in human SK-N-MC neuroblastoma cells.
Topics: Base Sequence; DNA, Complementary; Gene Expression Regulation, Enzymologic; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Neuroblastoma; Phosphatidylcholines; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Thrombin induces proliferation of osteoblast-like cells through phosphatidylcholine hydrolysis.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Calcium; Cell Division; Choline; Enzyme Inhibitors; GTP-Binding Proteins; Inositol Phosphates; Mice; Osteoblasts; Phosphatidylcholines; Phospholipase D; Phosphorylcholine; Propranolol; Protein Kinase C; Signal Transduction; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1996 |
Tyrosine kinase is involved in angiotensin II-stimulated phospholipase D activation in aortic smooth muscle cells: function of Ca2+ influx.
Topics: Alkaloids; Angiotensin II; Animals; Aorta; Biological Transport; Calcimycin; Calcium; Cells, Cultured; Choline; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Genistein; Inositol Phosphates; Ionophores; Isoflavones; Membrane Lipids; Muscle Proteins; Muscle, Smooth, Vascular; Phosphatidylcholines; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phosphoric Diester Hydrolases; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Phorbol ester stimulation of phosphatidylcholine synthesis in four cultured neural cell lines: correlations with expression of protein kinase C isoforms.
Topics: Animals; Blotting, Northern; Blotting, Western; Choline; Gene Expression; Glioma; Humans; Isoenzymes; Mice; Neuroblastoma; Oleic Acid; Oleic Acids; Phosphatidylcholines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Inhibition of phospholipase D activity by fodrin. An active role for the cytoskeleton.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Calpain; Carrier Proteins; Cattle; Cytoskeleton; Enzyme Activation; Guanosine Triphosphate; HL-60 Cells; Humans; Microfilament Proteins; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phospholipases A; Signal Transduction; Spectrin; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
Differential alterations of ethanolamine and choline phosphoglyceride metabolism by clofibrate and retinoic acid in human fibroblasts are not mediated by phorbol ester-sensitive protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinogens; Clofibrate; Enzyme Inhibitors; Ethanolamine; Ethanolamines; Fibroblasts; Humans; Hypolipidemic Agents; Isoquinolines; Phosphatidylcholines; Phospholipids; Protein Kinase C; Skin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1996 |
Protein kinase C activation inhibits stress-induced synthesis of heat shock protein 27 in osteoblast-like cells: function of arachidonic acid.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Arsenites; Choline; Cyclic AMP; Enzyme Activation; Heat-Shock Proteins; Indomethacin; Inositol Phosphates; Masoprocol; Melitten; Mice; Osteoblasts; Phosphatidylcholines; Protein Kinase C; Stress, Physiological; Tetradecanoylphorbol Acetate | 1996 |
Effects of prolonged EGF treatment on phospholipid turnover and DAG formation in murine keratinocytes.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Cells, Cultured; Diglycerides; Epidermal Growth Factor; Inositol Phosphates; Keratinocytes; Mice; Mice, Inbred BALB C; Phosphatidic Acids; Phosphatidylcholines; Phospholipids; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
Synthesis and release of phosphatidylcholine by isolated porcine gastric mucous cells in primary culture.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Separation; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Gastric Mucosa; Indomethacin; Phosphatidylcholines; Swine; Tetradecanoylphorbol Acetate | 1996 |
Function of Ca2+ in phosphatidylcholine-hydrolyzing phospholipase D activation in osteoblast-like cells.
Topics: 3T3 Cells; Animals; Calcium; Calcium Channel Blockers; Choline; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; Imidazoles; Mice; Osteoblasts; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Contribution of phosphoinositides and phosphatidylcholines to the production of phosphatidic acid upon concanavalin A stimulation of rat thymocytes.
Topics: Animals; Arachidonic Acid; Concanavalin A; Diglycerides; Hydrolysis; Male; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thymus Gland; Tritium; Type C Phospholipases | 1996 |
1H-NMR visible neutral lipids in activated T lymphocytes: relationship to phosphatidylcholine cycling.
Topics: Animals; Cell Division; Choline; Flow Cytometry; Ionomycin; Lipids; Lymphocyte Activation; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylglycerols; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1996 |
Direct proof that phorbol ester accelerates the use of choline phosphate for phosphatidylcholine synthesis in intact cells.
