phosphatidylcholines has been researched along with lidocaine in 25 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (lidocaine) | Trials (lidocaine) | Recent Studies (post-2010) (lidocaine) |
|---|---|---|---|---|---|
| 32,204 | 443 | 5,593 | 26,090 | 5,904 | 5,591 |
| Protein | Taxonomy | phosphatidylcholines (IC50) | lidocaine (IC50) |
|---|---|---|---|
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | 2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (44.00) | 18.7374 |
| 1990's | 8 (32.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hendrickson, HS | 1 |
| Hendrickson, HS; van Dam-Mieras, MC | 1 |
| Clague, AE; McGeary, HM | 1 |
| Inagaki, Y; Mashimo, T; Nishimura, S; Pak, M; Shibata, A; Uchida, I; Yoshiya, I | 1 |
| Funae, Y; Imai, Y; Imaoka, S; Shimada, T | 1 |
| Kokubu, M; Machida, M; Oda, K; Shinya, N | 1 |
| Nettleton, J; Wang, GK | 1 |
| Gallová, J; Ondrias, K; Stolc, S; Szöcsová, H | 1 |
| Haynes, DH; Kirkpatrick, AF | 1 |
| Halsey, MJ; Simmonds, AC | 1 |
| Bressie, S; Jeng, I; Klemm, N; Samson, L | 1 |
| Martonosi, A; Vanderkooi, JM | 1 |
| Cerbón, J; Fernández, MS | 1 |
| Bell, FP; Hubert, EV | 1 |
| Davio, SR; Low, PS | 1 |
| Chu, AJ; Lee, JM | 1 |
| Chiou, JS; Kamaya, H; Krishna, PR; Ueda, I | 1 |
| Ottiger, C; Wunderli-Allenspach, H | 1 |
| Engström, S; Nordén, TP; Nyquist, H | 1 |
| Braga, AA; de Paula, E; Fraceto, LF; Franzoni, L; Pinto, Lde M; Schreier, S; Spisni, A | 1 |
| Mizogami, M; Takakura, K; Tsuchiya, H; Ueno, T | 1 |
| Mizogami, M; Shigemi, K; Tsuchiya, H | 1 |
| Bandeiras, C; Fernandes, A; Luzyanin, K; Saramago, B; Serro, AP | 1 |
| Li, F; Peng, X; Zeng, K; Zhu, X | 1 |
| Abdel-Rehim, M; Duša, F; Holma, P; Holopainen, JM; Rantamäki, AH; Robciuc, A; Ruokonen, SK; Wiedmer, SK | 1 |
25 other study(ies) available for phosphatidylcholines and lidocaine
| Article | Year |
|---|---|
The penetration of local anesthetics into phosphatidylcholine monolayers.
Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Biological Transport; Dibucaine; Kinetics; Lidocaine; Membranes, Artificial; Models, Biological; Permeability; Phosphatidylcholines; Procaine; Structure-Activity Relationship; Tetracaine; Triglycerides | 1976 |
Local anesthetic inhibition of pancreatic phospholipase A2 action on lecithin monolayers.
Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Calcium; Dibucaine; Kinetics; Lidocaine; Membranes, Artificial; Models, Biological; Pancreas; Phosphatidylcholines; Phospholipases; Procaine; Spectrophotometry, Ultraviolet; Surface Properties; Tetracaine | 1976 |
Lidocaine interference in lecithin/sphingomyelin ratios.
Topics: Adult; Amniotic Fluid; Chemical Phenomena; Chemistry; Female; Humans; Lidocaine; Phosphatidylcholines; Pregnancy; Sphingomyelins | 1979 |
Prolongation of canine epidural anesthesia by liposome encapsulation of lidocaine.
Topics: Amines; Anesthesia, Epidural; Animals; Chemistry, Pharmaceutical; Cholesterol; Dogs; Drug Carriers; Evoked Potentials, Somatosensory; Female; Latency Period, Psychological; Lidocaine; Lipid Bilayers; Liposomes; Male; Organophosphates; Phosphatidylcholines; Time Factors | 1992 |
Role of phospholipids in reconstituted cytochrome P450 3A form and mechanism of their activation of catalytic activity.
