Page last updated: 2024-09-05

phosphatidylcholines and dactinomycin

phosphatidylcholines has been researched along with dactinomycin in 25 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(dactinomycin)
Trials
(dactinomycin)
Recent Studies (post-2010) (dactinomycin)
32,2044435,59319,045355969

Protein Interaction Comparison

ProteinTaxonomyphosphatidylcholines (IC50)dactinomycin (IC50)
RAD51Homo sapiens (human)32.1
Growth factor receptor-bound protein 2Homo sapiens (human)5
Discoidin domain-containing receptor 2Homo sapiens (human)9
Growth factor receptor-bound protein 2 Mus musculus (house mouse)5

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199020 (80.00)18.7374
1990's3 (12.00)18.2507
2000's1 (4.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dmitriev, BA; Koshkina, NV; L'vov, VL; Omel'yanenko, VG; Petrov, AB; Torchilin, VP; Trubetskoy, VS1
Boland, R; de Boland, AR1
Clark, MA; Crooke, ST; Godfrey, RW; Grillone, LR; Stassen, F1
Chu, AJ; Dynia, DW; Gross, I; Ingleson, LD; Rooney, SA; Smart, DA; Wilson, CM1
Boland, R; de Boland, AR; Drittanti, L1
Floros, J; Post, M; Smith, BT1
Misra, UK; Narayan, S; Sriram, K; Tyagi, SR1
Plagemann, PG1
Kaiser, W1
Cleveland, PH; Plagemann, PG; Shea, MA1
Jakoi, L; Quarfordt, SH1
Farrell, PM; Zachman, RD1
Gregoriadis, G1
Acheampong-Mensah, D; Feuer, G1
Burke, DC; Vance, DE1
Nelson, JD; Sribney, M1
Pfefferkorn, ER; Waite, MR1
Ohanian, SH; Schlager, SI1
Cerny, EA; Jonah, MM; Macek, CM; Rahman, YE; Raphael, L; Sengupta, J; Tom, BH1
Kaye, SB; Ryman, BE1
Hidi, R; Touqui, L; Vargaftig, BB1
Matsuura, T; Ross, AC1
GREEN, DE; JURTSHUK, P; SEKUZU, I1
Wong, A1
Li, Q; Ma, Y; Mu, X; Song, L; Wang, D; Yin, R; Zhao, X1

Other Studies

25 other study(ies) available for phosphatidylcholines and dactinomycin

ArticleYear
FITC-labeled lipopolysaccharide: use as a probe for liposomal membrane incorporation studies.
    FEBS letters, 1990, Aug-20, Volume: 269, Issue:1

    Topics: Animals; Cholesterol; Dactinomycin; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescence Polarization; Lipopolysaccharides; Liposomes; Mice; Mice, Inbred CBA; Neisseria meningitidis; Phosphatidylcholines; Sonication; Spectrometry, Fluorescence; Thiocyanates

1990
Suppression of 1,25-dihydroxy-vitamin D3-dependent calcium transport by protein synthesis inhibitors and changes in phospholipids in skeletal muscle.
    Biochimica et biophysica acta, 1985, May-30, Volume: 845, Issue:2

    Topics: Animals; Biological Transport; Calcitriol; Calcium; Chick Embryo; Chickens; Cycloheximide; Dactinomycin; Muscle Proteins; Muscles; Phosphatidylcholines; Phospholipids; Phosphorus; Puromycin; RNA; Sphingomyelins

1985
Vasopressin induces V1 receptors to activate phosphatidylinositol- and phosphatidylcholine-specific phospholipase C and stimulates the release of arachidonic acid by at least two pathways in the smooth muscle cell line, A-10.
    The Journal of biological chemistry, 1988, Feb-25, Volume: 263, Issue:6

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Cell Line; Cycloheximide; Dactinomycin; GTP-Binding Proteins; Lipid Metabolism; Models, Biological; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphatidylcholines; Rats; Receptors, Angiotensin; Receptors, Vasopressin; Time Factors; Type C Phospholipases; Vasopressins; Virulence Factors, Bordetella

