phosphatidylcholines has been researched along with sphingosine in 91 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (sphingosine) | Trials (sphingosine) | Recent Studies (post-2010) (sphingosine) |
|---|---|---|---|---|---|
| 32,204 | 443 | 5,593 | 8,325 | 117 | 3,459 |
| Protein | Taxonomy | phosphatidylcholines (IC50) | sphingosine (IC50) |
|---|---|---|---|
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | 6.3125 | |
| cAMP-dependent protein kinase catalytic subunit alpha | Rattus norvegicus (Norway rat) | 0.098 | |
| Sphingosine kinase 2 | Homo sapiens (human) | 1.56 | |
| Sphingosine kinase 1 | Homo sapiens (human) | 3.86 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (21.98) | 18.7374 |
| 1990's | 34 (37.36) | 18.2507 |
| 2000's | 18 (19.78) | 29.6817 |
| 2010's | 15 (16.48) | 24.3611 |
| 2020's | 4 (4.40) | 2.80 |
| Authors | Studies |
|---|---|
| Kanfer, JN; Spielvogel, CH | 1 |
| Broekhuyse, RM; Roelfzema, H; Veerkamp, JH | 1 |
| Bocian, KM; Pagano, RE; Ting, AE; Winiski, AP; Wolf, DE | 1 |
| Anderson, WB; Crilly, KS; Kiss, Z; Rossi, MA | 1 |
| Alesenko, AV; Pushkareva, MIu; Romanenko, EB; Vaniushin, BF | 1 |
| Garcia, MC; Mueller, HW; Rosenthal, MD | 1 |
| Dressler, KA; Kan, CC; Kolesnick, RN | 1 |
| Cornell, RB; Sohal, PS | 1 |
| Delbart, C; Devred, D; Fruchart, JC; Martin-Nizard, F; Nazih, H | 1 |
| Dorn, CC; Rice, WR; Singleton, FM | 1 |
| August, J; Bishop, WR; Pai, JK; Petrin, JM | 1 |
| Insel, PA; Meier, KE; Slivka, SR | 1 |
| Rosing, J; Speijer, H; Tans, G; Zwaal, RF | 1 |
| Bruzik, KS | 1 |
| Cullis, PR; Hope, MJ; Madden, TD | 1 |
| Ahkong, QF; Howell, JI; Lucy, JA; Tampion, W | 1 |
| Alexander, M; Illingworth, DR; Portman, OW | 1 |
| Kanazawa, I; Ueta, N; Yamakawa, T | 1 |
| Anderer, FA; Diringer, H; Koch, MA; Marggraf, WD | 2 |
| Gahmberg, CG; Kääriäinen, L; Kettunen, ML; Laine, R; Renkonen, O | 1 |
| Boggs, JM; Hsia, JC | 1 |
| Bauer, E; Stahl, J; Stoffel, W | 1 |
| Barenholz, Y; Gatt, S | 1 |
| Radin, NS; Ullman, MD | 1 |
| Bartoli, S; Bonora, B; Capitani, S; Manzoli, FA; Muchmore, JH | 1 |
| Frey, CF; Goswami, SK | 1 |
| Melzner, I; Stoffel, W | 1 |
| Kawasaki, Y; Nagai, Y; Uchida, T; Wakayama, N | 1 |
| Barber, KR; Grant, CW; Rigby, AC | 1 |
| Aro, A; Kinnunen, PK; Kõiv, A; Lehtonen, J; Mustonen, P; Rytömaa, M | 1 |
| Lau, B; Macdonald, PM | 1 |
| Alessenko, AV; Romanenko, EB; Vanyushin, BF | 1 |
| Baudet, C; Brachet, P; Galve-Roperh, I; Laviada, ID; Naveilhan, P | 1 |
| Canty, DJ; Zeisel, SH | 1 |
| Breu, J; Eldar, H; Livneh, E; Slack, BE; Wurtman, RJ | 1 |
| Divecha, N; Irvine, RF | 1 |
| Anderson, WB; Kiss, Z; Tomono, M | 1 |
| Anderson, WH; Kiss, Z | 2 |
| Kinnunen, PK; Kõiv, A; Mustonen, P | 1 |
| Kiss, Z | 2 |
| Kinnunen, PK; Kõiv, A; Lehtonen, J; Mustonen, P | 1 |
| Grabska, M; Grzelinska, E; Morita, M; Slomiany, A; Slomiany, BA; Slomiany, BL | 1 |
| Katoh, N | 1 |
| Kinnunen, PK; Lehtonen, JY; Rytömaa, M | 1 |
| Anderson, WH; Crilly, KS; Kiss, Z | 1 |
| Asfaw, B; Cerný, B; Conzelmann, E; Ledvinová, J; Schindler, D; Smíd, F | 1 |
| Holopainen, JM; Kinnunen, PK; Subramanian, M | 1 |
| Malaquias, AT; Oliveira, MM | 1 |
| Matile, S; Tedesco, MM | 1 |
| Ramstedt, B; Slotte, JP | 1 |
| Abe, A; Shayman, JA | 1 |
| Allan, D | 1 |
| Honeyman, T; Ignotz, RA | 1 |
| Allan, D; Shawyer, A; Taylor, A | 1 |
| Colombini, M; Siskind, LJ | 1 |
| Campo, ML; Claro, E; Ramos, B; Salido, GM | 1 |
| Angelova, MI; Hristova, NI; Tsoneva, I | 1 |
| Ikari, S; Matsuda, H; Ochi, S; Oda, M; Sakurai, J | 1 |
| Birukov, KG; Birukova, AA; Bochkov, VN; Bokoch, GM; Garcia, JG; Kawkitinarong, K; Leitinger, N; Leitner, A; Rios, A; Verin, AD | 1 |
| Hojjati, MR; Huan, C; Jiang, XC; Li, Z; Lu, S; Ooi, E; Tang, S; Zhou, H | 1 |
| de Groot, H; Karow, W; Meyer, SG | 1 |
| Cho, W; Hwang, JH; Johnson, KR; Kim, JH; Obeid, LM; Park, ZY; Stahelin, RV | 1 |
| Hyvönen, MT; Niemelä, PS; Vattulainen, I | 1 |
