phosphatidylcholines has been researched along with tetracaine in 45 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (tetracaine) | Trials (tetracaine) | Recent Studies (post-2010) (tetracaine) |
|---|---|---|---|---|---|
| 101 | 1 | 21 | 2,688 | 349 | 274 |
| 32,204 | 443 | 5,593 | 2,688 | 349 | 274 |
| Protein | Taxonomy | phosphatidylcholines (IC50) | tetracaine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 3.268 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 0.317 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 3.415 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 3.268 | |
| Sodium channel protein type 7 subunit alpha | Homo sapiens (human) | 0.056 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 0.5075 | |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | 1.4693 | |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | 0.795 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.673 | |
| Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | 0.74 | |
| Sodium channel protein type 8 subunit alpha | Homo sapiens (human) | 0.52 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (73.33) | 18.7374 |
| 1990's | 4 (8.89) | 18.2507 |
| 2000's | 3 (6.67) | 29.6817 |
| 2010's | 4 (8.89) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Conboy, JC; Nguyen, TT | 1 |
| Hendrickson, HS | 1 |
| Hendrickson, HS; van Dam-Mieras, MC | 1 |
| Akesson, B; Kanoh, H | 1 |
| Fujiwara, Y; Kuroda, Y; Nakagawa, T; Wakita, M | 1 |
| Bianconi, ML; do Amaral, AT; Schreier, S | 1 |
| Arnold, K; Barthel, D; Lange, K; Lenk, R; Zschoernig, O | 1 |
| Mason, RJ; Sano, K; Voelker, DR | 1 |
| Arnold, A; Mansbach, CM | 1 |
| Frezzatti, WA; Schreier, S; Toselli, WR | 1 |
| Poile, TW; Watts, A | 1 |
| Ferrell, JE; Huestis, WH; Mitchell, KT | 1 |
| Fujiwara, Y; Kuroda, Y | 1 |
| Boulanger, Y; Kelusky, EC; Schreier, S; Smith, IC | 1 |
| Cerbón, J | 1 |
| Gotterer, GS | 1 |
| Martonosi, A; Vanderkooi, JM | 1 |
| Ito, T; Onishi, S | 1 |
| Cerbón, J; Fernández, MS | 1 |
| Singer, MA | 1 |
| Oki, S | 1 |
| Chapman, D; Hauser, H; Penkett, SA | 1 |
| Bangham, AD; Miller, N; Standish, MM | 1 |
| Hersh, L | 1 |
| Boulanger, Y; Leitch, LC; Schreier, S; Smith, IC | 1 |
| Araujo, PS; Chaimovich, H; Cuccovia, IM; Frezzatti, WA; Schreier, S | 1 |
| Brown, MF; Jeffrey, KR; Siminovitch, DJ | 1 |
| Ohki, S | 1 |
| Kelusky, EC; Smith, IC | 1 |
| Boulanger, Y; Ehrenberg, A; Smith, IC; Westman, J | 1 |
| Fernández, MS | 2 |
| Jain, MK; Singer, MA | 1 |
| Baenziger, JE; Demers, CN; Méthot, N | 1 |
| Boedeker, BH; Haynes, DH; Kline, MD; Lojeski, EW | 1 |
| Ikawa, K; Shibata, A; Terada, H | 1 |
| FEINSTEIN, MB | 1 |
| Hutton, WC; Martin, RB; Yeagle, PL | 1 |
| Chander, J; Changez, M; Dinda, AK | 1 |
| Chander, J; Changez, M; Dinda, AK; Varshney, M | 1 |
| Baenziger, JE; daCosta, CJ; Goodreid, MM; Ryan, SE; Sturgeon, RM; Vuong, NQ | 1 |
| Ikonen, M; Kontturi, K; Murtomäki, L | 1 |
| Bandeiras, C; Fernandes, A; Luzyanin, K; Saramago, B; Serro, AP | 1 |
| Cremer, PS; Huang, D; Xu, W; Yang, T; Zhao, T | 1 |
| Cheng, D; Hu, S; Li, H; Sun, Z; Zhao, T | 1 |
45 other study(ies) available for phosphatidylcholines and tetracaine
| Article | Year |
|---|---|
High-throughput screening of drug-lipid membrane interactions via counter-propagating second harmonic generation imaging.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Dimyristoylphosphatidylcholine; High-Throughput Screening Assays; Lipid Bilayers; Phosphatidylcholines; Tetracaine; Thermodynamics | 2011 |
The penetration of local anesthetics into phosphatidylcholine monolayers.
Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Biological Transport; Dibucaine; Kinetics; Lidocaine; Membranes, Artificial; Models, Biological; Permeability; Phosphatidylcholines; Procaine; Structure-Activity Relationship; Tetracaine; Triglycerides | 1976 |
Local anesthetic inhibition of pancreatic phospholipase A2 action on lecithin monolayers.
Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Calcium; Dibucaine; Kinetics; Lidocaine; Membranes, Artificial; Models, Biological; Pancreas; Phosphatidylcholines; Phospholipases; Procaine; Spectrophotometry, Ultraviolet; Surface Properties; Tetracaine | 1976 |
Phospholipid degradation in isolated rat hepatocytes. Metabolism of intracellularly formed dilinoleoyl-dipalmitoyl- and dimyristoylglycerophosphocholine.
Topics: Animals; Glycerol; In Vitro Techniques; Kinetics; Linoleic Acids; Liver; Male; Myristic Acids; Oleic Acids; Palmitic Acids; Phosphatidylcholines; Phospholipases; Rats; Tetracaine | 1977 |
Conformations of dibucaine and tetracaine in small unilamellar phosphatidylcholine vesicles as studied by nuclear Overhauser effects in 1H nuclear magnetic resonance spectroscopy.
Topics: Dibucaine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Phosphatidylcholines; Tetracaine | 1992 |
Use of membrane spin label spectra to monitor rates of reaction of partitioning compounds: hydrolysis of a local anesthetic analog.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Hydrolysis; Lipid Bilayers; Liposomes; Phosphatidylcholines; Spectrophotometry; Spin Labels; Tetracaine | 1988 |
Interaction of electrically charged drug molecules with phospholipid membranes.
Topics: Alprenolol; Chlorpromazine; Electrophoresis; Liposomes; Membrane Lipids; Pharmaceutical Preparations; Phosphatidylcholines; Propanolamines; Propranolol; Solubility; Surface Properties; Tetracaine | 1988 |
Involvement of protein kinase C in pulmonary surfactant secretion from alveolar type II cells.
Topics: Animals; Cyclic AMP; Cytosol; Diglycerides; Drug Interactions; Phosphatidylcholines; Protein Kinase C; Protein Kinases; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Terbutaline; Tetracaine; Tetradecanoylphorbol Acetate | 1985 |
CTP:phosphocholine cytidylyltransferase in intestinal mucosa.
Topics: Animals; Bile; Chlorpromazine; Choline-Phosphate Cytidylyltransferase; Cytosol; Enzyme Activation; In Vitro Techniques; Intestinal Mucosa; Male; Microsomes; Nucleotidyltransferases; Phosphatidylcholines; Phospholipids; Propranolol; Rats; Rats, Inbred Strains; Solubility; Specimen Handling; Tetracaine; Triglycerides | 1986 |
Spin label study of local anesthetic-lipid membrane interactions. Phase separation of the uncharged form and bilayer micellization by the charged form of tetracaine.
Topics: Anesthetics, Local; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Micelles; Phosphatidylcholines; Spin Labels; Tetracaine | 1986 |
Direct determination by 2H-NMR of the ionization state of phospholipids and of a local anaesthetic at the membrane surface.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Membrane Lipids; Phosphatidylcholines; Phosphatidylethanolamines; Protons; Tetracaine | 1986 |
Membrane bilayer balance and platelet shape: morphological and biochemical responses to amphipathic compounds.
Topics: Adult; Anions; Blood Platelets; Cations; Cell Membrane; Chlorpromazine; Dibucaine; Dimyristoylphosphatidylcholine; Erythrocytes; Humans; Lipid Bilayers; Membrane Lipids; Membrane Proteins; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylserines; Phosphorylation; Platelet Activating Factor; Tetracaine; Thrombin | 1988 |
Locations and dynamical perturbations for lipids of cationic forms of procaine, tetracaine, and dibucaine in small unilamellar phosphatidylcholine vesicles as studied by nuclear Overhauser effects in 1H nuclear magnetic resonance spectroscopy.