1988
Glucocorticoid stimulation of choline-phosphate cytidylyltransferase activity in fetal rat lung: receptor-response relationships.
    Biochimica et biophysica acta, 1986, Sep-19, Volume: 888, Issue:2

    Topics: Animals; Cell Compartmentation; Choline-Phosphate Cytidylyltransferase; Dactinomycin; Dexamethasone; Glucocorticoids; Lung; Nucleotidyltransferases; Organ Culture Techniques; Phosphatidylcholines; Rats; Receptors, Glucocorticoid

1986
Changes in muscle lipid metabolism induced in vitro by 1,25-dihydroxy-vitamin D-3.
    Biochimica et biophysica acta, 1987, Mar-13, Volume: 918, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Calcitriol; Chick Embryo; Choline; Cycloheximide; Dactinomycin; Ethanolamine; Ethanolamines; Glycerol; In Vitro Techniques; Lipid Metabolism; Muscles; Phosphatidylcholines; Phosphatidylethanolamines; Vitamin D Deficiency

1987
Glucocorticoids affect the synthesis of pulmonary fibroblast-pneumonocyte factor at a pretranslational level.
    The Journal of biological chemistry, 1985, Feb-25, Volume: 260, Issue:4

    Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Fibroblast Growth Factors; Fibroblasts; Glucocorticoids; Hydrocortisone; Lung; Phosphatidylcholines; Protein Biosynthesis; Rats; RNA, Messenger

1985
Induction of cytochrome P-450 and phosphatidylcholine synthesis by endosulfan in liver of rats: effect of quality of dietary proteins.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 1985, Volume: 20, Issue:6

    Topics: Animals; Body Weight; Cytochrome P-450 Enzyme System; Dactinomycin; Diet; Dietary Proteins; Endosulfan; Enzyme Induction; Liver; Organ Size; Phosphatidylcholines; Rats; Rats, Inbred Strains

1985
Choline metabolism and membrane formation in rat hepatoma cells grown in suspension culture. I. Incorporation of choline into phosphatidylcholine of mitochondria and other membranous structures and effect of metabolic inhibitors.
    Archives of biochemistry and biophysics, 1968, Volume: 128, Issue:1

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Membrane; Centrifugation, Density Gradient; Chloramphenicol; Choline; Chromatography, Thin Layer; Culture Techniques; Cycloheximide; Dactinomycin; Dihydrolipoamide Dehydrogenase; Electron Transport Complex IV; Glucose-6-Phosphatase; Liver Neoplasms; Malate Dehydrogenase; Microscopy, Electron; Mitochondria; Phosphatidylcholines; Puromycin; Rats; Tritium; Uridine

1968
Incorporation of phospholipid precursors into isolated rat liver mitochondria.
    European journal of biochemistry, 1969, Volume: 8, Issue:1

    Topics: Amino Acids; Amino Alcohols; Animals; Bacteria; Carbon Isotopes; Centrifugation, Density Gradient; Choline; Chromatography, Thin Layer; Dactinomycin; Depression, Chemical; Glycerophosphates; Hydrogen-Ion Concentration; Kinetics; Leucine; Liver; Lysophosphatidylcholines; Male; Microsomes; Mitochondria, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Puromycin; Rats; Serine

1969
Effect of mengovirus replication on choline metabolism and membrane formation in novikoff hepatoma cells.
    Journal of virology, 1970, Volume: 6, Issue:6

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Membrane; Centrifugation, Density Gradient; Choline; Chromatography, Thin Layer; Culture Techniques; Cytoplasm; Dactinomycin; Encephalomyocarditis virus; Guanine Nucleotides; Lipids; Liver Neoplasms; Microscopy, Electron; Phosphatidylcholines; Puromycin; Rats; RNA Nucleotidyltransferases; RNA, Viral; Sucrose; Time Factors; Tritium; Uridine; Virus Replication

