Page last updated: 2024-09-05

phosphatidylcholines and interleukin-8

phosphatidylcholines has been researched along with interleukin-8 in 23 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(interleukin-8)
Trials
(interleukin-8)
Recent Studies (post-2010) (interleukin-8)
32,2044435,59323,5231,1679,990

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.04)18.2507
2000's14 (60.87)29.6817
2010's4 (17.39)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Arnet, B; Doran, JE; Koster, F; Lerch, PG; Pajkrt, D; ten Cate, JW; van der Poll, T; van Deventer, SJ1
Tou, JS; Wang, F; Xu, M1
Friedman, M; Kafoury, RM; Pryor, WA; Salgo, MG; Squadrito, GL; Zou, X1
Ahmad, S; Allen, CB; Harrison, K; Murphy, RC; Uhlson, C; White, CW1
Berliner, JA; Cole, AL; Krutzik, SR; Lucas, RM; Modlin, RL; Nakai, J; Smart, EJ; Subbanagounder, G; Vora, DK; Walton, KA; Yeh, M1
Berliner, JA; Cole, AL; Gharavi, N; Hsieh, X; Walton, KA; Wang, G; Wang, S; Yeh, M1
Mackman, N1
Bergmark, C; Edelstein, C; Getz, GS; Hinman, J; Lipkind, G; Miller, E; Pfaffinger, D; Scanu, AM; Tsimikas, S; Witztum, JL1
Berliner, JA; Choi, J; Cole, AL; Gharavi, NM; Hsieh, X; Mouillesseaux, KP; Reddy, ST; Reed, E; Yeh, M1
Berliner, JA; Choi, J; Cole, AL; Dooley, AN; Fishbein, MC; Gargalovic, P; Hovnanian, T; Kirchgessner, T; Liu, Y; Mouilleseaux, K; Qiao, JH; Shyy, JY; Tulchinsky, D; Vora, DK; Yang, WP; Yeh, M1
Baker, NA; Berliner, JA; Gharavi, NM; Honda, HM; Hsieh, X; Mouillesseaux, KP; Smart, EJ; Yeh, M; Yeung, W1
Pollock, JS; Sullivan, JC1
Erridge, C; Spickett, CM; Webb, DJ1
Berliner, JA; Chen, TT; Gharavi, NM; Graeber, TG; Le, T; Mouillesseaux, KP; Ryvkin, A; Watson, AD; Zimman, A1
Alva, JA; Berliner, JA; Fishbein, M; Gharavi, NM; Hong, L; Johnson, J; Lai, C; Mouillesseaux, KP; Pfeffer, LM; Szeto, WL; Wei, L; Yeh, M; Yeung, W1
Bode, C; Moser, L; Parlesak, A; Schaeckeler, S1
Braun, A; Ehehalt, R; Füllekrug, J; Giese, T; Griffiths, G; Jeliaskova, P; Stremmel, W; Treede, I1
Detrick, MS; Dvoracek, LA; Francis, AD; Kacmarik, KL; Kreisberg, JI; Kreisberg, R; Lee, HM; McKinney, J; Primerano, DA; Santanam, N; Schmid, G1
Curstedt, T; Fehrholz, M; Glaser, K; Kunzmann, S; Papsdorf, M; Speer, CP1
Bochkov, VN; Godschachner, V; Oskolkova, OV1
Borchers, C; Ocana, JA; Rapp, CM; Sahu, RP; Travers, JB; Weyerbacher, J1
Makrantonaki, E; Theodoridis, A; Zouboulis, CC1
Bochkov, V; Gesslbauer, B; Hellauer, K; Oskolkova, OV1

Trials

1 trial(s) available for phosphatidylcholines and interleukin-8

ArticleYear
Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia.
    The Journal of experimental medicine, 1996, Nov-01, Volume: 184, Issue:5

