phosphatidylcholines has been researched along with staurosporine in 33 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (staurosporine) | Trials (staurosporine) | Recent Studies (post-2010) (staurosporine) |
|---|---|---|---|---|---|
| 32,204 | 443 | 5,593 | 6,272 | 58 | 976 |
| Protein | Taxonomy | phosphatidylcholines (IC50) | staurosporine (IC50) |
|---|---|---|---|
| Chain A, Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | 0.0003 | |
| Chain X, Tyrosine-protein kinase Lyn | Homo sapiens (human) | 0.0013 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.03) | 18.7374 |
| 1990's | 29 (87.88) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 1 (3.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujinami, H; Izawa, T; Komabayashi, T; Suda, K; Tsuboi, M; Yakata, A | 1 |
| Fung, WJ; Gilfillan, AM; Lin, P | 1 |
| Izawa, T; Komabayashi, T; Noguchi, M; Suda, K; Tsuboi, M; Yakata, A | 2 |
| Crichton, CA; Currie, S; Hallam, C; Jackson, CG; Smith, GL; Wakelam, MJ | 1 |
| Cockcroft, S; Geny, B | 1 |
| Kasuga, M; Konda, Y; Matozaki, T; Matsuda, K; Nagao, M; Nakano, O; Nishisaki, H; Sakamoto, C; Suzuki, T; Wada, K | 1 |
| Bahrami, LH; Lenhard, LW; Pandol, SJ; Perkins, PS | 1 |
| de Widt, J; Hilkmann, H; van Blitterswijk, WJ; van der Bend, RL | 1 |
| Feldman, DR; Martin, TW; Michaelis, KC | 1 |
| August, J; Bishop, WR; Pai, JK; Petrin, JM | 1 |
| Cabot, MC; Cao, HT; Welsh, CJ; Zhang, ZC | 1 |
| Halstead, J; Ignotz, RA; Kemp, K | 1 |
| Ito, Y; Kotoyori, J; Kozawa, O; Oiso, Y; Suzuki, A; Tokuda, H; Watanabe, Y | 1 |
| Anderson, WH; Kiss, Z | 2 |
| Foster, DA; Jiang, YW; Song, J | 1 |
| Kiss, Z | 1 |
| Chander, A; Sen, N | 1 |
| Carnero, A; Lacal, JC | 1 |
| Izawa, T; Komabayashi, T; Noguchi, M; Suda, K; Tsuboi, M | 1 |
| Cabot, MC; Huang, C; Wykle, RL | 1 |
| Kozawa, O; Oiso, Y; Saito, H; Shinoda, J; Suzuki, A; Watanabe, Y | 1 |
| Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A | 2 |
| Byers, DM; Cook, HW; Mandla, SG; Ridgway, ND | 1 |
| Collyn, L; Dumont, JE; Lejeune, C; Mockel, J; Rocmans, P; Taton, M | 1 |
| Igata, A; Imamura, Y; Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A; Tokuda, H; Watanabe-Tomita, Y | 1 |
| Edington, J; Gottesman, SR; Swenson, CD; Thorbecke, GJ; Xue, B | 1 |
| Malaquias, AT; Oliveira, MM | 1 |
| Cheung, GT; Frohlich, J; Lynn, EG; O, K; Siow, YL | 1 |
| Abrahão, A; Castro, P; Fuly, AL; Guimarães, JA; Koatz, VL; Lopes, UG; Machado, AL; Redner, P | 1 |
| Hirashima, N; Nishimura, Y; Tadokoro, S; Tanaka, M | 1 |
33 other study(ies) available for phosphatidylcholines and staurosporine
| Article | Year |
|---|---|
Mechanism of carbachol-stimulated diacylglycerol formation in rat parotid acinar cells.
Topics: Alkaloids; Animals; Carbachol; Choline; Diglycerides; In Vitro Techniques; Male; Parotid Gland; Phosphatidylcholines; Phosphatidylinositols; Propranolol; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Sulfonamides | 1992 |
Phosphatidylcholine-specific phospholipase D-derived 1,2-diacylglycerol does not initiate protein kinase C activation in the RBL 2H3 mast-cell line.
