Page last updated: 2024-09-05

phosphatidylcholines and d 609

phosphatidylcholines has been researched along with d 609 in 40 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(d 609)
Trials
(d 609)
Recent Studies (post-2010) (d 609)
32,2044435,593270048

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.50)18.7374
1990's17 (42.50)18.2507
2000's19 (47.50)29.6817
2010's3 (7.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Müller-Decker, K1
Halstead, J; Ignotz, RA; Kemp, K1
Crilly, KS; Kiss, Z1
Adam, D; Krämer, B; Krönke, M; Machleidt, T; Neumann, B; Schütze, S; Wiegmann, K1
Cowen, DS; Manning, DR; Sowers, RS1
Assmann, G; Gerdes, U; Höbbel, G; Nofer, JR; Reinecke, H; Seedorf, U; Walter, M1
Kostellow, AB; Ma, GY; Morrill, GA1
Amtmann, E1
de Widt, J; Hilkmann, H; Muriana, FJ; van Blitterswijk, WJ; van Dijk, MC1
Bertovich, M; Farber, JL; Koprowski, H; Michaels, FH; Moehren, G; Spitsin, SV1
King, GF; King, NJ; Roberts, NJ; Veale, MF1
Assmann, G; Nofer, JR; Seedorf, U; Tepel, M; Walter, M; Zidek, W1
Meisner, M; Schmidt, J; Tschaikowsky, K1
Hannun, YA; Luberto, C1
Johnson, RM; Kahle, PJ; Shooter, EM; Verity, AN1
Mookerjea, S; Ratnam, S1
Bettaïeb, A; Jaffrézou, JP; Laurent, G; Levade, T; Mansat-De Mas, V; Plo, I; Quillet-Mary, A1
Nakahata, N; Ohizumi, Y; Takano, H2
Honeyman, T; Ignotz, RA1
Kunnel, JG; Radeff, JM; Singh, AT; Stern, PH1
Dong, Z; Zhang, F; Zhao, G1
Antony, P; Farooqui, AA; Freysz, L; Horrocks, LA1
Forman, HJ; Girón-Calle, J; Srivatsa, K1
Ito, J; Nagayasu, Y; Ueno, S; Yokoyama, S1
Bezombes, C; Demur, C; Filomenko, R; Hernandez, H; Jaffrézou, JP; Laurent, G; Maestre, N; Mas, VM; Plo, I; Quillet-Mary, A1
Han, JS; Jung, PJ; Kim, JH; Kim, SC; Kim, SW; Yon, C1
Ishikawa, T; Ito, Y; Kondo, M; Kume, H; Nakayama, S; Sato, S; Shimokata, K; Son, M1
Garcia-Trinidad, A; Keegan, AD; Qu, CK; Rivas, MD; Zamorano, J1
Peiser, M; Wanner, R; Wittig, B1
Cornell, RB; Kitos, TE; Ng, MN1
Alava, MA; Anel, A; Barrio, G; Iturralde, M; Lacasa, E; Naval, J; Pardo, J; Piñeiro, A1
Bonventre, JV; Chin, MR; Jeon, HJ; Jeong, JY; Jung, KM; Jung, SY; Kang, MS; Kim, DK; Moon, CK; Seo, JH1
Araki, S; Cheng, Y; Liu, X; Miao, J; Zhang, S; Zhao, Q1
Adibhatla, RM; Hatcher, JF; Larsen, EC1
Kim, KW; Lehner, R; Minahk, C; Nelson, R; Trigatti, B; Vance, DE1
Bancells, C; Benítez, S; Jorba, O; Ordóñez-Llanos, J; Sánchez-Quesada, JL; Villegas, S1
Chung, R; Cowan, R; Fisher, RD; Fonteh, AN; Harrington, MG; Pogoda, JM; Sharma, TL1
Ajmat, MT; Bonilla, F; Bühler, MI; Minahk, C; Toranzo, GS1
Babica, P; Böke, H; Kumar, E; Park, JS; Sovadinova, I; Trosko, JE; Upham, BL; Wilke, A1

