phosphatidylcholines has been researched along with s-adenosylmethionine in 145 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (s-adenosylmethionine) | Trials (s-adenosylmethionine) | Recent Studies (post-2010) (s-adenosylmethionine) |
|---|---|---|---|---|---|
| 32,204 | 443 | 5,593 | 1,179 | 72 | 814 |
| 32,204 | 443 | 5,593 | 5,987 | 198 | 1,872 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 61 (42.07) | 18.7374 |
| 1990's | 20 (13.79) | 18.2507 |
| 2000's | 18 (12.41) | 29.6817 |
| 2010's | 37 (25.52) | 24.3611 |
| 2020's | 9 (6.21) | 2.80 |
| Authors | Studies |
|---|---|
| Chughtai, K; Glunde, K; Greenwood, TR; Heeren, RM; Jiang, L | 1 |
| Adamski, J; Boeing, H; Drogan, D; Floegel, A; Pischon, T; Prehn, C; Schulze, MB; von Ruesten, A | 1 |
| Eremina, OV; Khaustova, SA; Pavlovich, SV; Senyavina, NV; Tonevitsky, AG | 1 |
| Bakovic, M; Schenkel, LC; Sivanesan, S; Taylor, A; Verbrugghe, A; Wuyts, B; Zhang, J | 1 |
| Adams, SH; Gillingham, MB; Knotts, TA; Matern, D; McCoin, CS; Piccolo, BD; Vockley, J | 1 |
| Adamski, J; Ribič-Pucelj, M; Rižner, TL; Vouk, K | 1 |
| Chan, JF; Chow, WN; Curreem, SO; Ding, VS; Ho, DT; Hung, IF; Ke, TY; Lam, CW; Lau, SK; Lee, KC; Lo, GC; Sridhar, S; Sze, KH; To, KK; Wong, SC; Woo, PC; Yuen, KY | 1 |
| Arnhard, K; Bernhard, D; Danzl, K; Doppler, C; Dumfarth, J; Grimm, M; Heinz, K; Klavins, K; Koal, T; Messner, B; Oberacher, H; Pitterl, F; Stern, C | 1 |
| Fishman, D; Kingo, K; Okas, TL; Ottas, A; Soomets, U | 1 |
| Achaintre, D; Agnoli, C; Agudo, A; Ardanaz, E; Arriola, L; Bachlechner, U; Bamia, C; Boeing, H; Bueno-de-Mesquita, B; Carayol, M; Ferrari, P; Hansen, L; Huerta, JM; Jenab, M; Kaaks, R; Key, TJ; Khaw, KT; Kühn, T; Leitzmann, MF; Melander, O; Nilsson, J; Overvad, K; Palli, D; Panico, S; Peeters, PH; Quirós, JR; Rinaldi, S; Sánchez-Cantalejo, E; Scalbert, A; Schmidt, JA; Stepien, M; Tjønneland, A; Travis, RC; Trichopoulou, A; Tumino, R; Vineis, P; Wareham, N; Zamora-Ros, R | 1 |
| Adamski, J; Boeing, H; Floegel, A; Illig, T; Johnson, T; Kaaks, R; Kühn, T; Otto, W; Pischon, T; Prehn, C; Rolle-Kampczyk, U; Sookthai, D; von Bergen, M; Weikert, C | 1 |
| Bathe, OF; Buie, WD; Farshidfar, F; Hilsden, R; Kopciuk, KA; MacLean, A; Mazurak, VC; McGregor, SE; Vogel, HJ | 1 |
| Chadeau-Hyam, M; Chatzi, L; Keski-Rahkonen, P; Kogevinas, M; Nawrot, T; Pizzi, C; Plusquin, M; Richiardi, L; Robinot, N; Robinson, O; Scalbert, A; Sunyer, J; Vermeulen, R; Vineis, P; Vrijheid, M | 1 |
| Law, TH; Pan, Y; Volk, HA; Want, EJ; Zanghi, B | 1 |
| Auriola, S; Hanhineva, K; Heinonen, S; Jääskeläinen, T; Jokkala, J; Kärkkäinen, O; Laivuori, H; Lehtonen, M; Litonius, K | 1 |
| Costa, AC; Gattaz, WF; Joaquim, HPG; Serpa, MH; Talib, LL; Zanetti, MV | 1 |
| Baumann, S; Engel, KM; Grunewald, S; Rolle-Kampczyk, U; Schiller, J; von Bergen, M | 1 |
| Aslibekyan, S; Bagheri, M; Chamari, M; Djazayery, A; Farzadfar, F; Hassani, H; Koletzko, B; Qi, L; Uhl, O; Yekaninejad, MS | 1 |
| Boruczkowski, D; Pujal, JM; Zdolińska-Malinowska, I | 1 |
| Blanchet, O; Bocca, C; Boguenet, M; Bouet, PE; Chao de la Barca, JM; Chupin, S; El Hachem, H; May-Panloup, P; Reynier, P; Serri, O; Tessier, L | 1 |
| Chen, W; Gao, P; Guo, Y; Ji, W; Ke, M; Kong, D; Li, Y; Lin, L; Liu, P; Liu, S; Lu, J; Lu, Y; Lv, X; Qian, W; Shan, J; Shen, Q; Su, J; Wang, J; Wang, L; Zhu, Y | 1 |
| Bönhof, GJ; Knebel, B; Kotzka, J; Roden, M; Straßburger, K; Strom, A; Szendroedi, J; Ziegler, D | 1 |
| Abcouwer, SF; Afshinnia, F; Byun, J; Fort, PE; Gardner, TW; Kretzler, M; Looker, HC; Michailidis, G; Nelson, RG; Pennathur, S; Rajendiran, TM; Roger, JE; Shan, Y; Soni, T | 1 |
| Brennan, L; Ferreira, ALL; Fiamoncini, J; Freire, SDSR; Kac, G; Normando, P; Padilha, M; Yin, X | 1 |
| Axelrod, J; Diliberto, EJ; Hirata, F; Viveros, OH | 1 |
| Axelrod, J; Hirata, F; Strittmatter, WJ | 1 |
| Cheh, A; Dizikes, LJ; Lakowicz, JR; Rakow, S; Ridley, WP; Wood, JM | 1 |
| Schneider, WJ; Vance, DE | 1 |
| Mozzi, R; Porcellati, G | 1 |
| Kiss, Z | 1 |
| Axelrod, J; Hirata, F | 2 |
| Imai, Y; Inada, M; Kakimoto, H; Kawata, S; Matsuzawa, Y; Tarui, S | 1 |
| Long, JP; Sheff, KY; Yorek, MA | 1 |
| Dhalla, NS; Ganguly, PK; Panagia, V; Taira, Y; Tung, S | 1 |
| Betts, WH; French, JK; Hurst, NP | 1 |
| England, RE; Franks, JJ; Sastry, BV; Surber, MJ | 1 |
| Aylagas, H; Osada, J; Palacios-Alaiz, E | 1 |
| Bjur, RA; Greenhouse, AH; Mead, DJ; Reitz, RC; Welch, WH | 1 |
| Ozawa, K; Segawa, T | 1 |
| Audubert, F; Bereziat, G; Breton, M; Colard, O | 1 |
| Alarcon, RD; Kemp, B; Monti, JA; Morere, DA; Smythies, JR; Tolbert, LC; Walter-Ryan, WG | 1 |
| Jaffe, JJ; Srivastava, AK | 1 |
| Dhalla, NS; Ganguly, PK; Okumura, K; Panagia, V | 1 |
| Bloch, K; Chin, J | 1 |
| Hariyama, H; Moriguchi, K; Sato, H | 1 |
| Brasitus, TA; Dudeja, PK | 1 |
| Lakher, MB; Wurtman, RJ | 1 |
| Lakher, M; Wurtman, RJ | 1 |
| Dainous, F; Kanfer, JN | 1 |
| Bechet, JJ; Clauser, H; Drouva, SV; Kordon, C; LaPlante, E; Leblanc, P | 1 |
| Bloch, K; Chin, J; Kawasaki, S; Ramgopal, M | 1 |
| Brasitus, TA; Dudeja, PK; Foster, ES | 1 |
| Dhalla, NS; Ganguly, PK; Panagia, V | 2 |
| Borromei, A; Gaggi, R; Giancola, LC | 1 |
| Erickson, RP; Markovac, J | 1 |
| Young, DL | 1 |
| Thompson, W; Wong, ER | 1 |
| Kates, M; Marshall, MO | 1 |
| Abdel-Latif, AA; Morganstern, RD | 1 |
| Hallman, M; Raivio, K | 1 |
| Lester, RL; Waechter, CJ | 1 |
| Cobon, GS; Crowfoot, PD; Linnane, AW | 1 |
| Betzing, H; LeKim, D; Stoffel, W | 1 |
| Acheampong-Mensah, D; Feuer, G | 1 |
