phosphatidylcholines has been researched along with n-formylmethionine leucyl-phenylalanine in 32 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (n-formylmethionine leucyl-phenylalanine) | Trials (n-formylmethionine leucyl-phenylalanine) | Recent Studies (post-2010) (n-formylmethionine leucyl-phenylalanine) |
|---|---|---|---|---|---|
| 32,204 | 443 | 5,593 | 6,716 | 53 | 356 |
| Protein | Taxonomy | phosphatidylcholines (IC50) | n-formylmethionine leucyl-phenylalanine (IC50) |
|---|---|---|---|
| fMet-Leu-Phe receptor | Homo sapiens (human) | 0.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (21.88) | 18.7374 |
| 1990's | 21 (65.63) | 18.2507 |
| 2000's | 2 (6.25) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernardo, J; Casavant, D; Diamond, RD; Haugland, RP; Herscovitz, H; Meshulam, T; Roman, R; Simons, ER; Strohmeier, GS | 1 |
| Baggiolini, M; Chap, H; Gélas, P; Record, M; Von Tscharner, V | 1 |
| Mohsenin, V; Yoshida, K | 1 |
| Borgeat, P; Bourgoin, S; Poubelle, PE | 1 |
| Agwu, DE; McCall, CE; McPhail, LC | 1 |
| Billah, MM; Eckel, S; Egan, RW; Mullmann, TJ; Pai, JK; Siegel, MI | 1 |
| Haines, KA; Weissmann, G | 1 |
| Blake, M; Haines, KA; Reibman, J; Tang, XY; Weissmann, G | 1 |
| McIntyre, TM; Prescott, SM; Reinhold, SL; Zimmerman, GA | 1 |
| Chap, H; Gelas, P; Record, M; Ribbes, G; Terce, F | 1 |
| Billah, MM; Eckel, S; Egan, RW; Mullmann, TJ; Siegel, MI | 1 |
| Broekman, MJ; Korchak, HM; Marcus, AJ; Weissmann, G; Wynkoop, EM | 1 |
| Freer, RJ; Hoyle, PC | 1 |
| Lees, CJ; Lewis, JC; Love, SH; McCall, CE; Miller, CH; O'Flaherty, JT; Wykle, RL | 1 |
| Pike, MC; Snyderman, R | 1 |
| Chap, H; Planat, V; Record, M; Ribbes, G; Tercé, F; Tronchère, H | 1 |
| Du, B; He, S; Ho, JL; Rothman, R; Zhu, B | 1 |
| Hidi, R; Touqui, L; Vargaftig, BB | 1 |
| Daniel, LW; Nixon, AB; Strum, JC; Wykle, RL | 1 |
| Mohsenin, V; Ortmeyer, J | 1 |
| Gomez-Cambronero, J | 1 |
| Bellido, ML; Lucas, M; Pedrera, C; Sänchez-Margalet, V | 1 |
| Pinckard, RN; Prihoda, TJ | 1 |
| Cockcroft, S; Collison, KS; Cunningham, E; Morgan, CP; Whatmore, J; Willison, KR | 1 |
| Exton, JH; Guillemain, I | 1 |
| Brown, LA; Guidot, DM; Holguin, F; Moss, I | 1 |
| Bambara, LM; Bellavite, P; Biasi, D; Caramaschi, P; Carletto, A; Corrocher, R; Galvani, S; Guarini, P | 1 |
| Curstedt, T; Eklund, A; Lundahl, J; Zetterberg, G | 1 |
| Tou, J; Urbizo, C | 1 |
| Clay, K; Dinauer, M; Hiran, T; Johnson, C; Travers, J | 1 |
| Al-Suwayeh, SA; Fang, CL; Fang, JY; Hwang, TL; Yang, LJ | 1 |
| Funakoshi, Y; Hongu, T; Kanaho, Y; Sato, T | 1 |
1 trial(s) available for phosphatidylcholines and n-formylmethionine leucyl-phenylalanine
| Article | Year |
|---|---|
Effects of dietary fish oil and soy phosphatidylcholine on neutrophil fatty acid composition, superoxide release, and adhesion.
Topics: Adolescent; Adult; Arachidonic Acid; Cell Adhesion; Cod Liver Oil; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Omega-3; Female; Glycine max; Humans; In Vitro Techniques; Linoleic Acid; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Respiratory Burst; Superoxides | 1998 |
31 other study(ies) available for phosphatidylcholines and n-formylmethionine leucyl-phenylalanine
| Article | Year |
|---|---|
Flow cytometric kinetic measurements of neutrophil phospholipase A activation.
Topics: Boron Compounds; Calcium; Cells, Cultured; Enzyme Activation; Flow Cytometry; Fluorescent Dyes; Humans; Kinetics; Liposomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Phospholipases A | 1992 |
Human neutrophil phospholipase D activation by N-formylmethionyl-leucylphenylalanine reveals a two-step process for the control of phosphatidylcholine breakdown and oxidative burst.
