Page last updated: 2024-09-05

phosphatidylcholines and lapatinib

phosphatidylcholines has been researched along with lapatinib in 2 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(lapatinib)
Trials
(lapatinib)
Recent Studies (post-2010) (lapatinib)
32,2044435,5931,9193051,442

Protein Interaction Comparison

ProteinTaxonomyphosphatidylcholines (IC50)lapatinib (IC50)
Bile salt export pumpHomo sapiens (human)7.375
Epidermal growth factor receptorHomo sapiens (human)0.0827
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0537
Platelet-derived growth factor receptor betaHomo sapiens (human)8.5
D(1A) dopamine receptorSus scrofa (pig)0.06
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)0.1659
Alpha-1A adrenergic receptor Sus scrofa (pig)0.06
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3.2

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Jiang, T; Jiang, X; Pang, X; Pang, Z; Wan, X; Xu, W; Zhang, Q; Zhang, Z; Zhao, J; Zheng, X1
Abel, T; Alonso de Armiño, DJ; Di Lella, S; Fischer, M; Haralampiev, I; Huster, D; Luck, M; Müller, P; Scheidt, HA1

Other Studies

2 other study(ies) available for phosphatidylcholines and lapatinib

ArticleYear
Lapatinib-loaded human serum albumin nanoparticles for the prevention and treatment of triple-negative breast cancer metastasis to the brain.
    Oncotarget, 2016, Jun-07, Volume: 7, Issue:23

    Topics: Administration, Intravenous; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Drug Carriers; Drug Compounding; Drug Stability; Female; Lapatinib; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasm Invasiveness; Phosphatidylcholines; Protein Kinase Inhibitors; Quinazolines; Serum Albumin, Human; Tissue Distribution; Triple Negative Breast Neoplasms

2016
Interaction of the small-molecule kinase inhibitors tofacitinib and lapatinib with membranes.
    Biochimica et biophysica acta. Biomembranes, 2020, 11-01, Volume: 1862, Issue:11

    Topics: Humans; Lapatinib; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Piperidines; Protein Kinase Inhibitors; Pyrimidines

2020