| Jensen, LS; Kushwaha, RP | 1 |
| Curri, SB | 1 |
| Adler, M; Cantoni, GL; Chiang, PK; de Blas, A; Nirenberg, M; Shih, M | 1 |
| Axelrod, J; Henneberry, RC; Hirata, F; Mallorga, P; Strittmatter, WJ; Tallman, JF | 1 |
| Cornatzer, WE; Haning, JA; Hoffman, DR | 3 |
| Bhattacharya, A; Vonderhaar, BK | 1 |
| Dhalla, NS; Ganguly, PK; Panagia, V; Rice, KM | 1 |
| Mato, JM; Traver, J; Varela, I | 1 |
| Alemany, S; Alvarez Chiva, V; García Gil, M; Marín Cao, D; Mato, JM; Varela, I | 1 |
| De Medio, GE; Porcellati, G; Porcellati, S; Stramentinoli, G; Trovarelli, G | 1 |
| Haraguchi, K; Hashizume, K; Ichikawa, K; Kobayashi, M; Yamada, T; Yamauchi, K | 1 |
| Fujiwara, M; Kumada, K; Mori, K; Nakazawa, K; Taniguchi, S | 1 |
| Janson, VE; Sastry, BV | 1 |
| Ansaldi, E; Chiappa, A; Massobrio, M | 1 |
| Moore, JF; Percy, AK; Waechter, CJ | 1 |
| Bartoli, E; Daino, L; Feo, F; Pascale, R; Pirisi, L; Satta, A; Zanetti, S | 1 |
| Higgins, JA | 1 |
| Akamatsu, Y; Maeda, M; Tanaka, Y | 1 |
| Cornatzer, WE; Hoffman, DR | 1 |
| Andreoli, V; Mozzi, R; Porcellati, G; Siepi, D | 1 |
| Axelrod, J; Hirata, F; Sastry, BV; Statham, CN | 1 |
| Axelrod, J; Crews, FT; Hirata, F | 1 |
| Appel, SH; Moore, RB | 1 |
| Denisova, NA; Kelly, JF; Kowatch, MA; Roth, GS | 1 |
| Giusto, NM; Roque, ME | 1 |
| Lasker, JM; Lieber, CS; Rosman, AS; Xin, Y | 1 |
| Panagia, V; Persad, S | 1 |
| Hayakawa, T; She, QB; Tsuge, H | 1 |
| Barry, JA; Gillies, RJ; Ross, BD | 1 |
| Lieber, CS | 3 |
| de Rudder, KE; Geiger, O; Thomas-Oates, JE | 1 |
| Brown, LA; Guidot, DM; Holguin, F; Moss, I | 1 |
| Colombo, C; Galli, C; Giulidori, P; Monti, S; Visioli, F | 1 |
| Alvaro, D; Attili, AF; Cantafora, A; Cardilli, A; Carli, L; Delle Monache, M; Fraioli, F; Gigliozzi, A; Romeo, R; Scafato, E | 1 |
| Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH | 1 |
| Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME | 1 |
| Bushma, MI; Karaedova, LM; Karpovich, VE; Khomich, TI; Konovalenko, OV; Lashak, LK; Legon'kova, LF; Zverinskiĭ, IV | 1 |
| Dhalla, NS; Kawabata, K; Nijjar, MS; Okumura, K; Panagia, V; Shah, KR; Tappia, PS | 1 |
| Gamsky, EA; Hicks, SM; Lehman-McKeeman, LD; Mar, MH; Vassallo, JD; Zeisel, SH | 1 |
| Pekhtashev, SG | 1 |
| Morita, T; Shimada, Y; Sugiyama, K | 1 |
| Boumann, HA; Chin, PT; De Kroon, AI; De Kruijff, B; Heck, AJ | 1 |
| Halsted, CH | 1 |
| Choi, JY; Mamoun, CB; Pessi, G; Reynolds, JM; Voelker, DR | 1 |
| Chen, AH; Davidson, AG; Innis, SM; James, SJ | 1 |
| Charlton, CG; Chen, H; Lee, ES; Soliman, KF | 1 |
| Brosnan, JT; Brosnan, ME; Jacobs, RL; Stead, LM; Vance, DE | 1 |
| Cao, Q; Lieber, CS; Mak, KM | 2 |
| Baldwin, CR; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Sorrell, MF; Tuma, DJ | 1 |
| Allen, RH; Brosnan, JT; Brosnan, ME; Jacobs, RL; Mudd, SH; Stabler, SP; Vance, DE; Wagner, C | 1 |
| Bottiglieri, T; Devlin, AM; Innis, SM; Lentz, SR; Singh, R; Wade, RE | 1 |
| Bobenchik, AM; Choi, JY; El Bissati, K; Hoch, JC; Mamoun, CB; Reynolds, JM; Takebe, S; Voelker, DR; Witola, WH | 1 |
| da Costa, KA; Fischer, LM; Sanders, LM; Zeisel, SH | 1 |
| Cheng, ML; Chiu, DT; Ho, HY; Shiao, MS; Tang, HY; Weng, SF | 1 |
| Finnegan, DM; Hansen, M; Hart, AC; Jacobs, RL; Jiang, K; Näär, AM; Niebergall, LJ; Rottiers, V; Shioda, T; Tzoneva, M; Vance, DE; Walker, AK; Watts, JL; Yang, F | 1 |
| Alberto, JM; Gkikopoulou, E; Guéant, JL; Marguerite, V; Merten, M | 1 |
| Cruz, D; Delgado, JM; Jiménez-Capdeville, ME; Ríos, R; Santoyo, ME; Zarazúa, S | 1 |
| Alonso, C; Aspichueta, P; Aurrekoetxea, I; Beraza, N; Buqué, X; Cano, A; Fernández-Ares, L; Finnell, RH; García-Rodríguez, JL; Lu, SC; Luka, Z; Martínez-Arranz, I; Martínez-Chantar, ML; Martínez-Uña, M; Mato, JM; Mestre, D; Varela-Rey, M; Wagner, C | 1 |
| Moresco, JJ; Rine, J; Sadhu, MJ; Yates, JR; Zimmer, AD | 1 |
| Butov, MA; Mnikhovich, MV; Nikiforov, AA; Uzbekova, DG; Vasilevskaia, AS | 1 |
| Lu, SC; Mato, JM; Noureddin, M | 1 |
| Ding, W; Hou, NS; Smulan, LJ; Taubert, S; Walker, AK; Watts, JL | 1 |
| Dvornichenko, VV; Morikov, DD; Morikova, EG | 1 |
| Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Walker, AK | 1 |
| Iwahashi, H; Kawachi, S; Matsuoka, H; Niu, L; Nomura, K; Suzuki, Y; Tamura, K | 1 |
| Kuang, Z; Sutter, BM; Tu, BP; Wang, Y; Ye, C | 1 |
| Byun, S; Guo, G; Kemper, B; Kemper, JK; Kim, YC; Kong, B; Ma, J; Seok, S; Xie, W; Zhang, Y | 1 |
| Feng, H; Gui, L; Li, N; Liu, Z; Ruan, M; Wan, JM; Wang, H; Zhang, H; Zhang, S | 1 |
| Elango, R | 1 |
| Mohmmed, A; Narwal, M; Sheokand, PK; Thakur, V | 1 |
| Fang, W; Tong, X; Yang, S; Ye, C; Zhu, Y | 1 |
| Aiba, T; Hara, S; Harada, S; Hirabayashi, T; Ikeda, K; Kaneko, M; Kasahara, K; Kawaguchi, M; Kikuchi, N; Kita, Y; Kiyonari, H; Kobayashi, T; Kurano, M; Mikami, K; Miki, Y; Mouri, M; Murakami, M; Nakata, R; Nishito, Y; Sato, H; Soga, T; Takamiya, R; Taketomi, Y; Tokuoka, SM; Yatomi, Y; Yoda, E; Yokoyama, K | 1 |
12 review(s) available for phosphatidylcholines and s-adenosylmethionine
| Article | Year |
|---|---|
Autologous cord blood in children with cerebral palsy: a review.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Brain Diseases; Brain Injuries; Carnitine; Cerebral Palsy; Child; Cytokines; Databases, Factual; Fetal Blood; Glycerol; Humans; Hypoxia; Hypoxia-Ischemia, Brain; Intercellular Signaling Peptides and Proteins; Phosphatidylcholines; Phosphorylcholine; Stem Cells; Succinic Acid | 2019 |
Mechanisms for the biomethylation of metals and metalloids.
