phosphatidylcholines has been researched along with simvastatin in 9 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (simvastatin) | Trials (simvastatin) | Recent Studies (post-2010) (simvastatin) |
|---|---|---|---|---|---|
| 32,204 | 443 | 5,593 | 8,442 | 1,730 | 3,630 |
| Protein | Taxonomy | phosphatidylcholines (IC50) | simvastatin (IC50) |
|---|---|---|---|
| photoreceptor-specific nuclear receptor | Homo sapiens (human) | 1.164 | |
| transactivating tegument protein VP16 [Human herpesvirus 1] | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | 4.426 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.7843 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 9.5 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 0.0034 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.0034 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0111 | |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | 0.049 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 6.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Escousse, A; Goudonnet, H; Mercenne, F; Mounie, J; Truchot, RC | 1 |
| Akhmedzhanov, NM; Oganov, RG; Olfer'ev, AM; Ozerova, IN; Paramonova, IV; Pavlova, LI; Perova, NV | 1 |
| Akhmedzhanov, NM; Aleksandrova, MA; Olfer'ev, AM; Ozerova, IN; Paramonova, IV; Perova, NV | 1 |
| Akhmedzhanov, NM; Ozerova, IN; Paramonova, IV; Perova, NV | 1 |
| D'Alexandri, FL; Fiehn, O; Grapov, D; Haeggström, JZ; Hyötyläinen, T; Newman, JW; Orešič, M; Pedersen, TL; Pernow, J; Settergren, M; Snowden, SG; Wheelock, CE | 1 |
| Achim, M; Muntean, D; Porfire, A; Tomuta, I; Vlase, L | 1 |
| An, W; Jiang, C; Li, Z; Liu, J; Qi, W; Tang, B; Tian, L; Wang, X; Wu, Q; Wu, W; Xie, K; Yang, J; Zhang, Y | 1 |
| Aganov, A; Galiullina, LF; Huster, D; Klochkov, V; Scheidt, HA | 1 |
| Teo, RD; Tieleman, DP | 1 |
3 trial(s) available for phosphatidylcholines and simvastatin
| Article | Year |
|---|---|
Effects of simvastatin on the phospholipid composition of high-density lipoproteins in patients with hypercholesterolemia.
Topics: Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Cardiolipins; Cholesterol; Cholesterol, HDL; Humans; Hypercholesterolemia; Lysophosphatidylcholines; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Simvastatin; Sphingomyelins; Triglycerides | 2001 |
Simvastatin and preparation of polyunsaturated phospholipids produce similar changes in the phospholipid composition of high-density lipoproteins during hypercholesterolemia.
Topics: Adult; Aged; Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Lipoproteins, HDL; Middle Aged; Phosphatidylcholines; Phospholipids; Simvastatin | 2005 |
High-dose simvastatin exhibits enhanced lipid-lowering effects relative to simvastatin/ezetimibe combination therapy.
Topics: Aged; Analysis of Variance; Anticholesteremic Agents; Azetidines; Ceramides; Cholesterol; Cholesterol, LDL; Discriminant Analysis; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Ezetimibe, Simvastatin Drug Combination; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Phosphatidylcholines; Simvastatin; Sphingomyelins; Treatment Outcome; Triglycerides | 2014 |
6 other study(ies) available for phosphatidylcholines and simvastatin
| Article | Year |
|---|---|
Effects of simvastatin, a lipoprotein-lowering drug, on the hepatic enzymes involved in drug metabolism in the Wistar rat.
Topics: Animals; Body Weight; Enzyme Induction; Epoxide Hydrolases; Fatty Acids; Glycerolphosphate Dehydrogenase; Hypolipidemic Agents; In Vitro Techniques; Liver; Lovastatin; Male; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Phosphatidylcholines; Rats; Rats, Inbred Strains; Simvastatin; Subcellular Fractions | 1991 |
Phospholipid composition of high-density lipoproteins reflects lipolysis of triglyceride-rich lipoproteins during hyperlipidemia.
Topics: Adult; Anticholesteremic Agents; Cardiolipins; Cholesterol; Cholesterol, HDL; Fenofibrate; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipolysis; Lipoproteins, HDL; Lysophosphatidylcholines; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Simvastatin; Sphingomyelins; Triglycerides | 2001 |
Simultaneous quantification of simvastatin and excipients in liposomes using near infrared spectroscopy and chemometry.
Topics: Calibration; Cholesterol; Excipients; Least-Squares Analysis; Liposomes; Models, Theoretical; Phosphatidylcholines; Simvastatin; Spectroscopy, Near-Infrared | 2015 |
Curing the Toxicity of Multi-Walled Carbon Nanotubes through Native Small-molecule Drugs.
Topics: Animals; Humans; Mice; Nanotechnology; Nanotubes, Carbon; Oxidation-Reduction; Phosphatidylcholines; Simvastatin; Tissue Distribution | 2017 |
Interaction of statins with phospholipid bilayers studied by solid-state NMR spectroscopy.
Topics: Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Bilayers; Lovastatin; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phospholipids; Pravastatin; Simvastatin | 2019 |
Modulation of Phospholipid Bilayer Properties by Simvastatin.
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phospholipids; Simvastatin | 2021 |