| Chigorno, V; Mikulak, J; Prinetti, A; Sciannamblo, M; Sonnino, S | 1 |
| Kawamura, A; Matsuo, Y; Miura, S; Rye, KA; Saku, K; Uehara, Y | 1 |
| Ito, M; Okino, N | 1 |
| Abe, A; Hiraoka, M; Shayman, JA | 1 |
| Aceves, M; Crespo, MS; Dueñas, AI; Fernández-Pisonero, I; García-Rodríguez, C; Gómez, C; Orduña, A | 1 |
| Bittman, R; Lankalapalli, RS; Sircar, D; Subbaiah, PV | 1 |
| Aureli, M; Casellato, R; Chigorno, V; Ciampa, MG; Loberto, N; Mauri, L; Prinetti, A; Prioni, S; Sonnino, S | 1 |
| Sundh, M; Sutherland, DS; Svedhem, S | 1 |
| Nakahara, H; Sakamoto, S; Shibata, O; Shoyama, Y; Uto, T | 1 |
| Bunte, RM; Chiu, GN; Chng, WJ; Ling, LU; Tan, KB | 1 |
| Carreira, AC; de Almeida, RF; Silva, LC; Zupancic, E | 1 |
| Angelova, MI; Puff, N; Seigneuret, M; Staneva, G; Watanabe, C | 1 |
| Chworos, A; Dabkowska, AP; Höök, F; Jaeger, L; Michanek, A; Nylander, T; Rabe, M; Sparr, E | 1 |
| Anchordoquy, TJ; Betker, JL | 1 |
| Hornemann, T; Landmesser, U; Manz, J; Othman, A; Rentsch, K; Riwanto, M; Rohrer, L; Sutter, I; Velagapudi, S; von Eckardstein, A | 1 |
| Balakrishnan, P; Cho, HJ; Jahn, A; Song, CK | 1 |
| Ogino, T; Yokota, K | 1 |
| Gao, D; Guan, J; Guo, Y; Jiang, Y; Liu, H; Wang, Y; Xie, W; Yang, T | 1 |
| Abe, A; Hiraoka, M; Ohguro, H; Shayman, JA; Tesmer, JJ | 1 |
| Alvares, DS; Ambroggio, EE; Ruggiero Neto, J | 1 |
| Chen, Y; Ding, L; Dong, P; Jiang, M; Shi, H; Wen, S; Yang, J; Yang, Y; Zhu, Y | 1 |
| Eto, Y; Higaki, K; Iwahori, A; Kato, A; Kikuchi, M; Maekawa, M; Mano, N; Narita, A; Noguchi, A; Ogura, J; Okuyama, T; Sato, T; Sato, Y; Takahashi, T | 1 |
| Cai, M; Gao, N; Han, G; Lu, L; Ma, X; Zhao, Z | 1 |
| Boyano, IV; Gómez-Bori, A; Jaras, JH; Lluesa, JH; López-Romero, LC; Marugán, MR; Monzó, JJB; Orient, AS; Perez, PS; Rodríguez-Espinosa, D; Such, RD | 1 |
| Aoki, J; Doi, K; Harada, S; Hashimoto, H; Jubishi, D; Kano, K; Kurano, M; Morita, Y; Moriya, K; Okamoto, K; Okugawa, S; Saigusa, D; Sakai, E; Yatomi, Y | 1 |
3 review(s) available for phosphatidylcholines and sphingosine
| Article | Year |
|---|---|
Enzymes of complex lipid metabolism.
Topics: Acyltransferases; Cardiolipins; Ceramides; Cerebrosides; Colloids; Cytidine; Galactosidases; Glucosidases; Glycerides; Glycolipids; Hexosaminidases; Hydro-Lyases; Hydrolysis; Kinetics; Macromolecular Substances; Neuraminidase; Nucleoside Diphosphate Sugars; Nucleotides; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases; Phospholipids; Sphingolipids; Sphingosine; Sulfatases; Sulfurtransferases | 1973 |
Lecithin and choline in human health and disease.
Topics: Animals; Choline; Choline Deficiency; Humans; Neoplasms; Nutritional Requirements; Phosphatidylcholines; Phospholipids; Signal Transduction; Sphingosine | 1994 |
Phospholipid signaling.
Topics: Animals; Cell Nucleus; Humans; Phosphatidylcholines; Phosphatidylinositols; Phospholipids; Protein Kinase C; Signal Transduction; Sphingolipids; Sphingomyelins; Sphingosine | 1995 |
88 other study(ies) available for phosphatidylcholines and sphingosine
| Article | Year |
|---|---|
Phospholipase C catalyzed formation of sphinogomyelin--14C from lecithin and N-(-14C)-oleoyl-sphingosine.
Topics: Bacillus cereus; Carbon Radioisotopes; Chromatography, Thin Layer; Clostridium perfringens; Egg Yolk; Female; Oleic Acids; Phosphatidylcholines; Phospholipases; Plants; Species Specificity; Sphingomyelins; Sphingosine | 1975 |
Lipids in tissues of the eye XI. Synthesis of sphingomyelin in the calf lens.
Topics: Animals; Cattle; Ceramides; Coenzyme A; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Epithelium; Lens, Crystalline; Liver; Microsomes; Phosphatidylcholines; Phosphorylcholine; Rats; Sphingomyelins; Sphingosine; Stearates; Transferases | 1976 |
Determination of the transbilayer distribution of fluorescent lipid analogues by nonradiative fluorescence resonance energy transfer.
