phosphatidylcholines has been researched along with aspirin in 32 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (aspirin) | Trials (aspirin) | Recent Studies (post-2010) (aspirin) |
|---|---|---|---|---|---|
| 32,204 | 443 | 5,593 | 48,947 | 6,817 | 13,778 |
| Protein | Taxonomy | phosphatidylcholines (IC50) | aspirin (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 0.35 | |
| Integrin beta-3 | Homo sapiens (human) | 5 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.8252 | |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | 1.375 | |
| Integrin alpha-IIb | Homo sapiens (human) | 5 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 2.271 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 2.4 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 2.15 | |
| Urotensin-2 receptor | Rattus norvegicus (Norway rat) | 0.3 | |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | 2.4 | |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.35 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 2.4081 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (43.75) | 18.7374 |
| 1990's | 5 (15.63) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 7 (21.88) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Champion, S; Haye, B; Jacquemin, C | 1 |
| Shier, WT | 1 |
| Balasubramanian, A; Krishnan, B; Ramakrishnan, S; Rao, AS | 1 |
| Aznar, J; Santos, MT; Valles, J | 1 |
| Rudofsky, G | 1 |
| Horrobin, DF; Huang, YS; Simmons, V; Watanabe, Y | 1 |
| Bastagli, L; Bernardi, P; Capelli, M; Cavazza, M; Clo', C; Fontana, F; Ghezzi, F; Grimaldi, R; Minelli, C; Ventura, C | 1 |
| Dimitrova, D; Ivancheva, E; Liochev, S; Russanov, E | 1 |
| Turinsky, J | 1 |
| Deykin, D; Snyder, D | 1 |
| LaMont, JT; Smith, BF | 1 |
| Adani, C; Bastagli, L; Bernardi, P; Cavazza, M; Minelli, C; Pecoraro, F; Vitolo, A | 2 |
| Glavinskaia, TA; Novikov, AI; Pavlova, LT | 1 |
| Gerrard, JM; Graff, G | 1 |
| Ramsden, JJ | 1 |
| Kurinets, A; Lichtenberger, LM | 1 |
| Huang, H; Jiang, X; Li, J; Ning, S; Peng, Y; Zhao, K; Zhou, M | 1 |
| Anand, BS; Lichtenberger, LM; Romero, JJ; Sanduja, SK | 1 |
| Boros, M; Ghyczy, M; Kaszaki, J; Szabó, A; Tiszlavicz, L; Zöllei, I | 1 |
| Akunda, JK; Darling, RL; Dial, EJ; Langenbach, R; Lichtenberger, LM; Romero, JJ | 1 |
| Dial, EJ; Doyen, JR; Lichtenberger, LM | 1 |
| Dial, EJ; Lichtenberger, LM; Romero, JJ | 1 |
| Hu, YL; Shen, Y; Wang, JM; Zhang, Y | 1 |
| Bhatt, DL; Cryer, B; Dong, JF; Lanza, FL; Lichtenberger, LM; Marathi, UK | 1 |
| Lichtenberger, LM; Okabe, S; Phan, T | 1 |
| Boggara, MB; Dial, EJ; Doyen, JR; Gorenstein, DG; Jayaraman, V; Krishnamoorti, R; Lichtenberger, LM; O'Neil, RG; Volk, DE; Zhou, Y | 1 |
| Alam, MM; Marella, A; Shaquiquzzaman, M; Verma, G | 1 |
| Bottsford-Miller, JN; Dial, EJ; Dorniak, PL; Fang, D; Filant, J; Haemmerle, M; Hansen, JM; Hatakeyama, H; Hu, W; Huang, Y; Lichtenberger, LM; Lyons, Y; Pradeep, S; Previs, RA; Shen, F; Sood, AK; Taylor, M; Wagner, MJ | 1 |
| Heqin, L; Hui, Y; Jiang, Y; Xiangping, Y | 1 |
| Lichtenberger, LM | 1 |
1 review(s) available for phosphatidylcholines and aspirin
| Article | Year |
|---|---|
Immunoinflammatory responses in gastrointestinal tract injury and recovery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Biogenic Polyamines; Biomarkers; Cyclooxygenase 2 Inhibitors; Gastrointestinal Tract; Humans; Infections; Inflammation; Inflammation Mediators; Inflammatory Bowel Diseases; Intestinal Mucosa; Lipoxins; Neoplasms; Nitric Oxide; Oxidative Stress; Phosphatidylcholines; Probiotics; Prostaglandins; Reactive Oxygen Species; Stomach Neoplasms | 2013 |
2 trial(s) available for phosphatidylcholines and aspirin
| Article | Year |
|---|---|
Phospholipid association reduces the gastric mucosal toxicity of aspirin in human subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Double-Blind Method; Female; Gastric Mucosa; Humans; Male; Phosphatidylcholines; Prostaglandin-Endoperoxide Synthases; Suspensions | 1999 |
Low-dose aspirin-induced ulceration is attenuated by aspirin-phosphatidylcholine: a randomized clinical trial.