Topics: Alkylmercury Compounds; Arsenic; Carbazoles; Cell Membrane Permeability; Metals; Methylation; Methylmercury Compounds; Organometallic Compounds; Phosphatidylcholines; Phosphatidylethanolamines; Pyrenes; S-Adenosylmethionine; Spectrometry, Fluorescence; Tetrahydrofolates; Vitamin B 12 | 1978 |
Phospholipid methylation and biological signal transmission.
Topics: Adrenal Medulla; Animals; Arachidonic Acids; Calcium; Cell Membrane; Chemotaxis, Leukocyte; Histamine Release; Lymphocyte Activation; Membrane Fluidity; Membrane Lipids; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Receptors, Adrenergic, beta; Receptors, Drug; S-Adenosylmethionine | 1980 |
[Fetal pulmonary maturity, II. Diagnosis].
Topics: Acid Phosphatase; Amniotic Fluid; Female; Fetal Organ Maturity; Humans; Hydrocortisone; Infant, Newborn; Lung; Phosphatidylcholines; Pregnancy; Prenatal Diagnosis; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; S-Adenosylmethionine; Sphingomyelins; Surface Tension | 1980 |
Comparison of new methods for measuring carbohydrate-deficient transferrin (CDT): application to a public health approach for the prevention of alcoholic cirrhosis.
Topics: Alcohol Drinking; Animals; Biomarkers; Blotting, Western; Chromatography, Ion Exchange; Humans; Isoelectric Focusing; Liver Cirrhosis, Alcoholic; Phosphatidylcholines; Radioimmunoassay; S-Adenosylmethionine; Transferrin | 1993 |
Herman Award Lecture, 1993: a personal perspective on alcohol, nutrition, and the liver.
Topics: Alcoholic Intoxication; Awards and Prizes; Ethanol; Humans; Liver; Liver Diseases, Alcoholic; Nutrition Disorders; Nutritional Physiological Phenomena; Phosphatidylcholines; S-Adenosylmethionine; Societies, Medical | 1993 |
Liver diseases by alcohol and hepatitis C: early detection and new insights in pathogenesis lead to improved treatment.
Topics: beta Carotene; Ethanol; Fatty Liver; Hepatitis C; Hepatitis, Alcoholic; Humans; Lipid Peroxidation; Liver Cirrhosis; NAD; Nutritional Status; Oxidative Stress; Phosphatidylcholines; S-Adenosylmethionine; Vitamin A | 2001 |
Nutrition and alcoholic liver disease.
Topics: Dietary Supplements; Enteral Nutrition; Humans; Liver Diseases, Alcoholic; Malnutrition; Parenteral Nutrition; Phosphatidylcholines; Prognosis; S-Adenosylmethionine | 2004 |
Pathogenesis and treatment of alcoholic liver disease: progress over the last 50 years.
Topics: Animals; Antioxidants; History, 20th Century; History, 21st Century; Humans; Liver Diseases, Alcoholic; Phosphatidylcholines; S-Adenosylmethionine; Silymarin | 2005 |
Nonalcoholic fatty liver disease: update on pathogenesis, diagnosis, treatment and the role of S-adenosylmethionine.
Topics: Animals; Biomarkers; Disease Models, Animal; Humans; Liver; Mice; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine; United States | 2015 |
1-Carbon Cycle Metabolites Methylate Their Way to Fatty Liver.
Topics: Animals; Carbon Cycle; Diabetes Mellitus, Type 2; Fatty Liver; Humans; Lipogenesis; Phosphatidylcholines; S-Adenosylmethionine | 2017 |
Methionine Nutrition and Metabolism: Insights from Animal Studies to Inform Human Nutrition.
Topics: Animals; Betaine; Choline; Creatine; Cysteine; Diet; Folic Acid; Glutathione; Homocysteine; Humans; Methionine; Methylation; Models, Animal; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; S-Adenosylmethionine; Sulfur | 2020 |
3 trial(s) available for phosphatidylcholines and s-adenosylmethionine
| Article | Year |
|---|---|
Metabolic perturbations associated with the consumption of a ketogenic medium-chain TAG diet in dogs with idiopathic epilepsy.
Topics: Animals; Anticonvulsants; Carnitine; Chromatography, Liquid; Cross-Over Studies; Diet; Diet, Ketogenic; Dog Diseases; Dogs; Epilepsy; Fasting; Fatty Acids; Female; Lipid Metabolism; Lipids; Male; Mass Spectrometry; Metabolome; Phosphatidylcholines; Placebos; Triglycerides | 2018 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans.
Topics: Adolescent; Adult; Aged; Biomarkers; Cholesterol, Dietary; Choline; Choline Deficiency; Docosahexaenoic Acids; Female; Genetic Association Studies; Humans; Liver; Male; Menopause; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Polymorphism, Single Nucleotide; S-Adenosylhomocysteine; S-Adenosylmethionine; Young Adult | 2011 |
130 other study(ies) available for phosphatidylcholines and s-adenosylmethionine
| Article | Year |
|---|---|
Mass spectrometry images acylcarnitines, phosphatidylcholines, and sphingomyelin in MDA-MB-231 breast tumor models.
Topics: Animals; Breast Neoplasms; Carnitine; Cell Line, Tumor; Cell Transformation, Neoplastic; Humans; Mass Spectrometry; Mice; Molecular Imaging; Phosphatidylcholines; Sphingomyelins | 2013 |
Variation of serum metabolites related to habitual diet: a targeted metabolomic approach in EPIC-Potsdam.
Topics: Adult; Amino Acids; Carnitine; Chronic Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet; Feeding Behavior; Female; Hexoses; Humans; Male; Metabolome; Metabolomics; Middle Aged; Phosphatidylcholines; Risk Factors; Surveys and Questionnaires | 2013 |
Serum metabolic profiles of pregnant women with burdened obstetrical history.
Topics: Abortion, Spontaneous; Amino Acids; Biomarkers; Carnitine; Case-Control Studies; Female; Hexoses; Humans; Phosphatidylcholines; Pregnancy; Sphingomyelins | 2013 |
Choline supplementation restores substrate balance and alleviates complications of Pcyt2 deficiency.
Topics: Acylation; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Carnitine; Choline; Dietary Supplements; Fatty Acids; Gene Expression Regulation; Liver; Mice, Mutant Strains; Phosphatidylcholines; Phosphatidylserines; RNA Nucleotidyltransferases; Triglycerides; Weight Gain | 2015 |
Unique plasma metabolomic signatures of individuals with inherited disorders of long-chain fatty acid oxidation.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Adolescent; Carnitine; Carnitine O-Palmitoyltransferase; Case-Control Studies; Ceramides; Fatty Acids; Female; Humans; Lipid Metabolism; Lipid Metabolism, Inborn Errors; Male; Metabolic Networks and Pathways; Metabolism, Inborn Errors; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylethanolamines; Plasma; Sphingomyelins; Triglycerides | 2016 |
Altered levels of acylcarnitines, phosphatidylcholines, and sphingomyelins in peritoneal fluid from ovarian endometriosis patients.
Topics: Adult; Area Under Curve; Biomarkers; Carnitine; Case-Control Studies; Endometriosis; Female; Humans; Peritoneum; Phosphatidylcholines; ROC Curve; Sphingomyelins | 2016 |
Metabolomic Profiling of Plasma from Melioidosis Patients Using UHPLC-QTOF MS Reveals Novel Biomarkers for Diagnosis.