Topics: 4-Chloro-7-nitrobenzofurazan; Energy Transfer; Fluorescent Dyes; Lipid Bilayers; Liposomes; Lysophospholipids; Models, Molecular; Molecular Structure; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorylcholine; Rhodamines; Spectrometry, Fluorescence; Sphingosine | 1992 |
Selective inhibition by 4-hydroxynonenal of sphingosine-stimulated phospholipase D in NIH 3T3 cells.
Topics: 3T3 Cells; Aldehydes; Animals; Enzyme Activation; Hydrolysis; Mice; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Sphingosine; Tetradecanoylphorbol Acetate | 1992 |
[Effect of sphingomyelin and its enzymatic hydrolysis products on heterologous methylation of calf thymus DNA by cytosine-DNA-methyltransferase EcoRII].
Topics: Animals; Cattle; Choline; Deoxyribonucleases, Type II Site-Specific; DNA; Hydrolysis; Methylation; Phosphatidylcholines; Sphingomyelins; Sphingosine; Thymus Gland | 1991 |
C20 polyunsaturated fatty acids and phorbol myristate acetate enhance agonist-stimulated synthesis of 1-radyl-2-acetyl-sn-glycero-3-phosphocholine in vascular endothelial cells.
Topics: Acetates; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cattle; Endothelium, Vascular; Fatty Acids, Unsaturated; Kinetics; Phosphatidylcholines; Sphingosine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tritium | 1991 |
Sphingomyelin synthesis is involved in adherence during macrophage differentiation of HL-60 cells.
Topics: Cell Adhesion; Cell Line; Ceramides; Macrophages; Phosphatidylcholines; Phospholipases; Phosphorylcholine; Sphingomyelins; Sphingosine; Tetradecanoylphorbol Acetate | 1991 |
Sphingosine inhibits the activity of rat liver CTP:phosphocholine cytidylyltransferase.
Topics: Animals; Choline-Phosphate Cytidylyltransferase; Kinetics; Liposomes; Liver; Male; Nucleotidyltransferases; Oleic Acid; Oleic Acids; Phosphatidylcholines; Rats; Rats, Inbred Strains; Sphingolipids; Sphingosine; Structure-Activity Relationship | 1990 |
Phosphatidylcholine breakdown in HDL3 stimulated platelets.
Topics: Blood Platelets; Diacylglycerol Kinase; Diglycerides; Humans; In Vitro Techniques; Lipoproteins, HDL; Lipoproteins, HDL3; Phosphatidic Acids; Phosphatidylcholines; Phosphotransferases; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1990 |
P2-purinoceptor regulation of surfactant phosphatidylcholine secretion. Relative roles of calcium and protein kinase C.
Topics: Adenosine Triphosphate; Animals; Calcium; Diglycerides; Guanosine Triphosphate; Inositol Phosphates; Male; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sphingosine; Terbutaline | 1990 |
Regulation of sn-1,2-diacylglycerol second-messenger formation in thrombin-stimulated human platelets. Potentiation by protein kinase C inhibitors.
Topics: Alkaloids; Blood Platelets; Carbazoles; Diglycerides; Drug Synergism; Enzyme Activation; Feedback; Glycerides; Humans; Indole Alkaloids; Neomycin; Phosphatidic Acids; Phosphatidylcholines; Phosphorylation; Propranolol; Protein Kinase C; Second Messenger Systems; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Alpha 1-adrenergic receptors promote phosphatidylcholine hydrolysis in MDCK-D1 cells. A mechanism for rapid activation of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Cell Membrane; Cytosol; Diglycerides; Dogs; Enzyme Activation; Epinephrine; Hydrolysis; Isoquinolines; Kidney; Kinetics; Neomycin; Phosphatidylcholines; Phosphorylcholine; Piperazines; Protein Kinase C; Receptors, Adrenergic, alpha; Sphingosine | 1988 |
Calcium-independent activation of prothrombin on membranes with positively charged lipids.
Topics: 1-Carboxyglutamic Acid; Amines; Animals; Calcium; Cattle; Cetrimonium; Cetrimonium Compounds; Electrochemistry; Factor V; Factor X; Factor Xa; Liposomes; Membrane Lipids; Phosphatidylcholines; Prothrombin; Serine Endopeptidases; Sphingosine | 1988 |
Conformation of the polar headgroup of sphingomyelin and its analogues.
Topics: Choline; Magnetic Resonance Spectroscopy; Molecular Conformation; Phosphatidylcholines; Sphingomyelins; Sphingosine; Stereoisomerism | 1988 |
Modelling the biological membrane.
Topics: Liposomes; Membrane Lipids; Membrane Potentials; Membrane Proteins; Models, Biological; Permeability; Phosphatidylcholines; Sphingosine | 1987 |
The fusion of hen erythrocytes by lipid-soluble and surface-active immunological adjuvants.
Topics: Adjuvants, Immunologic; Alkanes; Animals; Binding Sites; Cell Fusion; Chickens; Chromatography; Chromatography, Thin Layer; Detergents; Egg Yolk; Erythrocytes; Female; Freund's Adjuvant; Microscopy, Electron; Microscopy, Phase-Contrast; Phosphatidylcholines; Silicon Dioxide; Solubility; Sphingosine; Staining and Labeling; Surface-Active Agents | 1974 |
Lysolecithin and sphingosinephosphoryl-choline in the metabolism of brain phospholipids of the rhesus monkey (Macaca mulatta): effects of development.
Topics: Aging; Animals; Animals, Newborn; Brain; Carbon Isotopes; Cerebral Cortex; Choline; Chromatography, Thin Layer; Coenzyme A; Cytosine Nucleotides; Fetus; Haplorhini; Lysophosphatidylcholines; Macaca; Organophosphorus Compounds; Palmitic Acids; Phosphatidylcholines; Phospholipases; Phospholipids; Pons; Sphingomyelins; Sphingosine | 1973 |
The incorporation of labelled acetate into cerebroside and other lipids of the developing mouse brain.