Topics: Alkaloids; Animals; Cell Compartmentation; Diglycerides; Enzyme Activation; Ethanol; Histamine Release; In Vitro Techniques; Mast Cells; Phosphatidylcholines; Phospholipase D; Propranolol; Protein Kinase C; Rats; Receptors, IgE; Signal Transduction; Staurosporine; Tumor Cells, Cultured | 1992 |
Ca2+ ionophore and phorbol ester stimulate diacylglycerol formation and phosphatidylcholine hydrolysis in rat parotid acinar cells.
Topics: Alkaloids; Animals; Calcimycin; Choline; Diglycerides; Dose-Response Relationship, Drug; Ethanolamine; Ethanolamines; Hydrolysis; Male; Parotid Gland; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Rats; Rats, Inbred Strains; Staurosporine | 1992 |
Bombesin stimulates the rapid activation of phospholipase A2-catalyzed phosphatidylcholine hydrolysis in Swiss 3T3 cells.
Topics: 3T3 Cells; Alkaloids; Animals; Arachidonic Acid; Bombesin; Calcium; Calcium-Transporting ATPases; Carbon Radioisotopes; Dose-Response Relationship, Drug; Enzyme Activation; Hydrolysis; Kinetics; Lysophosphatidylcholines; Mice; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phospholipids; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Synergistic activation of phospholipase D by protein kinase C- and G-protein-mediated pathways in streptolysin O-permeabilized HL60 cells.
Topics: Adenosine Triphosphate; Alkaloids; Bacterial Proteins; Cell Line; Cell Membrane Permeability; Drug Synergism; Enzyme Activation; Glycerophospholipids; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Neomycin; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Staurosporine; Streptolysins; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Cholecystokinin inhibits phosphatidylcholine synthesis via a Ca(2+)-calmodulin-dependent pathway in isolated rat pancreatic acini. A possible mechanism for diacylglycerol accumulation.
Topics: Alkaloids; Animals; Bombesin; Bucladesine; Calcimycin; Calcium; Calmodulin; Carbachol; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Diglycerides; In Vitro Techniques; Kinetics; Male; Nucleotidyltransferases; Pancreas; Phosphatidylcholines; Protein Kinase C; Rats; Rats, Inbred Strains; Secretin; Sincalide; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tritium | 1991 |
Intracellular mechanisms involved in short-term regulation of net protein synthesis in pancreatic acini.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amylases; Animals; Calcimycin; Carbachol; DNA Probes; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzymes; Isoquinolines; Lipase; Nucleic Acid Hybridization; Pancreas; Pancreatic Elastase; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Substance P-induced diacylglycerol formation in rat parotid acinar cells.
Topics: Alkaloids; Animals; Cells, Cultured; Choline; Diglycerides; Ethanolamine; Ethanolamines; Hydrolysis; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Parotid Gland; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorus Radioisotopes; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Stimulation, Chemical; Substance P; Tritium | 1991 |
Phospholipid metabolism in bradykinin-stimulated human fibroblasts. I. Biphasic formation of diacylglycerol from phosphatidylinositol and phosphatidylcholine, controlled by protein kinase C.
Topics: Alkaloids; Bradykinin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diglycerides; Down-Regulation; Fibroblasts; Glyceryl Ethers; Humans; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Phosphatidylcholine hydrolysis stimulated by phorbol myristate acetate is mediated principally by phospholipase D in endothelial cells.
Topics: Alkaloids; Animals; Cattle; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Ethanol; Hydrolysis; Kinetics; Phosphatidylcholines; Phospholipase D; Phospholipases; Pulmonary Artery; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Regulation of sn-1,2-diacylglycerol second-messenger formation in thrombin-stimulated human platelets. Potentiation by protein kinase C inhibitors.
Topics: Alkaloids; Blood Platelets; Carbazoles; Diglycerides; Drug Synergism; Enzyme Activation; Feedback; Glycerides; Humans; Indole Alkaloids; Neomycin; Phosphatidic Acids; Phosphatidylcholines; Phosphorylation; Propranolol; Protein Kinase C; Second Messenger Systems; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Evidence for a protein kinase C-directed mechanism in the phorbol diester-induced phospholipase D pathway of diacylglycerol generation from phosphatidylcholine.