Topics: 3T3 Cells; Animals; Carbon Radioisotopes; Choline; Choline-Phosphate Cytidylyltransferase; Enzyme Inhibitors; Indoles; Kinetics; Maleimides; Mice; Nucleotidyltransferases; Phosphatidylcholines; Phosphorylcholine; Protein Kinase C; Radioisotope Dilution Technique; Tetradecanoylphorbol Acetate | 1996 |
Production of [3H]choline-labelled metabolites from endogenously 3H-labelled phosphatidylcholine in mouse pancreatic islets.
Topics: Animals; Carbachol; Cells, Cultured; Choline; Cyclohexanones; Diazoxide; Glucose; Glycerylphosphorylcholine; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Kinetics; Lysophosphatidylcholines; Male; Mice; Mice, Inbred Strains; Phosphatidylcholines; Potassium Chloride; Radioisotope Dilution Technique; Rats; Sodium Fluoride; Succinates; Tetradecanoylphorbol Acetate; Tolbutamide; Tritium | 1996 |
Endothelin stimulates phospholipase D in striatal astrocytes.
Topics: Animals; Astrocytes; Calcium; Cells, Cultured; Corpus Striatum; Cyclic AMP; Diglycerides; Endothelins; Enzyme Activation; GTP-Binding Proteins; Mice; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Phorbol ester-sensitive phospholipase D is mainly localized in the endoplasmic reticulum of BHK cells.
Topics: Acetic Acid; Animals; Butanols; Cells, Cultured; Centrifugation, Density Gradient; Cholesterol; Choline; Chromatography, Thin Layer; Cricetinae; Endoplasmic Reticulum; Ethanol; Glycerophospholipids; Kidney; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipids; Sphingomyelins; Tetradecanoylphorbol Acetate | 1996 |
Phosphatidylcholine cycle: an intracellular signaling mechanism in the primordial human placenta.
Topics: Diglycerides; Female; Glycerophospholipids; Humans; In Vitro Techniques; Kinetics; Myristic Acid; Myristic Acids; Phosphates; Phosphatidic Acids; Phosphatidylcholines; Phospholipids; Phosphorus Radioisotopes; Placenta; Pregnancy; Signal Transduction; Tetradecanoylphorbol Acetate; Tritium | 1996 |
Modulation of noninduced and phorbol ester-induced generation of superoxide anion by free liposomes and liposomes containing dexamethasone.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Calcium; Dexamethasone; Drug Carriers; Humans; Liposomes; Neutrophils; Phosphatidylcholines; Phosphatidylserines; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Influence of the protein kinase C inhibitor 3-[1-[3-(amidinothio) propyl]-1H-indoyl-3-yl]-3-(1-methyl-1H-indoyl-3-yl) maleimide methane sulfonate (Ro-318220) on surfactant secretion in type II pneumocytes.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Enzyme Inhibitors; Indoles; Lung; Male; Phosphatidylcholines; Protein Kinase C; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1997 |
Adenylate cyclase-coupled ATP receptor and surfactant secretion in type II pneumocytes from newborn rats.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Animals, Newborn; Cells, Cultured; Lung; Phosphatidylcholines; Pulmonary Surfactants; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Receptors, Purinergic P2; Signal Transduction; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 1997 |
Promotion-resistant JB6 mouse epidermal cells exhibit defects in phosphatidylethanolamine synthesis and phorbol ester-induced phosphatidylcholine hydrolysis.
Topics: Animals; Cell Line; Ethanolamine; Ethanolamines; Hydrolysis; Mice; Phorbol Esters; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Effects of a novel perfluorocarbon emulsion on neutrophil chemiluminescence in human whole blood in vitro.
Topics: Anions; Blood Substitutes; Emulsions; Fluorocarbons; Humans; Luminescent Measurements; Neutrophils; Phosphatidylcholines; Superoxides; Surface-Active Agents; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of lung surfactant secretion from alveolar type II cells and annexin II tetramer-mediated membrane fusion by phenothiazines.
