Page last updated: 2024-09-05

phosphatidylcholines and camptothecin

phosphatidylcholines has been researched along with camptothecin in 18 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(camptothecin)
Trials
(camptothecin)
Recent Studies (post-2010) (camptothecin)
32,2044435,59313,0022,2295,391

Protein Interaction Comparison

ProteinTaxonomyphosphatidylcholines (IC50)camptothecin (IC50)
Histone deacetylase 3Homo sapiens (human)0.05
Multidrug resistance-associated protein 4Homo sapiens (human)7.4
DNA topoisomerase 1Homo sapiens (human)1.9799
Somatostatin receptor type 1Homo sapiens (human)0.0022
Somatostatin receptor type 2Homo sapiens (human)0.0022
Somatostatin receptor type 4Homo sapiens (human)0.0022
Somatostatin receptor type 3Homo sapiens (human)0.0022
Somatostatin receptor type 5Homo sapiens (human)0.0022
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.97
Histone deacetylase 4Homo sapiens (human)0.05
Histone deacetylase 1Homo sapiens (human)0.05
Histone deacetylase 7Homo sapiens (human)0.05
Histone deacetylase 2Homo sapiens (human)0.05
Polyamine deacetylase HDAC10Homo sapiens (human)0.05
Histone deacetylase 11 Homo sapiens (human)0.05
Histone deacetylase 8Homo sapiens (human)0.05
Histone deacetylase 6Homo sapiens (human)0.05
Histone deacetylase 9Homo sapiens (human)0.05
Histone deacetylase 5Homo sapiens (human)0.05

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (22.22)18.2507
2000's7 (38.89)29.6817
2010's6 (33.33)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Burke, TG; Gao, X1
Burke, TG; Mishra, AK; Wall, ME; Wani, MC1
Anthony, ML; Brindle, KM; Zhao, M1
Gilbert, BE; Knight, V; Koshkina, NV; Seryshev, A; Waldrep, JC1
Gilbert, BE; Giovanella, BC; Kleinerman, ES; Knight, V; Koshkina, NV; Waldrep, JC1
Ahmad, I; Parmar, M; Peikov, V; Ugwu, S; Zhang, A1
Fang, XL; Li, JC; Sha, XY; Zhang, LJ1
Chen, J; Chu, XZ; Guo, JX; Ping, QN; Song, MM1
Cabral-Lilly, D; Cafiso, DS; Cho, C; Dicko, A; Ellena, JF; Frazier, AA; Hinderliter, A; Liboiron, BD; Mayer, LD; Tardi, PG; Weber, T; Xie, X1
Gaud, R; Shende, P1
Atyabi, F; Dinarvand, R; Esmaeili, F; Farkhondehfai, A1
Anantha, M; Bally, M; Patankar, N; Ramsay, E; Waterhouse, D1
Li, P; Lin, Y; Ran, H; Ren, J; Tan, J; Wang, Z; Zhang, Q; Zheng, Y1
Anderson, BD; Modi, S; Xiang, TX1
Aljuffali, IA; Fang, JY; Huang, YJ; Sung, CT; Wen, CJ1
Anantha, M; Bally, MB; Harasym, N; Manisali, I; Masin, D; Osooly, M; Ostlund, C; Santos, ND; Strutt, D; Sutherland, BW; Waterhouse, DN; Webb, MS; Wehbe, M1
Du, Y; He, W; Li, X; Yao, C; Zhou, W1
Chakraborty, K; Hu, W; Kang, M; Loverde, SM; Tang, PK1

Other Studies

18 other study(ies) available for phosphatidylcholines and camptothecin

ArticleYear
Stabilization of topotecan in low pH liposomes composed of distearoylphosphatidylcholine.
    Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:7

    Topics: Antineoplastic Agents; Buffers; Camptothecin; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Drug Carriers; Drug Stability; Humans; Hydrogen-Ion Concentration; Lactones; Liposomes; Phosphatidylcholines; Topotecan

1994
Lipid bilayer partitioning and stability of camptothecin drugs.
    Biochemistry, 1993, May-25, Volume: 32, Issue:20

    Topics: Binding Sites; Camptothecin; Dimyristoylphosphatidylcholine; Drug Stability; Fluorescence Polarization; Hydrogen-Ion Concentration; Kinetics; Lipid Bilayers; Phosphatidylcholines; Phosphatidylglycerols; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship

1993
Inhibition of phosphatidylcholine biosynthesis following induction of apoptosis in HL-60 cells.
    The Journal of biological chemistry, 1999, Jul-09, Volume: 274, Issue:28

    Topics: Alkaloids; Apoptosis; Benzophenanthridines; Camptothecin; Choline; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Enzyme Inhibitors; Etoposide; Farnesol; Flow Cytometry; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Phenanthridines; Phosphatidylcholines; Phosphorylcholine

1999
Distribution of camptothecin after delivery as a liposome aerosol or following intramuscular injection in mice.
    Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:3

    Topics: Aerosols; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Carriers; Female; Humans; Injections, Intramuscular; Liposomes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Phosphatidylcholines

1999
9-Nitrocamptothecin liposome aerosol treatment of human cancer subcutaneous xenografts and pulmonary cancer metastases in mice.
    Annals of the New York Academy of Sciences, 2000, Volume: 922

    Topics: Aerosols; Animals; Antineoplastic Agents; Bone Neoplasms; Camptothecin; Colonic Neoplasms; Drug Carriers; Female; Humans; Liposomes; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Microscopy, Electron; Osteosarcoma; Particle Size; Phosphatidylcholines; Xenograft Model Antitumor Assays