Topics: Bacteremia; Biomarkers; Carnitine; Case-Control Studies; Humans; Melioidosis; Metabolome; Phosphatidylcholines; Sphingomyelins | 2016 |
Metabolomic profiling of ascending thoracic aortic aneurysms and dissections - Implications for pathophysiology and biomarker discovery.
Topics: Adult; Aged; Amino Acids; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Biomarkers; Carnitine; Case-Control Studies; Ceramides; Female; Hexoses; Humans; Lysophosphatidylcholines; Male; Metabolomics; Middle Aged; Phosphatidylcholines; Sphingomyelins; Young Adult | 2017 |
The metabolic analysis of psoriasis identifies the associated metabolites while providing computational models for the monitoring of the disease.
Topics: Adult; Aged; Alkanes; Amino Acids; Carnitine; Computer Simulation; Dicarboxylic Acids; Female; Humans; Male; Metabolome; Middle Aged; Phosphatidylcholines; Phytol; Psoriasis; Urea; Young Adult | 2017 |
Blood Metabolic Signatures of Body Mass Index: A Targeted Metabolomics Study in the EPIC Cohort.
Topics: Adult; Amino Acids; Bile Duct Neoplasms; Biogenic Amines; Blood Proteins; Body Mass Index; Carcinoma; Carnitine; Case-Control Studies; Diabetes Mellitus; Europe; Gene Expression; Hexoses; Humans; Linear Models; Liver Neoplasms; Longitudinal Studies; Male; Metabolome; Middle Aged; Nutrition Assessment; Obesity; Phosphatidylcholines; Risk Factors; Sphingomyelins | 2017 |
Serum metabolites and risk of myocardial infarction and ischemic stroke: a targeted metabolomic approach in two German prospective cohorts.
Topics: Aged; Amino Acids; Biomarkers; Brain Ischemia; Carnitine; Female; Germany; Humans; Incidence; Male; Metabolomics; Middle Aged; Myocardial Infarction; Phosphatidylcholines; Prospective Studies; Risk Factors; Serum; Stroke; Triglycerides | 2018 |
A quantitative multimodal metabolomic assay for colorectal cancer.
Topics: Adenoma; Aged; Amino Acids; Biomarkers, Tumor; Carnitine; Colorectal Neoplasms; Early Detection of Cancer; Female; Humans; Male; Mass Spectrometry; Metabolome; Metabolomics; Middle Aged; Phosphatidylcholines; Sphingomyelins | 2018 |
Cord Blood Metabolic Signatures of Birth Weight: A Population-Based Study.
Topics: Birth Weight; Carnitine; Chromatography, High Pressure Liquid; Cohort Studies; Docosahexaenoic Acids; Environmental Exposure; Europe; Female; Fetal Blood; Fetal Development; Fetus; Humans; Indoles; Infant, Newborn; Male; Mass Spectrometry; Metabolome; Particulate Matter; Phosphatidylcholines; Pregnancy; Progesterone; Prostaglandins; Reference Standards; Tryptophan; Vitamin A | 2018 |
A Non-Targeted LC-MS Profiling Reveals Elevated Levels of Carnitine Precursors and Trimethylated Compounds in the Cord Plasma of Pre-Eclamptic Infants.
Topics: Adult; Biomarkers; Carnitine; Case-Control Studies; Chromatography, Liquid; Creatine; Cross-Sectional Studies; Female; Fetal Blood; Humans; Infant, Newborn; Metabolomics; Phosphatidylcholines; Pre-Eclampsia; Pregnancy; Principal Component Analysis; Putrescine; Pyridoxic Acid; Tandem Mass Spectrometry; Tryptophan; Urea | 2018 |
Plasma metabolites in first episode psychoses.
Topics: Adolescent; Adult; Biomarkers; Bipolar Disorder; Carnitine; Female; Humans; Lysophosphatidylcholines; Male; Phosphatidylcholines; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Young Adult | 2019 |
Metabolomic profiling reveals correlations between spermiogram parameters and the metabolites present in human spermatozoa and seminal plasma.
Topics: Adult; Amino Acids; Biogenic Amines; Carnitine; Centrifugation, Density Gradient; Gas Chromatography-Mass Spectrometry; Humans; Lysophosphatidylcholines; Male; Metabolome; Phosphatidylcholines; Semen; Semen Analysis; Spermatozoa; Sphingomyelins; Sugars | 2019 |
Plasma metabolomic profiling of amino acids and polar lipids in Iranian obese adults.
Topics: Adult; Alcohol Drinking; Amino Acids; Biomarkers; Body Mass Index; Carnitine; Case-Control Studies; Chromatography, Liquid; Exercise; Female; Humans; Iran; Linear Models; Lysophospholipids; Male; Metabolome; Metabolomics; Obesity; Phosphatidylcholines; Smoking; Sphingomyelins; Tandem Mass Spectrometry | 2019 |
Metabolomic signature of the seminal plasma in men with severe oligoasthenospermia.
Topics: Adult; Amines; Amino Acids; Carnitine; Fatty Acids, Unsaturated; Humans; Male; Metabolome; Metabolomics; Oligospermia; Phosphatidylcholines; Prospective Studies; Semen; Semen Analysis; Sperm Motility; Spermatozoa; Sphingomyelins | 2020 |
Untargeted lipidomics reveals specific lipid abnormalities in Sjögren's syndrome.
Topics: Biomarkers; Carnitine; Case-Control Studies; Chromatography, High Pressure Liquid; Discriminant Analysis; Female; Humans; Lipidomics; Male; Mass Spectrometry; Phosphatidylcholines; Sensitivity and Specificity; Sjogren's Syndrome; Triglycerides | 2021 |
Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes.
Topics: Adult; Autonomic Nervous System Diseases; Carnitine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dyslipidemias; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Heart Rate; Humans; Insulin Resistance; Lipid Metabolism; Lipidomics; Lysophosphatidylcholines; Male; Middle Aged; Obesity; Phosphatidylcholines; Sphingomyelins; Young Adult | 2021 |
Diminished retinal complex lipid synthesis and impaired fatty acid β-oxidation associated with human diabetic retinopathy.
Topics: Adult; Aged; American Indian or Alaska Native; Arizona; Black or African American; Carnitine; Case-Control Studies; Ceramides; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Diglycerides; Disease Progression; Esters; Female; Hispanic or Latino; Humans; Lipidomics; Male; Mass Spectrometry; Middle Aged; Mitochondria; Phosphatidylcholines; Retina; Triglycerides; White People | 2021 |
Prepregnancy Body Mass Index and Lipoprotein Fractions are Associated with Changes in Women's Serum Metabolome from Late Pregnancy to the First Months of Postpartum.
Topics: Amino Acids; Biogenic Amines; Body Mass Index; Cholesterol; Female; Humans; Lipoproteins; Metabolome; Metabolomics; Phosphatidylcholines; Postpartum Period; Pregnancy; Prospective Studies; Sphingomyelins | 2023 |
Identification and properties of two methyltransferases in conversion of phosphatidylethanolamine to phosphatidylcholine.
Topics: Adrenal Medulla; Animals; Cattle; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methyltransferases; Microsomes; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine | 1978 |
Phospholipid methylation unmasks cryptic beta-adrenergic receptors in rat reticulocytes.
Topics: Animals; Erythrocyte Membrane; Erythrocytes; Membrane Lipids; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes; S-Adenosylmethionine | 1979 |
Conversion of phosphatidylethanolamine to phosphatidylcholine in rat liver. Partial purification and characterization of the enzymatic activities.
Topics: Animals; Kinetics; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1979 |
Conversion of phosphatidylethanolamine to phosphatidylcholine in rat brain by the methylation pathway.
Topics: Animals; Brain; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1979 |
Role of a specific choline pool in sphingomyelin synthesis in rat heart.
Topics: Animals; Choline; Ethanolamines; In Vitro Techniques; Kinetics; Male; Myocardium; Phosphatidylcholines; Phospholipids; Phosphorus; Rats; S-Adenosylmethionine; Sphingomyelins; Tissue Distribution | 1977 |
Enzymatic methylation of phosphatidylethanolamine increases erythrocyte membrane fluidity.
Topics: Animals; Cytoplasm; Erythrocyte Membrane; Erythrocytes; Male; Membrane Fluidity; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Temperature | 1978 |
Changes in lipid composition of erythrocyte membranes with administration of S-adenosyl-L-methionine in chronic liver disease.