Topics: Acetates; Animals; Brain; Carbon Isotopes; Cardiolipins; Cerebrosides; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids, Nonesterified; Female; Glycolipids; Lipids; Male; Mice; Mice, Inbred Strains; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Sphingomyelins; Sphingosine; Sulfoglycosphingolipids; Triglycerides | 1972 |
Evidence for a new biosynthetic pathway of sphingomyelin in SV 40 transformed mouse cells.
Topics: Acetates; Animals; Autoradiography; Cell Transformation, Neoplastic; Choline; Chromatography, Thin Layer; Fibroblasts; Isotope Labeling; Kinetics; Mice; Phosphates; Phosphatidylcholines; Phosphorus Isotopes; Simian virus 40; Sphingomyelins; Sphingosine; Time Factors; Tritium | 1972 |
Fatty chains of different lipid classes of Semliki forest virus and host cell membranes.
Topics: Aldehydes; Animals; Cell Line; Cell Membrane; Chromatography, Gas; Chromatography, Thin Layer; Clone Cells; Cricetinae; Endoplasmic Reticulum; Fatty Acids; Gangliosides; Kidney; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Semliki forest virus; Sphingolipids; Sphingomyelins; Sphingosine | 1972 |
Structural characteristics of hydrated glycerol-and sphingo-lipids. A spin label study.
Topics: Animals; Brain Chemistry; Cardiolipins; Cattle; Ceramides; Cerebrosides; Cholesterol; Electron Spin Resonance Spectroscopy; Fatty Acids; Gangliosides; Glycerides; Glycerol; Lipids; Liposomes; Liver; Myocardium; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Sphingolipids; Sphingomyelins; Sphingosine; Spin Labels; Swine | 1973 |
The metabolism of sphingosine bases in Tetrahymena pyriformis. Sphingosine kinase and sphingosine-1-phosphate lyase.
Topics: Alcohol Oxidoreductases; Aldehyde-Lyases; Alkenes; Animals; Carbon Radioisotopes; Chromatography, Gas; Chromatography, Ion Exchange; Coenzymes; Ethers; Fatty Alcohols; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Oxidoreductases; Oxygen Isotopes; Palmitic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphotransferases; Radioisotopes; Sphingosine; Tetrahymena pyriformis; Tritium | 1974 |
[Biosynthesis of sphingomyelin].
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Choline; Cytosine Nucleotides; Glycerol; Mice; Phosphatidylcholines; Phosphorus Isotopes; Simian virus 40; Sphingomyelins; Sphingosine | 1972 |
The enzymatic formation of sphingomyelin from ceramide and lecithin in mouse liver.
Topics: Acetates; Animals; Carbon Radioisotopes; Ceramides; Choline; Cytosine Nucleotides; Fatty Acids; Freeze Drying; Glycerides; Liver; Male; Manganese; Mice; Microsomes, Liver; Organ Specificity; Organophosphorus Compounds; Palmitic Acids; Phosphatidylcholines; Phosphorus Radioisotopes; Sphingomyelins; Sphingosine; Structure-Activity Relationship; Transferases | 1974 |
Lipid--DNA interactions. II. Phospholipids, cholesterol, glycerophosphorylcholine, spingosine and fatty acids.
Topics: Animals; Binding Sites; Cattle; Cholesterol; DNA; Drug Stability; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Glycerylphosphorylcholine; Hot Temperature; Kinetics; Mathematics; Nucleic Acid Denaturation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Sodium Chloride; Spectrophotometry, Ultraviolet; Sphingosine; Thiocyanates; Thymus Gland | 1974 |
Spray detection of phospholipids on thin-layer chromatograms.
Topics: Chromatography, Thin Layer; Copper; Evaluation Studies as Topic; Indicators and Reagents; Methods; Microchemistry; Molybdenum; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Sphingomyelins; Sphingosine; Sulfuric Acids | 1971 |
Studies in vitro on the biosynthesis of ceramide and sphingomyelin. A reevaluation of proposed pathways.
Topics: Acyl Coenzyme A; Animals; Ceramides; Cytidine Diphosphate Choline; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Microsomes, Liver; Phosphatidylcholines; Phosphotransferases; Rats; Sphingomyelins; Sphingosine; Stereoisomerism; Transferases (Other Substituted Phosphate Groups) | 1980 |
Fluorospectroscopic studies of various ganglioside and ganglioside--lecithin dispersions. Steady-state and time-resolved fluorescence measurements with 1,6-diphenyl-1,3,5-hexatriene.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Cattle; Chemical Phenomena; Chemistry; Diphenylhexatriene; Fatty Acids; Gangliosides; Kinetics; Mathematics; Molecular Conformation; Phosphatidylcholines; Polyenes; Spectrometry, Fluorescence; Sphingosine; Temperature | 1981 |
2H-NMR study of two probe-labelled glycosphingolipid-derived signalling modulators in bilayer membranes.
Topics: Cell Membrane; Ceramides; Cholesterol; Deuterium; Glycosphingolipids; Hydrogen-Ion Concentration; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Probes; Molecular Structure; Phosphatidylcholines; Sphingosine | 1995 |
Sphingosine-mediated membrane association of DNA and its reversal by phosphatidic acid.
Topics: Bisbenzimidazole; Calorimetry, Differential Scanning; DNA; Doxorubicin; Liposomes; Membrane Fusion; Microscopy, Fluorescence; Phosphatidic Acids; Phosphatidylcholines; Spectrometry, Fluorescence; Sphingosine | 1993 |
Determination of the pKa of membrane-bound N,N-dimethylsphingosine using deuterium NMR spectroscopy.
Topics: Deuterium; Hydrogen-Ion Concentration; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Protein Kinase C; Sphingosine | 1995 |
Effect of sphingomyelin and antioxidants on the in vitro and in vivo DNA methylation.