    Topics: Adult; Antigens, CD; Apolipoprotein A-I; Cholesterol; Cross-Over Studies; Double-Blind Method; Endotoxemia; Endotoxins; Granulocytes; Humans; Inflammation; Infusions, Intravenous; Interleukin-6; Interleukin-8; Leukocyte Count; Lipopolysaccharides; Lipoproteins, HDL; Male; Monocytes; Nausea; Pain; Phosphatidylcholines; Placebos; Shivering; Time Factors; Tumor Necrosis Factor-alpha; Vomiting

1996

Other Studies

22 other study(ies) available for phosphatidylcholines and interleukin-8

ArticleYear
Formation of phosphatidic acid and subclasses of phosphatidylethanol in human neutrophils upon interleukin-8 stimulation.
    Cellular signalling, 1999, Volume: 11, Issue:2

    Topics: Chromatography, Thin Layer; Cytochalasin B; Diglycerides; Ethanol; Glycerophospholipids; Humans; Interleukin-8; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Signal Transduction; Time Factors

1999
Induction of inflammatory mediators in human airway epithelial cells by lipid ozonation products.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:6

    Topics: Alkanes; Bronchi; Cells, Cultured; Dinoprostone; Enzyme Activation; Epithelial Cells; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Membrane Lipids; Oxidants, Photochemical; Ozone; Peroxides; Phosphatidylcholines; Phospholipases A; Platelet Activating Factor; Type C Phospholipases

1999
Oxidized phospholipids derived from ozone-treated lung surfactant extract reduce macrophage and epithelial cell viability.
    Chemical research in toxicology, 2002, Volume: 15, Issue:7

    Topics: Animals; Apoptosis; Cattle; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Epithelial Cells; Humans; Interleukin-8; Macrophages, Peritoneal; Mass Spectrometry; Mice; Monocytes; Oxidation-Reduction; Ozone; Phosphatidylcholines; Pulmonary Surfactants

2002
Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Jul-01, Volume: 23, Issue:7

    Topics: Animals; Cattle; Caveolae; Caveolin 1; Caveolins; CD36 Antigens; Cell Membrane; Chemokine CCL2; Endothelial Cells; Humans; Interleukin-1; Interleukin-8; Intracellular Membranes; Lipopolysaccharides; Macrophages; Membrane Glycoproteins; Phosphatidylcholines; Receptors, Cell Surface; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptors; Tumor Necrosis Factor-alpha

2003
Receptors involved in the oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidylinositol-anchored protein.
    The Journal of biological chemistry, 2003, Aug-08, Volume: 278, Issue:32

    Topics: Animals; Aorta; Blotting, Western; CD36 Antigens; Cell Line; Cells, Cultured; CHO Cells; Cricetinae; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Glycosylphosphatidylinositols; HeLa Cells; Humans; Interleukin-8; Lipopolysaccharide Receptors; Lipoproteins, LDL; Membrane Glycoproteins; Mice; Oxygen; Phosphatidylcholines; Precipitin Tests; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Toll-Like Receptor 4; Toll-Like Receptors; Transcription, Genetic; Transfection; Type C Phospholipases

2003
How do oxidized phospholipids inhibit LPS signaling?
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Jul-01, Volume: 23, Issue:7

    Topics: Chemokine CCL2; Interleukin-8; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Oxidation-Reduction; Phosphatidylcholines; Phospholipids

2003
Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a).
    The Journal of biological chemistry, 2003, Dec-26, Volume: 278, Issue:52

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Apolipoproteins A; Binding Sites; Blotting, Western; Cell Line; Cells, Cultured; Culture Media, Conditioned; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Immunoblotting; Interleukin-8; Lipid Metabolism; Lipids; Luminescent Measurements; Lysine; Macaca mulatta; Macrophages; Models, Molecular; Molecular Sequence Data; Oxygen; Phosphatidylcholines; Phosphorus; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Temperature; Time Factors