Other Studies

40 other study(ies) available for phosphatidylcholines and d 609

ArticleYear
Interruption of TPA-induced signals by an antiviral and antitumoral xanthate compound: inhibition of a phospholipase C-type reaction.
    Biochemical and biophysical research communications, 1989, Jul-14, Volume: 162, Issue:1

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Bridged-Ring Compounds; Cell Line; Cricetinae; Diglycerides; Fibroblasts; Humans; Norbornanes; Phosphatidylcholines; Phospholipids; Signal Transduction; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Tumor Cells, Cultured; Type C Phospholipases

1989
Evidence for involvement of phosphatidylcholine-phospholipase C and protein kinase C in transforming growth factor-beta signaling.
    The Journal of biological chemistry, 1995, Jun-09, Volume: 270, Issue:23

    Topics: Alkaloids; Bridged-Ring Compounds; GTP-Binding Proteins; Humans; Norbornanes; Phosphatidylcholines; Plasminogen Activator Inhibitor 1; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Transforming Growth Factor beta; Tumor Cells, Cultured; Type C Phospholipases

1995
Ethanolamine analogues stimulate DNA synthesis by a mechanism not involving phosphatidylethanolamine synthesis.
    FEBS letters, 1996, Feb-26, Volume: 381, Issue:1-2

    Topics: 3T3 Cells; Animals; Bridged-Ring Compounds; Clone Cells; Deanol; DNA; Dose-Response Relationship, Drug; Drug Synergism; Ethanolamines; Insulin; Kinetics; Mice; Norbornanes; Phosphatidylcholines; Phosphatidylethanolamines; Phosphodiesterase Inhibitors; Thiocarbamates; Thiones; Thymidine

1996
Function of the p55 tumor necrosis factor receptor "death domain" mediated by phosphatidylcholine-specific phospholipase C.
    The Journal of experimental medicine, 1996, Aug-01, Volume: 184, Issue:2

    Topics: Animals; Antigens, CD; Bridged-Ring Compounds; Cell Line; Enterotoxins; Enzyme Activation; Mice; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Phospholipases A; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Shock, Septic; Signal Transduction; Thiocarbamates; Thiones; Type C Phospholipases

1996
Activation of a mitogen-activated protein kinase (ERK2) by the 5-hydroxytryptamine1A receptor is sensitive not only to inhibitors of phosphatidylinositol 3-kinase, but to an inhibitor of phosphatidylcholine hydrolysis.
    The Journal of biological chemistry, 1996, Sep-13, Volume: 271, Issue:37

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Androstadienes; Animals; Bridged-Ring Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrolysis; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Norbornanes; Pertussis Toxin; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Thiocarbamates; Thiones; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin

1996
Defective regulation of phosphatidylcholine-specific phospholipases C and D in a kindred with Tangier disease. Evidence for the involvement of phosphatidylcholine breakdown in HDL-mediated cholesterol efflux mechanisms.
    The Journal of clinical investigation, 1996, Nov-15, Volume: 98, Issue:10

    Topics: Apolipoprotein A-I; Bridged-Ring Compounds; Butanols; Cells, Cultured; Diglycerides; Endothelins; Female; Fibroblasts; GTP-Binding Proteins; Humans; Lipoproteins, HDL; Male; Middle Aged; Norbornanes; Pedigree; Phosphatidic Acids; Phosphatidylcholines; Phosphodiesterase Inhibitors; Phospholipase D; Propranolol; Signal Transduction; Tangier Disease; Thiocarbamates; Thiones; Type C Phospholipases

1996
Progesterone triggers the rapid activation of phospholipase D in the amphibian oocyte plasma membrane when initiating the G2/M transition.
    Biochimica et biophysica acta, 1996, Dec-13, Volume: 1304, Issue:3