Topics: Adenosine Triphosphate; Animals; Annexin A2; Bronchodilator Agents; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Liposomes; Male; Membrane Fusion; Phenothiazines; Phosphatidylcholines; Phospholipids; Promethazine; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Terbutaline; Tetradecanoylphorbol Acetate; Trifluoperazine | 1997 |
12-O-tetradecanoylphorbol-13-acetate inhibits aminophospholipid translocase activity and modifies the lateral motions of fluorescent phospholipid analogs in the plasma membrane of bovine aortic endothelial cells.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Aorta; Carcinogens; Carrier Proteins; Cattle; Cell Membrane; Cells, Cultured; Endothelium, Vascular; Fibroblast Growth Factor 2; Fluorescent Dyes; Lipid Bilayers; Membrane Proteins; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipid Transfer Proteins; Phospholipids; Tetradecanoylphorbol Acetate | 1997 |
1,2-Diacylglycerol hydroperoxides induce the generation and release of superoxide anion from human polymorphonuclear leukocytes.
Topics: Diglycerides; Humans; Imidazoles; Lipid Peroxides; Luminescent Measurements; Neutrophils; Phosphatidylcholines; Protein Kinase C; Pyrazines; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Differential activation of keratinocyte phospholipase A2S by tumor promoters and other irritants.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cytosol; Eicosanoids; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Fatty Acids; Isoenzymes; Keratinocytes; Membrane Lipids; Mice; Naphthalenes; Oligonucleotides, Antisense; Papilloma; Phosphatidylcholines; Phospholipases A; Phospholipids; Pyrones; Recombinant Fusion Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1997 |
Expression of protein kinase C-beta promotes the stimulatory effect of phorbol ester on phosphatidylethanolamine synthesis.
Topics: Animals; Blotting, Western; Cell Line; Enzyme Activation; Ethanolamine; Humans; Isoenzymes; Mice; Phosphatidylcholines; Phosphatidylethanolamines; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Rats; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1997 |
The generation of 1H-NMR-detectable mobile lipid in stimulated lymphocytes: relationship to cellular activation, the cell cycle, and phosphatidylcholine-specific phospholipase C.
Topics: Animals; Antibodies, Monoclonal; Bridged-Ring Compounds; CD3 Complex; Cell Cycle; Cell Division; Cell Survival; Drug Combinations; Ionomycin; Lipid Metabolism; Lipids; Lymphocyte Activation; Lymphocytes; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Norbornanes; Phosphatidylcholines; Receptors, Interleukin-2; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Thymus Gland; Type C Phospholipases; Up-Regulation | 1997 |
Extracellular sphingosine 1-phosphate stimulates formation of ethanolamine from phosphatidylethanolamine: modulation of sphingosine 1-phosphate-induced mitogenesis by ethanolamine.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; DNA; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Ethanolamine; Flavonoids; Gene Expression Regulation, Enzymologic; Hydrolysis; Insulin; Lysophospholipids; Mice; Mitogens; Mitosis; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Sphingosine; Tetradecanoylphorbol Acetate | 1997 |
Effects of brefeldin A on phosphatidylcholine phospholipase D and inositolphospholipid metabolism in HL-60 cells.
Topics: Adenosine Triphosphate; ADP-Ribosylation Factors; Brefeldin A; Cyclopentanes; Enzyme Activation; Enzyme Inhibitors; Galactosyltransferases; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Phosphatidylcholine-specific phospholipase C regulates thapsigargin-induced calcium influx in human lymphocytes.
Topics: Bridged-Ring Compounds; Butanols; Calcium; Enzyme Inhibitors; Estrenes; Humans; Indoles; Lymphocytes; Nickel; Norbornanes; Phosphatidylcholines; Phosphatidylinositols; Propranolol; Pyrrolidinones; Tetradecanoylphorbol Acetate; Thapsigargin; Thiocarbamates; Thiones; Type C Phospholipases | 1997 |
Involvement of phospholipase D and protein kinase C in phorbol ester and fatty acid stimulated turnover of phosphatidylcholine and phosphatidylethanolamine in neural cells.
Topics: Animals; Antineoplastic Agents; Bryostatins; Down-Regulation; Enzyme Activation; Fatty Acids; Humans; Lactones; Macrolides; Mice; Neuroglia; Neurons; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Metabolism of phosphatidylcholine in mouse pancreatic islets.