Topics: Androstadienes; Calcium; Coumarins; Cytochalasin B; Enzyme Activation; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Respiratory Burst; Signal Transduction; Time Factors | 1992 |
Unsaturated phosphatidylcholines inhibit superoxide production in human neutrophils.
Topics: Analysis of Variance; Cell Fractionation; Diglycerides; Enzyme Activation; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) primes human neutrophils for enhanced phosphatidylcholine breakdown by phospholipase D.
Topics: Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Phospholipase D; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Up-Regulation | 1991 |
Regulation of phospholipase D-induced hydrolysis of choline-containing phosphoglycerides by cyclic AMP in human neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; Cyclic AMP; Dinoprostone; Humans; Hydrolysis; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1991 |
The eicosanoid lipid precursors diacyl-glycerol and phosphatidic acid are formed by phospholipase D in neutrophils.
Topics: Diglycerides; Eicosanoids; Ethanol; Humans; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Propranolol | 1991 |
Protein I of N. gonorrhoeae shows that phosphatidate from phosphatidylcholine via phospholipase C is an intracellular messenger in neutrophil activation by chemoattractants.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Bacterial Outer Membrane Proteins; Diglycerides; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neisseria gonorrhoeae; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipids; Porins; Receptors, Fc; Second Messenger Systems; Type C Phospholipases | 1991 |
Effects of protein I of Neisseria gonorrhoeae on neutrophil activation: generation of diacylglycerol from phosphatidylcholine via a specific phospholipase C is associated with exocytosis.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Bacterial Outer Membrane Proteins; Cells, Cultured; Diglycerides; Enzyme Activation; Ethanol; Exocytosis; Humans; Kinetics; Lymphocyte Activation; N-Formylmethionine Leucyl-Phenylalanine; Neisseria gonorrhoeae; Neutrophils; Phosphatidylcholines; Phospholipids; Porins; Propranolol; Protein Kinase C; Type C Phospholipases | 1991 |
Phospholipid remodeling in human neutrophils. Parallel activation of a deacylation/reacylation cycle and platelet-activating factor synthesis.
Topics: Acylation; Calcimycin; Fatty Acids, Nonesterified; Glycerol; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipids; Platelet Activating Factor | 1989 |
Differential activation by fMet-Leu-Phe and phorbol ester of a plasma membrane phosphatidylcholine-specific phospholipase D in human neutrophil.
Topics: Cell Membrane; Cytochalasin B; Enzyme Activation; Humans; Hydrolysis; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Phospholipase D; Phospholipases; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Phosphatidylcholine hydrolysis by phospholipase D determines phosphatidate and diglyceride levels in chemotactic peptide-stimulated human neutrophils. Involvement of phosphatidate phosphohydrolase in signal transduction.
Topics: Diglycerides; Enzyme Activation; Glycerides; Humans; Hydrolysis; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidate Phosphatase; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Phospholipases; Signal Transduction; Substrate Specificity; Type C Phospholipases | 1989 |
Phospholipid metabolism in human neutrophils activated by N-formyl-methionyl-leucyl-phenylalanine. Degranulation is not required for release of arachidonic acid: studies with neutrophils and neutrophil-derived cytoplasts.
Topics: Arachidonic Acids; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids | 1986 |
Isolation and reconstitution of the N-formylpeptide receptor from HL-60 derived neutrophils.
Topics: Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Membranes, Artificial; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Protein Binding; Receptors, Cell Surface; Receptors, Formyl Peptide; Solubility | 1984 |
Selective desensitization of neutrophils: further studies with 1-O-alkyl-sn-glycero-3-phosphocholine analogues.
Topics: Animals; Calcium; Cattle; Cell Aggregation; Cytoplasmic Granules; Humans; Magnesium; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phosphatidylcholines | 1981 |
Alterations of new methylated phospholipid synthesis in the plasma membranes of macrophages exposed to chemoattractants.
Topics: Animals; Cell Membrane; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5; Guinea Pigs; Macrophages; Membrane Lipids; Methylation; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Phosphatidylcholines; Phosphatidylethanolamines | 1981 |
Phosphatidylcholine turnover in activated human neutrophils. Agonist-induced cytidylyltransferase translocation is subsequent to phospholipase D activation.
Topics: Biological Transport; Catalysis; Choline; Choline-Phosphate Cytidylyltransferase; Cytochalasin B; Enzyme Activation; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Nucleotidyltransferases; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1995 |
Interleukin 4 receptor signaling in human monocytes and U937 cells involves the activation of a phosphatidylcholine-specific phospholipase C: a comparison with chemotactic peptide, FMLP, phospholipase D, and sphingomyelinase.
Topics: Arachidonic Acid; Calcium; Diglycerides; Enzyme Activation; Humans; Interleukin-4; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phospholipase D; Receptors, Interleukin; Receptors, Interleukin-4; Sphingomyelin Phosphodiesterase; Type C Phospholipases | 1994 |
Increased synthesis and secretion of a 14-kDa phospholipase A2 by guinea pig alveolar macrophages. Dissociation from arachidonic acid liberation and modulation by dexamethasone.
