Page last updated: 2024-09-05

phosphatidylcholines and cytarabine

phosphatidylcholines has been researched along with cytarabine in 10 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(cytarabine)
Trials
(cytarabine)
Recent Studies (post-2010) (cytarabine)
32,2044435,59315,4872,4243,188

Protein Interaction Comparison

ProteinTaxonomyphosphatidylcholines (IC50)cytarabine (IC50)
nuclear receptor coactivator 3 isoform aHomo sapiens (human)7.533
E3 ubiquitin-protein ligase Mdm2Homo sapiens (human)0.02

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's3 (30.00)18.2507
2000's0 (0.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dave, C; Mayhew, E; Papahadjopoulos, D; Rustum, YM1
Carpen, M; Cohen, JS; Daly, PF; Myers, CE; Sandler, D; Zugmaier, G1
Alkan, H; Son, K1
Green, AM; King, J; Lazo, R; Mayhew, E; Vail, WJ1
Steim, JM; Turcotte, JG; Yang, VC1
Ganapathi, R; Krishan, A; Lesko, LJ; Wodinsky, I; Zubrod, CG1
Huang, L; Kennel, SJ; Mori, A1
Berkovic, D; Breass, J; Fleer, EA; Hiddemann, W; Pförtner, J; Schleyer, E1
Chen, C; Han, D; Tang, X; Yuan, Y; Zhang, Y1
Jalili, S; Karami, L1

Other Studies

10 other study(ies) available for phosphatidylcholines and cytarabine

ArticleYear
Use of liposomes for the enhancement of the cytotoxic effects of cytosine arabinoside.
    Annals of the New York Academy of Sciences, 1978, Volume: 308

    Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cytarabine; Drug Synergism; Female; Leukemia L1210; Liposomes; Mice; Mice, Inbred DBA; Pharmaceutical Vehicles; Phosphatidylcholines; Phosphatidylserines; Pregnancy; Tissue Distribution

1978
Regulation of the cytidine phospholipid pathways in human cancer cells and effects of 1-beta-D-arabinofuranosylcytosine: a noninvasive 31P nuclear magnetic resonance study.
    Cancer research, 1990, Feb-01, Volume: 50, Issue:3

    Topics: Basement Membrane; Breast Neoplasms; Cytarabine; Humans; In Vitro Techniques; Lymphoma; Magnetic Resonance Spectroscopy; Nucleotidyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Phosphoric Diester Hydrolases; Tumor Cells, Cultured

1990
Liposomes prepared dynamically by interactions between bile salt and phospholipid molecules.
    Biochimica et biophysica acta, 1989, Jun-06, Volume: 981, Issue:2

    Topics: Bile Acids and Salts; Blood; Chemical Phenomena; Chemistry, Physical; Cytarabine; Humans; In Vitro Techniques; Light; Liposomes; Micelles; Microscopy, Electron; Phosphatidylcholines; Scattering, Radiation

1989
Characterization of liposomes prepared using a microemulsifier.
    Biochimica et biophysica acta, 1984, Aug-22, Volume: 775, Issue:2

    Topics: Biochemistry; Cholesterol; Cytarabine; Emulsions; Freeze Fracturing; Liposomes; Methods; Microscopy, Electron; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Time Factors

1984
Physical properties of arabinofuranosylcytosine diphosphate diacylglycerol, an antitumor liponucleotide.
    Biochimica et biophysica acta, 1982, Jul-28, Volume: 689, Issue:2

    Topics: Chemical Phenomena; Chemistry; Cytarabine; Kinetics; Micelles; Molecular Conformation; Phosphatidylcholines; Temperature

1982
Effect of cholesterol content on antitumor activity and toxicity of liposome-encapsulated 1-beta-D-arabinofuranosylcytosine in vivo.
    Cancer research, 1980, Volume: 40, Issue:3

    Topics: Animals; Cholesterol; Cytarabine; Dose-Response Relationship, Drug; Leukemia L1210; Liposomes; Mice; Phosphatidylcholines

1980
Immunotargeting of liposomes containing lipophilic antitumor prodrugs.
    Pharmaceutical research, 1993, Volume: 10, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Binding Sites; Cholesterol; Cytarabine; Cytidine Diphosphate Diglycerides; Doxorubicin; Drug Carriers; Floxuridine; Gangliosides; Liposomes; Male; Mice; Mice, Inbred BALB C; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Prodrugs; Surface Properties

1993
The influence of 1-beta-D-arabinofuranosylcytosine on the metabolism of phosphatidylcholine in human leukemic HL 60 and Raji cells.
    Leukemia, 1997, Volume: 11, Issue:12

    Topics: Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Cell Survival; Cytarabine; HL-60 Cells; Humans; Lysophosphatidylcholines; Phosphatidylcholines

1997
The freeze-thawed and freeze-dried stability of cytarabine-encapsulated multivesicular liposomes.
    International journal of pharmaceutics, 2010, Mar-15, Volume: 387, Issue:1-2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Antimetabolites, Antineoplastic; Chemistry, Pharmaceutical; Cytarabine; Delayed-Action Preparations; Drug Stability; Emulsions; Freeze Drying; Freezing; Liposomes; Particle Size; Phosphatidylcholines

2010
Effects of cholesterol concentration on the interaction of cytarabine with lipid membranes: a molecular dynamics simulation study.
    Journal of biomolecular structure & dynamics, 2015, Volume: 33, Issue:6

    Topics: Cholesterol; Cytarabine; Hydrogen Bonding; Lipid Bilayers; Models, Molecular; Models, Theoretical; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines

2015