Topics: Acute Disease; Administration, Oral; Aged; Aspirin; Drug Combinations; Female; Humans; Male; Middle Aged; Phosphatidylcholines; Platelet Aggregation Inhibitors; Prospective Studies; Single-Blind Method; Stomach Ulcer | 2011 |
29 other study(ies) available for phosphatidylcholines and aspirin
| Article | Year |
|---|---|
Stimulation by TSH of prostaglandin synthesis in pig thyroid.
Topics: Animals; Arachidonic Acids; Aspirin; Bucladesine; Cyclic AMP; Enzyme Activation; Indomethacin; Lipase; Phosphatidylcholines; Phosphatidylinositols; Phospholipases; Phospholipids; Prostaglandins; Swine; Thyroid Gland; Thyrotropin; Triglycerides | 1976 |
Inhibition of acyl coenzyme A:lysolecithin acyltransferases by local anesthetics, detergents and inhibitors of cyclic nucleotide phosphodiesterases.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acyltransferases; Anesthetics, Local; Animals; Aspirin; Cell Line; Detergents; Gastric Mucosa; Indomethacin; Liver; Mice; Myocardium; Phosphatidylcholines; Phosphodiesterase Inhibitors; Rabbits; Rats | 1977 |
Effect of acetyl salicylic acid (aspirin) on lung surfactant of rats.
Topics: Administration, Oral; Animals; Aspirin; Male; Phosphatidylcholines; Pulmonary Surfactants; Rats; Surface Tension | 1979 |
Effect of aspirin on platelet phospholipids.
Topics: Adult; Aspirin; Blood Platelets; Female; Humans; Male; Phosphatidylcholines; Phospholipids; Platelet Aggregation; Sphingomyelins | 1976 |
[Early detection and modification of preclinical arteriosclerosis].
Topics: Anticholesteremic Agents; Arteriosclerosis; Aspirin; Dipyridamole; Drug Therapy, Combination; Endothelium, Vascular; Follow-Up Studies; Humans; Muscle, Smooth, Vascular; Nafronyl; Phosphatidylcholines; Prospective Studies; Risk Factors; Ultrasonography | 1990 |
Fatty acid changes in liver choline and ethanolamine glycerophospholipids in aspirin-treated rats fed linoleate, gamma-linolenate and fish oil.
Topics: Animals; Aspirin; Dietary Fats; Fatty Acids, Unsaturated; Fish Oils; gamma-Linolenic Acid; Gastrointestinal Hemorrhage; Linoleic Acid; Linoleic Acids; Linolenic Acids; Liver; Male; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains | 1989 |
Effects of polyunsaturated fatty acids and prostaglandin synthesis on renal function.
Topics: Aspirin; Body Water; Dinoprostone; Fatty Acids, Unsaturated; Heart Failure; Humans; Injections, Intravenous; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Liver Cirrhosis; Lysine; Phosphatidylcholines; Prostaglandins; Prostaglandins E; Sodium | 1986 |
Phosphatidylcholine peroxidation induced by Cu(II) and some Cu(II) complexes.
Topics: Ascorbic Acid; Aspirin; Cimetidine; Copper; Glycine; Indomethacin; Lipid Peroxides; NAD; Oxidation-Reduction; Phosphatidylcholines | 1988 |
Phospholipids, prostaglandin E2, and proteolysis in denervated muscle.
Topics: Animals; Aspirin; Cardiolipins; Cycloheximide; Dinoprostone; Indomethacin; Lysophosphatidylcholines; Male; Muscle Denervation; Muscle Proteins; Muscles; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Prostaglandins E; Rats; Rats, Inbred Strains; Sphingomyelins; Tyrosine | 1986 |
Effect of epinephrine on platelet lipid metabolism.
Topics: Aspirin; Blood Platelets; Chromatography, Thin Layer; Depression, Chemical; Epinephrine; Glycerides; Humans; Lipids; Phosphatidylcholines; Phosphatidylinositols; Platelet Adhesiveness; Stimulation, Chemical; Triglycerides | 1973 |
The pathogenesis of gallstones.
Topics: Animals; Aspirin; Bile; Bile Acids and Salts; Cholelithiasis; Cholesterol; Cricetinae; Crystallization; Humans; Mucins; Phosphatidylcholines; Rodentia; Solubility | 1984 |
[Effect, on renal function, of a product rich in polyunsaturated fatty acids: results obtained in subjects with chronic renal failure caused by nephroangiosclerosis].
