Page last updated: 2024-09-05

phosphatidylcholines and methylprednisolone

phosphatidylcholines has been researched along with methylprednisolone in 13 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(methylprednisolone)
Trials
(methylprednisolone)
Recent Studies (post-2010) (methylprednisolone)
32,2044435,59320,2472,6025,317

Protein Interaction Comparison

ProteinTaxonomyphosphatidylcholines (IC50)methylprednisolone (IC50)
Glucocorticoid receptorHomo sapiens (human)0.011
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.011
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.011
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.011
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.011

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19908 (61.54)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Obladen, M1
Block, MF; Crosby, WM; Kling, OR1
Felbo, M; Fonseca, G; Hancke, S; Jørgensen, PI; Larsen, JF; Vang, N; Verder, H1
Fortmeyer, HP; Gerner, R; Halberstadt, E1
Gerner, R; Halberstadt, E1
Eckert, H; Gerner, R; Halberstadt, E; Schulz, J; Wernicke, K1
Ichikawa, I; Kikkawa, Y1
Benfield, JR; Drews, JA; Tierney, DF1
Jusko, WJ; Mishina, EV; Pyszczynski, NA; Straubinger, RM1
Hiyama, K; Ishioka, S; Maeda, A; Tamagawa, K; Taooka, Y; Yamakido, M1
Chikawa, T; Fukuzawa, K; Hamada, Y; Ikata, T; Katoh, S; Kogure, K1
Kawashima, T; Kuroda, T; Matsuzawa, Y; Nishide, T; Shirai, K; Wakabayashi, T1
Beers, MF; Griese, M; Hartl, D; Hector, A; Kern, S; Liebisch, G; Mulugeta, S; Schmitz, G; Sparr, C; Thurm, T; Woischnik, M1

Trials

1 trial(s) available for phosphatidylcholines and methylprednisolone

ArticleYear
Antenatal glucocorticoid therapy for the prevention of respiratory distress syndrome in the premature infant.
    Obstetrics and gynecology, 1977, Volume: 50, Issue:2

    Topics: Amniotic Fluid; Betamethasone; Clinical Trials as Topic; Double-Blind Method; Female; Fetal Death; Glucocorticoids; Humans; Infant Mortality; Infant, Newborn; Injections, Intramuscular; Lung; Maternal-Fetal Exchange; Methylprednisolone; Oklahoma; Phosphatidylcholines; Pregnancy; Prenatal Care; Respiratory Distress Syndrome, Newborn; Sodium Chloride; Sphingomyelins; Time Factors

1977

Other Studies

12 other study(ies) available for phosphatidylcholines and methylprednisolone

ArticleYear
Factors influencing surfactant composition in the newborn infant.
    European journal of pediatrics, 1978, Jul-03, Volume: 128, Issue:3

    Topics: alpha 1-Antitrypsin Deficiency; Female; Glucocorticoids; Hepatitis; Humans; Hypothyroidism; Infant, Newborn; Infant, Premature; Maternal-Fetal Exchange; Methylprednisolone; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Pregnancy; Pregnancy Complications; Pregnancy in Diabetics; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Substance-Related Disorders; Surface Tension; Uterine Hemorrhage

1978
Lecithin-spingomyelin ratio in amniotic fluid for determination of the optimal time of termination of pregnancy.
    Danish medical bulletin, 1978, Volume: 25, Issue:5

    Topics: Amniotic Fluid; Cesarean Section; Female; Gestational Age; Humans; Infant, Newborn; Labor, Induced; Methylprednisolone; Phosphatidylcholines; Pregnancy; Pregnancy Complications; Respiratory Distress Syndrome, Newborn; Sphingomyelins

1978
[In vivo and in vitro investigations of the effect of decortilen (16-methylenprednisolone) on lecithin synthesis in the fetal lung (author's transl)].
    Zeitschrift fur Geburtshilfe und Perinatologie, 1976, Volume: 180, Issue:3

    Topics: Animals; Choline; Female; Humans; Hyaline Membrane Disease; In Vitro Techniques; Infant, Newborn; Lung; Methylation; Methylprednisolone; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Rats

1976
[Experimental investigations in regard to the optimal stimulation of lecithin synthesis in the fetal lung via glucocorticoids (author's transl)].
    Zeitschrift fur Geburtshilfe und Perinatologie, 1976, Volume: 180, Issue:3