2003
Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway.
    The Journal of biological chemistry, 2004, Jul-16, Volume: 279, Issue:29

    Topics: Blotting, Western; Cell Nucleus; Cells, Cultured; CSK Tyrosine-Protein Kinase; Cyclic AMP; Cytoplasm; DNA-Binding Proteins; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Genes, Dominant; Humans; Inflammation; Interleukin-8; Kinetics; Models, Biological; NF-kappa B; Oxygen; Phosphatidylcholines; Phospholipids; Phosphorylation; Plasmids; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Time Factors; Trans-Activators; Transfection; Tyrosine

2004
Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products.
    Circulation research, 2004, Oct-15, Volume: 95, Issue:8

    Topics: Animals; Aorta; Arteriosclerosis; beta-Cyclodextrins; Cattle; Caveolin 1; Caveolins; CCAAT-Enhancer-Binding Proteins; Cell Compartmentation; Cell Membrane; Cell Nucleus; Cells, Cultured; Cholesterol; DNA-Binding Proteins; Endoplasmic Reticulum; Endothelial Cells; Endothelium, Vascular; Golgi Apparatus; HeLa Cells; Humans; Hydroxycholesterols; Inflammation; Interleukin-8; Intracellular Signaling Peptides and Proteins; Membrane Lipids; Membrane Proteins; Phosphatidylcholines; Phospholipid Ethers; Recombinant Fusion Proteins; STAT3 Transcription Factor; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection

2004
Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids.
    Circulation research, 2006, Mar-31, Volume: 98, Issue:6

    Topics: Animals; Atherosclerosis; Cattle; Cells, Cultured; CSK Tyrosine-Protein Kinase; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Humans; Interleukin-8; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phospholipid Ethers; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; src-Family Kinases; Sterol Regulatory Element Binding Proteins; Superoxides

2006
Coupled and uncoupled NOS: separate but equal? Uncoupled NOS in endothelial cells is a critical pathway for intracellular signaling.
    Circulation research, 2006, Mar-31, Volume: 98, Issue:6

    Topics: Animals; Atherosclerosis; Endothelial Cells; Humans; Interleukin-8; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylcholines; Phosphorylation; Signal Transduction; Sterol Regulatory Element Binding Proteins; Superoxides

2006
Toll-like receptor 4 signalling is neither sufficient nor required for oxidised phospholipid mediated induction of interleukin-8 expression.
    Atherosclerosis, 2007, Volume: 193, Issue:1

    Topics: Atherosclerosis; Base Sequence; Cell Line; Cells, Cultured; DNA Primers; Endothelial Cells; Gene Expression; Humans; Interleukin-8; Lipids; NF-kappa B; Phosphatidylcholines; Promoter Regions, Genetic; Recombinant Proteins; Signal Transduction; Toll-Like Receptor 4; Transfection

2007
Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:2

    Topics: Cell Line; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Humans; Interleukin-8; Mitogen-Activated Protein Kinase 3; Phosphatidylcholines; Phosphorylation; Receptors, LDL; RNA, Small Interfering; Sterol Regulatory Element Binding Proteins; Thromboplastin; Transcription, Genetic; Vascular Endothelial Growth Factor Receptor-2

2007
Role of the Jak/STAT pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo.
    The Journal of biological chemistry, 2007, Oct-26, Volume: 282, Issue:43

    Topics: Animals; Aorta; Atherosclerosis; Capillaries; Cells, Cultured; Chromatin Immunoprecipitation; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; In Vitro Techniques; Interleukin-8; Janus Kinase 2; Mice; Mice, Knockout; Models, Biological; Oxidation-Reduction; Phosphatidylcholines; Phosphorylation; Plasmids; RNA, Small Interfering; STAT3 Transcription Factor; Time Factors; Trans-Activators; Transcription, Genetic; Transfection