Topics: Aged; Aspirin; Fatty Acids, Unsaturated; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Nephrosclerosis; Phosphatidylcholines; Regional Blood Flow; Sodium | 1982 |
[Effect, on renal function, of a product rich in polyunsaturated fatty acids: results obtained in healthy subjects].
Topics: Aspirin; Fatty Acids, Unsaturated; Female; Glomerular Filtration Rate; Humans; Kidney; Lysine; Male; Phosphatidylcholines; Regional Blood Flow; Sodium | 1982 |
[Use of the preparation essentiale in the therapy of lupus erythematosus].
Topics: Adolescent; Adult; Aged; Aspirin; Chloroquine; Chronic Disease; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lipids; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Male; Middle Aged; Phosphatidylcholines; Prednisolone | 1983 |
1-arachidonyl-monoglyceride causes platelet aggregation: indirect evidence for an acylglycerol acylhydrolase involvement in the release of arachidonic acid for prostaglandin synthesis.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Glycerides; Humans; Indomethacin; Liposomes; Lysophospholipase; Phosphatidylcholines; Phospholipases; Platelet Aggregation; Prostaglandins | 1980 |
Partition coefficients of drugs in bilayer lipid membranes.
Topics: Aspirin; Caffeine; Lipid Bilayers; Phosphatidylcholines; Refractometry; Solubility | 1993 |
Phosphatidylcholine-associated aspirin accelerates healing of gastric ulcers in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Combinations; Male; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1998 |
An NMR study of the structural basis of the wide range of pharmacological functions of acetylsalicylic acid.
Topics: Aspirin; Liposomes; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Structure-Activity Relationship | 1999 |
Betaine-palmitate reduces acetylsalicylic acid-induced gastric damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Betaine; Drug Combinations; Gastric Mucosa; Gastrointestinal Agents; Male; Palmitic Acid; Palmitic Acids; Peptic Ulcer; Phosphatidylcholines; Rats; Rats, Wistar; Severity of Illness Index | 2001 |
The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Gastric Mucosa; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Knockout; Models, Animal; Peptic Ulcer; Phosphatidylcholines; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 2004 |
Phosphatidylcholine-associated nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit DNA synthesis and the growth of colon cancer cells in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Ibuprofen; Necrosis; Nucleic Acid Synthesis Inhibitors; Phosphatidylcholines | 2006 |
[Chronic inflammatory bowel diseases. Proven and innovative in the treatment].
Topics: Administration, Oral; Administration, Rectal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials, Phase II as Topic; Colitis, Ulcerative; Crohn Disease; Humans; Mesalamine; Phosphatidylcholines; Pilot Projects; Practice Guidelines as Topic; Remission Induction; Treatment Outcome; Trichuris | 2006 |
Surface phospholipids in gastric injury and protection when a selective cyclooxygenase-2 inhibitor (Coxib) is used in combination with aspirin.
Topics: Animals; Aspirin; Celecoxib; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Gastric Mucosa; Hydrophobic and Hydrophilic Interactions; Male; Phosphatidylcholines; Pyrazoles; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sulfonamides | 2007 |
Effects of Danshensu on maternal syndrome in phosphatidylserine/phosphatidylcholine microvesicle induced-mouse model: is it a candidate for preeclampsia remedy?
Topics: Animals; Anticoagulants; Aspirin; Disease Models, Animal; Female; Heparin; Lactates; Mice; Mice, Inbred ICR; Phosphatidylcholines; Phosphatidylserines; Placenta; Pre-Eclampsia; Pregnancy; Random Allocation; Thrombomodulin | 2010 |
Aspirin's ability to induce intestinal injury in rats is dependent on bile and can be reversed if pre-associated with phosphatidylcholine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile; Bile Acids and Salts; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Intestinal Mucosa; Intestine, Small; Male; Phosphatidylcholines; Rats; Rats, Sprague-Dawley | 2011 |
Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line, Tumor; Cell Membrane Permeability; Fluorescent Dyes; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Naproxen; Phosphatidylcholines; Pyridinium Compounds; Spectroscopy, Fourier Transform Infrared; Surface Plasmon Resonance | 2012 |
Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Biomarkers; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Hypoxia; Mice; Neovascularization, Pathologic; Ovarian Neoplasms; Phosphatidylcholines; Thromboxanes; Xenograft Model Antitumor Assays | 2016 |
Anti-inflammatory effect of a curcumin-aspirin derivative on Ureaplasma-induced cytokine expressions in neonatal monocytes.
Topics: Anti-Inflammatory Agents; Aspirin; Cell Survival; Curcumin; Cytokines; Humans; Infant, Newborn; Monocytes; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; RNA, Messenger; Toll-Like Receptors; Ureaplasma | 2018 |
Development of the PC-NSAID technology: From contact angle to Vazalore®.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Diseases; Humans; Phosphatidylcholines | 2023 |