Topics: Adenosine Triphosphate; Aluminum Chloride; Aluminum Compounds; Animals; Calcimycin; Cells, Cultured; Chlorides; Choline; Colforsin; Glucose; Islets of Langerhans; Kinetics; Male; Mice; Mice, Inbred Strains; Phosphatidylcholines; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1997 |
Glucagon-like peptide-1-(7-36)amide increases pulmonary surfactant secretion through a cyclic adenosine 3',5'-monophosphate-dependent protein kinase mechanism in rat type II pneumocytes.
Topics: Adrenergic beta-Agonists; Animals; Calcimycin; Calcium-Transporting ATPases; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Lung; Male; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Wistar; Terbutaline; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Phorbol ester stimulation of phosphatidylcholine synthesis requires expression of both protein kinase C-alpha and phospholipase D.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Choline; Choline Kinase; Diglycerides; Enzyme Activation; Female; Humans; Isoenzymes; Mice; Phosphatidylcholines; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1998 |
Lecithinized superoxide dismutase attenuates phorbol myristate acetate-induced injury in isolated dog lung.
Topics: Animals; Capillary Permeability; Dogs; Drug Carriers; Drug Delivery Systems; Female; In Vitro Techniques; Leukocytes; Lung; Male; Neutrophils; Phosphatidylcholines; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1998 |
Overexpression of myristoylated alanine-rich C-kinase substrate enhances activation of phospholipase D by protein kinase C in SK-N-MC human neuroblastoma cells.
Topics: Calmodulin; Enzyme Activation; Gene Expression Regulation, Enzymologic; Glycerophospholipids; Golgi Apparatus; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Maleimides; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Neuroblastoma; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Protein Kinase C-alpha; Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Distinct phospholipase C-regulated signalling pathways in Swiss 3T3 fibroblasts induce the rapid generation of the same polyunsaturated diacylglycerols.
Topics: 3T3 Cells; Animals; Brain; Calcimycin; Calcium; Diglycerides; Dinoprost; Enzyme Activation; Fibroblasts; Ionophores; Mice; Phosphatidate Phosphatase; Phosphatidylcholines; Phospholipase D; Platelet-Derived Growth Factor; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Phospholipase D activity is altered in X-linked adrenoleukodystrophy heterozygous carriers, but not in hemizygous patients.
Topics: Carrier State; Cells, Cultured; Choline; Enzyme Activation; Female; Fibroblasts; Genetic Linkage; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Male; Membrane Proteins; Monosomy; Myristoylated Alanine-Rich C Kinase Substrate; Oleic Acid; Peroxisomal Disorders; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Proteins; Sex Chromosome Aberrations; Tetradecanoylphorbol Acetate; X Chromosome; Zellweger Syndrome | 1998 |
Origin of molecular species of diacylglycerol induced by bombesin in smooth muscle cells from rabbit rectosigmoid.
Topics: Animals; Bombesin; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Colon, Sigmoid; Diglycerides; Kinetics; Muscle Contraction; Muscle, Smooth; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Rabbits; Rectum; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Inhibition of lung surfactant secretion by KN-62, a specific inhibitor of the calcium- and calmodulin-dependent protein kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ionophores; Male; Phosphatidylcholines; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Terbutaline; Tetradecanoylphorbol Acetate | 1998 |
Phorbol ester-induced production of prostaglandin E2 from phosphatidylcholine through the activation of phospholipase D in UMR-106 cells.
Topics: Animals; Arachidonic Acid; Cell Line; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Glycerophospholipids; Lipoprotein Lipase; Myristic Acid; Osteoblasts; Phosphatidate Phosphatase; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Binding Sites; Cell Line; Chromones; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Morpholines; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphatidylserines; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Serine-Threonine Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1998 |
Osmotic stress induces both secretion and apoptosis in rat alveolar type II cells.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cells, Cultured; Choline; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Flavonoids; Isoenzymes; Kinetics; Male; Osmolar Concentration; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Signal Transduction; Sorbitol; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1998 |
The regulation of superoxide generation and nitric oxide synthesis by C-reactive protein.