Topics: Cations; Chemical Phenomena; Chemistry; Dibucaine; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Membrane Fluidity; Membrane Lipids; Phosphatidylcholines; Procaine; Structure-Activity Relationship; Tetracaine | 1987 |
A 2H-NMR study on the interactions of the local anesthetic tetracaine with membranes containing phosphatidylserine.
Topics: Deuterium; Hydrogen-Ion Concentration; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylserines; Solubility; Tetracaine | 1986 |
NMR evidence for the hydrophobic interaction of local anaesthetics. Possible relation to their potency.
Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Animals; Brain; Calcium; Cattle; Dibucaine; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Membranes, Artificial; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Procaine; Structure-Activity Relationship; Surface Properties; Tetracaine; Time Factors; Vibration | 1972 |
Rat liver D-beta-hydroxybutyrate dehydrogenase. 3. Inhibition by topical anesthetics.
Topics: Acetoacetates; Alcohols; Anesthetics, Local; Animals; Dibucaine; Hydroxybutyrate Dehydrogenase; Kinetics; Lipids; Liver; Mitochondria, Liver; NAD; Phosphatidylcholines; Propranolol; Quinine; Rats; Solubility; Tetracaine | 1969 |
Sarcoplasmic reticulum. XII. The interaction of 8-anilino-1-naphthalene sulfonate with skeletal muscle microsomes.
Topics: Acetone; Aniline Compounds; Animals; Binding Sites; Calcium Chloride; Chlorides; Chloroform; Fluorescence; Lanthanum; Lidocaine; Lysophosphatidylcholines; Magnesium; Mathematics; Membranes; Methanol; Microsomes; Muscle Proteins; Muscles; Naphthalenes; Phosphatidylcholines; Phospholipases; Phospholipids; Polymyxins; Procaine; Rabbits; Rotation; Sarcoplasmic Reticulum; Serum Albumin; Sucrose; Sulfonic Acids; Temperature; Tetracaine; Viscosity | 1971 |
Calcium-induced phase separations in phosphatidylserine--phosphatidylcholine membranes.
Topics: Animals; Bacteria; Barium; Brain; Calcium; Cardiolipins; Cattle; Cell Adhesion; Chelating Agents; Chemical Phenomena; Chemistry; Cyclic N-Oxides; Egg Yolk; Electron Spin Resonance Spectroscopy; Female; Magnesium; Membranes, Artificial; Micropore Filters; Nervous System Physiological Phenomena; Oxazoles; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Plants; Strontium; Structure-Activity Relationship; Surface Properties; Tetracaine | 1974 |
The importance of the hydrophobic interactions of local anesthetics in the displacement of polyvalent cations from artificial lipid membranes.
Topics: Anesthetics, Local; Deuterium; Europium; Lidocaine; Liposomes; Magnetic Resonance Spectroscopy; Membranes, Artificial; Phosphatidylcholines; Praseodymium; Procaine; Quaternary Ammonium Compounds; Tetracaine; Vibration | 1973 |
Interaction of local anesthetics and salicylate with phospholipid membranes.
Topics: Anesthetics, Local; Calcium Chloride; Dibucaine; Electrophoresis; Liposomes; Membranes, Artificial; Phosphatidylcholines; Phospholipids; Salicylates; Sodium Isotopes; Surface Properties; Tetracaine | 1973 |
Effect of local anesthetics on phospholipid bilayers.
Topics: Anesthetics, Local; Animals; Anura; Calcium; Cocaine; Dibucaine; Electricity; Electrophysiology; In Vitro Techniques; Membranes, Artificial; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Procaine; Sciatic Nerve; Tetracaine | 1970 |
Nuclear magnetic resonance spectroscopic studies of procaine hydrochloride and tetracaine hydrochloride at lipid-water interfaces.
Topics: Hydrochloric Acid; Kinetics; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Procaine; Surface Properties; Tetracaine; Vibration; Water | 1969 |
Cation permeability of phospholipid model membranes: effect of narcotics.