Topics: Animals; Benzene Derivatives; Benzoflavones; Catalysis; Cholic Acid; Cholic Acids; Cytochrome P-450 Enzyme System; Enzyme Activation; Humans; Lidocaine; NADPH-Ferrihemoprotein Reductase; Nifedipine; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Rabbits; Rats; Testosterone | 1992 |
[Proton magnetic resonance study on the interaction of lidocaine derivatives with lecithin vesicles].
Topics: Lidocaine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines | 1991 |
pH-dependent binding of local anesthetics in single batrachotoxin-activated Na+ channels. Cocaine vs. quaternary compounds.
Topics: Anesthetics, Local; Animals; Batrachotoxins; Binding Sites; Cocaine; Hydrogen-Ion Concentration; Kinetics; Lidocaine; Lipid Bilayers; Models, Biological; Muscles; Naphthalenes; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Pyrrolidinones; Rabbits; Sodium Channels | 1990 |
pH-dependent effects of local anaesthetics in perturbing lipid membranes.
Topics: Anesthetics, Local; Animals; Benzocaine; Brain; Carbamates; Cattle; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Membrane Lipids; Phosphatidylcholines | 1987 |
Ultra-long-duration local anesthesia produced by injection of lecithin-coated methoxyflurane microdroplets.
Topics: Anesthesia, Local; Animals; Bupivacaine; Dose-Response Relationship, Drug; Drug Compounding; Female; Hindlimb; Lidocaine; Methoxyflurane; Phosphatidylcholines; Rats; Rats, Inbred F344; Tail; Time Factors | 1985 |
General and local anaesthetics perturb the fusion of phospholipid vesicles.
Topics: Anesthetics; Anesthetics, Local; Bupivacaine; Calcium; Chromatography, Gel; Ether; Halothane; Lidocaine; Liposomes; Membrane Fusion; Methoxyflurane; Microscopy, Electron; Phosphatidic Acids; Phosphatidylcholines; Temperature | 1985 |
Induction of intracellular acyl-CoA:cholesterol acyltransferase activity in glioblastoma cells by lidocaine.
Topics: Anesthetics, Local; Animals; Cell Line; Cholesterol Esters; Enzyme Induction; Glioma; Lidocaine; Neurons; Oleic Acid; Oleic Acids; Phosphatidylcholines; Rats; Sterol O-Acyltransferase; Time Factors | 1985 |
Sarcoplasmic reticulum. XII. The interaction of 8-anilino-1-naphthalene sulfonate with skeletal muscle microsomes.
Topics: Acetone; Aniline Compounds; Animals; Binding Sites; Calcium Chloride; Chlorides; Chloroform; Fluorescence; Lanthanum; Lidocaine; Lysophosphatidylcholines; Magnesium; Mathematics; Membranes; Methanol; Microsomes; Muscle Proteins; Muscles; Naphthalenes; Phosphatidylcholines; Phospholipases; Phospholipids; Polymyxins; Procaine; Rabbits; Rotation; Sarcoplasmic Reticulum; Serum Albumin; Sucrose; Sulfonic Acids; Temperature; Tetracaine; Viscosity | 1971 |
The importance of the hydrophobic interactions of local anesthetics in the displacement of polyvalent cations from artificial lipid membranes.
Topics: Anesthetics, Local; Deuterium; Europium; Lidocaine; Liposomes; Magnetic Resonance Spectroscopy; Membranes, Artificial; Phosphatidylcholines; Praseodymium; Procaine; Quaternary Ammonium Compounds; Tetracaine; Vibration | 1973 |
Membrane-active agents. Effect of various anesthetics and chlorpromazine on arterial lipid metabolism.
Topics: Acetyl-CoA C-Acyltransferase; Anesthetics, Local; Animals; Arteries; Chlorpromazine; Lidocaine; Lipid Metabolism; Male; Membrane Lipids; Oleic Acids; Phosphatidylcholines; Phospholipids; Rabbits | 1981 |
The effect of anesthetic charge on anesthetic-phospholipid interactions.
