phosphatidylcholines has been researched along with diclofenac in 27 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (diclofenac) | Trials (diclofenac) | Recent Studies (post-2010) (diclofenac) |
|---|---|---|---|---|---|
| 32,204 | 443 | 5,593 | 8,874 | 1,874 | 3,616 |
| Protein | Taxonomy | phosphatidylcholines (IC50) | diclofenac (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 1.9 | |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 0.003 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 1.3376 | |
| Interleukin-8 | Homo sapiens (human) | 0.008 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.0415 | |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | 0.5 | |
| C-X-C chemokine receptor type 1 | Homo sapiens (human) | 0.012 | |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | 0.5 | |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | 0.5 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.4165 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 0.5 | |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | 0.5 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 1.6867 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.0502 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 4 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 0.5 | |
| P2Y purinoceptor 12 | Rattus norvegicus (Norway rat) | 0.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.70) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 14 (51.85) | 29.6817 |
| 2010's | 6 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamada, A; Katagi, T; Nishihata, T; Takahashi, K; Tamagawa, S; Yoshitomi, H | 1 |
| Egashira, T; Takayama, F; Yamanaka, Y | 1 |
| Aldini, G; Carini, M; Macciocchi, A; Maffei Facino, R; Saibene, L | 1 |
| Egashira, T; Kudo, Y; Takayama, F; Yamanaka, Y | 1 |
| Jaitely, V; Vyas, SP | 1 |
| Cicero, MR; Fioravanti, A; Manopulo, R; Marcolongo, R; Nerucci, F | 1 |
| Anderson, K; Grace, D; Rogers, J; Skeith, K | 1 |
| Chung, H; Jeong, SY; Kim, TW; Kwon, IC; Kwon, M | 1 |
| Kanzaki, Y; Nakamura, Y; Suzuki, N; Watanabe, Y | 1 |
| Conte, A; Mautone, G; Petrini, M; Ronca, G | 1 |
| Duruz, H; Liguori, V; Mahler, F; Mahler, P; Mautone, G; Ramazzina, M | 1 |
| Boinpally, RR; Devraj, G; Jasti, BR; Poondru, S; Zhou, SL | 1 |
| Oliveira, AG; Oliveira, ON; Scarpa, MV; Souza, SM | 1 |
| Lopes, LB; Oliveira, AG; Rodrigues, DC; Santilli, CV; Scarpa, MV; Silva, GV | 1 |
| Ferreira, H; Lima, JL; Lúcio, M; Matos, C; Reis, S | 1 |
| Gide, PS; Jadhav, KR; Kadam, VJ; Pisal, SS; Shaikh, IM | 1 |
| Aserin, A; Danino, D; Garti, N; Spernath, A; Ziserman, L | 1 |
| Aserin, A; Garti, N; Sintov, AC; Spernath, A | 1 |
| Hunt, AN; Kohler, JA; Koster, G; Macken, M; Postle, AD | 1 |
| Boros, M; Eros, G; Ghyczy, M; Gurabi, D; Hartmann, P; Horváth, G; Németh, I; Szabó, A | 1 |
| Rawat, MS; Semalty, A; Semalty, M; Singh, D | 1 |
| Amsalem, O; Aserin, A; Garti, N | 1 |
| Bhandari, A; Gaur, PK; Kumar, Y; Mishra, S; Purohit, S | 1 |
| Castangia, I; Fadda, AM; Fernàndez-Busquets, X; Lampis, S; Manca, ML; Manconi, M; Matricardi, P; Sinico, C | 1 |
| Jain, S; Lin, S; Madan, P; Patel, N | 1 |
| Castangia, I; Catalán-Latorre, A; Diez-Sales, O; Fadda, AM; Fernàndez-Busquets, X; Manca, ML; Manconi, M; Matricardi, P; Nácher, A | 1 |
| Castangia, I; Cencetti, C; Fadda, AM; Maccioni, AM; Manca, ML; Manconi, M; Matricardi, P; Nacher, A; Sales, OD; Valenti, D; Zaru, M | 1 |
4 trial(s) available for phosphatidylcholines and diclofenac
| Article | Year |
|---|---|
Double-blind controlled clinical study of the efficacy and tolerability of diclofenac-N-(2-hydroxyethyl)-pyrrolidine lecithin gel compared with diclofenac-N-(2-hydroxyethyl)-pyrrolidine gel in patients with peri and extraarticular inflammatory diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Diclofenac; Double-Blind Method; Edema; Female; Gels; Humans; Inflammation; Male; Middle Aged; Pain; Phosphatidylcholines; Rheumatic Diseases | 1999 |
Topical diclofenac versus placebo: a double blind, randomized clinical trial in patients with osteoarthritis of the knee.
Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Compounding; Female; Humans; Knee Joint; Male; Middle Aged; Osteoarthritis, Knee; Phosphatidylcholines; Placebos; Severity of Illness Index; Treatment Outcome | 1999 |
Effect of lecithin on epicutaneous absorption of diclofenac epolamine.
Topics: Adjuvants, Pharmaceutic; Administration, Cutaneous; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chemistry, Pharmaceutical; Chromatography, Gas; Cross-Over Studies; Diclofenac; Female; Forearm; Gels; Humans; Male; Middle Aged; Phosphatidylcholines; Skin Absorption | 2002 |
Double-blind, randomized, controlled study on the efficacy and safety of a novel diclofenac epolamine gel formulated with lecithin for the treatment of sprains, strains and contusions.
Topics: Acetaminophen; Administration, Topical; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Ankle Injuries; Anti-Inflammatory Agents; Contusions; Diclofenac; Double-Blind Method; Female; Gels; Humans; Knee Injuries; Leg Injuries; Male; Middle Aged; Pain Measurement; Phosphatidylcholines; Prospective Studies; Sprains and Strains | 2003 |
23 other study(ies) available for phosphatidylcholines and diclofenac
| Article | Year |
|---|---|
Release of sodium diclofenac from vehicles prepared with hydrogenated soya lecithin and methyl palmitate.
Topics: Diclofenac; Glycine max; Palmitates; Palmitic Acids; Pharmaceutical Vehicles; Phosphatidylcholines | 1988 |
Effect of diclofenac, a non-steroidal anti-inflammatory drug, on lipid peroxidation caused by ischemia-reperfusion in rat liver.
Topics: Animals; Diclofenac; Free Radical Scavengers; Lipid Peroxidation; Liver; Liver Diseases; Male; Microsomes, Liver; NADP; Phosphatidylcholines; Rats; Rats, Wistar; Reperfusion Injury; Vitamin E | 1994 |
Antioxidant profile of nimesulide, indomethacin and diclofenac in phosphatidylcholine liposomes (PCL) as membrane model.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Diclofenac; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Indomethacin; Liposomes; Membranes, Artificial; Models, Biological; Phosphatidylcholines; Sulfonamides | 1993 |
Effects of anti-free radical interventions on phosphatidylcholine hydroperoxide in plasma after ischemia-reperfusion in the liver of rats.
Topics: Animals; Ascorbic Acid; Chromatography, High Pressure Liquid; Diclofenac; Free Radicals; Ischemia; Liver; Male; Phosphatidylcholines; Rats; Rats, Wistar; Reperfusion Injury; Time Factors | 1993 |
Development and characterisation of supramolecular autovectoring system for selective drug delivery.
Topics: Animals; Crystallization; Diclofenac; Diffusion; Drug Delivery Systems; Female; In Vitro Techniques; Liver; Male; Phosphatidylcholines; Rats; Temperature; Tissue Distribution; Viscosity; X-Ray Diffraction | 1999 |
Oil components modulate physical characteristics and function of the natural oil emulsions as drug or gene delivery system.
Topics: Animals; Antibiotics, Antitubercular; Chemical Phenomena; Chemistry, Physical; Chlorocebus aethiops; COS Cells; Cyclooxygenase Inhibitors; Diclofenac; DNA; Drug Delivery Systems; Emulsions; Escherichia coli; Oils; Particle Size; Phosphatidylcholines; Plasmids; Rifampin; Surface Tension; Transfection; Viscosity | 2001 |
Intercalation compounds of layered materials for drug delivery use. II. Diclofenac sodium.
Topics: Aluminum Silicates; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Drug Delivery Systems; Phosphatidylcholines; Thermogravimetry; Wettability; X-Ray Diffraction | 2001 |
Lecithin vesicles for topical delivery of diclofenac.
