Page last updated: 2024-09-05

phosphatidylcholines and idb 1016

phosphatidylcholines has been researched along with idb 1016 in 19 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(idb 1016)
Trials
(idb 1016)
Recent Studies (post-2010) (idb 1016)
32,2044435,5932461

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (47.37)18.2507
2000's9 (47.37)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Conti, M; Magistretti, MJ; Malandrino, S1
Gatti, G; Perucca, E; Schandalik, R1
Albano, E; Carini, R; Comoglio, A; Poli, G1
Albano, E; Basaga, H; Busolin, D; Carini, R; Comoglio, A; Leonarduzzi, G; Magistretti, MJ; Morazzoni, P; Poli, G; Tomasi, A1
Albano, E; Comoglio, A; Malandrino, S; Poli, G; Tomasi, A1
Gatti, G; Perucca, E1
Perucca, E; Schandalik, R1
Buzzelli, G; Duchini, A; Giusti, A; Lampertico, M; Marena, C; Moscarella, S1
Aras, I; Basaga, H; Poli, G; Tekkaya, C1
Apollonio, P; Bombardelli, E; Distefano, M; Ferlini, C; Gallo, D; Giacomelli, S; Mancuso, S; Morazzoni, P; Riva, A; Scambia, G1
Apollonio, P; Bombardelli, E; Ferlini, C; Gallo, D; Giacomelli, S; Morazzoni, P; Prislei, S; Raspaglio, G; Riva, A; Scambia, G1
Bendia, E; Benedetti, A; Candelaresi, C; De Minicis, S; Di Sario, A; Marzioni, M; Omenetti, A; Taffetani, S1
Donnini, A; Morazzoni, P; Orlando, F; Papalini, F; Pierpaoli, S; Provinciali, M; Riva, A; Smorlesi, A1
Filburn, CR; Griffin, DW; Kettenacker, R1
Berry, DP; Boocock, DJ; Brown, VA; Cai, H; Gescher, AJ; Hoh, CS; Marczylo, TH; Steward, WP1
Brown, K; Gescher, AJ; Steward, WP; Verschoyle, RD1
Brown, K; Gescher, AJ; Greaves, P; Marsden, DA; Patel, K; Steward, WP; Verschoyle, RD1
Bares, JM; Berger, J; Kowdley, KV; Messner, DJ; Nelson, JE; Schildt, S; Standish, LJ1
Flaig, TW; Goyal, A; Greenlee, H; Gustafson, DL; Hansen, RJ; Jacobson, JS; Kelly, K; Ladas, E; Lee, V; Lunghofer, PJ; Narayan, R; Rodriguez, R; Siegel, AB; Tsai, WY; Wu, DP1

Trials

4 trial(s) available for phosphatidylcholines and idb 1016

ArticleYear
A pilot study on the liver protective effect of silybin-phosphatidylcholine complex (IdB1016) in chronic active hepatitis.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:9

    Topics: Adult; Aged; Antioxidants; Copper; Female; Free Radical Scavengers; Hepatitis, Chronic; Humans; Liver; Liver Function Tests; Male; Malondialdehyde; Middle Aged; Phosphatidylcholines; Pilot Projects; Silymarin; Zinc

1993
Bioavailability of a silybin-phosphatidylcholine complex in dogs.
    Journal of veterinary pharmacology and therapeutics, 2007, Volume: 30, Issue:2

    Topics: Administration, Oral; Animals; Antioxidants; Area Under Curve; Biological Availability; Dogs; Female; Male; Phosphatidylcholines; Phytotherapy; Plant Extracts; Silybin; Silymarin

2007
Silybin treatment is associated with reduction in serum ferritin in patients with chronic hepatitis C.
    Journal of clinical gastroenterology, 2008, Volume: 42, Issue:8

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Ferritins; Hepatitis C, Chronic; Humans; Iron-Binding Proteins; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Phosphatidylcholines; Silybum marianum; Silymarin; Transferrin

2008
A phase I dose-finding study of silybin phosphatidylcholine (milk thistle) in patients with advanced hepatocellular carcinoma.
    Integrative cancer therapies, 2014, Volume: 13, Issue:1

    Topics: Antioxidants; Carcinoma, Hepatocellular; Disease Progression; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Phosphatidylcholines; Silybin; Silybum marianum; Silymarin

2014

Other Studies

15 other study(ies) available for phosphatidylcholines and idb 1016

ArticleYear
Protective activity of silipide on liver damage in rodents.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:4

    Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ethanol; Female; Galactosamine; Male; Phosphatidylcholines; Praseodymium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Silymarin

1992
Pharmacokinetics of silybin in bile following administration of silipide and silymarin in cholecystectomy patients.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:7

    Topics: Adult; Aged; Bile; Cholecystectomy; Chromatography, High Pressure Liquid; Female; Humans; Lignans; Lignin; Male; Middle Aged; Phosphatidylcholines; Silymarin

1992
Lipid peroxidation and irreversible damage in the rat hepatocyte model. Protection by the silybin-phospholipid complex IdB 1016.
    Biochemical pharmacology, 1992, May-28, Volume: 43, Issue:10

