phosphatidylcholines has been researched along with lovastatin in 16 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (lovastatin) | Trials (lovastatin) | Recent Studies (post-2010) (lovastatin) |
|---|---|---|---|---|---|
| 32,204 | 443 | 5,593 | 4,828 | 698 | 873 |
| Protein | Taxonomy | phosphatidylcholines (IC50) | lovastatin (IC50) |
|---|---|---|---|
| Chain A, Antigen Cd11a (p180) | Homo sapiens (human) | 2.4 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.0261 | |
| Integrin beta-2 | Homo sapiens (human) | 3.09 | |
| Intercellular adhesion molecule 1 | Homo sapiens (human) | 3.78 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 8.753 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 10 | |
| Neutrophil elastase | Homo sapiens (human) | 0.027 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 0.02 | |
| Integrin alpha-L | Homo sapiens (human) | 3.09 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 8.753 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.02 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0529 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andreini, JP; Duane, WC; Evans, CD; Gebhard, RL; Prigge, W; Stone, BG | 1 |
| Gebhard, RL; Prigge, WF | 1 |
| Escousse, A; Goudonnet, H; Mercenne, F; Mounie, J; Truchot, RC | 1 |
| Adams, SE; Bishop, EJ; Melnykovych, G | 1 |
| Edwards, PA; Fogelman, AM; Lan, SF | 1 |
| Atreyee, B; John, W; Jyotirmoy, N; Linscheer, WG; Sándor, N; Uma, KM | 1 |
| Aviram, M; Brook, JG; Cogan, U; Hochgraf, E; Levy, Y | 1 |
| Bondarenko, BB; Gurevich, VS; Kasennova, NI; Le Van Thach, TD; Mikhailova, IA | 1 |
| Kronqvist, R; Leppimäki, P; Slotte, JP | 1 |
| Göritz, C; Mauch, DH; Müller, EC; Nägler, K; Otto, A; Pfrieger, FW; Schumacher, S | 1 |
| Ebetino, FH; Edwards, CM; Hulley, PA; Roelofs, AJ; Rogers, MJ; Russell, RG | 1 |
| Gehrig, K; Lagace, TA; Ridgway, ND | 1 |
| Detrick, MS; Dvoracek, LA; Francis, AD; Kacmarik, KL; Kreisberg, JI; Kreisberg, R; Lee, HM; McKinney, J; Primerano, DA; Santanam, N; Schmid, G | 1 |
| Chen, CC; Fang, JY; Huang, ZR; Tsai, TH | 1 |
| Fujino, H; Kawashima, T; Makiyama, T; Matsuzawa, Y; Murayama, T; Yamaura, E; Yamazaki, R | 1 |
| Aganov, A; Galiullina, LF; Huster, D; Klochkov, V; Scheidt, HA | 1 |
16 other study(ies) available for phosphatidylcholines and lovastatin
| Article | Year |
|---|---|
Thyroid hormone differentially augments biliary sterol secretion in the rat. I. The isolated-perfused liver model.
Topics: Animals; Bile; Bile Acids and Salts; Cholesterol; Drug Combinations; In Vitro Techniques; Liver; Lovastatin; Male; Perfusion; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Thyroxine; Triiodothyronine | 1992 |
Thyroid hormone differentially augments biliary sterol secretion in the rat. II. The chronic bile fistula model.
Topics: Animals; Bile; Biliary Fistula; Cholesterol; Lovastatin; Male; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Triiodothyronine | 1992 |
Effects of simvastatin, a lipoprotein-lowering drug, on the hepatic enzymes involved in drug metabolism in the Wistar rat.
Topics: Animals; Body Weight; Enzyme Induction; Epoxide Hydrolases; Fatty Acids; Glycerolphosphate Dehydrogenase; Hypolipidemic Agents; In Vitro Techniques; Liver; Lovastatin; Male; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Phosphatidylcholines; Rats; Rats, Inbred Strains; Simvastatin; Subcellular Fractions | 1991 |
Elevation of alkaline phosphatase by retinol in bovine endothelial cells and its possible relationship to lipid biosynthesis.
Topics: Alkaline Phosphatase; Animals; Aorta; Cattle; Cells, Cultured; Cholesterol; Dexamethasone; Drug Synergism; Endothelium; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Lipids; Lovastatin; Naphthalenes; Phosphatidylcholines; Tunicamycin; Vitamin A | 1986 |
High density lipoproteins and lecithin dispersions increase the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase by increasing the rate of synthesis and decreasing the rate of degradation of the enzyme.