Topics: Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry; Gels; Kinetics; Lidocaine; Liposomes; Phosphatidylcholines; Phosphatidylethanolamines; Structure-Activity Relationship | 1981 |
Lidocaine inhibits choline uptake and phosphatidylcholine biosynthesis in human leukemic monocyte-like U937 cells.
Topics: Biological Transport; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Diacylglycerol Cholinephosphotransferase; Humans; Lidocaine; Monocytes; Nucleotidyltransferases; Phosphatidylcholines; Tumor Cells, Cultured | 1994 |
Local anesthetics destabilize lipid membranes by breaking hydration shell: infrared and calorimetry studies.
Topics: Anesthetics, Local; Calorimetry, Differential Scanning; Hydrogen Bonding; Lidocaine; Lipid Bilayers; Mathematics; Membranes; Phosphatidylcholines; Spectrophotometry, Infrared; Temperature; Water | 1994 |
Immobilized artificial membrane (IAM)-HPLC for partition studies of neutral and ionized acids and bases in comparison with the liposomal partition system.
Topics: Alkalies; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anticoagulants; Buffers; Chromatography, High Pressure Liquid; Diazepam; Hydrogen-Ion Concentration; Ions; Kinetics; Lidocaine; Liposomes; Membranes, Artificial; Phosphatidylcholines; Propranolol; Salicylates; Solvents; Temperature; Thermodynamics; Vasodilator Agents; Warfarin | 1999 |
Cubic phases for studies of drug partition into lipid bilayers.
Topics: Anesthetics, Local; Butylamines; Chemistry, Pharmaceutical; Chlormethiazole; Glycerides; Hydrogen-Ion Concentration; Kinetics; Lidocaine; Lipid Bilayers; Octanols; Phosphatidylcholines; Prilocaine; Solubility; Water; X-Ray Diffraction | 1999 |
Spectroscopic evidence for a preferential location of lidocaine inside phospholipid bilayers.
Topics: Deuterium Oxide; Electron Spin Resonance Spectroscopy; Freeze Drying; Lidocaine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Microscopy, Fluorescence; Models, Molecular; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared | 2002 |
Peroxynitrite affects lidocaine by acting on membrane-constituting lipids.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anesthetics, Local; Lidocaine; Lipid Bilayers; Liposomes; Membrane Fluidity; Neurons; Peroxynitrous Acid; Phosphatidylcholines | 2008 |
Increasing membrane interactions of local anaesthetics as hypothetic mechanism for their cardiotoxicity enhanced by myocardial ischaemia.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anesthetics, Local; Animals; Bupivacaine; Cardiolipins; Chemical Phenomena; Fluorescence Polarization; Humans; Lidocaine; Lipid Bilayers; Lipid Peroxidation; Membrane Fluidity; Mitochondrial Membranes; Models, Biological; Myocardial Ischemia; Myocardial Reperfusion Injury; Osmolar Concentration; Peroxynitrous Acid; Phosphatidylcholines | 2012 |
Anesthetics interacting with lipid rafts.
Topics: Anesthetics; Cholesterol; Lidocaine; Lipid Bilayers; Liposomes; Membrane Microdomains; Phosphatidylcholines; Propofol; Sphingomyelins; Tetracaine | 2013 |
Formulation and evaluation of lidocaine base ethosomes for transdermal delivery.
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Chemistry, Pharmaceutical; Cholesterol; Chromatography, High Pressure Liquid; Drug Carriers; Drug Stability; Edema; Erythema; Ethanol; Guinea Pigs; Lidocaine; Liposomes; Pain Threshold; Particle Size; Permeability; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Skin; Skin Absorption; Skin Irritancy Tests | 2013 |
Distribution of local anesthetics between aqueous and liposome phases.
Topics: Anesthetics, Local; Chromatography, Micellar Electrokinetic Capillary; Erythrocytes; Humans; Lidocaine; Lipid Bilayers; Liposomes; Phosphatidylcholines; Phospholipids; Temperature; Water | 2017 |