Topics: Administration, Topical; Diclofenac; Diffusion Chambers, Culture; Drug Delivery Systems; Epidermis; Humans; In Vitro Techniques; Phosphatidylcholines | 2003 |
Study of the diclofenac/phospholipid interactions with liposomes and monolayers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Glycine max; Kinetics; Light; Liposomes; Phosphatidylcholines; Phospholipids; Scattering, Radiation; Surface Properties; Surface Tension; Water | 2004 |
Studies on the encapsulation of diclofenac in small unilamellar liposomes of soya phosphatidylcholine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Coloring Agents; Diclofenac; Drug Delivery Systems; Liposomes; Micelles; Models, Biological; Particle Size; Phosphates; Phosphatidylcholines; Quaternary Ammonium Compounds; Soybean Oil; Surface Tension | 2004 |
Effects of diclofenac on EPC liposome membrane properties.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Egg Yolk; Fluorescence Polarization; Hydrogen-Ion Concentration; Liposomes; Membrane Fluidity; Membrane Potentials; Models, Biological; Phosphatidylcholines; Spectrophotometry | 2005 |
Topical delivery of aceclofenac from lecithin organogels: preformulation study.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Carriers; Drug Compounding; Gels; In Vitro Techniques; Membranes, Artificial; Oleic Acids; Phase Transition; Phosphatidylcholines; Rats; Skin Absorption; Solubility; Viscosity; Water | 2006 |
Phosphatidylcholine embedded microemulsions: physical properties and improved Caco-2 cell permeability.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Diclofenac; Drug Carriers; Drug Compounding; Electric Conductivity; Emulsions; Humans; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Mineral Oil; Molecular Structure; Permeability; Pharmaceutical Preparations; Phosphatidylcholines; Surface Properties; Surface-Active Agents; Viscosity | 2007 |
Phosphatidylcholine embedded micellar systems: enhanced permeability through rat skin.
Topics: Administration, Topical; Animals; Cell Membrane; Diclofenac; Diffusion Chambers, Culture; Drug Delivery Systems; Emulsions; Male; Micelles; Permeability; Phase Transition; Phosphatidylcholines; Propylene Glycol; Rats; Rats, Sprague-Dawley; Skin; Solubility; Surface Properties; Surface-Active Agents; Time Factors | 2008 |
Diclofenac mediated derangement of neuroblastoma cell lipidomic profiles is accompanied by increased phosphatidylcholine biosynthesis.
Topics: Diclofenac; Diglycerides; Humans; Lipid Metabolism; Neuroblastoma; Phosphatidylcholines; Phosphatidylinositols; Phosphatidylserines; Phospholipase A2 Inhibitors; Phospholipases A2; Tumor Cells, Cultured | 2008 |
Anti-inflammatory effects of phosphatidylcholine in neutrophil leukocyte-dependent acute arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Hyperalgesia; Knee Joint; Male; Microcirculation; Neutrophils; Phosphatidylcholines; Rats; Rats, Wistar; Synovial Membrane | 2009 |
Development and physicochemical evaluation of pharmacosomes of diclofenac.
Topics: Chemistry, Pharmaceutical; Diclofenac; Drug Carriers; Drug Evaluation, Preclinical; Phosphatidylcholines; Phospholipids; Solubility; Spectrophotometry, Ultraviolet; Surface Properties; X-Ray Diffraction | 2009 |
Phospholipids-embedded fully dilutable liquid nanostructures. Part 2: The role of sodium diclofenac.
Topics: Diclofenac; Diffusion; Electric Conductivity; Esters; Glycerol; Hydrogen-Ion Concentration; Light; Magnetic Resonance Spectroscopy; Nanostructures; Particle Size; Phosphatidylcholines; Propylene Glycol; Scattering, Radiation; Solubility; Sucrose; Surface Properties; Triacetin; Viscosity; Water | 2010 |
Development and characterization of stable nanovesicular carrier for drug delivery.
Topics: Chemistry, Pharmaceutical; Diclofenac; Drug Liberation; Drug Stability; Liposomes; Nanostructures; Phosphatidylcholines | 2014 |
Effect of diclofenac and glycol intercalation on structural assembly of phospholipid lamellar vesicles.
Topics: Calorimetry, Differential Scanning; Diclofenac; Drug Compounding; Ethylene Glycols; Intercalating Agents; Liposomes; Phosphatidylcholines; Propylene Glycol; Rheology; X-Ray Diffraction | 2013 |
Quality by design approach for formulation, evaluation and statistical optimization of diclofenac-loaded ethosomes via transdermal route.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Cholesterol; Diclofenac; Excipients; Male; Phosphatidylcholines; Rats, Sprague-Dawley; Skin; Skin Absorption | 2015 |
Effects of ethanol and diclofenac on the organization of hydrogenated phosphatidylcholine bilayer vesicles and their ability as skin carriers.
Topics: Animals; Diclofenac; Ethanol; Hydrogen; In Vitro Techniques; Lipid Bilayers; Phosphatidylcholines; Skin; Swine | 2015 |
Glycerosomes: Use of hydrogenated soy phosphatidylcholine mixture and its effect on vesicle features and diclofenac skin penetration.
Topics: Animals; Cells, Cultured; Diclofenac; Drug Delivery Systems; Glycerol; Glycine max; Humans; Hydrogenation; Keratinocytes; Organ Culture Techniques; Phosphatidylcholines; Skin Absorption; Swine | 2016 |