Compounds > phosphatidylcholines
Page last updated: 2024-09-05

phosphatidylcholines and amitriptyline

phosphatidylcholines has been researched along with amitriptyline in 5 studies

Compound Research Comparison

Studies
(phosphatidylcholines)		Trials
(phosphatidylcholines)		Recent Studies (post-2010)
(phosphatidylcholines)		Studies
(amitriptyline)		Trials
(amitriptyline)		Recent Studies (post-2010) (amitriptyline)
32,2044435,5936,9351,3811,060

Protein Interaction Comparison

ProteinTaxonomyphosphatidylcholines (IC50)amitriptyline (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.006
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.023
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.081
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0053
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.3
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.3
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.3
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.044
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.3
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.008
Alpha-2A adrenergic receptorHomo sapiens (human)0.1755
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.3
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.011
D(2) dopamine receptorHomo sapiens (human)1.009
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.044
Alpha-2B adrenergic receptorHomo sapiens (human)0.004
Alpha-2C adrenergic receptorHomo sapiens (human)0.0295
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)1.02
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.026
D(1A) dopamine receptorHomo sapiens (human)0.355
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.0324
Histamine H2 receptorHomo sapiens (human)0.73
Alpha-1D adrenergic receptorHomo sapiens (human)0.105
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.015
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.006
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.02
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 6Rattus norvegicus (Norway rat)0.044
Sodium-dependent serotonin transporterHomo sapiens (human)0.2756
5-hydroxytryptamine receptor 7 Rattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 5ARattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 5BRattus norvegicus (Norway rat)0.044
Histamine H1 receptorHomo sapiens (human)0.0048
D(3) dopamine receptorHomo sapiens (human)0.182
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.044
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.07
Histamine H2 receptorCavia porcellus (domestic guinea pig)0.66
5-hydroxytryptamine receptor 6Homo sapiens (human)0.14
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)7.2446
Sodium channel protein type 5 subunit alphaHomo sapiens (human)1.6
Sodium channel protein type 9 subunit alphaHomo sapiens (human)4
5-hydroxytryptamine receptor 4 Rattus norvegicus (Norway rat)0.044
Sodium channel protein type 2 subunit alphaHomo sapiens (human)3.1
Sigma non-opioid intracellular receptor 1Homo sapiens (human)1.031
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.044

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Buscaglia, V; De Robertis, E; Stockert, M1
Debuch, H; Harder, A1
Cater, BR; Chapman, D; Hawes, SM; Saville, J1
Deo, N; Somasundaran, P; Somasundaran, T1
Bednarz, H; Ernst, R; Fatangare, A; Giampà, M; Kampa, JM; Niehaus, K; Riefke, B; Sahin, M; Slopianka, M1

Other Studies

5 other study(ies) available for phosphatidylcholines and amitriptyline

ArticleYear
In vivo action of phosphatidylserine, amitriptyline and stress on the binding of [3H]imipramine to membranes of the rat cerebral cortex.
    European journal of pharmacology, 1989, Jan-24, Volume: 160, Issue:1

    Topics: Amitriptyline; Animals; Cerebral Cortex; Imipramine; In Vitro Techniques; Male; Membranes; Phosphatidylcholines; Phosphatidylserines; Rats; Rats, Inbred Strains; Stress, Psychological

1989
Changes of transition temperatures of phosphatidylcholine and phosphatidylglycerol in presence of amphiphilic drugs.
    Chemistry and physics of lipids, 1986, Volume: 39, Issue:1-2

    Topics: Amitriptyline; Chlorpromazine; Imipramine; Models, Biological; Phosphatidylcholines; Phosphatidylglycerols; Propranolol; Structure-Activity Relationship; Thermodynamics

1986
Lipid phase transitions and drug interactions.
    Biochimica et biophysica acta, 1974, Aug-21, Volume: 363, Issue:1

    Topics: Amitriptyline; Binding Sites; Calorimetry; Desipramine; Electron Spin Resonance Spectroscopy; Imipramine; Kinetics; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Biological; Molecular Conformation; Morphinans; Morphine; Nortriptyline; Palmitic Acids; Phosphatidylcholines; Structure-Activity Relationship; Temperature; Thermodynamics

1974
Solution properties of amitriptyline and its partitioning into lipid bilayers.
    Colloids and surfaces. B, Biointerfaces, 2004, Apr-01, Volume: 34, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Dose-Response Relationship, Drug; Egg Yolk; Hydrogen-Ion Concentration; Ions; Lipid Bilayers; Liposomes; Models, Chemical; Phosphatidylcholines; Phospholipids; Spectrophotometry; Surface Properties; Temperature; Ultraviolet Rays

2004
Mass spectrometry imaging reveals lipid upregulation and bile acid changes indicating amitriptyline induced steatosis in a rat model.
    Toxicology letters, 2020, Jun-01, Volume: 325

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Lipid Metabolism; Liver; Male; Mass Spectrometry; Organ Size; Phosphatidylcholines; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Up-Regulation

2020