Page last updated: 2024-09-05

phosphatidylcholines and bromhexine

phosphatidylcholines has been researched along with bromhexine in 18 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(bromhexine)
Trials
(bromhexine)
Recent Studies (post-2010) (bromhexine)
32,2044435,59359712681

Protein Interaction Comparison

ProteinTaxonomyphosphatidylcholines (IC50)bromhexine (IC50)
Cytochrome P450 2D6Homo sapiens (human)0.1958
Sodium-dependent serotonin transporterHomo sapiens (human)2.091
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.061

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199017 (94.44)18.7374
1990's0 (0.00)18.2507
2000's1 (5.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kock, HC; Merkus, JM; Roozen, PH; Verhoeven, AG1
Mears, GJ; Taylor, PJ; Van Petten, GR1
Gerner, R; Halberstadt, E; Schuhmann, R; Stein, WW1
Douste-Blazy, L; Prevost, MC; Soula, G1
Blümel, G; Haas, S; Krieglsteiner, P; Lohninger, A; Wriedt-Lübbe, I1
Egberts, J; Fontijne, P; Wamsteker, K1
Bierhalter, G; Kubli, F; Lorenz, U; Rüttgers, H; Schenk, D1
Abbà, L; Genghini, M; Knerich, R; Luisetti, M; Pagnoni, AM; Peona, V; Pozzi, E; Salmona, M; Villani, F1
Cretti, A; Skoczowska, W; Stepińska, J; Zbisławska, P1
Müller, B; von Wichert, P; Wilke, A1
Kai, H; Kojima, S; Miyata, T; Nakagawa, M; Okano, Y; Saito, M; Takahama, K1
Engler, H; Szelenyi, I1
Eberhardt, H; von Seefeld, H; Weiss, JM1
Renovanz, HD1
Meyer-Ingold, W; Reissmann, H; von Wichert, P; Wiegers, U1
Batenburg, JJ; Oldenborg, V; Post, M; Schuurmans, EA; van der Molen, AJ; van Golde, LM1
Brodecky, V; Maloney, JE1
Müller-Goymann, CC; Schubert, MA1

Trials

1 trial(s) available for phosphatidylcholines and bromhexine

ArticleYear
Surfactant in the amniotic fluid and bromhexine metabolite VIII.
    European journal of obstetrics, gynecology, and reproductive biology, 1978, Volume: 8, Issue:2

    Topics: Ambroxol; Amniotic Fluid; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Female; Gestational Age; Humans; Isoxsuprine; Obstetric Labor, Premature; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Sphingomyelins

1978

Other Studies

17 other study(ies) available for phosphatidylcholines and bromhexine

ArticleYear
The effects of NA872 on pulmonary maturation in the fetal lamb and rabbit.
    American journal of obstetrics and gynecology, 1978, Jan-01, Volume: 130, Issue:1

    Topics: Ambroxol; Animals; Blood Pressure; Body Fluids; Bromhexine; Female; Heart Rate; Lung; Lung Volume Measurements; Maternal-Fetal Exchange; Phosphatidylcholines; Pregnancy; Pressure; Pulmonary Surfactants; Rabbits; Seasons; Sheep; Sphingomyelins; Trachea

1978
[The effect of bromhexine metabolite VIII on lecithin synthesis in the rat lung (proceedings)].
    Archiv fur Gynakologie, 1977, Jul-29, Volume: 224, Issue:1-4

    Topics: Animals; Bromhexine; In Vitro Techniques; Lung; Phosphatidylcholines; Rats

1977
Biochemical modifications of pulmonary surfactant after bromhexine derivate injection.
    Respiration; international review of thoracic diseases, 1979, Volume: 37, Issue:4

    Topics: Animals; Bromhexine; Male; Palmitic Acids; Phosphatidylcholines; Phospholipids; Pulmonary Surfactants; Rabbits

1979
[Animal experiments on the effect of various drugs on the lecithin content and fibrinolytic activity of the fetal lung].
    Archives of gynecology, 1979, Jul-20, Volume: 228, Issue:1-4

    Topics: Ambroxol; Animals; Betamethasone; Bromhexine; Carnitine; Female; Lung; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Rats

1979
Indication of increase of the lecithin/sphingomyelin (L/S) ratio in lung fluid of lambs maternally treated with metabolite VIII of Bisolvon.
    Biology of the neonate, 1976, Volume: 29, Issue:5-6

    Topics: Ambroxol; Animals; Bromhexine; Exudates and Transudates; Female; Fetus; Lung; Maternal-Fetal Exchange; Phosphatidylcholines; Pregnancy; Sheep; Sphingomyelins; Stimulation, Chemical

1976
[Induction of surfactant formation in the fetal lung using bromhexine metabolite VIII].
    Archiv fur Gynakologie, 1975, Nov-18, Volume: 219, Issue:1-4

    Topics: Amniotic Fluid; Bromhexine; Enzyme Induction; Female; Humans; Infant, Newborn; Lung; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Sphingomyelins