Topics: Animals; Blotting, Western; Bridged-Ring Compounds; C-Reactive Protein; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Macrophages, Peritoneal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Time Factors | 1998 |
Choline derived from the phosphatidylcholine specific phospholipase D is not directly available for the CDP choline pathway in phorbol ester-treated C3H10T1/2 Cl 8 fibroblasts.
Topics: Animals; Cell Line; Choline; Cytidine Diphosphate Choline; Fibroblasts; Indoles; Maleimides; Mice; Mice, Inbred C3H; Phosphatidylcholines; Phospholipase D; Phosphorylcholine; Protein Kinase C; Tetradecanoylphorbol Acetate | 1998 |
Antagonistic roles for phospholipase D activities in B cell signaling: while the antigen receptors transduce mitogenic signals via a novel phospholipase D activity, phosphatidylcholine-phospholipase D mediates antiproliferative signals.
Topics: 1-Butanol; Adenosine Triphosphate; Animals; B-Lymphocytes; Cell Division; Cell Line; Diglycerides; DNA Replication; Humans; Hydrogen-Ion Concentration; Isoenzymes; Lipids; Lipopolysaccharides; Lymphocyte Activation; Lymphocyte Cooperation; Membrane Lipids; Mice; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Receptors, Antigen, B-Cell; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Regulation of lung surfactant secretion by phospholipase A2.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Cinnamates; Cyclohexanones; Diglycerides; Enzyme Inhibitors; Lipoprotein Lipase; Male; ortho-Aminobenzoates; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Terbutaline; Tetradecanoylphorbol Acetate | 1999 |
Overexpression of protein kinase C-epsilon and its regulatory domains in fibroblasts inhibits phorbol ester-induced phospholipase D activity.
Topics: 3T3 Cells; Animals; Blotting, Western; Fibroblasts; Gene Expression Regulation; Holoenzymes; Hydrolysis; Isoenzymes; Mice; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1999 |
Cellular responses to excess phospholipid.
Topics: Acylation; Choline-Phosphate Cytidylyltransferase; Doxycycline; Glycerylphosphorylcholine; HeLa Cells; Homeostasis; Humans; Naphthalenes; Phosphatidylcholines; Phosphatidylethanolamines; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Pyrones; Tetradecanoylphorbol Acetate | 1999 |
Anandamide stimulates phospholipase D activity in PC12 cells but not in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Arachidonic Acids; Cannabinoids; CHO Cells; Cricetinae; Endocannabinoids; Enzyme Activation; Humans; Hydrolysis; Mice; Nerve Growth Factors; PC12 Cells; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Polyunsaturated Alkamides; Rats; Tetradecanoylphorbol Acetate | 1999 |
Proteolysis of synaptobrevin, syntaxin, and SNAP-25 in alveolar epithelial type II cells.
Topics: Animals; Antigens, Surface; Blotting, Western; Calcimycin; Calpain; Epithelial Cells; Fluorescent Antibody Technique; Glycoproteins; Ionophores; Membrane Proteins; Nerve Tissue Proteins; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; R-SNARE Proteins; Rats; Secretory Rate; Synaptosomal-Associated Protein 25; Syntaxin 1; Tetradecanoylphorbol Acetate | 1999 |
Coordinate packaging of newly synthesized phosphatidylcholine and phosphatidylglycerol in lamellar bodies in alveolar type II cells.
Topics: Ammonium Chloride; Choline; Endoplasmic Reticulum; Hydrogen-Ion Concentration; Methylamines; Microsomes; Organelles; Palmitic Acid; Phosphatidylcholines; Phosphatidylglycerols; Pulmonary Alveoli; Pulmonary Surfactants; Tetradecanoylphorbol Acetate; Tritium | 2000 |
Involvement of PL-D in the alternate signal tranduction pathway of macrophages induced by an external stimulus.
Topics: Animals; Diglycerides; Enzyme Inhibitors; Hydrolysis; Macrophages; Mice; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Propranolol; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 2000 |
A novel fluorescent probe diphenyl-1-pyrenylphosphine to follow lipid peroxidation in cell membranes.