    Topics: Animals; Choline; Dexamethasone; Dose-Response Relationship, Drug; Female; Glucocorticoids; Hydrocortisone; In Vitro Techniques; Lung; Methylprednisolone; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Rats

1976
[Influence of corticoids on fetal lung maturity].
    Archiv fur Gynakologie, 1975, Nov-18, Volume: 219, Issue:1-4

    Topics: Adrenal Cortex Hormones; Amniotic Fluid; Female; Fetus; Humans; Hyaline Membrane Disease; Infant, Newborn; Lung; Methylprednisolone; Phosphatidylcholines; Pregnancy

1975
Alteration in phospholipid content of lung of adult rats treated with methylprednisolone of high doses.
    Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:11

    Topics: Animals; Body Weight; Cardiolipins; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Lung; Macrophages; Male; Methylprednisolone; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Sphingomyelins

1985
Effect of immunosuppression and lung transplantation upon surfactant.
    Surgery, 1974, Volume: 76, Issue:1

    Topics: Animals; Azathioprine; Carbon Radioisotopes; Chromatography, Gas; Chromatography, Thin Layer; DNA; Dogs; Graft Rejection; Immunosuppressive Agents; Lung; Lung Transplantation; Methylprednisolone; Palmitic Acids; Phosphatidylcholines; Pulmonary Surfactants; Scintillation Counting; Transplantation, Autologous; Transplantation, Homologous

1974
Enhancement of tissue delivery and receptor occupancy of methylprednisolone in rats by a liposomal formulation.
    Pharmaceutical research, 1993, Volume: 10, Issue:10

    Topics: Animals; Bone Marrow; Cytosol; Drug Carriers; Liposomes; Liver; Male; Methylprednisolone; Phosphatidylcholines; Phosphatidylglycerols; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Spleen; Thymus Gland; Tissue Distribution

1993
Inhibitory effects of a lecithinized superoxide dismutase on bleomycin-induced pulmonary fibrosis in mice.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:4 Pt 1

    Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Hydroxyproline; Interleukin-1; Lung; Male; Methylprednisolone; Mice; Mice, Inbred ICR; Phosphatidylcholines; Platelet-Derived Growth Factor; Pulmonary Fibrosis; Superoxide Dismutase

2000
Preventive effects of lecithinized superoxide dismutase and methylprednisolone on spinal cord injury in rats: transcriptional regulation of inflammatory and neurotrophic genes.
    Journal of neurotrauma, 2001, Volume: 18, Issue:1

    Topics: Animals; Gene Expression Regulation; Glycerol-3-Phosphate Dehydrogenase (NAD+); Glycerolphosphate Dehydrogenase; Intercellular Adhesion Molecule-1; Interleukin-1; Male; Methylprednisolone; Movement Disorders; Myelitis; Nerve Growth Factors; Neurotrophin 3; Nitric Oxide Synthase; Phosphatidylcholines; Rats; Rats, Wistar; Recovery of Function; RNA, Messenger; Spinal Cord Injuries; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Transcription, Genetic

2001
Lecithinized superoxide dismutase treatment improves steroid-refractory interstitial pneumonia.
    Respirology (Carlton, Vic.), 2010, Volume: 15, Issue:8

    Topics: Adrenal Cortex Hormones; Cyclosporine; Dermatomyositis; Exercise Tolerance; Humans; Immunosuppressive Agents; Lung Diseases, Interstitial; Male; Methylprednisolone; Middle Aged; Mucin-1; Phosphatidylcholines; Prednisolone; Pulmonary Fibrosis; Radiography; Respiratory Function Tests; Superoxide Dismutase; Tacrolimus; Treatment Outcome

2010
A non-BRICHOS surfactant protein c mutation disrupts epithelial cell function and intercellular signaling.
    BMC cell biology, 2010, Nov-20, Volume: 11

    Topics: Amino Acid Substitution; Animals; Azathioprine; Bronchoalveolar Lavage Fluid; Calnexin; Calreticulin; CD4-Positive T-Lymphocytes; Cell Line; Cyclophosphamide; Epithelial Cells; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Hydroxychloroquine; Lung Diseases, Interstitial; Methylprednisolone; Mice; Mutation; Phosphatidylcholines; Pulmonary Surfactant-Associated Protein C; Receptors, CCR2; Receptors, Interleukin-8A; Signal Transduction

2010