Topics: Alkaloids; Animals; Bucladesine; Cell Line; Choline; Colforsin; Diglycerides; Embryo, Mammalian; Fibroblasts; Glycerides; Glycerophospholipids; Hydrolysis; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Evidence for involvement of phosphatidylcholine-phospholipase C and protein kinase C in transforming growth factor-beta signaling.
Topics: Alkaloids; Bridged-Ring Compounds; GTP-Binding Proteins; Humans; Norbornanes; Phosphatidylcholines; Plasminogen Activator Inhibitor 1; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Transforming Growth Factor beta; Tumor Cells, Cultured; Type C Phospholipases | 1995 |
Prostaglandin F2 alpha activates phospholipase D independently from activation of protein kinase C in osteoblast-like cells.
Topics: Alkaloids; Cell Line; Choline; Dinoprost; Enzyme Activation; GTP-Binding Proteins; Hydrolysis; Osteoblasts; Pertussis Toxin; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1994 |
Selective down-regulation of protein kinase c-epsilon by carcinogens does not prevent stimulation of phospholipase D by phorbol ester and platelet-derived growth factor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Benzo(a)pyrene; Carcinogens; Cell Line; Isoenzymes; Mice; Mice, Inbred C3H; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Platelet-Derived Growth Factor; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Epidermal growth factor induces the production of biologically distinguishable diglyceride species from phosphatidylinositol and phosphatidylcholine via the independent activation of type C and type D phospholipases.
Topics: Alkaloids; Animals; Cell Line; Diglycerides; Epidermal Growth Factor; Humans; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Time Factors; Type C Phospholipases | 1994 |
The zinc chelator 1,10-phenanthroline enhances the stimulatory effects of protein kinase C activators and staurosporine, but not sphingosine and H2O2, on phospholipase D activity in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Alkaloids; Animals; Chelating Agents; Enzyme Activation; Hydrogen Peroxide; Hydrolysis; Mice; Phenanthrolines; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Zinc | 1994 |
Alkalosis- and ATP-induced increases in the diacyglycerol pool in alveolar type II cells are derived from phosphatidylcholine and phosphatidylinositol.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Carbon Dioxide; Cells, Cultured; Diglycerides; Enzyme Activation; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Male; Phosphatidylcholines; Phosphatidylinositols; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Staurosporine; Type C Phospholipases | 1994 |
Hydrogen peroxide regulates phospholipase D-mediated hydrolysis of phosphatidylethanolamine and phosphatidylcholine by different mechanisms in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Alkaloids; Animals; Fibroblasts; Hydrogen Peroxide; Hydrolysis; Kinetics; Mice; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Sphingosine; Staurosporine; Substrate Specificity; Tetradecanoylphorbol Acetate | 1994 |
Phospholipase-induced maturation of Xenopus laevis oocytes: mitogenic activity of generated metabolites.
Topics: Alkaloids; Animals; Diglycerides; Indoles; Maleimides; Microinjections; Mitosis; Oocytes; Peptide Fragments; Phosphatidylcholines; Phosphatidylinositols; Phospholipases; Protein Kinase C; Signal Transduction; Staurosporine; Xenopus laevis | 1993 |
Mechanism of isoprenaline-stimulated diacylglycerol formation in rat parotid acinar cells.
Topics: Alkaloids; Animals; Bucladesine; Cells, Cultured; Colforsin; Diglycerides; In Vitro Techniques; Isoproterenol; Kinetics; Male; Parotid Gland; Phentolamine; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Propranolol; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Staurosporine; Stimulation, Chemical; Vasoactive Intestinal Peptide | 1993 |
Comparison of phospholipase D activity in vasopressin- and phorbol ester-stimulated fibroblasts.
Topics: Alkaloids; Calcium; Cell Line; Enzyme Activation; Fibroblasts; Glycerol; Glycerophospholipids; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1993 |
Thrombin induces proliferation of osteoblast-like cells through phosphatidylcholine hydrolysis.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Calcium; Cell Division; Choline; Enzyme Inhibitors; GTP-Binding Proteins; Inositol Phosphates; Mice; Osteoblasts; Phosphatidylcholines; Phospholipase D; Phosphorylcholine; Propranolol; Protein Kinase C; Signal Transduction; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1996 |
Tyrosine kinase is involved in angiotensin II-stimulated phospholipase D activation in aortic smooth muscle cells: function of Ca2+ influx.