    Topics: Animals; Bridged-Ring Compounds; Cell Cycle; Cell Membrane; Choline; Diacylglycerol Kinase; Diglycerides; Enzyme Activation; Estradiol; Norbornanes; Oocytes; Phosphatidate Phosphatase; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphodiesterase Inhibitors; Phospholipase D; Phosphorylcholine; Phosphotransferases (Alcohol Group Acceptor); Progesterone; Rana pipiens; Sphingomyelins; Thiocarbamates; Thiones; Transferases (Other Substituted Phosphate Groups)

1996
The antiviral, antitumoural xanthate D609 is a competitive inhibitor of phosphatidylcholine-specific phospholipase C.
    Drugs under experimental and clinical research, 1996, Volume: 22, Issue:6

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Binding, Competitive; Bridged-Ring Compounds; Cattle; Norbornanes; Phosphatidylcholines; Thiocarbamates; Thiones; Type C Phospholipases

1996
Involvement of phosphatidylcholine-specific phospholipase C in platelet-derived growth factor-induced activation of the mitogen-activated protein kinase pathway in Rat-1 fibroblasts.
    The Journal of biological chemistry, 1997, Apr-25, Volume: 272, Issue:17

    Topics: Animals; Bridged-Ring Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Diglycerides; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Hydrolysis; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Phospholipase D; Platelet-Derived Growth Factor; Rats; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Thiocarbamates; Thiones; Type C Phospholipases

1997
Human- and mouse-inducible nitric oxide synthase promoters require activation of phosphatidylcholine-specific phospholipase C and NF-kappa B.
    Molecular medicine (Cambridge, Mass.), 1997, Volume: 3, Issue:5

    Topics: Animals; Antioxidants; Blotting, Western; Bridged-Ring Compounds; Cell Line; Cytokines; Epithelium; Gene Expression; Humans; Lipid Metabolism; Lung; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Ribonucleases; RNA-Binding Proteins; RNA, Messenger; Thiocarbamates; Thiones; Transcriptional Activation; Type C Phospholipases

1997
The generation of 1H-NMR-detectable mobile lipid in stimulated lymphocytes: relationship to cellular activation, the cell cycle, and phosphatidylcholine-specific phospholipase C.
    Biochemical and biophysical research communications, 1997, Oct-29, Volume: 239, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Bridged-Ring Compounds; CD3 Complex; Cell Cycle; Cell Division; Cell Survival; Drug Combinations; Ionomycin; Lipid Metabolism; Lipids; Lymphocyte Activation; Lymphocytes; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Norbornanes; Phosphatidylcholines; Receptors, Interleukin-2; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Thymus Gland; Type C Phospholipases; Up-Regulation

1997
Phosphatidylcholine-specific phospholipase C regulates thapsigargin-induced calcium influx in human lymphocytes.
    The Journal of biological chemistry, 1997, Dec-26, Volume: 272, Issue:52

    Topics: Bridged-Ring Compounds; Butanols; Calcium; Enzyme Inhibitors; Estrenes; Humans; Indoles; Lymphocytes; Nickel; Norbornanes; Phosphatidylcholines; Phosphatidylinositols; Propranolol; Pyrrolidinones; Tetradecanoylphorbol Acetate; Thapsigargin; Thiocarbamates; Thiones; Type C Phospholipases

1997
Modulation of mouse endotoxin shock by inhibition of phosphatidylcholine-specific phospholipase C.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:2

    Topics: Animals; Bridged-Ring Compounds; Female; Interleukin-1; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Shock, Septic; Thiocarbamates; Thiones; Tumor Necrosis Factor-alpha; Type C Phospholipases

1998
Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?
    The Journal of biological chemistry, 1998, Jun-05, Volume: 273, Issue:23

    Topics: Bridged-Ring Compounds; Cell Line; Cell Membrane; Ceramides; Diglycerides; Enzyme Inhibitors; Humans; Lung; Molecular Structure; Norbornanes; Phosphatidylcholines; Simian virus 40; Sphingomyelin Phosphodiesterase; Sphingomyelins; Thiocarbamates; Thiones; Transferases (Other Substituted Phosphate Groups); Transformation, Genetic; Type C Phospholipases