Topics: Alcohols; Cell Membrane Permeability; Chloroform; Cocaine; Dibucaine; Ethyl Ethers; Models, Theoretical; Phosphatidylcholines; Procaine; Tetracaine | 1965 |
The interaction of local anesthetics with lecithin monolayers.
Topics: Anesthetics, Local; Dibucaine; Ephedrine; Phosphatidylcholines; Procaine; Quinine; Surface Tension; Tetracaine | 1967 |
Multiple binding sites for local anesthetics in membranes: characterization of the sites and their equilibria by deuterium NMR of specifically deuterated procaine and tetracaine.
Topics: Deuterium; Electron Spin Resonance Spectroscopy; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; Procaine; Structure-Activity Relationship; Tetracaine | 1980 |
Effect of lipid membranes on the apparent pK of the local anesthetic tetracaine. Spin label and titration studies.
Topics: Electron Spin Resonance Spectroscopy; Ions; Membrane Lipids; Phosphatidylcholines; Solubility; Tetracaine | 1984 |
14N NMR of lipid bilayers: effects of ions and anesthetics.
Topics: Anions; Cations; Chemical Phenomena; Chemistry; Lipid Bilayers; Magnetic Resonance Spectroscopy; Metals, Rare Earth; Models, Biological; Molecular Conformation; Phosphatidylcholines; Tetracaine | 1984 |
Adsorption of local anesthetics on phospholipid membranes.
Topics: Adsorption; Anesthetics, Local; Dibucaine; Electrophoresis; Liposomes; Phosphatidylcholines; Phosphatidylserines; Procaine; Tetracaine | 1984 |
Anesthetic-membrane interaction: a 2H nuclear magnetic resonance study of the binding of specifically deuterated tetracaine and procaine to phosphatidylcholine.
Topics: Chemical Phenomena; Chemistry, Physical; Cold Temperature; Deuterium; Freezing; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Membrane Lipids; Membranes, Artificial; Phosphatidylcholines; Procaine; Tetracaine | 1984 |
Charge and pH dependent drug binding to model membranes. A 2H-NMR and light absorption study.
Topics: Animals; Cattle; Chickens; Egg Yolk; Female; Freezing; Hydrogen-Ion Concentration; Lipid Bilayers; Magnetic Resonance Spectroscopy; Mathematics; Phosphatidylcholines; Phosphatidylserines; Procaine; Structure-Activity Relationship; Tetracaine | 1982 |
Disruption of liposomes by tetracaine micelles.
Topics: Chromatography, Thin Layer; Colloids; Filtration; Light; Liposomes; Micelles; Phosphatidylcholines; Scattering, Radiation; Tetracaine | 1981 |
Formation of micelles and membrane action of the local anesthetic tetracaine hydrochloride.
Topics: Anilino Naphthalenesulfonates; Colloids; Kinetics; Liposomes; Micelles; Perylene; Phosphatidylcholines; Tetracaine | 1980 |
Interaction of four local anesthetics with phospholipid bilayer membranes: permeability effects and possible mechanisms.
Topics: Anesthetics, Local; Benzocaine; Chemical Phenomena; Chemistry; Dibucaine; Kinetics; Lipid Bilayers; Phosphatidylcholines; Procaine; Sodium; Structure-Activity Relationship; Temperature; Tetracaine | 1980 |
Structure of both the ligand- and lipid-dependent channel-inactive states of the nicotinic acetylcholine receptor probed by FTIR spectroscopy and hydrogen exchange.
Topics: Animals; Carbachol; Cholesterol; Deuterium; Hydrogen; Hydrogen Bonding; Ion Channels; Lipid Bilayers; Membrane Lipids; Phosphatidic Acids; Phosphatidylcholines; Protein Structure, Secondary; Receptors, Nicotinic; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Tetracaine; Torpedo | 1995 |
Ultra-long-duration local anesthesia produced by injection of lecithin-coated tetracaine microcrystals.
Topics: Anesthetics, Local; Animals; Capsules; Male; Pain Measurement; Particle Size; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Tetracaine | 1994 |
Site of action of the local anesthetic tetracaine in a phosphatidylcholine bilayer with incorporated cardiolipin.