1970
The induction of hepatic cholesterol synthesis in the rat by lecithin mesophase infusions.
    The Journal of biological chemistry, 1974, Sep-25, Volume: 249, Issue:18

    Topics: Acetates; Alcohol Oxidoreductases; Animals; Carbon Dioxide; Carbon Radioisotopes; Cholesterol; Coenzyme A; Cycloheximide; Dactinomycin; Eggs; Injections, Intravenous; Liver; Male; Mevalonic Acid; Microsomes, Liver; Phosphatidylcholines; Phospholipids; Rats; Surface Properties

1974
Induction of choline phosphotransferase and lecithin synthesis in the fetal lung by corticosteroids.
    Science (New York, N.Y.), 1973, Jan-19, Volume: 179, Issue:4070

    Topics: Animals; Carbon Isotopes; Choline; Cycloheximide; Dactinomycin; Enzyme Induction; Female; Fetus; Gestational Age; In Vitro Techniques; Lung; Methionine; Phosphatidylcholines; Phosphotransferases; Prednisolone; Pregnancy; Rabbits

1973
Drug entrapment in liposomes.
    FEBS letters, 1973, Nov-01, Volume: 36, Issue:3

    Topics: Amines; Animals; Carbon Radioisotopes; Cholesterol; Dactinomycin; Intestine, Small; Kidney; Kinetics; Liposomes; Liver; Male; Penicillin G; Phosphatidylcholines; Phospholipids; Rats; Spleen; Tritium

1973
Relation between the hepatic action of drugs and the synthesis of subcellular structures.
    International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 9, Issue:1

    Topics: Aminopyrine N-Demethylase; Analysis of Variance; Animals; Choline; Dactinomycin; Deficiency Diseases; Diet; Drug Interactions; In Vitro Techniques; Liver; Male; Methionine; Methylation; Methyltransferases; Microsomes, Liver; Phenobarbital; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Biosynthesis; Rats; S-Adenosylmethionine; Subcellular Fractions

1974
Inhibition of 3-sn-phosphatidylcholine biosynthesis in baby-hamster kidney-21 cells infected with Semliki Forest virus.
    European journal of biochemistry, 1974, Apr-01, Volume: 43, Issue:2

    Topics: Animals; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Choline; Chromatography, Thin Layer; Cricetinae; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Endoplasmic Reticulum; Glycerides; Kidney; Kinetics; Microsomes; Phosphatidylcholines; Phosphotransferases; Semliki forest virus; Time Factors; Tritium; Viral Plaque Assay

1974
The effect of phytohemagglutinin on the activity of PC-cytidyl transferase and PC-glyceride transferase in cultured porcine lymphocytes.
    Canadian journal of biochemistry, 1972, Volume: 50, Issue:1

    Topics: Animals; Carbon Isotopes; Cells, Cultured; Choline; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Glycerides; Kinetics; Lectins; Leucine; Lipids; Lymph Nodes; Lymphocytes; Nucleotidyltransferases; Phosphatidylcholines; Phosphoric Acids; Phosphotransferases; Protein Biosynthesis; RNA; Swine; Tritium; Uridine

1972
Phospholipid synthesis in Sindbis virus-infected cells.
    Journal of virology, 1970, Volume: 6, Issue:5

    Topics: Animals; Arboviruses; Cell Line; Chick Embryo; Choline; Chromatography, Paper; Cricetinae; Culture Techniques; Cycloheximide; Dactinomycin; Fibroblasts; Kidney; Leucine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorus Isotopes; Protein Biosynthesis; RNA; RNA, Viral; Sphingomyelins; Time Factors; Tritium

1970
Tumor cell lipid composition and sensitivity to humoral immune killing. I. Modification of cellular lipid and fatty acid content by metabolic inhibitors and hormones.
    Journal of immunology (Baltimore, Md. : 1950), 1980, Volume: 124, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cardiolipins; Cattle; Cholesterol; Cytotoxicity, Immunologic; Dactinomycin; Doxorubicin; Fatty Acids; Fluorouracil; Guinea Pigs; Insulin; Lipids; Liver Neoplasms; Lysophosphatidylcholines; Phosphatidylcholines