1975
Ambroxol and pulmonary toxicity induced by antineoplastic drugs.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:2

    Topics: Ambroxol; Animals; Antineoplastic Agents; Bleomycin; Bromhexine; Busulfan; Cyclophosphamide; Humans; Lung Diseases; Lymphocytes; Macrophages; Methotrexate; Middle Aged; Neutrophils; Nitrosourea Compounds; Phosphatidylcholines; Procarbazine; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Respiratory Function Tests

1986
[Comparison of the effect of Lasolvan and betamethasone on lung maturity of fetal rabbits].
    Zentralblatt fur Gynakologie, 1989, Volume: 111, Issue:6

    Topics: Ambroxol; Animals; Betamethasone; Body Weight; Bromhexine; Female; Fetal Organ Maturity; Infusions, Intravenous; Lung; Organ Size; Phosphatidylcholines; Pregnancy; Rabbits; Sphingomyelins

1989
Ambroxol increases the choline but not fatty acid incorporation into lung phospholipids in experimental lung disorders.
    Respiration; international review of thoracic diseases, 1987, Volume: 52, Issue:2

    Topics: Ambroxol; Animals; Bromhexine; Choline; Fatty Acids; Female; Lung; Lung Diseases; Male; Peritonitis; Phosphatidylcholines; Phospholipids; Pulmonary Surfactants; Rabbits; Rats; Rats, Inbred Strains; Respiratory Distress Syndrome; Sphingomyelins

1987
[Effects of ambroxol on pulmonary surfactant--analysis of the fatty acid composition of phosphatidylcholine in the sputum and normal respiratory tract fluid in rabbits].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:1

    Topics: Ambroxol; Animals; Body Fluids; Bromhexine; Bronchi; Fatty Acids; Lung; Male; Phosphatidylcholines; Pulmonary Surfactants; Rabbits; Sputum

1986
Cytoprotective role of gastric surfactant in the ethanol-produced gastric mucosal injury of the rat.
    Pharmacology, 1986, Volume: 33, Issue:4

    Topics: Aluminum Hydroxide; Ambroxol; Animals; Bromhexine; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Male; Membrane Lipids; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Rats; Rats, Inbred Strains; Surface-Active Agents

1986
Stimulation of lung maturity: investigation of ambroxol in various animal models.
    Acta physiologica Hungarica, 1985, Volume: 65, Issue:3

    Topics: Ambroxol; Animals; Body Fluids; Bromhexine; Cells, Cultured; Fetal Organ Maturity; Lung; Lung Compliance; Phosphatidylcholines; Pulmonary Surfactants; Rabbits; Rats; Respiration; Sheep; Sphingomyelins; Time Factors; Trachea

1985
The anti-atelectasis factor considered in relation to Bisolvon and its metabolite VIII.
    Scandinavian journal of respiratory diseases. Supplementum, 1974, Volume: 90

    Topics: Amniotic Fluid; Aniline Compounds; Animals; Bromhexine; Cyclohexylamines; Female; Humans; Infant, Newborn; Lung; Maternal-Fetal Exchange; Mice; Phosphates; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Rabbits; Rats; Respiratory Distress Syndrome, Newborn; Stimulation, Chemical

1974
[Synthesis of water-soluble metabolites of cholin and incorporation of choline in phosphatidylcholine in the lungs of normal and ambroxol-pretreated rabbits].
    Praxis und Klinik der Pneumologie, 1984, Volume: 38, Issue:3

    Topics: Ambroxol; Animals; Bromhexine; Choline; Lung; Phosphatidylcholines; Phosphorylation; Phosphotransferases; Premedication; Rabbits

1984
The perfused rat lung as a model for studies on the formation of surfactant and the effect of Ambroxol on this process.
    Lung, 1983, Volume: 161, Issue:6

    Topics: Ambroxol; Animals; Bromhexine; Lung; Male; Models, Biological; Perfusion; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Pulmonary Surfactants; Rats; Rats, Inbred Strains

1983
Influence of the compound NA872 on cardiopulmonary maturation in the unanaesthetised fetal lamb.
    Biology of the neonate, 1980, Volume: 37, Issue:5-6

    Topics: Ambroxol; Amniotic Fluid; Animals; Blood Pressure; Bromhexine; Female; Fetal Heart; Fetus; Lung; Phosphatidylcholines; Pregnancy; Sheep; Sphingomyelins; Venous Pressure

1980
Solubilization of bromhexine hydrochloride in aqueous lecithin dispersions. Physicochemical characterization of interactions between drug and carrier.
    Die Pharmazie, 2001, Volume: 56, Issue:9

    Topics: Bromhexine; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Colloids; Drug Carriers; Emulsions; Expectorants; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning Transmission; Microscopy, Polarization; Particle Size; Phosphatidylcholines; Photons; Rheology; Surface Tension; Water; X-Ray Diffraction

2001