1998
Phosphatidylcholine-specific phospholipase inhibitor D609 differentially affects MAP kinases and immediate-early genes in PC12 cells.
    Cellular signalling, 1998, Volume: 10, Issue:5

    Topics: Animals; Bridged-Ring Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation; Genes, Immediate-Early; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norbornanes; PC12 Cells; Phosphatidylcholines; Phospholipases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Thiocarbamates; Thiones

1998
The regulation of superoxide generation and nitric oxide synthesis by C-reactive protein.
    Immunology, 1998, Volume: 94, Issue:4

    Topics: Animals; Blotting, Western; Bridged-Ring Compounds; C-Reactive Protein; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Macrophages, Peritoneal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Time Factors

1998
Daunorubicin- and mitoxantrone-triggered phosphatidylcholine hydrolysis: implication in drug-induced ceramide generation and apoptosis.
    Molecular pharmacology, 1999, Volume: 55, Issue:1

    Topics: Apoptosis; Bridged-Ring Compounds; Ceramides; Daunorubicin; Diglycerides; DNA Fragmentation; Humans; Hydrolysis; Mitoxantrone; Norbornanes; Phosphatidylcholines; Protein Kinase C; Thiocarbamates; Thiones; Tumor Cells, Cultured

1999
Thromboxane A2-induced phosphatidylcholine hydrolysis in porcine vascular smooth muscle cells.
    European journal of pharmacology, 1999, Jun-11, Volume: 374, Issue:1

    Topics: Animals; Bridged-Ring Compounds; Cells, Cultured; Diglycerides; Glycerophospholipids; Hydrolysis; Muscle, Smooth, Vascular; Norbornanes; Phosphatidylcholines; Receptors, Thromboxane; Swine; Thiocarbamates; Thiones; Thromboxane A2

1999
Thromboxane A2 receptor-mediated tonic contraction is attributed to an activation of phosphatidylcholine-specific phospholipase C in rabbit aortic smooth muscles.
    Life sciences, 2000, Volume: 66, Issue:5

    Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cells, Cultured; Enzyme Activation; Fatty Acids, Unsaturated; Female; Hydrazines; Inhibitory Concentration 50; Isotonic Contraction; Male; Muscle, Smooth, Vascular; Norbornanes; Norepinephrine; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phosphorylcholine; Rabbits; Receptors, Thromboxane; Signal Transduction; Thiocarbamates; Thiones; Thromboxane A2; Type C Phospholipases

2000
TGF-beta signaling in A549 lung carcinoma cells: lipid second messengers.
    Journal of cellular biochemistry, 2000, Jun-12, Volume: 78, Issue:4

    Topics: Acetophenones; Arachidonic Acid; Bridged-Ring Compounds; Calcium; Chelating Agents; Chromatography, Thin Layer; Diglycerides; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix; Humans; Hydrolysis; Lipids; Lung Neoplasms; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Plasmids; Protein Isoforms; Second Messenger Systems; Sphingosine; Thiocarbamates; Thiones; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured; Type C Phospholipases

2000
Phosphatidylcholine-specific phospholipase C inhibitor, tricyclodecan-9-yl xanthogenate (D609), increases phospholipase D-mediated phosphatidylcholine hydrolysis in UMR-106 osteoblastic osteosarcoma cells.
    Biochimica et biophysica acta, 2000, Sep-27, Volume: 1487, Issue:2-3

    Topics: Antineoplastic Agents; Bone Neoplasms; Bridged-Ring Compounds; Choline; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Humans; Hydrolysis; Isoenzymes; Norbornanes; Osteosarcoma; Parathyroid Hormone; Phosphatidylcholines; Signal Transduction; Temperature; Thiocarbamates; Thiones; Tritium; Tumor Cells, Cultured; Type C Phospholipases