    Topics: 1-Propanol; Animals; Antioxidants; Benzene Derivatives; Bromotrichloromethane; Dose-Response Relationship, Drug; Drug Interactions; Lipid Peroxidation; Liver; Male; Malondialdehyde; Models, Biological; Phosphatidylcholines; Propanols; Rats; Rats, Inbred Strains; Silymarin

1992
Studies on the antioxidant and free radical scavenging properties of IdB 1016 a new flavanolignan complex.
    Free radical research communications, 1990, Volume: 11, Issue:1-3

    Topics: Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Benzene Derivatives; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Free Radicals; Iron; Lipid Peroxidation; Male; Malondialdehyde; Microsomes, Liver; NADH Dehydrogenase; NADP; Oxidation-Reduction; Phosphatidylcholines; Rats; Rats, Inbred Strains; Silymarin

1990
Scavenging effect of silipide, a new silybin-phospholipid complex, on ethanol-derived free radicals.
    Biochemical pharmacology, 1995, Oct-12, Volume: 50, Issue:8

    Topics: Animals; Antioxidants; Bile; Electron Spin Resonance Spectroscopy; Ethanol; Free Radical Scavengers; Free Radicals; Male; Microsomes, Liver; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Silymarin; Spin Trapping

1995
Plasma concentrations of free and conjugated silybin after oral intake of a silybin-phosphatidylcholine complex (silipide) in healthy volunteers.
    International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:11

    Topics: Administration, Oral; Adult; Female; Humans; Male; Phosphatidylcholines; Reference Values; Silymarin

1994
Pharmacokinetics of silybin following oral administration of silipide in patients with extrahepatic biliary obstruction.
    Drugs under experimental and clinical research, 1994, Volume: 20, Issue:1

    Topics: Adult; Aged; Antioxidants; Cholestasis, Extrahepatic; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Phosphatidylcholines; Silymarin

1994
Free radical scavenging and antioxidative properties of 'silibin' complexes on microsomal lipid peroxidation.
    Cell biochemistry and function, 1997, Volume: 15, Issue:1

    Topics: Animals; Antioxidants; Benzene Derivatives; Free Radical Scavengers; Iron; Lipid Peroxidation; Liver; Lung; Microsomes; NADP; Oxidants; Phosphatidylcholines; Sheep; Silymarin

1997
Silybin and its bioavailable phospholipid complex (IdB 1016) potentiate in vitro and in vivo the activity of cisplatin.
    Life sciences, 2002, Feb-08, Volume: 70, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cisplatin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Mice; Mice, Nude; Neoplasms, Experimental; Neovascularization, Pathologic; Ovarian Neoplasms; Phosphatidylcholines; Silymarin; Tumor Cells, Cultured

2002
Antitumour activity of the silybin-phosphatidylcholine complex, IdB 1016, against human ovarian cancer.
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:16

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; DNA, Complementary; Drug Evaluation; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Ovarian Neoplasms; Phosphatidylcholines; Silymarin; Vascular Endothelial Growth Factor A

2003
Hepatoprotective and antifibrotic effect of a new silybin-phosphatidylcholine-Vitamin E complex in rats.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2005, Volume: 37, Issue:11

    Topics: Animals; Antioxidants; Biological Availability; Drug Combinations; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Silymarin; Tissue Inhibitor of Metalloproteinase-1; Vitamin E

2005
Effect of the silybin-phosphatidylcholine complex (IdB 1016) on the development of mammary tumors in HER-2/neu transgenic mice.
    Cancer research, 2007, Mar-01, Volume: 67, Issue:5

    Topics: Animals; Apoptosis; Carcinoma; Cell Proliferation; Cellular Senescence; Drug Screening Assays, Antitumor; Female; Humans; Leukemic Infiltration; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Phosphatidylcholines; Receptor, ErbB-2; Silymarin; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2007
Quantitation of silibinin, a putative cancer chemopreventive agent derived from milk thistle (Silybum marianum), in human plasma by high-performance liquid chromatography and identification of possible metabolites.
    Journal of agricultural and food chemistry, 2007, Apr-04, Volume: 55, Issue:7

    Topics: Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Humans; Phosphatidylcholines; Silybin; Silybum marianum; Silymarin; Stereoisomerism

2007
Consumption of silibinin, a flavonolignan from milk thistle, and mammary cancer development in the C3(1) SV40 T,t antigen transgenic multiple mammary adenocarcinoma (TAg) mouse.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:2

    Topics: Animals; Antigens, Polyomavirus Transforming; Female; Flavonolignans; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Molecular Structure; Phosphatidylcholines; Silybin; Silybum marianum; Silymarin; Stereoisomerism

2008
Evaluation of the cancer chemopreventive efficacy of silibinin in genetic mouse models of prostate and intestinal carcinogenesis: relationship with silibinin levels.
    European journal of cancer (Oxford, England : 1990), 2008, Volume: 44, Issue:6

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Chromatography, High Pressure Liquid; Drug Evaluation; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Prostatic Neoplasms; Silybin; Silymarin

2008