Topics: Animals; Cell Membrane; Female; Fluorescent Dyes; Free Radicals; Hydrogen Peroxide; Lipid Peroxidation; Lipid Peroxides; Liposomes; Mice; Mice, Inbred ICR; Microscopy, Fluorescence; Neutrophils; Organophosphorus Compounds; Oxidants; Oxidation-Reduction; Phosphatidylcholines; Pyrenes; Solutions; Spectrometry, Fluorescence; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate | 2000 |
Expression of a peptide binding to receptor for activated C-kinase (RACK1) inhibits phorbol myristoyl acetate-stimulated phospholipase D activity in C3H/10T1/2 cells: dissociation of phospholipase D-mediated phosphatidylcholine breakdown from its synthesi
Topics: 1-Butanol; Amino Acid Sequence; Animals; Carbon Radioisotopes; Choline; Enzyme Activation; Mice; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Receptors for Activated C Kinase; Tetradecanoylphorbol Acetate | 2000 |
Phosphatidylcholine metabolism in nuclei of phorbol ester-activated LA-N-1 neuroblastoma cells.
Topics: Carbon Radioisotopes; Cell Nucleus; Choline; Choline Kinase; Cytidine Diphosphate Choline; Humans; Kinetics; Neuroblastoma; Palmitic Acid; Phosphatidylcholines; Phosphorylcholine; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 2000 |
Cholecystokinin octapeptide CCK-8 and carbachol reduce [(32)P]orthophosphate labeling of phosphatidylcholine without modifying phospholipase D activity in rat pancreatic acini.
Topics: Animals; Butanols; Carbachol; Enzyme Activation; Ethanol; Glycerophospholipids; Hydrogen Peroxide; Kinetics; Pancreas; Phosphates; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Rats; Rats, Wistar; Sincalide; Tetradecanoylphorbol Acetate; Vanadates | 2000 |
Protein kinase C activation by 12-0-tetradecanoylphorbol 13-acetate in CG-4 line oligodendrocytes stimulates turnover of choline and ethanolamine phospholipids by phospholipase D and induces rapid process contraction.
Topics: Animals; Cell Line; Cell Surface Extensions; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Nocodazole; Oligodendroglia; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 2001 |
Resveratrol inhibits the formation of phosphatidic acid and diglyceride in chemotactic peptide- or phorbol ester-stimulated human neutrophils.
Topics: Choline; Chromatography, Thin Layer; Diglycerides; Drug Interactions; Ethanol; Ethanolamine; Glycerophosphates; Glycerophospholipids; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Interaction between beta-adrenergic signaling and protein kinase C increases cytoplasmic Ca2+ in alveolar type II cells.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium; Cells, Cultured; Cobalt; Colforsin; Cyclic AMP; Cytoplasm; Diglycerides; Drug Interactions; Epithelial Cells; Male; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Signal Transduction; Specific Pathogen-Free Organisms; Terbutaline; Tetradecanoylphorbol Acetate | 2001 |
Effects of liposomes of different phospholipid composition on the induction of respiratory burst in human blood monocytes and alveolar macrophages.
Topics: Arachidonic Acid; Calcimycin; Diglycerides; Fatty Acids; Humans; Ionophores; Liposomes; Macrophage Activation; Macrophages, Alveolar; Monocytes; NADPH Oxidases; Phosphatidylcholines; Phospholipids; Respiratory Burst; Tetradecanoylphorbol Acetate | 2001 |
Evidence for the involvement of the NADPH oxidase enzyme complex in the optimal accumulation of Platelet-activating factor in the human cell line PLB-985.
Topics: Calcimycin; Calcium; Cell Line; Gas Chromatography-Mass Spectrometry; Glycerylphosphorylcholine; Humans; Ionophores; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphatidylcholines; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Receptor-dependent metabolism of platelet-activating factor in murine macrophages.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Blotting, Western; Chromatography, Thin Layer; Concanavalin A; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genotype; Ligands; Lipid Metabolism; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Binding; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sucrose; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Dopamine D(2) receptor-induced COX-2-mediated production of prostaglandin E(2) in D(2)-transfected Chinese hamster ovary cells without simultaneous administration of a Ca(2+)-mobilizing agent.