2000
Phosphatidylcholine-specific phospholipase C and D in stimulation of RAW264.7 mouse macrophage-like cells by lipopolysaccharide.
    International immunopharmacology, 2001, Volume: 1, Issue:7

    Topics: Adrenergic beta-Antagonists; Amino Acid Sequence; Animals; Blotting, Northern; Blotting, Western; Bridged-Ring Compounds; Butanols; Cell Line; Enzyme Inhibitors; Indicators and Reagents; Lipid Metabolism; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Norbornanes; Phosphatidylcholines; Phospholipase D; Propranolol; RNA, Messenger; Thiocarbamates; Thiones; Tumor Necrosis Factor-alpha; Type C Phospholipases

2001
Effect of D609 on phosphatidylcholine metabolism in the nuclei of LA-N-1 neuroblastoma cells: a key role for diacylglycerol.
    FEBS letters, 2001, Nov-30, Volume: 509, Issue:1

    Topics: Antioxidants; Bridged-Ring Compounds; Cell Division; Cell Nucleus; Choline-Phosphate Cytidylyltransferase; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrolysis; Lipid Metabolism; Neuroblastoma; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Thiocarbamates; Thiones; Time Factors; Tumor Cells, Cultured; Type C Phospholipases

2001
Priming of alveolar macrophage respiratory burst by H(2)O(2) is prevented by phosphatidylcholine-specific phospholipase C inhibitor Tricyclodecan-9-yl-xanthate (D609).
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:1

    Topics: Animals; Antioxidants; Bridged-Ring Compounds; Cells, Cultured; Cytochrome c Group; Hydrogen Peroxide; Indicators and Reagents; Macrophages, Alveolar; Norbornanes; Oxidants; Phosphatidylcholines; Phosphodiesterase Inhibitors; Rats; Respiratory Burst; Thiocarbamates; Thiones; Type C Phospholipases

2002
Apolipoprotein-mediated cellular lipid release requires replenishment of sphingomyelin in a phosphatidylcholine-specific phospholipase C-dependent manner.
    The Journal of biological chemistry, 2002, Nov-22, Volume: 277, Issue:47

    Topics: Acetates; Animals; Apolipoprotein A-I; Astrocytes; Bridged-Ring Compounds; Cell Line; Cells, Cultured; Ceramides; Cholesterol; Diglycerides; Glycerol; Humans; Mice; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Signal Transduction; Sphingomyelin Phosphodiesterase; Sphingomyelins; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Type C Phospholipases

2002
Protein kinase Czeta mediated Raf-1/extracellular-regulated kinase activation by daunorubicin.
    Blood, 2003, Feb-15, Volume: 101, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antioxidants; Bridged-Ring Compounds; Cell Death; Daunorubicin; Diglycerides; Enzyme Activation; Flavonoids; Humans; Leukemia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norbornanes; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-raf; Reactive Oxygen Species; Thiocarbamates; Thiones; Transfection; Tumor Cells, Cultured; Wortmannin

2003
Phosphatidylcholine-specific phospholipase C and RhoA are involved in the thyrotropin-induced activation of phospholipase D in FRTL-5 thyroid cells.
    Molecules and cells, 2002, Oct-31, Volume: 14, Issue:2

    Topics: ADP Ribose Transferases; Animals; Botulinum Toxins; Bridged-Ring Compounds; Cell Line; Diglycerides; Norbornanes; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Rats; rhoA GTP-Binding Protein; Thiocarbamates; Thiones; Thyroid Gland; Thyrotropin; Type C Phospholipases

2002
Apical and basolateral ATP-induced anion secretion in polarized human airway epithelia.
    American journal of respiratory cell and molecular biology, 2004, Volume: 30, Issue:3

    Topics: Adenine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Bridged-Ring Compounds; Calcium; Cell Polarity; Charybdotoxin; Chloride Channels; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophysiology; Enzyme Inhibitors; Epithelial Cells; Humans; Lung; Norbornanes; Phosphatidylcholines; Phosphatidylinositols; Phospholipid Ethers; Potassium; Potassium Channels, Calcium-Activated; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thiocarbamates; Thiones; Type C Phospholipases