Topics: Adult; Aged; Cholesterol; Chronic Disease; Erythrocyte Membrane; Female; Humans; Injections, Intravenous; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male; Membrane Fluidity; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylmethionine | 1992 |
Hemicholinium-3 derivatives A-4 and A-5 alter choline metabolism in NB41A3 neuroblastoma cells.
Topics: Animals; Biphenyl Compounds; Choline; Ethanolamine; Ethanolamines; Mice; Neuroblastoma; Phosphatidylcholines; Phospholipids; Piperidines; S-Adenosylmethionine; Tumor Cells, Cultured | 1991 |
Alterations in phospholipid N-methylation of cardiac subcellular membranes due to experimentally induced diabetes in rats.
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Transporting ATPases; Diabetes Mellitus, Experimental; Male; Methylation; Methyltransferases; Mitochondria, Heart; Myocardium; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sarcolemma; Sarcoplasmic Reticulum | 1990 |
Phorbol 12-myristate 13-acetate, A23187 and L-adrenaline inhibit phospholipid methylation in human monocytes and lymphocytes. Inhibition is independent of oxyradical production and phospholipid hydrolysis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Epinephrine; Free Radicals; Humans; Hydrolysis; Isoquinolines; Lymphocytes; Methylation; Monocytes; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Piperazines; Protein Kinase Inhibitors; S-Adenosylmethionine; Sodium Fluoride; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Halothane and isoflurane alter phospholipid transmethylation in rat brain synaptosomes.
Topics: Animals; Brain; Halothane; In Vitro Techniques; Isoflurane; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Synaptosomes | 1990 |
Effects of S-adenosyl-L-methionine on phospholipid methyltransferase activity changes induced by thioacetamide.
Topics: Acetamides; Animals; Liver; Male; Methyltransferases; Microsomes, Liver; Necrosis; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Thioacetamide | 1990 |
Phosphatidylethanolamine N-methyltransferase in human red blood cell membrane preparations. Kinetic mechanism.
Topics: Adult; Erythrocyte Membrane; Humans; Kinetics; Male; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Histamine increases phospholipid methylation and H2-receptor-adenylate cyclase coupling in rat brain.
Topics: Adenylyl Cyclases; Animals; Brain; Cyclic AMP; Enzyme Activation; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; Receptors, Histamine H2; S-Adenosylhomocysteine; S-Adenosylmethionine; Synaptic Membranes; Tissue Distribution | 1988 |
Differential methylation patterns in molecular species of phosphatidylethanolamine derivatives in rat liver membranes.
Topics: Animals; Chromatography, Gas; Chromatography, High Pressure Liquid; Fatty Acids; Female; Intracellular Membranes; Methylation; Microsomes, Liver; Molecular Structure; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1989 |
One-carbon metabolism disturbances in affective disorders. A preliminary report.
Topics: Bipolar Disorder; Depressive Disorder; Erythrocytes; Folic Acid; Humans; Kinetics; Methionine Adenosyltransferase; Phosphatidylcholines; S-Adenosylmethionine; Schizophrenia; Transferases | 1985 |
Phosphatidylcholine synthesis in adult Dirofilaria immitis females.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Dirofilaria immitis; Female; Filarioidea; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine | 1985 |
Activation of Ca2+-stimulated ATPase by phospholipid N-methylation in cardiac sarcoplasmic reticulum.
Topics: Animals; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Cell-Free System; Enzyme Activation; Imidoesters; Membrane Lipids; Methylation; Myocardium; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Sarcoplasmic Reticulum | 1985 |
Phosphatidylcholine synthesis in yeast.
Topics: Choline; Cytidine Diphosphate Choline; Ethionine; Methionine; Methylation; Mutation; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine; Saccharomyces cerevisiae | 1988 |
S-adenosyl-L-methionine protects the hippocampal CA1 neurons from the ischemic neuronal death in rat.
Topics: Animals; Cell Membrane; Cell Survival; Cytidine Diphosphate Choline; Hippocampus; Ischemic Attack, Transient; Male; Methionine; Methylation; Necrosis; Nerve Degeneration; Neurons; Phosphatidylcholines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1988 |
Identification and partial characterization of phospholipid methylation in rat small-intestinal brush-border membranes.
Topics: Animals; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestine, Small; Male; Methylation; Microvilli; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylmethionine | 1987 |
Molecular composition of the phosphatidylcholines produced by the phospholipid methylation pathway in rat brain in vivo.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Fatty Acids; Male; Methionine; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1987 |
In vivo synthesis of phosphatidylcholine in rat brain via the phospholipid methylation pathway.
Topics: Animals; Brain; Injections, Intraventricular; Male; Methylation; Phosphatidylcholines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Subcellular Fractions | 1987 |
Effect of modification of membrane phospholipid composition on phospholipid methylation in aggregating cell culture.
Topics: Animals; Brain; Cell Aggregation; Cells, Cultured; Deanol; Ethanolamines; Membrane Lipids; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylmethionine | 1986 |
Estradiol activates methylating enzyme(s) involved in the conversion of phosphatidylethanolamine to phosphatidylcholine in rat pituitary membranes.
Topics: Animals; Cell Compartmentation; Cell Membrane; Enzyme Activation; Estradiol; Female; Hydrogen-Ion Concentration; Hypothalamo-Hypophyseal System; Kinetics; Magnesium; Methylation; Methyltransferases; Ovariectomy; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Pituitary Gland; Rats; S-Adenosylmethionine; Tissue Distribution | 1986 |
Sterol control of the phosphatidylethanolamine-phosphatidylcholine conversion in the yeast mutant GL7.
Topics: Adenosine Triphosphate; Amphotericin B; Cell Membrane; Cholesterol; Ergosterol; Filipin; Methylation; Methyltransferases; Mutation; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phosphorylation; S-Adenosylmethionine; Saccharomyces cerevisiae | 1985 |
Synthesis of phosphatidylcholine by two distinct methyltransferases in rat colonic brush-border membranes: evidence for extrinsic and intrinsic membrane activities.
Topics: Adenosine Triphosphate; Animals; Cations, Divalent; Colon; In Vitro Techniques; Intestinal Mucosa; Male; Methylation; Methyltransferases; Microvilli; Octoxynol; Phosphatidylcholines; Phospholipids; Polyethylene Glycols; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Subcellular Fractions; Temperature; Time Factors | 1986 |
Evidence for three catalytic sites in heart sarcolemmal phospholipid N-methylation.
Topics: Animals; Catalysis; Chemical Phenomena; Chemistry; Kinetics; Magnesium; Male; Methylation; Methyltransferases; Myocardium; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sarcolemma | 1985 |
Involutional dementias: new perspectives.
Topics: Aged; Dementia; Drug Therapy, Combination; Humans; Middle Aged; Neurocognitive Disorders; Phosphatidylcholines; Piracetam; Pyrrolidinones; S-Adenosylmethionine | 1985 |
A component of genetic variation among mice in activity of transmembrane methyltransferase I determined by the H-2 region.
Topics: Animals; Cell Membrane; Genetic Variation; H-2 Antigens; Liver; Methyltransferases; Mice; Mice, Inbred Strains; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine | 1985 |
Estradiol- and testosterone-induced alterations in phosphatidylcholine and triglyceride synthesis in hepatic endoplasmic reticulum.
Topics: Acyltransferases; Animal Nutritional Physiological Phenomena; Animals; Benzoates; Body Weight; Carbon Isotopes; Castration; Choline; Coenzyme A; Cytosine Nucleotides; Depression, Chemical; Diet; Endoplasmic Reticulum; Estradiol; Female; Glycerides; Injections, Subcutaneous; Lipotropic Agents; Liver; Male; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phosphotransferases; Propionates; Rats; S-Adenosylmethionine; Stimulation, Chemical; Testosterone; Triglycerides | 1971 |
Choline oxidation and labile methyl groups in normal and choline-deficient rat liver.
Topics: Acetates; Alcohol Oxidoreductases; Aldehydes; Animals; Autoradiography; Betaine; Carbon Isotopes; Choline; Choline Deficiency; Chromatography; Fatty Acids, Nonesterified; Kinetics; Liver; Male; Methionine; Methylation; Mitochondria, Liver; NAD; Oxidoreductases; Phosphatidylcholines; Rats; S-Adenosylmethionine; Serotonin; Subcellular Fractions; Triglycerides; Tritium | 1972 |
Biosynthesis of nitrogenous phospholipids in spinach leaves.