Topics: Animals; Binding Sites; Biophysical Phenomena; Biophysics; Cardiolipins; Cattle; Esters; Hydrogen-Ion Concentration; In Vitro Techniques; Lipid Bilayers; Molecular Structure; Phosphates; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared; Tetracaine; Water | 1995 |
REACTION OF LOCAL ANESTHETICS WITH PHOSPHOLIPIDS. A POSSIBLE CHEMICAL BASIS FOR ANESTHESIA.
Topics: Alcohols; Aminobenzoates; Anesthesia; Anesthesia, Local; Anesthetics, Local; Biological Transport; Calcium; Chemical Phenomena; Chemistry; Chloroform; Cholesterol; Hydrogen-Ion Concentration; Ions; Lecithins; Lipids; Methanol; para-Aminobenzoates; Pharmacology; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Potassium; Procaine; Rabbits; Research; Sodium; Tetracaine | 1964 |
Molecular dynamics of the local anesthetic tetracaine in phospholipid vesicles.
Topics: Anesthetics, Local; Animals; Biophysics; Cations; Chromatography; Lipid Bilayers; Magnetic Resonance Spectroscopy; Ovum; Phosphatidylcholines; Quaternary Ammonium Compounds; Tetracaine; Time Factors; Water | 1977 |
Transdermal permeation of tetracaine hydrochloride by lecithin microemulsion: in vivo.
Topics: 1-Propanol; Administration, Cutaneous; Anesthetics, Local; Animals; Catalase; Drug Carriers; Emulsions; Lipid Peroxidation; Male; Malondialdehyde; Mice; Microscopy, Confocal; Myristates; Pain; Permeability; Phosphatidylcholines; Proteins; Rats; Rats, Wistar; Skin; Skin Irritancy Tests; Solvents; Subcellular Fractions; Tetracaine; Water | 2006 |
Effect of the composition of lecithin/n-propanol/isopropyl myristate/water microemulsions on barrier properties of mice skin for transdermal permeation of tetracaine hydrochloride: in vitro.
Topics: 1-Propanol; Administration, Cutaneous; Anesthetics, Local; Animals; Biological Transport; Calorimetry, Differential Scanning; Cell Membrane Permeability; Drug Carriers; Emulsions; Male; Mice; Microchemistry; Microscopy, Confocal; Microscopy, Electron, Transmission; Molecular Structure; Myristates; Phosphatidylcholines; Skin; Tetracaine; Water | 2006 |
Lipid composition alters drug action at the nicotinic acetylcholine receptor.
Topics: Anesthetics, Local; Animals; Cholesterol; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Kinetics; Lipid Bilayers; Lipids; Phosphatidic Acids; Phosphatidylcholines; Protein Conformation; Receptors, Nicotinic; Spectroscopy, Fourier Transform Infrared; Tetracaine; Torpedo | 2008 |
Microcalorimetric and zeta potential study on binding of drugs on liposomes.
Topics: Algorithms; Alprenolol; Binding Sites; Binding, Competitive; Calorimetry; Entropy; Kinetics; Labetalol; Liposomes; Models, Chemical; Molecular Structure; Pharmaceutical Preparations; Phosphatidylcholines; Phosphatidylglycerols; Propranolol; Tetracaine; Thermodynamics | 2010 |
Anesthetics interacting with lipid rafts.
Topics: Anesthetics; Cholesterol; Lidocaine; Lipid Bilayers; Liposomes; Membrane Microdomains; Phosphatidylcholines; Propofol; Sphingomyelins; Tetracaine | 2013 |
Sensing small molecule interactions with lipid membranes by local pH modulation.
Topics: Cholesterol; Hydrogen-Ion Concentration; Lipid Bilayers; Membranes, Artificial; Microscopy, Fluorescence; Phosphatidylcholines; Tetracaine | 2013 |
Effect of tetracaine on dynamic reorganization of lipid membranes.
Topics: Biophysical Phenomena; Cholesterol; Lipid Bilayers; Lipid Metabolism; Membrane Lipids; Phosphatidylcholines; Tetracaine | 2020 |