Topics: Animals; Antioxidants; Base Composition; Butylated Hydroxytoluene; Cattle; Cell Nucleus; DNA; Methionine; Methylation; Nucleotides; Octoxynol; Phosphatidylcholines; Phospholipids; Phosphorylcholine; Rats; Sphingomyelins; Sphingosine; Thymus Gland; Tritium | 1995 |
Phosphatidylcholine-phospholipase C mediates the induction of nerve growth factor in cultured glial cells.
Topics: Animals; Blotting, Northern; Brain; Cells, Cultured; Enzyme Activation; Hydrolysis; Nerve Growth Factors; Neuroglia; Phosphatidylcholines; Protein Kinase C; Rats; RNA, Messenger; Sphingosine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1995 |
Phorbol ester stimulates choline uptake in Swiss 3T3 fibroblasts following introduction of the gene encoding protein kinase C alpha.
Topics: 3T3 Cells; Animals; Biological Transport; Blotting, Western; Carbon Radioisotopes; Choline; Dose-Response Relationship, Drug; Isoenzymes; Isotope Labeling; Mice; Phosphatidylcholines; Phosphorylcholine; Protein Kinase C; Protein Kinase C-alpha; Recombinant Proteins; Sphingosine; Tetradecanoylphorbol Acetate | 1995 |
Phorbol ester selectively stimulates the phospholipase D-mediated hydrolysis of phosphatidylethanolamine in multidrug-resistant MCF-7 human breast carcinoma cells.
Topics: Breast Neoplasms; Drug Resistance, Multiple; Glycerophospholipids; Glycerylphosphorylcholine; Humans; Hydrogen Peroxide; Hydrolysis; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Selective down-regulation of protein kinase c-epsilon by carcinogens does not prevent stimulation of phospholipase D by phorbol ester and platelet-derived growth factor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Benzo(a)pyrene; Carcinogens; Cell Line; Isoenzymes; Mice; Mice, Inbred C3H; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Platelet-Derived Growth Factor; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Influence of sphingosine on the thermal phase behaviour of neutral and acidic phospholipid liposomes.
Topics: Calorimetry, Differential Scanning; Liposomes; Phosphatidylcholines; Phosphatidylserines; Sphingosine; Structure-Activity Relationship | 1993 |
The zinc chelator 1,10-phenanthroline enhances the stimulatory effects of protein kinase C activators and staurosporine, but not sphingosine and H2O2, on phospholipase D activity in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Alkaloids; Animals; Chelating Agents; Enzyme Activation; Hydrogen Peroxide; Hydrolysis; Mice; Phenanthrolines; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Zinc | 1994 |
Sphingosine-like stimulatory effects of propranolol on phospholipase D activity in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Carbon Radioisotopes; Diglycerides; Drug Synergism; Mice; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Propranolol; Sphingosine; Tetradecanoylphorbol Acetate | 1994 |
Hydrogen peroxide regulates phospholipase D-mediated hydrolysis of phosphatidylethanolamine and phosphatidylcholine by different mechanisms in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Alkaloids; Animals; Fibroblasts; Hydrogen Peroxide; Hydrolysis; Kinetics; Mice; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Sphingosine; Staurosporine; Substrate Specificity; Tetradecanoylphorbol Acetate | 1994 |
Effects of sphingosine on peripheral membrane interactions: comparison of adriamycin, cytochrome c, and phospholipase A2.
Topics: Calcium; Cell Membrane; Cytochrome c Group; Doxorubicin; Electrochemistry; Energy Transfer; Hydrolysis; Liposomes; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylglycerols; Phospholipases A; Phospholipases A2; Spectrometry, Fluorescence; Sphingosine | 1993 |
Intracellular transport, organelle biogenesis and establishment of Golgi identity: impact of brefeldin A on the activity of lipid synthesizing enzymes.
Topics: Acyltransferases; Autoradiography; Brefeldin A; Cell Fractionation; Ceramides; Choline-Phosphate Cytidylyltransferase; Cyclopentanes; Diacylglycerol Cholinephosphotransferase; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Glycerophosphates; Glycosylation; Golgi Apparatus; Membrane Lipids; Nucleotidyltransferases; Phosphatidylcholines; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine | 1993 |
Inhibition by phospholipids, lysophospholipids and gangliosides of melittin-induced phosphorylation in bovine mammary gland.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Female; Gangliosides; Lysophospholipids; Mammary Glands, Animal; Melitten; Molecular Weight; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Phosphorylation; Protein Kinase C; Sphingosine; Structure-Activity Relationship; Substrate Specificity | 1995 |
Characteristics of the binding of tacrine to acidic phospholipids.
Topics: Cholinesterase Inhibitors; Dimyristoylphosphatidylcholine; Kinetics; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphatidylinositols; Phospholipids; Sphingosine; Structure-Activity Relationship; Tacrine | 1996 |
Extracellular sphingosine 1-phosphate stimulates formation of ethanolamine from phosphatidylethanolamine: modulation of sphingosine 1-phosphate-induced mitogenesis by ethanolamine.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; DNA; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Ethanolamine; Flavonoids; Gene Expression Regulation, Enzymologic; Hydrolysis; Insulin; Lysophospholipids; Mice; Mitogens; Mitosis; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Sphingosine; Tetradecanoylphorbol Acetate | 1997 |
Degradation of blood group A glycolipid A-6-2 by normal and mutant human skin fibroblasts.
Topics: ABO Blood-Group System; alpha-N-Acetylgalactosaminidase; Apolipoproteins E; Carbohydrate Conformation; Carbohydrate Sequence; Cells, Cultured; Fibroblasts; Fucosidosis; Glycosphingolipids; Hexosaminidases; Humans; Liposomes; Lysosomal Storage Diseases; Molecular Sequence Data; Phosphatidylcholines; Skin; Sphingomyelins; Sphingosine; Tritium | 1998 |
Sphingomyelinase induces lipid microdomain formation in a fluid phosphatidylcholine/sphingomyelin membrane.