2004
Phosphatidylcholine-specific phospholipase C activity is necessary for the activation of STAT6.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Oct-15, Volume: 171, Issue:8

    Topics: Animals; Bridged-Ring Compounds; Cell Line; Cell Line, Tumor; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; Interleukin-4; Janus Kinase 1; Janus Kinase 3; Mice; Norbornanes; Phosphatidylcholines; Protein-Tyrosine Kinases; Signal Transduction; STAT6 Transcription Factor; Substrate Specificity; Thiocarbamates; Thiones; Trans-Activators; Type C Phospholipases; Vanadium Compounds

2003
Keratinocytes rapidly readjust ceramide-sphingomyelin homeostasis and contain a phosphatidylcholine-sphingomyelin transacylase.
    The Journal of investigative dermatology, 2004, Volume: 122, Issue:3

    Topics: Bridged-Ring Compounds; Cells, Cultured; Ceramides; Fluorescence; Homeostasis; Keratinocytes; Norbornanes; Phosphatidylcholines; Sphingomyelins; Thiocarbamates; Thiones; Transaldolase

2004
Contribution of lipid second messengers to the regulation of phosphatidylcholine synthesis during cell cycle re-entry.
    Biochimica et biophysica acta, 2004, Nov-08, Volume: 1686, Issue:1-2

    Topics: Animals; Arachidonic Acid; Bridged-Ring Compounds; Butanols; Cattle; Cell Cycle; Cell Line; Choline; Choline-Phosphate Cytidylyltransferase; Cricetinae; Cricetulus; Diglycerides; Enzyme Inhibitors; Fatty Acids; Fibroblasts; G1 Phase; Glycerophospholipids; Group VI Phospholipases A2; Humans; Naphthalenes; Norbornanes; Phosphatidic Acids; Phosphatidylcholines; Phospholipases A; Pyrones; Resting Phase, Cell Cycle; Second Messenger Systems; Serum Albumin, Bovine; Thiocarbamates; Thiones; Type C Phospholipases

2004
Characterization of the lipolytic pathways that mediate free fatty acid release during Fas/CD95-induced apoptosis.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:6

    Topics: Apoptosis; Arachidonic Acids; Bridged-Ring Compounds; Cyclohexanones; Endocannabinoids; Enzyme Inhibitors; fas Receptor; Fatty Acids, Nonesterified; Glycerides; Humans; Jurkat Cells; Ketones; Lipid Metabolism; Lipolysis; Lipoprotein Lipase; Models, Biological; Norbornanes; Palmitic Acid; Phosphatidic Acids; Phosphatidylcholines; Thiocarbamates; Thiones; Type C Phospholipases

2005
Methylmercury-induced toxicity is mediated by enhanced intracellular calcium through activation of phosphatidylcholine-specific phospholipase C.
    Toxicology and applied pharmacology, 2006, Oct-15, Volume: 216, Issue:2

    Topics: Animals; Bridged-Ring Compounds; Calcium; Cell Line, Tumor; Cell Survival; Chelating Agents; Diglycerides; Dogs; Dose-Response Relationship, Drug; Egtazic Acid; Environmental Pollutants; Enzyme Activation; Humans; Kidney; Methylmercury Compounds; Neuroblastoma; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Phospholipases A; Reactive Oxygen Species; Sphingomyelin Phosphodiesterase; Thiocarbamates; Thiones; Type C Phospholipases

2006
Phosphatidylcholine-specific phospholipase C, p53 and ROS in the association of apoptosis and senescence in vascular endothelial cells.
    FEBS letters, 2006, Sep-04, Volume: 580, Issue:20