Topics: Animals; Arachidonic Acids; Calcium; Calcium Channel Blockers; CHO Cells; Cricetinae; Cyclooxygenase 2; Dinoprostone; Dopamine; Dopamine Antagonists; Drug Interactions; Enzyme Inhibitors; Gallic Acid; Indomethacin; Isoenzymes; Naphthalenes; Nitrobenzenes; Phosphatidylcholines; Prostaglandin-Endoperoxide Synthases; Pyrones; Quinacrine; Receptors, Dopamine D2; Salicylamides; Salicylates; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 2002 |
Apolipoprotein-mediated cellular lipid release requires replenishment of sphingomyelin in a phosphatidylcholine-specific phospholipase C-dependent manner.
Topics: Acetates; Animals; Apolipoprotein A-I; Astrocytes; Bridged-Ring Compounds; Cell Line; Cells, Cultured; Ceramides; Cholesterol; Diglycerides; Glycerol; Humans; Mice; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Signal Transduction; Sphingomyelin Phosphodiesterase; Sphingomyelins; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Type C Phospholipases | 2002 |
The formation of phosphatidylcholine oxidation products by stimulated phagocytes.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Hydrogen Peroxide; Leukocytes, Mononuclear; Lipid Metabolism; Models, Chemical; Neutrophils; Oxidants; Oxygen; Phagocytes; Phagocytosis; Phosphatidylcholines; Spectrometry, Mass, Electrospray Ionization; Tetradecanoylphorbol Acetate | 2003 |
Control of the CDPethanolamine pathway in mammalian cells: effect of CTP:phosphoethanolamine cytidylyltransferase overexpression and the amount of intracellular diacylglycerol.
Topics: Animals; Cell Line, Tumor; CHO Cells; Choline; Cricetinae; Cytidine Diphosphate; Cytidine Triphosphate; Diglycerides; Ethanolamine; Ethanolamines; Humans; Liver; Nucleotidyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Rats; RNA Nucleotidyltransferases; Tetradecanoylphorbol Acetate; Transferases (Other Substituted Phosphate Groups); Type C Phospholipases | 2004 |
Transient in utero disruption of cystic fibrosis transmembrane conductance regulator causes phenotypic changes in alveolar type II cells in adult rats.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Calcium-Transporting ATPases; Cells, Cultured; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Knockdown Techniques; Lung; Male; Oligonucleotide Array Sequence Analysis; Phenotype; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein B; Rats; RNA, Antisense; Tetradecanoylphorbol Acetate | 2009 |
Reconstituted high-density lipoprotein suppresses leukocyte NADPH oxidase activation by disrupting lipid rafts.
Topics: Apolipoprotein A-I; beta-Cyclodextrins; Cell-Free System; Cholesterol; Endothelial Cells; Enzyme Activation; HL-60 Cells; Humans; Leukocytes; Lipoproteins, HDL; Luminescent Measurements; Membrane Lipids; Membrane Microdomains; NADPH Oxidases; Phagocytosis; Phosphatidylcholines; Superoxides; Tetradecanoylphorbol Acetate; Umbilical Veins; Xanthine; Xanthine Oxidase | 2009 |
Differential inhibitory effects of 2-azafluorenones on PI-PLC activation but not on PC-PLC- or PC-PLD-activation induced by histamine, PAF, PMA or A23187 in C6 glioma cells.
Topics: Animals; Calcimycin; Cell Line, Tumor; Enzyme Activation; Fluorenes; Histamine; Phosphatidylcholines; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phospholipase D; Platelet Activating Factor; Rats; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases | 2013 |
Ex Uno Plura: Differential Labeling of Phospholipid Biosynthetic Pathways with a Single Bioorthogonal Alcohol.
Topics: Alkynes; Arachis; Biotinylation; Choline; Chromatography, High Pressure Liquid; Click Chemistry; Fluorescent Dyes; HeLa Cells; Humans; Membrane Lipids; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Plant Proteins; Protein Isoforms; Substrate Specificity; Tetradecanoylphorbol Acetate | 2018 |
A novel ultradeformable liposomes of Naringin for anti-inflammatory therapy.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Cell Survival; Dermatitis; Drug Compounding; Female; Flavanones; Liposomes; Lysophosphatidylcholines; Mice; NIH 3T3 Cells; Phosphatidylcholines; Phosphatidylethanolamines; Skin; Skin Absorption; Tetradecanoylphorbol Acetate | 2018 |