Topics: Animals; Cattle; Ceramides; Hydrolysis; Lipid Bilayers; Liposomes; Phosphatidylcholines; Spectrometry, Fluorescence; Sphingomyelin Phosphodiesterase; Sphingomyelins; Sphingosine; Thermodynamics | 1998 |
Phospholipid signalling pathways in Trypanosoma cruzi growth control.
Topics: Adenylate Cyclase Toxin; Animals; Benzylamines; Carbazoles; Cell Division; Culture Media; Cyclic AMP; Dose-Response Relationship, Drug; Estrenes; Indoles; Lysophospholipids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Protein Kinases; Pyrroles; Pyrrolidinones; Signal Transduction; Sphingosine; Staurosporine; Sulfonamides; Trypanosoma cruzi; Type C Phospholipases; Virulence Factors, Bordetella | 1999 |
Spectroscopic detection of endovesiculation by large unilamellar phosphatidylcholine vesicles: effects of chlorpromazine, dibucaine, and safingol.
Topics: Arylsulfonates; Chlorpromazine; Dibucaine; Dose-Response Relationship, Drug; Endocytosis; Fluorescent Dyes; Liposomes; Phosphatidylcholines; Pyridinium Compounds; Spectrum Analysis; Sphingosine | 1999 |
Comparison of the biophysical properties of racemic and d-erythro-N-acyl sphingomyelins.
Topics: Biophysics; Indicators and Reagents; Liposomes; Microscopy, Fluorescence; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Sphingomyelin Phosphodiesterase; Sphingomyelins; Sphingosine; Stereoisomerism; Structure-Activity Relationship | 1999 |
1-O-acylceramide synthase.
Topics: Acylation; Acyltransferases; Animals; Arachidonic Acid; Brain; Cattle; Cells, Cultured; Ceramides; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A2; Sphingolipids; Sphingosine | 2000 |
Lipid metabolic changes caused by short-chain ceramides and the connection with apoptosis.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Apoptosis; Boron Compounds; Cell Line; Ceramides; Cholesterol; Cricetinae; Fibroblasts; Kidney; Lipid Metabolism; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Sphingolipids; Sphingomyelins; Sphingosine | 2000 |
TGF-beta signaling in A549 lung carcinoma cells: lipid second messengers.
Topics: Acetophenones; Arachidonic Acid; Bridged-Ring Compounds; Calcium; Chelating Agents; Chromatography, Thin Layer; Diglycerides; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix; Humans; Hydrolysis; Lipids; Lung Neoplasms; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Plasmids; Protein Isoforms; Second Messenger Systems; Sphingosine; Thiocarbamates; Thiones; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured; Type C Phospholipases | 2000 |
Mechanisms by which short-chain ceramides cause apoptosis.
Topics: Acetates; Animals; Anticholesteremic Agents; Apoptosis; Cell Line; Ceramides; Cricetinae; Dose-Response Relationship, Drug; Fibroblasts; Kidney; Phosphatidylcholines; Sphingomyelins; Sphingosine | 1999 |
The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis.
Topics: Apoptosis; Ceramides; Cholesterol; Electric Conductivity; Electrochemistry; Ion Channels; Liposomes; Models, Biological; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Phospholipids; Sphingosine; Structure-Activity Relationship | 2000 |
Inhibition of phosphatidylcholine synthesis precedes apoptosis induced by C2-ceramide: protection by exogenous phosphatidylcholine.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Membrane; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Neurons; Neuroprotective Agents; Phosphatidylcholines; Rats; Rats, Wistar; Signal Transduction; Sphingosine | 2000 |
An experimental approach for direct observation of the interaction of polyanions with sphingosine-containing giant vesicles.
Topics: Acrylic Resins; Adenosine Triphosphate; Dextran Sulfate; DNA; Heparin; Kinetics; Liposomes; Microscopy, Fluorescence; Phosphatidylcholines; Polyelectrolytes; Polymers; Sphingosine | 2002 |
Clostridium perfringens alpha-toxin activates the sphingomyelin metabolism system in sheep erythrocytes.
Topics: 4-Aminobenzoic Acid; ADP Ribose Transferases; Amidohydrolases; Animals; Bacterial Toxins; Botulinum Toxins; Calcium-Binding Proteins; Ceramidases; Chromatography, Thin Layer; Diglycerides; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Erythrocytes; Ethanolamines; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hemolysis; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Oleic Acids; para-Aminobenzoates; Pertussis Toxin; Phosphatidylcholines; Phosphorylcholine; Phosphotransferases (Alcohol Group Acceptor); Rabbits; Sheep; Sphingomyelins; Sphingosine; Time Factors; Toxins, Biological; Type C Phospholipases | 2004 |
Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac.
Topics: Butylated Hydroxytoluene; cdc42 GTP-Binding Protein; Cytoskeleton; Dimyristoylphosphatidylcholine; DNA, Complementary; Electric Impedance; Endothelial Cells; Endothelium, Vascular; Humans; Isoprostanes; Lysophospholipids; Oxidation-Reduction; Phosphatidylcholines; Pulmonary Artery; rac GTP-Binding Proteins; rho GTP-Binding Proteins; RNA, Small Interfering; Spectrometry, Mass, Electrospray Ionization; Sphingosine; Structure-Activity Relationship; Thrombin; Transfection | 2004 |
Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice.
Topics: Acyltransferases; Animal Feed; Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Ceramides; Cholesterol; Fatty Acids, Monounsaturated; Immunosuppressive Agents; Lipid Metabolism; Lipids; Lipoproteins; Lysophospholipids; Mass Spectrometry; Mice; Mice, Knockout; Phosphatidylcholines; Serine C-Palmitoyltransferase; Signal Transduction; Sphingolipids; Sphingosine; Time Factors; Triglycerides | 2005 |
2n-fatty acids from phosphatidylcholine label sphingolipids--a novel role of phospholipase A2?