1980
Liposome uptake into human colon adenocarcinoma cells in monolayer, spinner, and trypsinized cultures.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1983, Volume: 172, Issue:1

    Topics: Adenocarcinoma; Biological Transport; Cell Line; Colonic Neoplasms; Dactinomycin; DNA Replication; Humans; Kinetics; Lipid Bilayers; Phosphatidylcholines; Protein Biosynthesis; Transcription, Genetic; Trypsin

1983
The fate of liposome-entrapped actinomycin D in vivo and its therapeutic effect in a solid murine tumour [proceedings].
    Biochemical Society transactions, 1980, Volume: 8, Issue:1

    Topics: Animals; Dactinomycin; Drug Stability; Kinetics; Liposomes; Mice; Osteosarcoma; Phosphatidylcholines; Sarcoma, Experimental

1980
Increased synthesis and secretion of a 14-kDa phospholipase A2 by guinea pig alveolar macrophages. Dissociation from arachidonic acid liberation and modulation by dexamethasone.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Nov-15, Volume: 151, Issue:10

    Topics: Animals; Arachidonic Acid; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Guinea Pigs; Hydrogen-Ion Concentration; Leukotriene B4; Macrophages, Alveolar; Male; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Thromboxane B2

1993
Regulation of hepatic lecithin: retinol acyltransferase activity by retinoic acid.
    Archives of biochemistry and biophysics, 1993, Volume: 301, Issue:2

    Topics: Acyltransferases; Animals; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Esterification; Female; Liver; Male; Microsomes, Liver; Phosphatidylcholines; Protein Biosynthesis; Rats; Rats, Inbred Lew; Transcription, Genetic; Tretinoin; Vitamin A; Vitamin A Deficiency

1993
STUDIES ON THE ELECTRON TRANSFER SYSTEM. LVI. ON THE FORMATION OF AN ACTIVE COMPLEX BETWEEN THE APO-D(--)-BETA-HYDROXYBUTYRIC DEHYDROGENASE AND MICELLAR LECITHIN.
    The Journal of biological chemistry, 1963, Volume: 238

    Topics: Adenine; Anti-Bacterial Agents; Apolipoproteins D; Arsenic; Cadmium; Cell Respiration; Cysteine; Dactinomycin; Dicumarol; Dinitrophenols; Electron Transport; Electrons; Enzyme Inhibitors; Hydroxybutyrates; Ketones; Lecithins; NAD; Oxidoreductases; Phosphatidylcholines; Research; Tyrothricin

1963
Modified epidermal growth factor receptor (EGFR)-bearing liposomes (MRBLs) are sensitive to EGF in solution.
    PloS one, 2009, Oct-09, Volume: 4, Issue:10

    Topics: Animals; Benzoates; Chickens; Cross-Linking Reagents; Dactinomycin; Dimerization; Drug Delivery Systems; Epidermal Growth Factor; ErbB Receptors; Humans; Liposomes; Models, Biological; Ovum; Permeability; Phosphatidylcholines

2009
Hepatic toxicity following actinomycin D chemotherapy in treatment of familial gestational trophoblastic neoplasia: A case report.
    Medicine, 2018, Volume: 97, Issue:38

    Topics: Adaptor Proteins, Signal Transducing; Administration, Intravenous; Antibiotics, Antineoplastic; Asian People; Chemical and Drug Induced Liver Injury; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Drug-Related Side Effects and Adverse Reactions; Female; Gestational Trophoblastic Disease; Humans; Hypolipidemic Agents; Liver; Lung Neoplasms; Mutation; Neoplasm Staging; Phosphatidylcholines; Pregnancy; Proteins; Saponins; Tomography, X-Ray Computed; Treatment Outcome; Triterpenes; Young Adult

2018