2007
Conjugated primary bile salts reduce permeability of endotoxin through intestinal epithelial cells and synergize with phosphatidylcholine in suppression of inflammatory cytokine production.
    Critical care medicine, 2007, Volume: 35, Issue:10

    Topics: Bile Acids and Salts; Cells, Cultured; Endotoxins; Humans; Inflammation; Interleukin-10; Interleukin-6; Interleukin-8; Intestinal Mucosa; Permeability; Phosphatidylcholines; Tumor Necrosis Factor-alpha

2007
TNF-alpha-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells.
    BMC gastroenterology, 2009, Jul-13, Volume: 9

    Topics: Cell Line; Chemokine CCL2; Cytokines; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Intestinal Mucosa; Matrix Metalloproteinase 1; NF-kappa B; Phosphatidylcholines; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha; Up-Regulation

2009
Lovastatin inhibits oxidized L-A-phosphatidylcholine B-arachidonoyl-gamma-palmitoyl (ox-PAPC)-stimulated interleukin-8 mRNA and protein synthesis in human aortic endothelial cells by depleting stores of geranylgeranyl pyrophosphate.
    Atherosclerosis, 2010, Volume: 208, Issue:1

    Topics: Aorta; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Humans; Interleukin-8; Lovastatin; Phosphatidylcholines; Polyisoprenyl Phosphates; Protein Biosynthesis; RNA, Messenger

2010
The new generation synthetic reconstituted surfactant CHF5633 suppresses LPS-induced cytokine responses in human neonatal monocytes.
    Cytokine, 2016, Volume: 86

    Topics: Cytokines; Fetal Blood; Flow Cytometry; Humans; Infant, Newborn; Interleukin-10; Interleukin-1beta; Interleukin-8; Lipopolysaccharide Receptors; Lipopolysaccharides; Monocytes; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; Real-Time Polymerase Chain Reaction; Respiratory Distress Syndrome, Newborn; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2016
Off-Target Anti-Inflammatory Activity of the P2X7 Receptor Antagonist AZ11645373.
    Inflammation, 2017, Volume: 40, Issue:2

    Topics: Anti-Inflammatory Agents; Human Umbilical Vein Endothelial Cells; Humans; Inflammasomes; Interleukin-8; Phosphatidylcholines; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; RNA, Messenger; Thiazoles; Transcriptional Activation

2017
Acute Ethanol Exposure Augments Low-Dose UVB-Mediated Systemic Immunosuppression via Enhanced Production of Platelet-Activating Factor Receptor Agonists.
    The Journal of investigative dermatology, 2019, Volume: 139, Issue:7

    Topics: Animals; Cell Line; Ethanol; Humans; Immune Tolerance; Immunosuppression Therapy; Interleukin-8; Keratinocytes; Mice; Mice, Knockout; Oxidation-Reduction; Phosphatidylcholines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Ultraviolet Rays

2019
Inflammation and thrombo-occlusive vessel signalling in benign atrophic papulosis (Köhlmeier-Degos disease).
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2022, Volume: 36, Issue:11

    Topics: Antibodies, Antinuclear; Antibodies, Antiphospholipid; Antigens, Nuclear; Atrophy; Cardiolipins; Connective Tissue Diseases; Ethanolamines; Humans; Immunoglobulin G; Immunoglobulin M; Inflammation; Interleukin-6; Interleukin-8; Malignant Atrophic Papulosis; Peptide Hydrolases; Peroxidase; Phosphatidylcholines; Phosphatidylinositols; Phosphatidylserines; Sphingomyelins; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vasculitis

2022
Pharmacological heat-shock protein inducers and chemical chaperones inhibit upregulation of interleukin-8 by oxidized phospholipids.
    Inflammopharmacology, 2023, Volume: 31, Issue:3

    Topics: Animals; Endothelial Cells; Heat-Shock Proteins; Humans; Interleukin-8; Phosphatidylcholines; Phospholipids; Up-Regulation

2023