Topics: Calcium; Carbon Radioisotopes; Carboxy-Lyases; Choline; Chromatography; Chromatography, Paper; Chromatography, Thin Layer; Cytosine Nucleotides; Escherichia coli; Ethanolamines; Microsomes; Phosphatidylcholines; Phosphatidylethanolamines; Plant Cells; Plants; S-Adenosylmethionine; Serine; Silicon Dioxide; Transferases; Ultrasonics | 1974 |
Incorporation of (14-C) ethanolamine and (3-H) methionine into phospholipids of rat brain and liver in vivo and in vitro.
Topics: Animals; Brain; Carbon Radioisotopes; Choline; Ethanolamines; In Vitro Techniques; Inositol; Liver; Male; Methionine; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Rats; S-Adenosylmethionine; Sphingomyelins; Synaptosomes; Tritium | 1974 |
Studies on the biosynthesis of disaturated lecithin of the lung: the importance of the lysolecithin pathway.
Topics: Animals; Carbon Radioisotopes; Choline; Female; Glycerol; Isotope Labeling; Lung; Lysophosphatidylcholines; Palmitic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Pulmonary Surfactants; Rabbits; S-Adenosylmethionine; Time Factors; Tritium | 1974 |
Differential regulation of the N-methyl transferases responsible for phosphatidylcholine synthesis in Saccharomyces cerevisiae.
Topics: Carbon Isotopes; Cell-Free System; Choline; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Culture Media; Ethanolamines; Fatty Acids; Kinetics; Methyltransferases; Phosphatidylcholines; Phospholipids; Phosphorus Isotopes; S-Adenosylmethionine; Saccharomyces cerevisiae; Time Factors | 1973 |
Biogenesis of mitchondria. Phospholipid synthesis in vitro by yeast mitochondrial and microsomal fractions.
Topics: Chromatography, Thin Layer; Cytidine Diphosphate Choline; Glycerophosphates; In Vitro Techniques; Microsomes; Mitochondria; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; S-Adenosylmethionine; Saccharomyces cerevisiae; Subcellular Fractions | 1974 |
Studies in vivo and in vitro on the methylation of phosphatidyl-N,N-dimethylethanolamine to phosphatidylcholine in rat liver.
Topics: Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Endoplasmic Reticulum; Isotope Labeling; Liver; Methylation; Methyltransferases; Organ Specificity; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Time Factors; Tritium | 1973 |
Relation between the hepatic action of drugs and the synthesis of subcellular structures.
Topics: Aminopyrine N-Demethylase; Analysis of Variance; Animals; Choline; Dactinomycin; Deficiency Diseases; Diet; Drug Interactions; In Vitro Techniques; Liver; Male; Methionine; Methylation; Methyltransferases; Microsomes, Liver; Phenobarbital; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Biosynthesis; Rats; S-Adenosylmethionine; Subcellular Fractions | 1974 |
In vivo and in vitro utilization of labeled precursors for choline synthesis in mature Japanese quail as compared to rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Radioisotopes; Chickens; Choline; Coturnix; Ethanolamines; Female; In Vitro Techniques; Liver; Methionine; Methylamines; Methylation; Methyltransferases; Nutritional Requirements; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylmethionine; Serine; Species Specificity | 1974 |
[Transmethylation processes in senile involution: a working hypothesis].
Topics: Adenine; Aging; Arteriosclerosis; Catecholamines; DNA; Humans; Lipoproteins; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phospholipids; RNA; S-Adenosylmethionine; Vitamin B 12 | 1971 |
Inhibitors of CDP-choline synthesis, action potential calcium channels, and stimulus-secretion coupling.
Topics: Acetylcholine; Action Potentials; Animals; Calcium; Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Deoxyadenosines; Hybrid Cells; Ion Channels; Mice; Motor Endplate; Nucleotidyltransferases; Phosphatidylcholines; Rats; Receptors, Nicotinic; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides; Tubercidin | 1984 |
Regulation of beta-adrenergic receptors by phospholipid methylation.
Topics: Adenylyl Cyclases; Animals; Anura; Cell Membrane; Cyclic AMP; Humans; Membrane Lipids; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipids; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; S-Adenosylmethionine | 1980 |
Effects of a methyl-deficient diet on rat liver phosphatidylcholine biosynthesis.
Topics: Animals; Choline Deficiency; Diacylglycerol Cholinephosphotransferase; Diet; Female; Liver; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
Membrane modification differentially affects the binding of the lactogenic hormones human growth hormone and ovine prolactin.
Topics: Animals; Cell Membrane; Cells, Cultured; Female; Growth Hormone; Humans; Lactation; Mammary Glands, Animal; Membrane Lipids; Methylation; Mice; Phosphatidylcholines; Pregnancy; Prolactin; Receptors, Cell Surface; S-Adenosylmethionine | 1981 |
Effect of Friend virus infection on the biosynthetic enzymes of phosphatidylcholine biosynthesis in spleen microsomes.
Topics: Animals; Diacylglycerol Cholinephosphotransferase; Friend murine leukemia virus; Leukemia, Experimental; Male; Methylation; Mice; Mice, Inbred BALB C; Microsomes; Phosphatidylcholines; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 1984 |
Sarcolemmal phosphatidylethanolamine N-methylation in diabetic cardiomyopathy.
Topics: Animals; Cardiomyopathies; Diabetes Mellitus, Experimental; Kinetics; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcolemma | 1984 |
Effect of exogenous S-adenosyl-L-methionine on phosphatidylcholine synthesis by isolated rat hepatocytes.
Topics: Animals; Deoxyadenosines; Dose-Response Relationship, Drug; In Vitro Techniques; Liver; Methylation; Phosphatidylcholines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Thionucleosides; Tubercidin | 1984 |
[Hormonal regulation of the synthesis of phosphatidylcholine by transmethylation].
Topics: Animals; Hormones; Humans; Liver; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1983 |
The effect of S-Adenosyl-L-methionine on ischemia-induced disturbances of brain phospholipid in the gerbil.
Topics: Animals; Brain; Brain Ischemia; Diglycerides; Gerbillinae; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Plasmalogens; S-Adenosylmethionine | 1983 |
Characterization of heart sarcolemmal phospholipid methylation.
Topics: Animals; Calcium; Kinetics; Magnesium; Male; Methyltransferases; Myocardium; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Potassium; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Sarcolemma; Sodium | 1984 |
Evidence for the existence of protein inhibitors for S-adenosyl-L-methionine-mediated methylation of phosphatidylethanolamine in rat liver cytosol.
Topics: Animals; Cell Membrane; Cytosol; In Vitro Techniques; Liver; Male; Methylation; Microsomes, Liver; Mitochondria, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1983 |
Enzymatic properties of phospholipid methylation in rabbit platelets.
Topics: Animals; Blood Platelets; Buffers; Calcium; Cations, Divalent; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rabbits; S-Adenosylmethionine | 1983 |
Depression of human sperm motility by inhibition of enzymatic methylation.
Topics: Adult; Humans; Male; Membrane Fluidity; Membrane Lipids; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine; Sperm Motility; Spermatozoa | 1983 |
Properties of particulate and detergent-solubilized phospholipid N-methyltransferase activity from calf brain.
Topics: Animals; Brain; Cattle; Kinetics; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine; Solubility; Taurocholic Acid | 1982 |
Role of phosphatidylethanolamine methylation in the synthesis of phosphatidylcholine by hepatocytes isolated from choline-deficient rats.
Topics: Animals; Choline; Choline Deficiency; In Vitro Techniques; Lipoproteins; Liver; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Triglycerides | 1982 |
Biogenesis of endoplasmic reticulum phosphatidylcholine. Translocation of intermediates across the membrane bilayer during methylation of phosphatidylethanolamine.
Topics: Animals; Carbon Radioisotopes; Endoplasmic Reticulum; Kinetics; Lipid Bilayers; Male; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Taurocholic Acid; Trypsin; Type C Phospholipases | 1981 |
Presence of the phospholipid methylation pathway in mammalian cultured cells.