    Topics: Animals; Apoptosis; Bridged-Ring Compounds; Cell Shape; Cells, Cultured; Cellular Senescence; Crotalid Venoms; Endothelial Cells; Humans; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Reactive Oxygen Species; Thiocarbamates; Thiones; Tumor Suppressor Protein p53; Type C Phospholipases

2006
Effect of tricyclodecan-9-yl potassium xanthate (D609) on phospholipid metabolism and cell death during oxygen-glucose deprivation in PC12 cells.
    Neuroscience, 2007, May-25, Volume: 146, Issue:3

    Topics: Animals; Annexin A5; Bridged-Ring Compounds; Calcium; Cell Death; Cell Hypoxia; Cell Survival; Ceramides; Culture Media; Cytochromes c; Diglycerides; Fatty Acids, Nonesterified; Glucose; Glutathione; L-Lactate Dehydrogenase; Mitochondria; Norbornanes; PC12 Cells; Phosphatidylcholines; Phospholipids; Poly(ADP-ribose) Polymerases; Rats; Sphingomyelin Phosphodiesterase; Sphingomyelins; Thiocarbamates; Thiones; Trypan Blue

2007
Conversion of low density lipoprotein-associated phosphatidylcholine to triacylglycerol by primary hepatocytes.
    The Journal of biological chemistry, 2008, Mar-07, Volume: 283, Issue:10

    Topics: Acylation; Animals; Apolipoprotein B-100; Bridged-Ring Compounds; Cell Line; Cholesterol Esters; Cholesterol, LDL; Crotalid Venoms; Diacylglycerol O-Acyltransferase; Enzyme Activation; Hepatocytes; Liver; Lysosomes; Mice; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Receptors, LDL; Scavenger Receptors, Class B; Thiocarbamates; Thiones; Triglycerides; Type C Phospholipases

2008
Novel phospholipolytic activities associated with electronegative low-density lipoprotein are involved in increased self-aggregation.
    Biochemistry, 2008, Aug-05, Volume: 47, Issue:31

    Topics: Anion Exchange Resins; Apolipoprotein C-III; Apolipoproteins E; Bridged-Ring Compounds; Chromatography, Ion Exchange; Enzyme Activation; Hydrogen-Ion Concentration; Lipolysis; Lipoproteins, LDL; Lysophosphatidylcholines; Magnesium; Norbornanes; Phosphatidylcholines; Phosphodiesterase Inhibitors; Phospholipids; Sphingomyelins; Sulfones; Thiocarbamates; Thiones; Time Factors

2008
Cerebrospinal fluid phospholipase C activity increases in migraine.
    Cephalalgia : an international journal of headache, 2011, Volume: 31, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bridged-Ring Compounds; Enzyme Activation; Female; Humans; Male; Middle Aged; Migraine Disorders; Norbornanes; Phosphatidylcholines; Thiocarbamates; Thiones; Type C Phospholipases

2011
Identification of phospholipase activity in Rhinella arenarum sperm extract capable of inducing oocyte activation.
    Zygote (Cambridge, England), 2014, Volume: 22, Issue:4

    Topics: 1-Butanol; Animals; Bridged-Ring Compounds; Bufo arenarum; Chromatography, Gel; Female; In Vitro Oocyte Maturation Techniques; Male; Microinjections; Neomycin; Norbornanes; Oocytes; Phosphatidylcholines; Phospholipases; Protein Kinase C; Sperm Head; Sperm-Ovum Interactions; Spermatozoa; Thiocarbamates; Thiones; Type C Phospholipases

2014
Phosphatidylcholine Specific PLC-Induced Dysregulation of Gap Junctions, a Robust Cellular Response to Environmental Toxicants, and Prevention by Resveratrol in a Rat Liver Cell Model.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Bridged-Ring Compounds; Butadienes; Cell Line; Gap Junctions; Nitriles; Norbornanes; Phosphatidylcholines; Principal Component Analysis; Rats; Rats, Inbred F344; Resveratrol; Stilbenes; Thiocarbamates; Thiones; Type C Phospholipases

2015