Topics: Animals; Humans; Hydroxymethylglutaryl CoA Reductases; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Liposomes; Lovastatin; Molecular Weight; Naphthalenes; Phosphatidylcholines; Rats | 1984 |
Lovastatin induces synthesis of cholesterol, which acts as a secretagogue of biliary phospholipids in rats.
Topics: Animals; Bile; Bile Acids and Salts; Cholesterol; Choline; Choline-Phosphate Cytidylyltransferase; Cytosol; Light; Lipids; Lovastatin; Male; Micelles; Microsomes, Liver; Nucleotidyltransferases; Phosphatidylcholines; Phospholipids; Rats; Rats, Wistar; Scattering, Radiation | 1995 |
Lovastatin decreases plasma and platelet cholesterol levels and normalizes elevated platelet fluidity and aggregation in hypercholesterolemic patients.
Topics: Administration, Oral; Adult; Blood Platelets; Cholesterol; Female; Fluorescence Polarization; Humans; Hypercholesterolemia; Lovastatin; Male; Membrane Fluidity; Middle Aged; Phosphatidylcholines; Phospholipids; Platelet Aggregation; Sphingomyelins | 1994 |
Evidence of combined therapy of dyslipoproteinemia by HMG-CoA reductase inhibitors and "essential" phospholipids.
Topics: Adult; Cholesterol; Coronary Disease; Drug Therapy, Combination; Humans; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Male; Phosphatidylcholines; Platelet Aggregation | 1993 |
The rate of sphingomyelin synthesis de novo is influenced by the level of cholesterol in cultured human skin fibroblasts.
Topics: Acyltransferases; Apolipoprotein A-I; Carbon Radioisotopes; Cells, Cultured; Ceramides; Cholesterol; Cyclodextrins; Cycloserine; Fibroblasts; Humans; Lovastatin; Monensin; Palmitic Acids; Phosphatidylcholines; Phosphatidylglycerols; Serine C-Palmitoyltransferase; Sphingomyelin Phosphodiesterase; Sphingomyelins | 1998 |
CNS synaptogenesis promoted by glia-derived cholesterol.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Cells, Cultured; Cholesterol; Culture Media, Conditioned; Excitatory Postsynaptic Potentials; Lovastatin; Neuroglia; Patch-Clamp Techniques; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Sphingomyelins; Synapses; Synaptic Transmission | 2001 |
Apomine enhances the antitumor effects of lovastatin on myeloma cells by down-regulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Diphosphonates; Down-Regulation; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Multiple Myeloma; Phosphatidylcholines; Protein Prenylation | 2007 |
Oxysterol activation of phosphatidylcholine synthesis involves CTP:phosphocholine cytidylyltransferase alpha translocation to the nuclear envelope.
Topics: Active Transport, Cell Nucleus; Animals; Cell Line; Choline-Phosphate Cytidylyltransferase; Cricetinae; Enzyme Activation; Hydroxycholesterols; Lovastatin; Mice; Nuclear Envelope; Phosphatidylcholines; Rats | 2009 |
Lovastatin inhibits oxidized L-A-phosphatidylcholine B-arachidonoyl-gamma-palmitoyl (ox-PAPC)-stimulated interleukin-8 mRNA and protein synthesis in human aortic endothelial cells by depleting stores of geranylgeranyl pyrophosphate.
Topics: Aorta; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Humans; Interleukin-8; Lovastatin; Phosphatidylcholines; Polyisoprenyl Phosphates; Protein Biosynthesis; RNA, Messenger | 2010 |
Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: physicochemical characterization and pharmacokinetics.
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Biological Availability; Chemical Phenomena; Delayed-Action Preparations; Diglycerides; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Emulsifying Agents; Gastrointestinal Tract; Lipids; Lovastatin; Male; Nanoparticles; Particle Size; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Squalene; Surface Properties; Tissue Distribution | 2010 |
Inhibitory effects of clinical reagents having anti-oxidative activity on transforming growth factor-β1-induced expression of α-smooth muscle actin in human fetal lung fibroblasts.
Topics: Acetylcysteine; Actins; alpha-Tocopherol; Antioxidants; Cell Line; Fetus; Fibroblasts; Humans; Hypolipidemic Agents; Lovastatin; Lung; Phosphatidylcholines; Probucol; Reactive Oxygen Species; Superoxide Dismutase; Transforming Growth Factor beta1 | 2011 |
Interaction of statins with phospholipid bilayers studied by solid-state NMR spectroscopy.
Topics: Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Bilayers; Lovastatin; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phospholipids; Pravastatin; Simvastatin | 2019 |