Topics: Animals; Cells, Cultured; Liver; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine | 1981 |
Microsomal phosphatidylethanolamine methyltransferase: some physical and kinetic properties.
Topics: Animals; Detergents; Female; Guinea Pigs; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; S-Adenosylmethionine | 1981 |
Microsomal phosphatidylethanolamine methyltransferase: inhibition by S-adenosylhomocysteine.
Topics: Animals; Female; Guinea Pigs; Homocysteine; Kinetics; Methyltransferases; Mice; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rabbits; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1981 |
The synthesis of choline plasmalogen by the methylation pathway in rat brain.
Topics: Animals; Brain; Male; Methylation; Microsomes; Phosphatidylcholines; Plasmalogens; Rats; S-Adenosylmethionine | 1981 |
Evidence for two methyltransferase involved in the conversion of phosphatidylethanolamine to phosphatidylcholine in the rat liver.
Topics: Animals; Kinetics; Male; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; S-Adenosylmethionine; Subcellular Fractions | 1981 |
Identification and properties of methyltransferases that synthesize phosphatidylcholine in rat brain synaptosomes.
Topics: Animals; Brain; Hydrogen-Ion Concentration; Kinetics; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Rats; S-Adenosylmethionine; Subcellular Fractions; Synaptosomes | 1980 |
Methylation of erythrocyte membrane phospholipids in patients with myotonic and Duchenne muscular dystrophy.
Topics: Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Membrane Lipids; Methylation; Muscular Dystrophies; Phosphatidylcholines; Phospholipids; S-Adenosylmethionine | 1980 |
Partial restoration of impaired alpha 1-adrenergic responsiveness in parotid cells of aged rats by S-adenosylmethionine treatment.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Aging; Animals; Fluorescence Polarization; Inositol 1,4,5-Trisphosphate; Male; Membrane Fluidity; Membrane Lipids; Methylation; Parotid Gland; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Viscosity | 1995 |
Phosphatidylethanolamine N-methyltransferase activity in isolated rod outer segments from bovine retina.
Topics: Animals; Cattle; Electron Transport Complex IV; Fatty Acids; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methyltransferases; NADH Dehydrogenase; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rod Cell Outer Segment; S-Adenosylmethionine | 1995 |
Abnormal synthesis of N-methylated phospholipids during calcium paradox of the heart.
Topics: Animals; Calcium; Heart; In Vitro Techniques; Kinetics; Male; Methylation; Methyltransferases; Mitochondria, Heart; Myocardial Contraction; Myocardium; Perfusion; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Sarcolemma; Sarcoplasmic Reticulum | 1995 |
Alteration in the phosphatidylcholine biosynthesis of rat liver microsomes caused by vitamin B6 deficiency.
Topics: Animals; Caseins; Choline; Choline Kinase; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Diacylglycerol Cholinephosphotransferase; Liver; Male; Methylation; Methyltransferases; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 6 Deficiency | 1995 |
In vitro and in vivo 13C and 31P NMR analyses of phosphocholine metabolism in rat glioma cells.
Topics: Animals; Carbon Isotopes; Cell Division; Choline; Ethanolamines; Glioma; Magnetic Resonance Spectroscopy; Methionine; Organophosphorus Compounds; Phosphatidylcholines; Phosphatidylserines; Phosphorus Isotopes; Phosphorylcholine; Rats; Rats, Inbred F344; S-Adenosylmethionine; Tumor Cells, Cultured | 1994 |
Rhizobium meliloti mutants deficient in phospholipid N-methyltransferase still contain phosphatidylcholine.
Topics: Acetates; Chromatography, Thin Layer; Culture Media; Lipid Metabolism; Lipids; Mass Spectrometry; Methylnitronitrosoguanidine; Methyltransferases; Mutagenesis; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine; Sinorhizobium meliloti | 1997 |
Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotoxin-mediated acute edematous lung injury in rats.
Topics: Acetylcysteine; Acute Disease; Alcohol Drinking; Animals; Bacterial Toxins; Bronchoalveolar Lavage Fluid; Causality; Cell Survival; Chemotherapy, Cancer, Regional Perfusion; Endotoxins; Ethanol; Glutathione; Homeostasis; Lung; Lung Injury; Male; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1998 |
S-adenosyl-L-methionine: role in phosphatidylcholine synthesis and in vitro effects on the ethanol-induced alterations of lipid metabolism.
Topics: Acetates; Carbon Radioisotopes; Esterification; Ethanol; Glycerol; Humans; Lipid Metabolism; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Triglycerides; Tritium; Tumor Cells, Cultured | 1998 |
Effect of S-adenosyl-L-methionine and dilinoleoylphosphatidylcholine on liver lipid composition and ethanol hepatotoxicity in isolated perfused rat liver.
Topics: Animals; Bile; Cholesterol; Ethanol; Glutathione; In Vitro Techniques; Lipids; Liver; Male; Microsomes, Liver; Oxygen Consumption; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Wistar; S-Adenosylmethionine | 1998 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; Homocysteine; Humans; Infant; Infant, Newborn; Male; Methionine; Methylation; Phosphatidylcholines; S-Adenosylmethionine; Seizures; Serine; Tetrahydrofolates | 1998 |
[Inhibition of the antioxidant protection, microsomal oxidation, and xenobiotic glucuroconjugation in rats with cholestasis and their regulation].
Topics: Animals; Antioxidants; Cholestasis; Glucuronates; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Nikethamide; Oxidation-Reduction; Phosphatidylcholines; Rats; S-Adenosylmethionine; Ursodeoxycholic Acid; Xenobiotics | 1999 |
Ca2+-antagonists inhibit the N-methyltransferase-dependent synthesis of phosphatidylcholine in the heart.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Diltiazem; Dose-Response Relationship, Drug; Heart; Male; Methylation; Methyltransferases; Mitochondria, Heart; Myocardium; Organ Culture Techniques; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Sarcolemma; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Verapamil | 2001 |
Diethanolamine induces hepatic choline deficiency in mice.
Topics: Administration, Cutaneous; Animals; Betaine; Carcinogens; Choline Deficiency; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Ethanolamines; Glycerylphosphorylcholine; Liver; Male; Mice; Mice, Inbred C57BL; No-Observed-Adverse-Effect Level; Phosphatidylcholines; Phosphorylcholine; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity | 2002 |
[Staged treatment of patients with severe hepatic alcoholic affection].
Topics: Alcohol-Induced Disorders, Nervous System; Ascitic Fluid; Hemorrhage; Hepatitis, Alcoholic; Humans; Jaundice; Liver Cirrhosis, Alcoholic; Male; Military Medicine; Phosphatidylcholines; Prognosis; Protective Agents; Russia; S-Adenosylmethionine; Silymarin; Vitamin B Complex | 2002 |
Increased response of liver microsomal delta 6-desaturase activity to dietary methionine in rats.
Topics: Animals; Arachidonic Acid; Caseins; Dietary Proteins; Dietary Supplements; Linoleic Acid; Methionine; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Wistar; S-Adenosylmethionine; Stearoyl-CoA Desaturase | 2003 |
The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro.
Topics: Biochemical Phenomena; Biochemistry; Catalysis; Gene Deletion; In Vitro Techniques; Methylation; Methyltransferases; Models, Biological; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; S-Adenosylmethionine; Saccharomyces cerevisiae; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Time Factors | 2004 |
In vivo evidence for the specificity of Plasmodium falciparum phosphoethanolamine methyltransferase and its coupling to the Kennedy pathway.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biochemical Phenomena; Biochemistry; Blotting, Western; Choline; Codon; Ethanolamines; Genetic Complementation Test; Genotype; Methyltransferases; Models, Biological; Molecular Sequence Data; Mutation; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Plasmodium falciparum; Protein Binding; S-Adenosylmethionine; Saccharomyces cerevisiae; Substrate Specificity; Temperature | 2005 |
Phosphatidylcholine and lysophosphatidylcholine excretion is increased in children with cystic fibrosis and is associated with plasma homocysteine, S-adenosylhomocysteine, and S-adenosylmethionine.
