Page last updated: 2024-09-05

phosphatidylcholines and celecoxib

phosphatidylcholines has been researched along with celecoxib in 6 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(celecoxib)
Trials
(celecoxib)
Recent Studies (post-2010) (celecoxib)
32,2044435,5935,2738432,428

Protein Interaction Comparison

ProteinTaxonomyphosphatidylcholines (IC50)celecoxib (IC50)
Chain A, Carbonic anhydrase IIHomo sapiens (human)0.021
Prostaglandin E synthaseHomo sapiens (human)0.4825
Histone deacetylase 3Homo sapiens (human)1.637
Prostaglandin G/H synthase 1 Bos taurus (cattle)7.9667
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.057
Cytochrome c oxidase subunit 1Ovis aries (sheep)6.5
Cytochrome c oxidase subunit 2Ovis aries (sheep)0.0881
Catechol O-methyltransferaseMus musculus (house mouse)0.036
Cytochrome c oxidase subunit 2Homo sapiens (human)0.371
Carbonic anhydrase 1Homo sapiens (human)0.1555
Carbonic anhydrase 2Homo sapiens (human)0.0925
Prostaglandin G/H synthase 1Ovis aries (sheep)5.271
Procathepsin LHomo sapiens (human)0.56
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)7.308
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)0.07
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)4.295
Cytochrome P450 2D6Homo sapiens (human)1
Cytochrome P450 2C9 Homo sapiens (human)10
Calpain-2 catalytic subunitHomo sapiens (human)0.002
Alpha-2B adrenergic receptorHomo sapiens (human)1.516
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.12
Prostaglandin G/H synthase 1Mus musculus (house mouse)3.6401
Prostaglandin G/H synthase 1Homo sapiens (human)3.5499
Sodium-dependent noradrenaline transporter Homo sapiens (human)7.308
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.006
Sodium-dependent serotonin transporterHomo sapiens (human)6.276
Prostaglandin G/H synthase 2Homo sapiens (human)0.3818
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.4028
Urotensin-2 receptorRattus norvegicus (Norway rat)7.6
Histone deacetylase 4Homo sapiens (human)1.637
D(2) dopamine receptorRattus norvegicus (Norway rat)0.03
Prostaglandin G/H synthase 2Ovis aries (sheep)0.6343
Mu-type opioid receptorCavia porcellus (domestic guinea pig)7.7
Sodium-dependent dopamine transporter Homo sapiens (human)2.431
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.045
Histone deacetylase 1Homo sapiens (human)1.411
Mitogen-activated protein kinase 14Homo sapiens (human)0.81
Carbonic anhydrase 9Homo sapiens (human)0.016
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.05
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.3
Prostaglandin G/H synthase 1Canis lupus familiaris (dog)5.57
Cyclooxygenase-2 Canis lupus familiaris (dog)0.9
Histone deacetylase 7Homo sapiens (human)1.637
Histone deacetylase 2Homo sapiens (human)1.637
Carbonic anhydrase 4Bos taurus (cattle)0.2227
Polyamine deacetylase HDAC10Homo sapiens (human)1.637
Histone deacetylase 11 Homo sapiens (human)1.637
Histone deacetylase 8Homo sapiens (human)1.637
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.04
Histone deacetylase 6Homo sapiens (human)1.14
Histone deacetylase 9Homo sapiens (human)1.637
Histone deacetylase 5Homo sapiens (human)1.637

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dial, EJ; Lichtenberger, LM; Romero, JJ1
Banerjee, S; Sade, A; Severcan, F1
Danino, D; Kesselman, E; Magdassi, S; Margulis-Goshen, K1
Banerjee, S; Erdoğ, A; Keskin, D; Putra Limasale, YD; Tezcaner, A1
El-Badry, M; Fathalla, D; Fetih, G1
Bauer-Brandl, A; Brandl, M; Elvang, PA; Jacobsen, AC; Stein, PC1

Other Studies

6 other study(ies) available for phosphatidylcholines and celecoxib

ArticleYear
Surface phospholipids in gastric injury and protection when a selective cyclooxygenase-2 inhibitor (Coxib) is used in combination with aspirin.
    British journal of pharmacology, 2007, Volume: 150, Issue:7

    Topics: Animals; Aspirin; Celecoxib; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Gastric Mucosa; Hydrophobic and Hydrophilic Interactions; Male; Phosphatidylcholines; Pyrazoles; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sulfonamides

2007
Concentration-dependent differing actions of the nonsteroidal anti-inflammatory drug, celecoxib, in distearoyl phosphatidylcholine multilamellar vesicles.
    Journal of liposome research, 2010, Volume: 20, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Celecoxib; Drug Carriers; Drug Delivery Systems; Liposomes; Nephelometry and Turbidimetry; Phosphatidylcholines; Pyrazoles; Sulfonamides; Temperature

2010
Formation of celecoxib nanoparticles from volatile microemulsions.
    International journal of pharmaceutics, 2010, Jun-30, Volume: 393, Issue:1-2

    Topics: Acetates; Butanols; Celecoxib; Chemistry, Pharmaceutical; Cryoelectron Microscopy; Cyclooxygenase 2 Inhibitors; Drug Carriers; Drug Compounding; Electric Conductivity; Emulsions; Glycyrrhizic Acid; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Phosphatidylcholines; Powders; Pyrazoles; Solubility; Sulfonamides; Surface-Active Agents; Technology, Pharmaceutical; Volatilization; Water

2010
In vitro characterization of a liposomal formulation of celecoxib containing 1,2-distearoyl-sn-glycero-3-phosphocholine, cholesterol, and polyethylene glycol and its functional effects against colorectal cancer cell lines.
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:10

    Topics: Celecoxib; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Cholesterol; Colorectal Neoplasms; Drug Delivery Systems; HCT116 Cells; HT29 Cells; Humans; Liposomes; Phosphatidylcholines; Polyethylene Glycols; Pyrazoles; Sulfonamides

2013
Liposomal gels for site-specific, sustained delivery of celecoxib: in vitro and in vivo evaluation.
    Drug development research, 2014, Volume: 75, Issue:4

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Celecoxib; Cholesterol; Drug Compounding; Edema; Gels; Liposomes; Particle Size; Phosphatidylcholines; Pyrazoles; Rats; Rats, Wistar; Sulfonamides

2014
Co-existing colloidal phases in artificial intestinal fluids assessed by AF4/MALLS and DLS: A systematic study into cholate & (lyso-) phospholipid blends, incorporating celecoxib as a model drug.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Jul-30, Volume: 120

    Topics: Celecoxib; Colloids; Digestion; Drug Compounding; Dynamic Light Scattering; Fractionation, Field Flow; Glycodeoxycholic Acid; Intestinal Secretions; Lasers; Lysophosphatidylcholines; Micelles; Phosphatidylcholines; Scattering, Radiation; Solubility; Surface-Active Agents; Taurocholic Acid; Technology, Pharmaceutical

2018