Topics: Animals; Carbon Isotopes; Ceramides; Chromatography, Gel; Fatty Acids; Hydrolysis; Isotope Labeling; Mass Spectrometry; Mice; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Sphingolipids; Sphingomyelin Phosphodiesterase; Sphingomyelins; Sphingosine | 2005 |
The mechanism of membrane targeting of human sphingosine kinase 1.
Topics: Amino Acid Sequence; Asparagine; Cell Line; Cell Membrane; DNA Mutational Analysis; Green Fluorescent Proteins; Humans; Kinetics; Lipids; Lysophospholipids; Mass Spectrometry; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Mutation; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Pressure; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Sphingosine; Surface Plasmon Resonance; Threonine; Time Factors; Transfection | 2005 |
Influence of chain length and unsaturation on sphingomyelin bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biophysics; Carbon; Computer Simulation; Diffusion; Electrons; Hydrogen Bonding; Lipid Bilayers; Membrane Fluidity; Models, Chemical; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Phospholipids; Sphingomyelins; Sphingosine; Time Factors | 2006 |
Efflux of sphingolipids metabolically labeled with [1-3H]sphingosine, L-[3- 3H]serine and [9,10- 3H]palmitic acid from normal cells in culture.
Topics: Animals; Carbohydrate Sequence; Cells, Cultured; Cerebellum; Culture Media; Fibroblasts; G(M3) Ganglioside; Humans; Molecular Sequence Data; Palmitic Acid; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Reference Values; Serine; Sphingolipids; Sphingomyelins; Sphingosine; Tritium | 2006 |
Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation.
Topics: Animals; Atherosclerosis; Cell Division; Cells, Cultured; CHO Cells; Cholesterol; Coronary Vessels; Cricetinae; Cricetulus; Endothelial Cells; Enzyme Inhibitors; Humans; In Vitro Techniques; Lipoproteins, HDL; Lysophospholipids; Macrophages; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oligonucleotides, Antisense; Phosphatidylcholines; Proto-Oncogene Proteins c-akt; ras Proteins; Sphingosine | 2007 |
Ceramidase enhances phospholipase C-induced hemolysis by Pseudomonas aeruginosa.
Topics: Amidohydrolases; Animals; Ceramidases; Ceramides; Erythrocytes; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Hemolysis; Humans; Lipids; Neutral Ceramidase; Phosphatidylcholines; Pseudomonas aeruginosa; Sheep; Sphingomyelins; Sphingosine; Type C Phospholipases | 2007 |
The acylation of lipophilic alcohols by lysosomal phospholipase A2.
Topics: Acyltransferases; Alcohols; Animals; Cell Line; Dogs; Endosomes; Ethanol; Lysosomes; Models, Biological; Models, Chemical; Monoglycerides; Phosphatidylcholines; Phospholipases A2; Sphingosine; Time Factors | 2007 |
Selective attenuation of Toll-like receptor 2 signalling may explain the atheroprotective effect of sphingosine 1-phosphate.
Topics: Atherosclerosis; Cell Line; Chemokines; Enzyme Inhibitors; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lysophospholipids; NF-kappa B; Phagocytes; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; ras Proteins; Receptors, Lysosphingolipid; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Time Factors; Toll-Like Receptor 2; Transcription, Genetic; Transfection | 2008 |
Effect of double bond geometry in sphingosine base on the antioxidant function of sphingomyelin.
Topics: Antioxidants; Ascorbic Acid; Cations, Divalent; Cholesterol; Copper; Ferrous Compounds; Lipid Peroxidation; Oxidation-Reduction; Phosphatidylcholines; Sphingomyelins; Sphingosine; Stereoisomerism | 2009 |
Photoactivable sphingosine as a tool to study membrane microenvironments in cultured cells.
Topics: Biotinylation; Cell Membrane; Cell Proliferation; Cell Survival; Cells, Cultured; Child; Cross-Linking Reagents; Humans; Immunoprecipitation; Lipids; Membrane Microdomains; Membrane Proteins; Niemann-Pick Disease, Type A; Phosphatidylcholines; Photochemical Processes; Skin; Sphingomyelins; Sphingosine; Streptavidin; Time Factors | 2010 |
Influence of phase separating lipids on supported lipid bilayer formation at SiO2 surfaces.
Topics: Cholesterol; Lipid Bilayers; Microscopy, Fluorescence; Phosphatidylcholines; Phosphorylcholine; Silicon Dioxide; Sphingosine; Surface Properties; Temperature | 2010 |
Investigation of interfacial behavior of glycyrrhizin with a lipid raft model via a Langmuir monolayer study.
Topics: Cholesterol; Glycyrrhizic Acid; Membrane Microdomains; Microscopy, Fluorescence; Phosphatidylcholines; Phosphorylcholine; Sphingosine | 2013 |
Liposomal codelivery of a synergistic combination of bioactive lipids in the treatment of acute myeloid leukemia.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Ceramides; Cholesterol; Chromatography, Liquid; Drug Delivery Systems; Female; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Lipids; Liposomes; Mice; Mice, Inbred BALB C; Mice, SCID; Phosphatidylcholines; Sphingosine; Tandem Mass Spectrometry; U937 Cells; Xenograft Model Antitumor Assays | 2014 |
Biophysical implications of sphingosine accumulation in membrane properties at neutral and acidic pH.
Topics: Cholesterol; Fluorescence Polarization; Hydrogen-Ion Concentration; Liposomes; Membrane Fluidity; Membrane Microdomains; Phase Transition; Phosphatidylcholines; Sphingomyelins; Sphingosine; Static Electricity | 2014 |
Antagonism and synergy of single chain sphingolipids sphingosine and sphingosine-1-phosphate toward lipid bilayer properties. Consequences for their role as cell fate regulators.