Topics: Case-Control Studies; Child; Choline Deficiency; Cross-Sectional Studies; Cystic Fibrosis; Diet Records; Dietary Fats; Feces; Female; Homocysteine; Humans; Intestinal Absorption; Lysophosphatidylcholines; Male; Phosphatidylcholines; S-Adenosylhomocysteine; S-Adenosylmethionine | 2005 |
The role of phospholipid methylation in 1-methyl-4-phenyl-pyridinium ion (MPP+)-induced neurotoxicity in PC12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Dopamine; Lysophosphatidylcholines; Methylation; MPTP Poisoning; PC12 Cells; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipids; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2005 |
Is it time to reevaluate methyl balance in humans?
Topics: Animals; Creatine; Creatinine; Diet; Humans; Methylation; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylmethionine | 2006 |
DLPC and SAMe combined prevent leptin-stimulated TIMP-1 production in LX-2 human hepatic stellate cells by inhibiting HO-mediated signal transduction.
Topics: Cell Line; Drug Antagonism; Drug Combinations; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Kupffer Cells; Leptin; p38 Mitogen-Activated Protein Kinases; Phosphatidylcholines; Phosphorylation; Protease Inhibitors; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1 | 2006 |
DLPC and SAMe prevent alpha1(I) collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione.
Topics: Catalase; Cell Line; Collagen Type I; Glutathione; Hepatocytes; Humans; Hydrogen Peroxide; Leptin; Mitogen-Activated Protein Kinases; Phosphatidylcholines; Phosphorylation; Protein Kinase Inhibitors; RNA, Messenger; S-Adenosylmethionine; Up-Regulation; Vitamin K 3 | 2006 |
Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway.
Topics: Animals; Betaine; Diet; Ethanol; Fatty Liver, Alcoholic; Lipotropic Agents; Liver; Male; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Triglycerides | 2007 |
Methyl balance and transmethylation fluxes in humans.
Topics: Animals; Betaine; Creatine; Diet; Guanidinoacetate N-Methyltransferase; Humans; Kinetics; Liver; Methylation; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine | 2007 |
Hypermethylation of Fads2 and altered hepatic fatty acid and phospholipid metabolism in mice with hyperhomocysteinemia.
Topics: Animals; Cystathionine beta-Synthase; DNA Methylation; Fatty Acids; Gene Silencing; Heterozygote; Hyperhomocysteinemia; Linoleoyl-CoA Desaturase; Lipid Metabolism; Liver; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Promoter Regions, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Biochemical and genetic analysis of the phosphoethanolamine methyltransferase of the human malaria parasite Plasmodium falciparum.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Catalysis; Ethanolamines; Genetic Complementation Test; Humans; Malaria, Falciparum; Methylation; Methyltransferases; Mutation, Missense; Phosphatidylcholines; Plasmodium falciparum; Protozoan Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae | 2008 |
Biochemical disorders associated with antiproliferative effect of dehydroepiandrosterone in hepatoma cells as revealed by LC-based metabolomics.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; Chromatography, Liquid; Dehydroepiandrosterone; Glucosephosphate Dehydrogenase; Humans; Liver Neoplasms; Metabolome; Methionine Adenosyltransferase; Mitochondria; Oxidative Stress; Phosphatidylcholines; Phosphorylcholine; S-Adenosylmethionine | 2011 |
A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Line, Tumor; Endoplasmic Reticulum; Humans; Lipogenesis; Mice; Models, Animal; Phosphatidylcholines; RNA Interference; S-Adenosylmethionine; Sterol Regulatory Element Binding Protein 1; Transcription Factors | 2011 |
Phospholipase D activation mediates cobalamin-induced downregulation of Multidrug Resistance-1 gene and increase in sensitivity to vinblastine in HepG2 cells.
Topics: 1-Butanol; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bezafibrate; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Activators; Gene Expression; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Oleic Acid; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phospholipase D; S-Adenosylmethionine; Vinblastine; Vitamin B 12 | 2013 |
Methyl group balance in brain and liver: role of choline on increased S-adenosyl methionine (SAM) demand by chronic arsenic exposure.
Topics: Animals; Arsenic; Arsenic Poisoning; Brain; Choline; Female; Immunohistochemistry; Liver; Male; Methylation; Phosphatidylcholines; Pregnancy; Rats; Rats, Wistar; S-Adenosylmethionine; Thiobarbituric Acid Reactive Substances; Triglycerides | 2012 |
Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis.
Topics: Animals; Disease Models, Animal; Fatty Liver; Female; Glycine N-Methyltransferase; Homeostasis; Lipid Metabolism; Liver; Male; Membrane Proteins; Mice; Mice, Knockout; Perilipin-2; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine; Triglycerides | 2013 |
Multiple inputs control sulfur-containing amino acid synthesis in Saccharomyces cerevisiae.
Topics: Basic-Leucine Zipper Transcription Factors; Cysteine; F-Box Proteins; Gene Expression Regulation, Fungal; Green Fluorescent Proteins; Methionine; Methionine Adenosyltransferase; Methylation; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ubiquitin-Protein Ligase Complexes; Ubiquitination | 2014 |
[Hepatoprotectors in treatment of alcoholic liver disease].
Topics: Animals; Biological Products; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Male; Phosphatidylcholines; Rats; Rats, Wistar; S-Adenosylmethionine; Treatment Outcome | 2013 |
s-Adenosylmethionine Levels Govern Innate Immunity through Distinct Methylation-Dependent Pathways.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Immunity, Innate; Liver; Methionine Adenosyltransferase; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidylcholines; Promoter Regions, Genetic; Pseudomonas aeruginosa; RNA Interference; RNA, Small Interfering; S-Adenosylmethionine; Signal Transduction | 2015 |
[Pharmacoeconomic Analysis of the Use of Hepatoprotectors in Management of Drug-Associated Liver Injury Due to Hodgkin's Lymphoma Chemotherapy].
Topics: Antineoplastic Agents; Case-Control Studies; Chemical and Drug Induced Liver Injury; Cost-Benefit Analysis; Disease Management; Hodgkin Disease; Humans; Liver; Phosphatidylcholines; Protective Agents; Retrospective Studies; S-Adenosylmethionine; Succinates; Treatment Outcome | 2015 |
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors | 2016 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
Petit-High Pressure Carbon Dioxide stress increases synthesis of S-Adenosylmethionine and phosphatidylcholine in yeast Saccharomyces cerevisiae.
Topics: Biocatalysis; Carbon Dioxide; Cluster Analysis; Metabolomics; Microscopy, Electron, Scanning; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylcholines; Pressure; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2017 |
A Metabolic Function for Phospholipid and Histone Methylation.
Topics: Cysteine; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Histones; Lysine; Methylation; Mutation; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Protein Phosphatase 2; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Transcription, Genetic | 2017 |
AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle.
Topics: Animals; Carbon Cycle; Fibroblast Growth Factors; Glycine N-Methyltransferase; Humans; Liver; Male; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Protein Binding; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; S-Adenosylmethionine | 2018 |
Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice.
Topics: Animals; Basidiomycota; Diet, High-Fat; Fructose; Fungal Polysaccharides; Hypoglycemic Agents; Insulin Resistance; Intestinal Mucosa; Intestines; Liver; Male; Mice; Mice, Inbred C57BL; Microbiota; Obesity; Phosphatidylcholines; S-Adenosylmethionine; Sucrose; Vitamin B 12 | 2018 |
GlmS mediated knock-down of a phospholipase expedite alternate pathway to generate phosphocholine required for phosphatidylcholine synthesis in Plasmodium falciparum.
Topics: Carboxy-Lyases; Choline; Erythrocytes; Gene Expression Regulation; Gene Knockdown Techniques; Genes, Reporter; Green Fluorescent Proteins; Homeostasis; Humans; Life Cycle Stages; Lipid Metabolism; Lysophosphatidylcholines; Lysophospholipase; Methyltransferases; Phosphatidylcholines; Phosphorylcholine; Plasmodium falciparum; Protozoan Proteins; S-Adenosylmethionine; Serine | 2021 |
Reciprocal regulation of phosphatidylcholine synthesis and H3K36 methylation programs metabolic adaptation.
Topics: Histones; Methylation; Phosphatidylcholines; Phospholipids; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2022 |
Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups.
Topics: Animals; Choline; Glycerylphosphorylcholine; Liver; Lysophospholipase; Methionine; Mice; Phosphatidylcholines; Racemethionine; S-Adenosylmethionine; Triglycerides | 2023 |