2000
pH-dependent association of SN-38 with lipid bilayers of a novel liposomal formulation.
    International journal of pharmaceutics, 2005, Aug-11, Volume: 299, Issue:1-2

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cardiolipins; Cholesterol; Chromatography, Gel; Diphenylhexatriene; Fluorescence Polarization; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Irinotecan; Lipid Bilayers; Liposomes; Particle Size; Phosphatidylcholines; Temperature; Topoisomerase I Inhibitors

2005
[9-nitrocamptothecin nanostructured lipid carrier system: in vitro releasing characteristics, uptake by cells, and tissue distribution in vivo].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:11

    Topics: Animals; Antineoplastic Agents; Camptothecin; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Female; Hexoses; Liver; Lung; Macrophages, Peritoneal; Mice; Nanoparticles; Particle Size; Phagocytosis; Phosphatidylcholines; Polyethylene Glycols; Tissue Distribution

2005
Effect of phospholipid composition on characterization of liposomes containing 9-nitrocamptothecin.
    Drug development and industrial pharmacy, 2006, Volume: 32, Issue:6

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cholesterol; Drug Compounding; Feasibility Studies; Glycine max; Hydrogenation; Injections, Intravenous; Liposomes; Male; Particle Size; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Solubility

2006
Intra and inter-molecular interactions dictate the aggregation state of irinotecan co-encapsulated with floxuridine inside liposomes.
    Pharmaceutical research, 2008, Volume: 25, Issue:7

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Calorimetry; Camptothecin; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Cholesterol; Copper; Drug Carriers; Drug Compounding; Excipients; Floxuridine; Gluconates; Irinotecan; Liposomes; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Phosphatidylcholines; Phosphatidylglycerols; Solubility; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

2008
Formulation and comparative characterization of chitosan, gelatin, and chitosan-gelatin-coated liposomes of CPT-11-HCl.
    Drug development and industrial pharmacy, 2009, Volume: 35, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chemistry, Pharmaceutical; Chitosan; Cholesterol; Chromatography, High Pressure Liquid; Drug Carriers; Drug Compounding; Drug Stability; Electrochemistry; Freeze Fracturing; Gelatin; Irinotecan; Liposomes; Phosphatidylcholines

2009
Preparation of pegylated nano-liposomal formulation containing SN-38: In vitro characterization and in vivo biodistribution in mice.
    Acta pharmaceutica (Zagreb, Croatia), 2009, Volume: 59, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemistry, Pharmaceutical; Drug Stability; Female; Injections, Intravenous; Irinotecan; Liposomes; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Solubility; Technology, Pharmaceutical; Tissue Distribution

2009
The role of the transition metal copper and the ionophore A23187 in the development of Irinophore C™.
    Pharmaceutical research, 2011, Volume: 28, Issue:4

    Topics: Animals; Antineoplastic Agents; Calcimycin; Camptothecin; Cell Membrane Permeability; Chemistry, Pharmaceutical; Cholesterol; Chromatography, High Pressure Liquid; Copper; Female; Ionophores; Irinotecan; Liposomes; Mice; Mice, Inbred BALB C; Phosphatidylcholines

2011
Ultrasound triggered drug release from 10-hydroxycamptothecin-loaded phospholipid microbubbles for targeted tumor therapy in mice.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Sep-10, Volume: 162, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Male; Mice; Microbubbles; Neoplasms; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Sonication; Tumor Burden

2012
Enhanced active liposomal loading of a poorly soluble ionizable drug using supersaturated drug solutions.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Sep-10, Volume: 162, Issue:2

    Topics: Camptothecin; Drug Compounding; Hydrogen-Ion Concentration; Liposomes; Models, Theoretical; Organosilicon Compounds; Permeability; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Solubility; Solutions

2012
Nanocomposite liposomes containing quantum dots and anticancer drugs for bioimaging and therapeutic delivery: a comparison of cationic, PEGylated and deformable liposomes.
    Nanotechnology, 2013, Aug-16, Volume: 24, Issue:32

    Topics: Animals; Antineoplastic Agents; Calorimetry, Differential Scanning; Camptothecin; Cations; Cell Survival; Diagnostic Imaging; Drug Delivery Systems; Female; Irinotecan; Liposomes; Melanoma, Experimental; Mice; Mice, Nude; Nanocomposites; Particle Size; Phosphatidylcholines; Polyethylene Glycols; Quantum Dots; Spectrometry, Fluorescence; Static Electricity; Wound Healing

2013
Irinophore C™, a lipid nanoparticle formulation of irinotecan, abrogates the gastrointestinal effects of irinotecan in a rat model of clinical toxicities.
    Investigational new drugs, 2014, Volume: 32, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Cholesterol; Colon; Diarrhea; Disease Models, Animal; Drug Therapy, Combination; Female; Fluorouracil; Intestine, Small; Irinotecan; Liposomes; Nanoparticles; Phosphatidylcholines; Rats, Sprague-Dawley

2014
Redox-sensitive dimeric camptothecin phosphatidylcholines-based liposomes for improved anticancer efficacy.
    Nanomedicine (London, England), 2019, Volume: 14, Issue:23

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Survival; Drug Delivery Systems; Erythrocytes; Female; Humans; Liposomes; MCF-7 Cells; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Phosphatidylcholines; Polymers

2019
Interaction of Camptothecin with Model Cellular Membranes.
    Journal of chemical theory and computation, 2020, May-12, Volume: 16, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Membrane; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Molecular; Phosphatidylcholines

2020