Topics: Alkaloids; Angiotensin II; Animals; Aorta; Biological Transport; Calcimycin; Calcium; Cells, Cultured; Choline; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Genistein; Inositol Phosphates; Ionophores; Isoflavones; Membrane Lipids; Muscle Proteins; Muscle, Smooth, Vascular; Phosphatidylcholines; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phosphoric Diester Hydrolases; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Differential alterations of ethanolamine and choline phosphoglyceride metabolism by clofibrate and retinoic acid in human fibroblasts are not mediated by phorbol ester-sensitive protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinogens; Clofibrate; Enzyme Inhibitors; Ethanolamine; Ethanolamines; Fibroblasts; Humans; Hypolipidemic Agents; Isoquinolines; Phosphatidylcholines; Phospholipids; Protein Kinase C; Skin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1996 |
Regulation and metabolic role of phospholipase D activity in human thyroid and cultured dog thyrocytes.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium-Transporting ATPases; Cells, Cultured; Cytidine Monophosphate; Dogs; Enzyme Inhibitors; Glycerophospholipids; Humans; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Staurosporine; Thapsigargin; Thyroid Gland; Thyrotropin; Tritium | 1996 |
Function of Ca2+ in phosphatidylcholine-hydrolyzing phospholipase D activation in osteoblast-like cells.
Topics: 3T3 Cells; Animals; Calcium; Calcium Channel Blockers; Choline; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; Imidazoles; Mice; Osteoblasts; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Involvement of phosphatidylcholine hydrolysis by phospholipase D in extracellular ATP-induced arachidonic acid release in aortic smooth muscle cells.
Topics: Adenosine Triphosphate; Animals; Aorta; Arachidonic Acid; Cells, Cultured; Choline; Enzyme Inhibitors; Extracellular Space; Hydrolysis; Male; Muscle, Smooth, Vascular; Phosphatidylcholines; Phospholipase D; Rats; Rats, Sprague-Dawley; Staurosporine | 1997 |
The effect of aging on the immune response: influence of phosphatidylcholine-containing lipid on IgD-receptor expression and antibody formation.
Topics: Aging; Animals; Antibody Formation; Cross-Sectional Studies; Drug Administration Routes; Humans; Immunoglobulin D; In Vitro Techniques; Membrane Fluidity; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Phosphatidylcholines; Receptors, Fc; Staurosporine; T-Lymphocytes; Tissue Transplantation; Tumor Cells, Cultured; Up-Regulation | 1997 |
Phospholipid signalling pathways in Trypanosoma cruzi growth control.
Topics: Adenylate Cyclase Toxin; Animals; Benzylamines; Carbazoles; Cell Division; Culture Media; Cyclic AMP; Dose-Response Relationship, Drug; Estrenes; Indoles; Lysophospholipids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Protein Kinases; Pyrroles; Pyrrolidinones; Signal Transduction; Sphingosine; Staurosporine; Sulfonamides; Trypanosoma cruzi; Type C Phospholipases; Virulence Factors, Bordetella | 1999 |
Lipoprotein-X stimulates monocyte chemoattractant protein-1 expression in mesangial cells via nuclear factor-kappa B.
Topics: Amino Acid Sequence; Animals; Calcium Channel Blockers; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Cholesterol; Diglycerides; Diltiazem; Enzyme Inhibitors; Foam Cells; Gene Expression; Genes, Recessive; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Humans; Indoles; Lecithin Cholesterol Acyltransferase Deficiency; Lipoprotein-X; Male; Molecular Sequence Data; Monocytes; NF-kappa B; Phosphatidylcholines; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Type C Phospholipases | 2001 |
Lysophosphatidylcholine produced by the phospholipase A2 isolated from Lachesis muta snake venom modulates natural killer activity as a protein kinase C effector.
Topics: Animals; Cell Line, Tumor; Crotalid Venoms; Humans; Killer Cells, Natural; Lysophosphatidylcholines; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Isoforms; Protein Kinase C; Staurosporine; Viperidae | 2007 |
Detection of asymmetric distribution of phospholipids by fluorescence resonance energy transfer.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Apoptosis; CHO Cells; Cricetinae; ErbB Receptors; Fluorescence Resonance Energy Transfer; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Staurosporine | 2012 |