Topics: Lipid Bilayers; Lysophospholipids; Phosphatidylcholines; Sphingosine; Unilamellar Liposomes | 2014 |
Assembly of RNA nanostructures on supported lipid bilayers.
Topics: Cations; Fluorescence Recovery After Photobleaching; Lipid Bilayers; Microscopy, Fluorescence; Nanostructures; Phosphatidylcholines; Quartz Crystal Microbalance Techniques; RNA; Sphingosine | 2015 |
Relating toxicity to transfection: using sphingosine to maintain prolonged expression in vitro.
Topics: Cations; Cell Survival; DNA; Fatty Acids, Monounsaturated; Flow Cytometry; Gene Expression Regulation; Gene Transfer Techniques; Humans; Lipids; Liposomes; MCF-7 Cells; Particle Size; Phosphatidylcholines; Phosphatidylethanolamines; Plasmids; Quaternary Ammonium Compounds; Sphingosine; Time Factors; Transfection | 2015 |
Plasmalogens of high-density lipoproteins (HDL) are associated with coronary artery disease and anti-apoptotic activity of HDL.
Topics: Acute Coronary Syndrome; Adult; Aged; Apolipoprotein A-I; Apoptosis; Case-Control Studies; Chromatography, Liquid; Coronary Artery Disease; Discriminant Analysis; Endothelial Cells; Female; Humans; Least-Squares Analysis; Lipids; Lipoproteins, HDL; Lysophosphatidylcholines; Lysophospholipids; Male; Mass Spectrometry; Middle Aged; Phosphatidylcholines; Plasmalogens; Sphingomyelins; Sphingosine | 2015 |
Ceramide and N,N,N-Trimethylphytosphingosine-Iodide (TMP-I)-Based Lipid Nanoparticles for Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Ceramides; Chemistry, Pharmaceutical; Delayed-Action Preparations; Docetaxel; Excipients; Male; Mice; Nanoparticles; Neoplasms; Particle Size; Phosphatidylcholines; Poloxalene; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Sphingosine; Taxoids | 2016 |
Phase separation in lipid bilayer membranes induced by intermixing at a boundary of two phases with different components.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Glycerylphosphorylcholine; Lipid Bilayers; Microscopy, Fluorescence; Models, Molecular; Phosphatidylcholines; Phosphorylcholine; Sphingosine | 2015 |
Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line.
Topics: Antineoplastic Agents; Biological Products; Cell Survival; Chromatography, High Pressure Liquid; Colon; Colonic Neoplasms; HCT116 Cells; Humans; Lactones; Lysophosphatidylcholines; Lysophospholipids; Metabolic Networks and Pathways; Metabolomics; Phosphatidylcholines; Phosphorylcholine; Sphingosine; Tandem Mass Spectrometry | 2016 |
Preferential hydrolysis of truncated oxidized glycerophospholipids by lysosomal phospholipase A2.
Topics: Acylation; Amiodarone; Animals; CHO Cells; Cricetulus; Fatty Acids; Glycerophospholipids; Hydrogen-Ion Concentration; Hydrolysis; Liposomes; Lysosomes; Oxidation-Reduction; Phosphatidylcholines; Phospholipases A2; Sphingosine | 2017 |
Phosphatidylserine lipids and membrane order precisely regulate the activity of Polybia-MP1 peptide.
Topics: Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Biological Transport; Cell Line, Tumor; Cell Membrane; Cholesterol; Fluorescent Dyes; Humans; Kinetics; Membrane Lipids; Organ Specificity; Phosphatidylcholines; Phosphatidylserines; Porosity; Sphingosine; Unilamellar Liposomes; Wasp Venoms; Wasps | 2017 |
Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE
Topics: Animals; Atherosclerosis; Biomarkers; Chromatography, High Pressure Liquid; Diet, High-Fat; Discriminant Analysis; Disease Models, Animal; Disease Progression; Dyslipidemias; Genetic Predisposition to Disease; Lipids; Male; Mass Spectrometry; Metabolomics; Mice, Inbred C57BL; Mice, Knockout, ApoE; Pattern Recognition, Automated; Phenotype; Phosphatidylcholines; Plaque, Atherosclerotic; Sphingomyelins; Sphingosine | 2017 |
Development of a Diagnostic Screening Strategy for Niemann-Pick Diseases Based on Simultaneous Liquid Chromatography-Tandem Mass Spectrometry Analyses of N-Palmitoyl-O-phosphocholine-serine and Sphingosylphosphorylcholine.
Topics: Chromatography, Liquid; Humans; Niemann-Pick Diseases; Phosphatidylcholines; Phosphorylcholine; Sphingosine; Tandem Mass Spectrometry | 2020 |
Lipidomics profiling of skin surface lipids in senile pruritus.
Topics: Aged; Ceramides; Chromatography, Liquid; Diglycerides; Female; Humans; Lipidomics; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Pruritus; Skin; Sphingosine; Tandem Mass Spectrometry | 2020 |
Lipidic profiles of patients starting peritoneal dialysis suggest an increased cardiovascular risk beyond classical dyslipidemia biomarkers.
Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Ceramides; Cholesterol Esters; Dialysis Solutions; Dyslipidemias; Fatty Acids, Nonesterified; Glucose; Heart Disease Risk Factors; Humans; Kidney Failure, Chronic; Lysophosphatidylcholines; Middle Aged; Peritoneal Dialysis; Phosphatidylcholines; Phosphatidylethanolamines; Risk Factors; Sphingomyelins; Sphingosine | 2022 |
Dynamic modulations of urinary sphingolipid and glycerophospholipid levels in COVID-19 and correlations with COVID-19-associated kidney injuries.
Topics: Ceramides; COVID-19; Cross-Sectional Studies; Glycerophospholipids; Humans; Kidney; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphatidylserines; Retrospective Studies; SARS-CoV-2; Sphingolipids; Sphingosine | 2022 |