Topics: Animals; Arachidonic Acid; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Guinea Pigs; Hydrogen-Ion Concentration; Leukotriene B4; Macrophages, Alveolar; Male; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Thromboxane B2 | 1993 |
Evaluation of phospholipase C and D activity in stimulated human neutrophils using a phosphono analog of choline phosphoglyceride.
Topics: Calcimycin; Diglycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Tritium; Type C Phospholipases | 1993 |
Glucose suppresses superoxide generation in normal neutrophils: interference in phospholipase D activation.
Topics: Calcium; Enzyme Activation; Glucose; Humans; Hydrolysis; Intracellular Membranes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Phosphatidylcholines; Phospholipase D; Receptors, Formyl Peptide; Receptors, Immunologic; Reference Values; Superoxides | 1993 |
Immunoprecipitation of a phospholipase D activity with antiphosphotyrosine antibodies.
Topics: Antibodies, Monoclonal; Carbon Radioisotopes; Glycerophospholipids; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phosphotyrosine; Precipitin Tests; Stimulation, Chemical; Substrate Specificity | 1995 |
A chemiluminescence method to analyze phosphatidylcholine-phospholipase activity in plasma membrane preparations and in intact cells.
Topics: Animals; Blood Donors; Calcimycin; Cell Membrane; Enzyme Activation; Humans; Hydrolysis; Leukocytes; Linear Models; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phospholipase D; Rats; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1995 |
Alkyl-PAF and acyl-PAF human neutrophil priming for enhanced fMLP- and rC5a-induced superoxide anion production.
Topics: Adrenergic beta-Antagonists; Amino Acid Sequence; Anions; Azepines; Complement C5a; Drug Synergism; Female; Humans; Male; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphatidylcholines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Recombinant Proteins; Superoxides; Triazoles | 1996 |
ADP-ribosylation factor 1-regulated phospholipase D activity is localized at the plasma membrane and intracellular organelles in HL60 cells.
Topics: 1-Phosphatidylinositol 4-Kinase; Acetates; ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Biomarkers; Cell Fractionation; Cell Membrane; Cells, Cultured; Centrifugation, Density Gradient; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Glycerophospholipids; Golgi Apparatus; GTP-Binding Proteins; Guanosine Triphosphate; N-Formylmethionine Leucyl-Phenylalanine; Neomycin; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Phospholipids; Phosphotransferases (Alcohol Group Acceptor) | 1996 |
Effects of brefeldin A on phosphatidylcholine phospholipase D and inositolphospholipid metabolism in HL-60 cells.
Topics: Adenosine Triphosphate; ADP-Ribosylation Factors; Brefeldin A; Cyclopentanes; Enzyme Activation; Enzyme Inhibitors; Galactosyltransferases; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotoxin-mediated acute edematous lung injury in rats.
Topics: Acetylcysteine; Acute Disease; Alcohol Drinking; Animals; Bacterial Toxins; Bronchoalveolar Lavage Fluid; Causality; Cell Survival; Chemotherapy, Cancer, Regional Perfusion; Endotoxins; Ethanol; Glutathione; Homeostasis; Lung; Lung Injury; Male; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1998 |
Lysophosphatidylcholine abrogates the CR1 preserving effect of surfactant on quartz-exposed human granulocytes.
Topics: Granulocytes; Hot Temperature; Humans; Lysophosphatidylcholines; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Pulmonary Surfactants; Quartz; Receptors, Complement 3b | 1999 |
Resveratrol inhibits the formation of phosphatidic acid and diglyceride in chemotactic peptide- or phorbol ester-stimulated human neutrophils.
Topics: Choline; Chromatography, Thin Layer; Diglycerides; Drug Interactions; Ethanol; Ethanolamine; Glycerophosphates; Glycerophospholipids; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Evidence for the involvement of the NADPH oxidase enzyme complex in the optimal accumulation of Platelet-activating factor in the human cell line PLB-985.
Topics: Calcimycin; Calcium; Cell Line; Gas Chromatography-Mass Spectrometry; Glycerylphosphorylcholine; Humans; Ionophores; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphatidylcholines; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Activated human neutrophil response to perfluorocarbon nanobubbles: oxygen-dependent and -independent cytotoxic responses.
Topics: Adult; Cell Survival; Fluorocarbons; Humans; L-Lactate Dehydrogenase; N-Formylmethionine Leucyl-Phenylalanine; Nanoparticles; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Phosphatidylcholines; Reactive Oxygen Species; Superoxides; Young Adult | 2011 |
Molecular mechanisms of fMLP-induced superoxide generation and degranulation in mouse neutrophils.
Topics: Animals; Calcium; Calcium Ionophores; Cell Degranulation; Diglycerides; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Signal Transduction; Superoxides | 2013 |